Keywords
Last Name
Institution

Lakshmi A. Devi

TitleDEAN FOR ACADEMIC DEVELOPMENT AND ENRICHMENT
InstitutionMount Sinai
Address
    Other Positions
    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentPharmacology and Systems Therapeutics

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentNeuroscience

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentPsychiatry


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sharma N, Ganesh D, Devi L, Srinivasan J, Ranga U. Prompt diagnosis and treatment of uterine arcuate artery pseudoaneurysm: a case report and review of literature. J Clin Diagn Res. 2013 Oct; 7(10):2303-6.
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    2. Stockton SD, Devi LA. An integrated quantitative proteomics and systems biology approach to explore synaptic protein profile changes during morphine exposure. Neuropsychopharmacology. 2014 Jan; 39(1):88-103.
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    3. Gomes I, Aryal DK, Wardman JH, Gupta A, Gagnidze K, Rodriguiz RM, Kumar S, Wetsel WC, Pintar JE, Fricker LD, Devi LA. GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding. Proc Natl Acad Sci U S A. 2013 Oct 1; 110(40):16211-6.
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    4. Devi L, Ohno M. Mechanisms that lessen benefits of ß-secretase reduction in a mouse model of Alzheimer's disease. Transl Psychiatry. 2013; 3:e284.
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    5. Gomes I, Fujita W, Gupta A, Saldanha AS, Negri A, Pinello CE, Roberts E, Filizola M, Hodder P, Devi LA. Identification of a µ-d opioid receptor heteromer-biased agonist with antinociceptive activity. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):12072-7.
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    6. Hernández-Gea V, Hilscher M, Rozenfeld R, Lim MP, Nieto N, Werner S, Devi LA, Friedman SL. Endoplasmic reticulum stress induces fibrogenic activity in hepatic stellate cells through autophagy. J Hepatol. 2013 Jul; 59(1):98-104.
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    7. Gomes I, Gupta A, Devi LA. G-protein-coupled heteromers: regulation in disease. Methods Enzymol. 2013; 521:219-38.
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    8. Gomes I, Fujita W, Chandrakala MV, Devi LA. Disease-specific heteromerization of G-protein-coupled receptors that target drugs of abuse. Prog Mol Biol Transl Sci. 2013; 117:207-65.
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    9. Bushlin I, Gupta A, Stockton SD, Miller LK, Devi LA. Dimerization with cannabinoid receptors allosterically modulates delta opioid receptor activity during neuropathic pain. PLoS One. 2012; 7(12):e49789.
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    10. Filizola M, Devi LA. Grand opening of structure-guided design for novel opioids. Trends Pharmacol Sci. 2013 Jan; 34(1):6-12.
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    11. Filizola M, Devi LA. Structural biology: How opioid drugs bind to receptors. Nature. 2012 May 17; 485(7398):314-7.
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    12. Costantino CM, Gomes I, Stockton SD, Lim MP, Devi LA. Opioid receptor heteromers in analgesia. Expert Rev Mol Med. 2012; 14:e9.
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    13. Costantino CM, Gupta A, Yewdall AW, Dale BM, Devi LA, Chen BK. Cannabinoid receptor 2-mediated attenuation of CXCR4-tropic HIV infection in primary CD4+ T cells. PLoS One. 2012; 7(3):e33961.
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    14. Rozenfeld R, Bushlin I, Gomes I, Tzavaras N, Gupta A, Neves S, Battini L, Gusella GL, Lachmann A, Ma'ayan A, Blitzer RD, Devi LA. Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons. PLoS One. 2012; 7(1):e29239.
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    15. Stockton SD, Devi LA. Functional relevance of µ-d opioid receptor heteromerization: a role in novel signaling and implications for the treatment of addiction disorders: from a symposium on new concepts in mu-opioid pharmacology. Drug Alcohol Depend. 2012 Mar 1; 121(3):167-72.
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    16. Berg KA, Rowan MP, Gupta A, Sanchez TA, Silva M, Gomes I, McGuire BA, Portoghese PS, Hargreaves KM, Devi LA, Clarke WP. Allosteric interactions between d and ? opioid receptors in peripheral sensory neurons. Mol Pharmacol. 2012 Feb; 81(2):264-72.
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    17. Miller LK, Hou X, Rodriguiz RM, Gagnidze K, Sweedler JV, Wetsel WC, Devi LA. Mice deficient in endothelin-converting enzyme-2 exhibit abnormal responses to morphine and altered peptide levels in the spinal cord. J Neurochem. 2011 Dec; 119(5):1074-85.
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    18. Abul-Husn NS, Annangudi SP, Ma'ayan A, Ramos-Ortolaza DL, Stockton SD, Gomes I, Sweedler JV, Devi LA. Chronic morphine alters the presynaptic protein profile: identification of novel molecular targets using proteomics and network analysis. PLoS One. 2011; 6(10):e25535.
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    19. Gupta A, Devi LA, Gomes I. Potentiation of µ-opioid receptor-mediated signaling by ketamine. J Neurochem. 2011 Oct; 119(2):294-302.
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    20. Narita M, Imai S, Nakamura A, Ozeki A, Asato M, Rahmadi M, Sudo Y, Hojo M, Uezono Y, Devi LA, Kuzumaki N, Suzuki T. Possible involvement of prolonging spinal µ-opioid receptor desensitization in the development of antihyperalgesic tolerance to µ-opioids under a neuropathic pain-like state. Addict Biol. 2013 Jul; 18(4):614-22.
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    21. Miller LK, Devi LA. The highs and lows of cannabinoid receptor expression in disease: mechanisms and their therapeutic implications. Pharmacol Rev. 2011 Sep; 63(3):461-70.
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    22. Lim MP, Devi LA, Rozenfeld R. Cannabidiol causes activated hepatic stellate cell death through a mechanism of endoplasmic reticulum stress-induced apoptosis. Cell Death Dis. 2011; 2:e170.
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    23. Rozenfeld R, Gupta A, Gagnidze K, Lim MP, Gomes I, Lee-Ramos D, Nieto N, Devi LA. AT1R-CB1R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II. EMBO J. 2011 Jun 15; 30(12):2350-63.
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    24. Imai S, Sudo Y, Nakamura A, Ozeki A, Asato M, Hojo M, Devi LA, Kuzumaki N, Suzuki T, Uezono Y, Narita M. Possible involvement of ß-endorphin in a loss of the coordinated balance of µ-opioid receptors trafficking processes by fentanyl. Synapse. 2011 Sep; 65(9):962-6.
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    25. Gomes I, Ijzerman AP, Ye K, Maillet EL, Devi LA. G protein-coupled receptor heteromerization: a role in allosteric modulation of ligand binding. Mol Pharmacol. 2011 Jun; 79(6):1044-52.
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    26. Golebiewska U, Johnston JM, Devi L, Filizola M, Scarlata S. Differential response to morphine of the oligomeric state of µ-opioid in the presence of d-opioid receptors. Biochemistry. 2011 Apr 12; 50(14):2829-37.
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    27. Rozenfeld R, Devi LA. Exploring a role for heteromerization in GPCR signalling specificity. Biochem J. 2011 Jan 1; 433(1):11-8.
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    28. LaRocca TJ, Schwarzkopf M, Altman P, Zhang S, Gupta A, Gomes I, Alvin Z, Champion HC, Haddad G, Hajjar RJ, Devi LA, Schecter AD, Tarzami ST. ß2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4. J Cardiovasc Pharmacol. 2010 Nov; 56(5):548-59.
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    29. Gomes I, Dale CS, Casten K, Geigner MA, Gozzo FC, Ferro ES, Heimann AS, Devi LA. Hemoglobin-derived peptides as novel type of bioactive signaling molecules. AAPS J. 2010 Dec; 12(4):658-69.
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    30. Ouimet T, Orng SV, Poras H, Gagnidze K, Devi LA, Fournié-Zaluski MC, Roques BP. Identification of an endothelin-converting enzyme-2-specific fluorigenic substrate and development of an in vitro and ex vivo enzymatic assay. J Biol Chem. 2010 Nov 5; 285(45):34390-400.
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    31. Gupta A, Mulder J, Gomes I, Rozenfeld R, Bushlin I, Ong E, Lim M, Maillet E, Junek M, Cahill CM, Harkany T, Devi LA. Increased abundance of opioid receptor heteromers after chronic morphine administration. Sci Signal. 2010; 3(131):ra54.
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    32. Hipser C, Bushlin I, Gupta A, Gomes I, Devi LA. Role of antibodies in developing drugs that target G-protein-coupled receptor dimers. Mt Sinai J Med. 2010 Jul-Aug; 77(4):374-80.
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    33. Khelashvili G, Dorff K, Shan J, Camacho-Artacho M, Skrabanek L, Vroling B, Bouvier M, Devi LA, George SR, Javitch JA, Lohse MJ, Milligan G, Neubig RR, Palczewski K, Parmentier M, Pin JP, Vriend G, Campagne F, Filizola M. GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. Bioinformatics. 2010 Jul 15; 26(14):1804-5.
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    34. Khosla AH, Devi L, Goel P, Saha PK. Puberty menorrhagia requiring inpatient admission. JNMA J Nepal Med Assoc. 2010 Apr-Jun; 49(178):112-6.
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    35. Morgan DJ, Wei S, Gomes I, Czyzyk T, Mzhavia N, Pan H, Devi LA, Fricker LD, Pintar JE. The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation. J Neurochem. 2010 Jun; 113(5):1275-84.
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    36. Rozenfeld R, Devi LA. Receptor heteromerization and drug discovery. Trends Pharmacol Sci. 2010 Mar; 31(3):124-30.
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    37. Ramos-Ortolaza DL, Bushlin I, Abul-Husn N, Annangudi SP, Sweedler J, Devi LA. Quantitative neuroproteomics of the synapse. Methods Mol Biol. 2010; 615:227-46.
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    38. Williams D, Devi LA. Escorts take the lead molecular chaperones as therapeutic targets. Prog Mol Biol Transl Sci. 2010; 91:121-49.
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    39. Morón JA, Gullapalli S, Taylor C, Gupta A, Gomes I, Devi LA. Modulation of opiate-related signaling molecules in morphine-dependent conditioned behavior: conditioned place preference to morphine induces CREB phosphorylation. Neuropsychopharmacology. 2010 Mar; 35(4):955-66.
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    40. Miller J, Agarwal A, Devi LA, Fontanini K, Hamilton JA, Pin JP, Shields DC, Spek CA, Sakmar TP, Kuliopulos A, Hunt SW. Insider access: pepducin symposium explores a new approach to GPCR modulation. Ann N Y Acad Sci. 2009 Nov; 1180 Suppl 1:E1-12.
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    41. Bushlin I, Rozenfeld R, Devi LA. Cannabinoid-opioid interactions during neuropathic pain and analgesia. Curr Opin Pharmacol. 2010 Feb; 10(1):80-6.
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    42. Abul-Husn NS, Bushlin I, Morón JA, Jenkins SL, Dolios G, Wang R, Iyengar R, Ma'ayan A, Devi LA. Systems approach to explore components and interactions in the presynapse. Proteomics. 2009 Jun; 9(12):3303-15.
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    43. Gomes I, Grushko JS, Golebiewska U, Hoogendoorn S, Gupta A, Heimann AS, Ferro ES, Scarlata S, Fricker LD, Devi LA. Novel endogenous peptide agonists of cannabinoid receptors. FASEB J. 2009 Sep; 23(9):3020-9.
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    44. Ferré S, Baler R, Bouvier M, Caron MG, Devi LA, Durroux T, Fuxe K, George SR, Javitch JA, Lohse MJ, Mackie K, Milligan G, Pfleger KD, Pin JP, Volkow ND, Waldhoer M, Woods AS, Franco R. Building a new conceptual framework for receptor heteromers. Nat Chem Biol. 2009 Mar; 5(3):131-4.
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    45. Alfaras-Melainis K, Gomes I, Rozenfeld R, Zachariou V, Devi L. Modulation of opioid receptor function by protein-protein interactions. Front Biosci (Landmark Ed). 2009; 14:3594-607.
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    46. Ellgren M, Artmann A, Tkalych O, Gupta A, Hansen HS, Hansen SH, Devi LA, Hurd YL. Dynamic changes of the endogenous cannabinoid and opioid mesocorticolimbic systems during adolescence: THC effects. Eur Neuropsychopharmacol. 2008 Nov; 18(11):826-34.
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    47. Décaillot FM, Rozenfeld R, Gupta A, Devi LA. Cell surface targeting of mu-delta opioid receptor heterodimers by RTP4. Proc Natl Acad Sci U S A. 2008 Oct 14; 105(41):16045-50.
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    48. Gupta A, Heimann AS, Gomes I, Devi LA. Antibodies against G-protein coupled receptors: novel uses in screening and drug development. Comb Chem High Throughput Screen. 2008 Jul; 11(6):463-7.
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    49. Rodriguiz RM, Gadnidze K, Ragnauth A, Dorr N, Yanagisawa M, Wetsel WC, Devi LA. Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory. Genes Brain Behav. 2008 Jun; 7(4):418-26.
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    50. Gagnidze K. Homology modeling and site-directed mutagenesis to identify selective inhibitors of endothelin-converting enzyme-2. J Med Chem. 2008 Jun 26; 51(12):3378-87.
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    51. Charlton JJ, Allen PB, Psifogeorgou K, Chakravarty S, Gomes I, Neve RL, Devi LA, Greengard P, Nestler EJ, Zachariou V. Multiple actions of spinophilin regulate mu opioid receptor function. Neuron. 2008 Apr 24; 58(2):238-47.
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    52. Iyengar R, Diverse-Pierluissi MA, Jenkins SL, Chan AM, Devi LA, Sobie EA, Ting AT, Weinstein DC. Inquiry learning. Integrating content detail and critical reasoning by peer review. Science. 2008 Feb 29; 319(5867):1189-90.
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    53. Rozenfeld R, Devi LA. Regulation of CB1 cannabinoid receptor trafficking by the adaptor protein AP-3. FASEB J. 2008 Jul; 22(7):2311-22.
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    54. Gupta A, Rozenfeld R, Gomes I, Raehal KM, Décaillot FM, Bohn LM, Devi LA. Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies. J Biol Chem. 2008 Apr 18; 283(16):10735-44.
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    55. Jenkins SL, Iyengar R, Diverse-Pierluissi MA, Chan AM, Devi LA, Sobie EA, Ting AT, Weinstein DC. Teaching resources. Using web-based discussion forums as a model of the peer-review process and a tool for assessment. Sci Signal. 2008; 1(9):tr2.
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    56. Heimann AS, Gomes I, Dale CS, Pagano RL, Gupta A, de Souza LL, Luchessi AD, Castro LM, Giorgi R, Rioli V, Ferro ES, Devi LA. Hemopressin is an inverse agonist of CB1 cannabinoid receptors. Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51):20588-93.
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    57. Rozenfeld R, Abul-Husn NS, Gomez I, Devi LA. An emerging role for the delta opioid receptor in the regulation of mu opioid receptor function. ScientificWorldJournal. 2007; 7:64-73.
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    58. Skrabanek L, Murcia M, Bouvier M, Devi L, George SR, Lohse MJ, Milligan G, Neubig R, Palczewski K, Parmentier M, Pin JP, Vriend G, Javitch JA, Campagne F, Filizola M. Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. BMC Bioinformatics. 2007; 8:177.
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    59. Morón JA, Devi LA. Use of proteomics for the identification of novel drug targets in brain diseases. J Neurochem. 2007 Jul; 102(2):306-15.
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    60. Rozenfeld R, Devi LA. Receptor heterodimerization leads to a switch in signaling: beta-arrestin2-mediated ERK activation by mu-delta opioid receptor heterodimers. FASEB J. 2007 Aug; 21(10):2455-65.
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    61. Pin JP, Neubig R, Bouvier M, Devi L, Filizola M, Javitch JA, Lohse MJ, Milligan G, Palczewski K, Parmentier M, Spedding M. International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacol Rev. 2007 Mar; 59(1):5-13.
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    62. Bolan EA, Kivell B, Jaligam V, Oz M, Jayanthi LD, Han Y, Sen N, Urizar E, Gomes I, Devi LA, Ramamoorthy S, Javitch JA, Zapata A, Shippenberg TS. D2 receptors regulate dopamine transporter function via an extracellular signal-regulated kinases 1 and 2-dependent and phosphoinositide 3 kinase-independent mechanism. Mol Pharmacol. 2007 May; 71(5):1222-32.
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    63. Harkany T, Guzmán M, Galve-Roperh I, Berghuis P, Devi LA, Mackie K. The emerging functions of endocannabinoid signaling during CNS development. Trends Pharmacol Sci. 2007 Feb; 28(2):83-92.
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    64. Gupta A, Décaillot FM, Gomes I, Tkalych O, Heimann AS, Ferro ES, Devi LA. Conformation state-sensitive antibodies to G-protein-coupled receptors. J Biol Chem. 2007 Feb 23; 282(8):5116-24.
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    65. Gendron L, Esdaile MJ, Mennicken F, Pan H, O'Donnell D, Vincent JP, Devi LA, Cahill CM, Stroh T, Beaudet A. Morphine priming in rats with chronic inflammation reveals a dichotomy between antihyperalgesic and antinociceptive properties of deltorphin. Neuroscience. 2007 Jan 5; 144(1):263-74.
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    66. Morón JA, Abul-Husn NS, Rozenfeld R, Dolios G, Wang R, Devi LA. Morphine administration alters the profile of hippocampal postsynaptic density-associated proteins: a proteomics study focusing on endocytic proteins. Mol Cell Proteomics. 2007 Jan; 6(1):29-42.
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    67. Premalata C, Devi L, Madhumathi DS, Appaji L. Chediak-Higashi syndrome masquerading as acute leukemia: the significance of lymphocyte inclusions. J Clin Oncol. 2006 Jul 20; 24(21):3505-7.
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    68. Gupta A, Devi LA. The use of receptor-specific antibodies to study G-protein-coupled receptors. Mt Sinai J Med. 2006 Jul; 73(4):673-81.
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    69. Rios C, Gomes I, Devi LA. mu opioid and CB1 cannabinoid receptor interactions: reciprocal inhibition of receptor signaling and neuritogenesis. Br J Pharmacol. 2006 Jun; 148(4):387-95.
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    70. Breit A, Gagnidze K, Devi LA, Lagacé M, Bouvier M. Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling. Mol Pharmacol. 2006 Aug; 70(2):686-96.
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    71. Chakraborty TR, Tkalych O, Nanno D, Garcia AL, Devi LA, Salton SR. Quantification of VGF- and pro-SAAS-derived peptides in endocrine tissues and the brain, and their regulation by diet and cold stress. Brain Res. 2006 May 17; 1089(1):21-32.
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    72. Abul-Husn NS, Devi LA. Neuroproteomics of the synapse and drug addiction. J Pharmacol Exp Ther. 2006 Aug; 318(2):461-8.
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    73. Gupta A, Décaillot FM, Devi LA. Targeting opioid receptor heterodimers: strategies for screening and drug development. AAPS J. 2006; 8(1):E153-9.
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    74. Pignatari GC, Rozenfeld R, Ferro ES, Oliveira L, Paiva AC, Devi LA. A role for transmembrane domains V and VI in ligand binding and maturation of the angiotensin II AT1 receptor. Biol Chem. 2006 Mar; 387(3):269-76.
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    75. Décaillot FM, Che FY, Fricker LD, Devi LA. Peptidomics of Cpefat/fat mouse hypothalamus and striatum: effect of chronic morphine administration. J Mol Neurosci. 2006; 28(3):277-84.
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    76. Fricker AD, Rios C, Devi LA, Gomes I. Serotonin receptor activation leads to neurite outgrowth and neuronal survival. Brain Res Mol Brain Res. 2005 Aug 18; 138(2):228-35.
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    77. He JC, Gomes I, Nguyen T, Jayaram G, Ram PT, Devi LA, Iyengar R. The G alpha(o/i)-coupled cannabinoid receptor-mediated neurite outgrowth involves Rap regulation of Src and Stat3. J Biol Chem. 2005 Sep 30; 280(39):33426-34.
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    78. Morgan DJ, Mzhavia N, Peng B, Pan H, Devi LA, Pintar JE. Embryonic gene expression and pro-protein processing of proSAAS during rodent development. J Neurochem. 2005 Jun; 93(6):1454-62.
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    79. Taylor C, Fricker AD, Devi LA, Gomes I. Mechanisms of action of antidepressants: from neurotransmitter systems to signaling pathways. Cell Signal. 2005 May; 17(5):549-57.
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    80. Pan H, Nanno D, Che FY, Zhu X, Salton SR, Steiner DF, Fricker LD, Devi LA. Neuropeptide processing profile in mice lacking prohormone convertase-1. Biochemistry. 2005 Mar 29; 44(12):4939-48.
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    81. Iyengar R, Diverse-Pierluissi M, Weinstein D, Devi LA. Teaching resources. Cell signaling systems: a course for graduate students. Sci STKE. 2005 Feb 1; 2005(269):tr3.
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    82. Jordan JD, He JC, Eungdamrong NJ, Gomes I, Ali W, Nguyen T, Bivona TG, Philips MR, Devi LA, Iyengar R. Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through G(alpha)o/i-triggered proteasomal degradation of Rap1GAPII. J Biol Chem. 2005 Mar 25; 280(12):11413-21.
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    83. Rios C, Gomes I, Devi LA. Interactions between delta opioid receptors and alpha-adrenoceptors. Clin Exp Pharmacol Physiol. 2004 Nov; 31(11):833-6.
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    84. Pan H, Mzhavia N, Devi LA. Endothelin converting enzyme-2: a processing enzyme involved in the generation of novel neuropeptides. Protein Pept Lett. 2004 Oct; 11(5):461-9.
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    85. Gomes I, Gupta A, Filipovska J, Szeto HH, Pintar JE, Devi LA. A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia. Proc Natl Acad Sci U S A. 2004 Apr 6; 101(14):5135-9.
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    86. Wei S, Feng Y, Che FY, Pan H, Mzhavia N, Devi LA, McKinzie AA, Levin N, Richards WG, Fricker LD. Obesity and diabetes in transgenic mice expressing proSAAS. J Endocrinol. 2004 Mar; 180(3):357-68.
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    87. Jordan BA, Gomes I, Rios C, Filipovska J, Devi LA. Functional interactions between mu opioid and alpha 2A-adrenergic receptors. Mol Pharmacol. 2003 Dec; 64(6):1317-24.
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    88. Mzhavia N, Pan H, Che FY, Fricker LD, Devi LA. Characterization of endothelin-converting enzyme-2. Implication for a role in the nonclassical processing of regulatory peptides. J Biol Chem. 2003 Apr 25; 278(17):14704-11.
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    89. Gomes I, Filipovska J, Devi LA. Opioid receptor oligomerization. Detection and functional characterization of interacting receptors. Methods Mol Med. 2003; 84:157-83.
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    90. Filipovska J, Gomes I, Xu W, Chen C, Liu-Chen LY, Devi LA. Recombinant opioid receptors. Structure-function relationship. Methods Mol Med. 2003; 84:185-203.
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    91. Boudarine M, Yegorov O, Sterling-Dubrovsky A, Devi LA, Berman Y. Developmental changes in opioid peptides and their receptors in Cpe(fat)/Cpe(fat) mice lacking peptide processing enzyme carboxypeptidase E. J Pharmacol Exp Ther. 2002 Dec; 303(3):1317-24.
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    92. Gomes I, Filipovska J, Jordan BA, Devi LA. Oligomerization of opioid receptors. Methods. 2002 Aug; 27(4):358-65.
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    93. Mzhavia N, Qian Y, Feng Y, Che FY, Devi LA, Fricker LD. Processing of proSAAS in neuroendocrine cell lines. Biochem J. 2002 Jan 1; 361(Pt 1):67-76.
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    94. Rios CD, Jordan BA, Gomes I, Devi LA. G-protein-coupled receptor dimerization: modulation of receptor function. Pharmacol Ther. 2001 Nov-Dec; 92(2-3):71-87.
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    95. Devi LA. Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking. Trends Pharmacol Sci. 2001 Oct; 22(10):532-7.
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    96. Che FY, Yan L, Li H, Mzhavia N, Devi LA, Fricker LD. Identification of peptides from brain and pituitary of Cpe(fat)/Cpe(fat) mice. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9971-6.
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    97. Basak A, Koch P, Dupelle M, Fricker LD, Devi LA, Chrétien M, Seidah NG. Inhibitory specificity and potency of proSAAS-derived peptides toward proprotein convertase 1. J Biol Chem. 2001 Aug 31; 276(35):32720-8.
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    98. Gomes I, Jordan BA, Gupta A, Rios C, Trapaidze N, Devi LA. G protein coupled receptor dimerization: implications in modulating receptor function. J Mol Med (Berl). 2001 Jun; 79(5-6):226-42.
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    99. Berman Y, Mzhavia N, Polonskaia A, Devi LA. Impaired prohormone convertases in Cpe(fat)/Cpe(fat) mice. J Biol Chem. 2001 Jan 12; 276(2):1466-73.
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    100. Jordan BA, Trapaidze N, Gomes I, Nivarthi R, Devi LA. Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation. Proc Natl Acad Sci U S A. 2001 Jan 2; 98(1):343-8.
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    101. Mzhavia N, Berman Y, Che FY, Fricker LD, Devi LA. ProSAAS processing in mouse brain and pituitary. J Biol Chem. 2001 Mar 2; 276(9):6207-13.
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    102. Gomes I, Jordan BA, Gupta A, Trapaidze N, Nagy V, Devi LA. Heterodimerization of mu and delta opioid receptors: A role in opiate synergy. J Neurosci. 2000 Nov 15; 20(22):RC110.
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    103. Guo J, Wu Y, Zhang W, Zhao J, Devi LA, Pei G, Ma L. Identification of G protein-coupled receptor kinase 2 phosphorylation sites responsible for agonist-stimulated delta-opioid receptor phosphorylation. Mol Pharmacol. 2000 Nov; 58(5):1050-6.
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    104. Jordan BA, Cvejic S, Devi LA. Opioids and their complicated receptor complexes. Neuropsychopharmacology. 2000 Oct; 23(4 Suppl):S5-S18.
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    105. Devi LA, Brady LS. Dimerization of G-protein coupled receptors. Neuropsychopharmacology. 2000 Oct; 23(4 Suppl):S3-4.
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    106. Berman Y, Mzhavia N, Polonskaia A, Furuta M, Steiner DF, Pintar JE, Devi LA. Defective prodynorphin processing in mice lacking prohormone convertase PC2. J Neurochem. 2000 Oct; 75(4):1763-70.
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    107. Devi LA. G-protein-coupled receptor dimers in the lime light. Trends Pharmacol Sci. 2000 Sep; 21(9):324-6.
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    108. Qian Y, Devi LA, Mzhavia N, Munzer S, Seidah NG, Fricker LD. The C-terminal region of proSAAS is a potent inhibitor of prohormone convertase 1. J Biol Chem. 2000 Aug 4; 275(31):23596-601.
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    109. Gomes I, Trapaidze N, Turndorf H, Devi LA, Bansinath M. Acute ethanol treatment modulates delta opioid receptors in N18TG2 cells. Anesthesiology. 2000 Jun; 92(6):1789-98.
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    110. Trapaidze N, Gomes I, Bansinath M, Devi LA. Recycling and resensitization of delta opioid receptors. DNA Cell Biol. 2000 Apr; 19(4):195-204.
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    111. Trapaidze N, Gomes I, Cvejic S, Bansinath M, Devi LA. Opioid receptor endocytosis and activation of MAP kinase pathway. Brain Res Mol Brain Res. 2000 Mar 29; 76(2):220-8.
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    112. Trapaidze N, Cvejic S, Nivarthi RN, Abood M, Devi LA. Role for C-tail residues in delta opioid receptor downregulation. DNA Cell Biol. 2000 Feb; 19(2):93-101.
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    113. Fricker LD, McKinzie AA, Sun J, Curran E, Qian Y, Yan L, Patterson SD, Courchesne PL, Richards B, Levin N, Mzhavia N, Devi LA, Douglass J. Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing. J Neurosci. 2000 Jan 15; 20(2):639-48.
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    114. Jordan BA, Cvejic S, Devi LA. Kappa opioid receptor endocytosis by dynorphin peptides. DNA Cell Biol. 2000 Jan; 19(1):19-27.
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    115. Harrison C, McNulty S, Smart D, Rowbotham DJ, Grandy DK, Devi LA, Lambert DG. The effects of endomorphin-1 and endomorphin-2 in CHO cells expressing recombinant mu-opioid receptors and SH-SY5Y cells. Br J Pharmacol. 1999 Sep; 128(2):472-8.
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    116. Harrison C, Rowbotham DJ, Devi LA, Lambert DG. The effect of C-terminal truncation of the recombinant delta-opioid receptor on Ca2+i signaling. Eur J Pharmacol. 1999 Aug 27; 379(2-3):237-42.
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    117. Jordan BA, Devi LA. G-protein-coupled receptor heterodimerization modulates receptor function. Nature. 1999 Jun 17; 399(6737):697-700.
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    118. Liuzzo JP, Petanceska SS, Moscatelli D, Devi LA. Inflammatory mediators regulate cathepsin S in macrophages and microglia: A role in attenuating heparan sulfate interactions. Mol Med. 1999 May; 5(5):320-33.
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    119. Liuzzo JP, Petanceska SS, Devi LA. Neurotrophic factors regulate cathepsin S in macrophages and microglia: A role in the degradation of myelin basic protein and amyloid beta peptide. Mol Med. 1999 May; 5(5):334-43.
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    120. Berman Y, Juliano L, Devi LA. Specificity of the dynorphin-processing endoprotease: comparison with prohormone convertases. J Neurochem. 1999 May; 72(5):2120-6.
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    121. Mzhavia N, Berman YL, Qian Y, Yan L, Devi LA. Cloning, expression, and characterization of human metalloprotease 1: a novel member of the pitrilysin family of metalloendoproteases. DNA Cell Biol. 1999 May; 18(5):369-80.
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    122. Berman Y, Ageyeva L, Veksler B, Wood D, Devi LA. Dynorphin A processing enzyme: tissue distribution, isolation, and characterization. J Biochem. 1999 Mar; 125(3):641-7.
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    123. Hirota K, Okawa H, Appadu BL, Grandy DK, Devi LA, Lambert DG. Stereoselective interaction of ketamine with recombinant mu, kappa, and delta opioid receptors expressed in Chinese hamster ovary cells. Anesthesiology. 1999 Jan; 90(1):174-82.
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    124. Wood DE, Thomas A, Devi LA, Berman Y, Beavis RC, Reed JC, Newcomb EW. Bax cleavage is mediated by calpain during drug-induced apoptosis. Oncogene. 1998 Sep 3; 17(9):1069-78.
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    125. Jordan B, Devi LA. Molecular mechanisms of opioid receptor signal transduction. Br J Anaesth. 1998 Jul; 81(1):12-9.
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    126. Hirst RA, Smart D, Devi LA, Lambert DG. Effects of C-terminal truncation of the recombinant delta-opioid receptor on phospholipase C and adenylyl cyclase coupling. J Neurochem. 1998 Jun; 70(6):2273-8.
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    127. Wei L, Berman Y, Castaño EM, Cadene M, Beavis RC, Devi L, Levy E. Instability of the amyloidogenic cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type. J Biol Chem. 1998 May 8; 273(19):11806-14.
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    128. Cvejic S, Devi LA. Dimerization of the delta opioid receptor: implication for a role in receptor internalization. J Biol Chem. 1997 Oct 24; 272(43):26959-64.
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    129. Berman Y, Devi L, Spangler R, Kreek MJ, Carr KD. Chronic food restriction and streptozotocin-induced diabetes differentially alter prodynorphin mRNA levels in rat brain regions. Brain Res Mol Brain Res. 1997 Jun; 46(1-2):25-30.
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    130. Fricker LD, Berman YL, Leiter EH, Devi LA. Carboxypeptidase E activity is deficient in mice with the fat mutation. Effect on peptide processing. J Biol Chem. 1996 Nov 29; 271(48):30619-24.
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    131. Trapaidze N, Keith DE, Cvejic S, Evans CJ, Devi LA. Sequestration of the delta opioid receptor. Role of the C terminus in agonist-mediated internalization. J Biol Chem. 1996 Nov 15; 271(46):29279-85.
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    132. Lakshminarasimhan S, Doval DC, Rajashekhar U, Mukherjee G, Kannan V, Devi L, Bapsy PP. Pre leukemic granulocytic sarcoma of vagina. A case report with review of literature. Indian J Cancer. 1996 Sep; 33(3):145-8.
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    133. Cvejic S, Trapaidze N, Cyr C, Devi LA. Thr353, located within the COOH-terminal tail of the delta opiate receptor, is involved in receptor down-regulation. J Biol Chem. 1996 Feb 23; 271(8):4073-6.
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    134. Petanceska S, Canoll P, Devi LA. Expression of rat cathepsin S in phagocytic cells. J Biol Chem. 1996 Feb 23; 271(8):4403-9.
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    135. Cyr CR, Devi LA, Rudy B, Kris RM. Heterologous desensitization of the human endothelin A and neurokinin A receptors in Xenopus laevis oocytes. Recept Signal Transduct. 1996; 6(2):99-109.
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    136. Berman YL, Juliano L, Devi LA. Purification and characterization of a dynorphin-processing endopeptidase. J Biol Chem. 1995 Oct 6; 270(40):23845-50.
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    137. Berman Y, Devi L, Carr KD. Effects of streptozotocin-induced diabetes on prodynorphin-derived peptides in rat brain regions. Brain Res. 1995 Jul 10; 685(1-2):129-34.
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    138. Berman Y, Devi L, Carr KD. Effects of chronic food restriction on prodynorphin-derived peptides in rat brain regions. Brain Res. 1994 Nov 21; 664(1-2):49-53.
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    139. Devi L, Petanceska S, Liu R, Arbabha B, Bansinath M, Garg U. Regulation of neuropeptide-processing enzymes by nitric oxide in cultured astrocytes. J Neurochem. 1994 Jun; 62(6):2387-93.
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    140. Petanceska S, Burke S, Watson SJ, Devi L. Differential distribution of messenger RNAs for cathepsins B, L and S in adult rat brain: an in situ hybridization study. Neuroscience. 1994 Apr; 59(3):729-38.
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    141. Berman YL, Rattan AK, Carr K, Devi L. Regional distribution of neuropeptide processing endopeptidases in adult rat brain. Biochimie. 1994; 76(3-4):245-50.
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    142. Fricker LD, Devi L. Posttranslational processing of carboxypeptidase E, a neuropeptide-processing enzyme, in AtT-20 cells and bovine pituitary secretory granules. J Neurochem. 1993 Oct; 61(4):1404-15.
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    143. Grigoriants O, Devi L, Fricker LD. Dopamine antagonist haloperidol increases carboxypeptidase E mRNA in rat neurointermediate pituitary but not in various other rat tissues. Brain Res Mol Brain Res. 1993 Jul; 19(1-2):161-4.
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    144. Petanceska S, Zikherman J, Fricker LD, Devi L. Processing of prodynorphin in BRL-3A cells, a rat liver-derived cell line: implications for the specificity of neuropeptide-processing enzymes. Mol Cell Endocrinol. 1993 Jul; 94(1):37-45.
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    145. Devi L. Tissue distribution of a dynorphin-processing endopeptidase. Endocrinology. 1993 Mar; 132(3):1139-44.
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    146. Ernst M, Devi L, Silva RR, Gonzalez NM, Small AM, Malone RP, Campbell M. Plasma beta-endorphin levels, naltrexone, and haloperidol in autistic children. Psychopharmacol Bull. 1993; 29(2):221-7.
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    147. Petanceska S, Devi L. Sequence analysis, tissue distribution, and expression of rat cathepsin S. J Biol Chem. 1992 Dec 25; 267(36):26038-43.
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    148. Garg UC, Devi L, Turndorf H, Goldfrank LR, Bansinath M. Effect of nitric oxide on mitogenesis and proliferation of cerebellar glial cells. Brain Res. 1992 Oct 2; 592(1-2):208-12.
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    149. Devi L. Secretion and regulation of a neuropeptide-processing enzyme by AtT-20 cells. Endocrinology. 1992 Oct; 131(4):1930-5.
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    150. Greco L, Daly L, Kim S, Devi L. Dynorphin-processing endopeptidase in the rat anterior pituitary lactotrophic cell line, GH4C1. Neuroendocrinology. 1992 Mar; 55(3):351-6.
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    151. Devi L. Consensus sequence for processing of peptide precursors at monobasic sites. FEBS Lett. 1991 Mar 25; 280(2):189-94.
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    152. Devi L, Gupta P, Fricker LD. Subcellular localization, partial purification, and characterization of a dynorphin processing endopeptidase from bovine pituitary. J Neurochem. 1991 Jan; 56(1):320-9.
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    153. Devi L. Characterization of a dynorphin converting enzyme in the bovine pituitary. Prog Clin Biol Res. 1990; 328:247-51.
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    154. Fricker LD, Devi L. Comparison of a spectrophotometric, a fluorometric, and a novel radiometric assay for carboxypeptidase E (EC 3.4.17.10) and other carboxypeptidase B-like enzymes. Anal Biochem. 1990 Jan; 184(1):21-7.
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    155. Devi L, Gupta P, Douglass J. Expression and posttranslational processing of preprodynorphin complementary DNA in the mouse anterior pituitary cell line AtT-20. Mol Endocrinol. 1989 Nov; 3(11):1852-60.
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    156. Devi L, Gupta P. Expression and Post-Translational Processing of Preprodynorphin in the Rat Anterior Pituitary Cell Line, GH4C1. J Neuroendocrinol. 1989 Oct 1; 1(5):363-8.
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    157. McMurray CT, Devi L, Calavetta L, Douglass JO. Regulated expression of the prodynorphin gene in the R2C Leydig tumor cell line. Endocrinology. 1989 Jan; 124(1):49-59.
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    158. Devi L, Douglass J, Herbert E. A solution hybridization assay for the quantitation of prodynorphin mRNA. Brain Res. 1987 Jul; 388(2):173-6.
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    159. Devi L, Goldstein A. Conversion of leumorphin (dynorphin B-29) to dynorphin B and dynorphin B-14 by thiol protease activity. J Neurochem. 1986 Jul; 47(1):154-7.
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    160. Devi L, Goldstein A. Opioid and other peptides as inhibitors of leumorphin (dynorphin B-29) converting activity. Peptides. 1986 Jan-Feb; 7(1):87-90.
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    161. Devi L, Goldstein A. Neuropeptide processing by single-step cleavage: conversion of leumorphin (dynorphin B-29) to dynorphin B. Biochem Biophys Res Commun. 1985 Aug 15; 130(3):1168-76.
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    162. Devi L, Goldstein A. Dynorphin converting enzyme with unusual specificity from rat brain. Proc Natl Acad Sci U S A. 1984 Mar; 81(6):1892-6.
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    163. George G, Devi L. Stromatosis (endolymphatic stromal myosis). A case report with review of the literature. J Postgrad Med. 1969 Jul; 15(3):136-9.
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