Keywords
Last Name
Institution

Li Sun

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentEndocrinology, Diabetes and Bone Disease
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Baliram R, Chow A, Huber AK, Collier L, Ali MR, Morshed SA, Latif R, Teixeira A, Merad M, Liu L, Sun L, Blair HC, Zaidi M, Davies TF. Thyroid and Bone: Macrophage-Derived TSH-ß Splice Variant Increases Murine Osteoblastogenesis. Endocrinology. 2013 Dec; 154(12):4919-26.
      View in: PubMed
    2. Sun L, Zhu LL, Lu P, Yuen T, Li J, Ma R, Baliram R, Baliram R, Moonga SS, Liu P, Zallone A, New MI, Davies TF, Zaidi M. Genetic confirmation for a central role for TNFa in the direct action of thyroid stimulating hormone on the skeleton. Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24):9891-6.
      View in: PubMed
    3. Qin W, Sun L, Cao J, Peng Y, Collier L, Wu Y, Creasey G, Li J, Qin Y, Jarvis J, Bauman WA, Zaidi M, Cardozo C. The central nervous system (CNS)-independent anti-bone-resorptive activity of muscle contraction and the underlying molecular and cellular signatures. J Biol Chem. 2013 May 10; 288(19):13511-21.
      View in: PubMed
    4. Sun L, Pan J, Peng Y, Wu Y, Li J, Liu X, Qin Y, Bauman WA, Cardozo C, Zaidi M, Qin W. Anabolic steroids reduce spinal cord injury-related bone loss in rats associated with increased Wnt signaling. J Spinal Cord Med. 2013 Nov; 36(6):616-22.
      View in: PubMed
    5. New MI, Abraham M, Gonzalez B, Dumic M, Razzaghy-Azar M, Chitayat D, Sun L, Zaidi M, Wilson RC, Yuen T. Genotype-phenotype correlation in 1,507 families with congenital adrenal hyperplasia owing to 21-hydroxylase deficiency. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):2611-6.
      View in: PubMed
    6. Baliram R, Sun L, Cao J, Li J, Latif R, Huber AK, Yuen T, Blair HC, Zaidi M, Davies TF. Hyperthyroid-associated osteoporosis is exacerbated by the loss of TSH signaling. J Clin Invest. 2012 Oct 1; 122(10):3737-41.
      View in: PubMed
    7. Zhu LL, Blair H, Cao J, Yuen T, Latif R, Guo L, Tourkova IL, Li J, Davies TF, Sun L, Bian Z, Rosen C, Zallone A, New MI, Zaidi M. Blocking antibody to the ß-subunit of FSH prevents bone loss by inhibiting bone resorption and stimulating bone synthesis. Proc Natl Acad Sci U S A. 2012 Sep 4; 109(36):14574-9.
      View in: PubMed
    8. Colaianni G, Sun L, Di Benedetto A, Tamma R, Zhu LL, Cao J, Grano M, Yuen T, Colucci S, Cuscito C, Mancini L, Li J, Nishimori K, Bab I, Lee HJ, Iqbal J, Young WS, Rosen C, Zallone A, Zaidi M. Bone marrow oxytocin mediates the anabolic action of estrogen on the skeleton. J Biol Chem. 2012 Aug 17; 287(34):29159-67.
      View in: PubMed
    9. Yuen T, Iqbal J, Zhu LL, Sun L, Lin A, Zhao H, Liu J, Mistry PK, Zaidi M. Disease-drug pairs revealed by computational genomic connectivity mapping on GBA1 deficient, Gaucher disease mice. Biochem Biophys Res Commun. 2012 Jun 15; 422(4):573-7.
      View in: PubMed
    10. Zaidi M, Buettner C, Sun L, Iqbal J. Minireview: The link between fat and bone: does mass beget mass? Endocrinology. 2012 May; 153(5):2070-5.
      View in: PubMed
    11. Zaidi M, Sun L, Blair HC. Special stem cells for bone. Cell Stem Cell. 2012 Mar 2; 10(3):233-4.
      View in: PubMed
    12. Iqbal J, Sun L, Mechanick JI, Zaidi M. Anti-cancer actions of denosumab. Curr Osteoporos Rep. 2011 Dec; 9(4):173-6.
      View in: PubMed
    13. Baliram R, Latif R, Berkowitz J, Frid S, Colaianni G, Sun L, Zaidi M, Davies TF. Thyroid-stimulating hormone induces a Wnt-dependent, feed-forward loop for osteoblastogenesis in embryonic stem cell cultures. Proc Natl Acad Sci U S A. 2011 Sep 27; 108(39):16277-82.
      View in: PubMed
    14. Zaidi M, Sun L, Iqbal J. The pituitary-bone axis. Adv Exp Med Biol. 2011; 707:119-23.
      View in: PubMed
    15. Arora S, Agrawal M, Sun L, Duffoo F, Zaidi M, Iqbal J. HIV and bone loss. Curr Osteoporos Rep. 2010 Dec; 8(4):219-26.
      View in: PubMed
    16. Iqbal J, Sun L, Zaidi M. Denosumab for the treatment of osteoporosis. Curr Osteoporos Rep. 2010 Dec; 8(4):163-7.
      View in: PubMed
    17. Agrawal M, Zhu G, Sun L, Zaidi M, Iqbal J. The role of FSH and TSH in bone loss and its clinical relevance. Curr Osteoporos Rep. 2010 Dec; 8(4):205-11.
      View in: PubMed
    18. Mechanick JI, Sun L, Zaidi M. Introduction to Molecular and Integrative Physiology of the Musculoskeletal System. Ann N Y Acad Sci. 2010 Nov; 1211:1-2.
      View in: PubMed
    19. Sun M, Iqbal J, Singh S, Sun L, Zaidi M. The crossover of bisphosphonates to cancer therapy. Ann N Y Acad Sci. 2010 Nov; 1211:107-12.
      View in: PubMed
    20. Leong DJ, Li YH, Gu XI, Sun L, Zhou Z, Nasser P, Laudier DM, Iqbal J, Majeska RJ, Schaffler MB, Goldring MB, Cardoso L, Zaidi M, Sun HB. Physiological loading of joints prevents cartilage degradation through CITED2. FASEB J. 2011 Jan; 25(1):182-91.
      View in: PubMed
    21. Zaidi M, Iqbal J, Sun L. New horizons in skeletal physiology and pathophysiology. Endocr Pract. 2010 Sep-Oct; 16(5):874-81.
      View in: PubMed
    22. Iqbal J, Sun L, Zaidi M. Commentary-FSH and bone 2010: evolving evidence. Eur J Endocrinol. 2010 Jul; 163(1):173-6.
      View in: PubMed
    23. Zaidi M, Sun L, Robinson LJ, Tourkova IL, Liu L, Wang Y, Zhu LL, Liu X, Li J, Peng Y, Yang G, Shi X, Levine A, Iqbal J, Yaroslavskiy BB, Isales C, Blair HC. ACTH protects against glucocorticoid-induced osteonecrosis of bone. Proc Natl Acad Sci U S A. 2010 May 11; 107(19):8782-7.
      View in: PubMed
    24. Iqbal J, Sun L, Zaidi M. Complexity in signal transduction. Ann N Y Acad Sci. 2010 Mar; 1192:238-44.
      View in: PubMed
    25. Sun L, Zhang Z, Zhu LL, Peng Y, Liu X, Li J, Agrawal M, Robinson LJ, Iqbal J, Blair HC, Zaidi M. Further evidence for direct pro-resorptive actions of FSH. Biochem Biophys Res Commun. 2010 Mar 26; 394(1):6-11.
      View in: PubMed
    26. Zaidi M, Turner CH, Canalis E, Pacifici R, Sun L, Iqbal J, Guo XE, Silverman S, Epstein S, Rosen CJ. Bone loss or lost bone: rationale and recommendations for the diagnosis and treatment of early postmenopausal bone loss. Curr Osteoporos Rep. 2009 Dec; 7(4):118-26.
      View in: PubMed
    27. Imam A, Iqbal J, Blair HC, Davies TF, Huang CL, Zallone A, Zaidi M, Sun L. Role of the pituitary-bone axis in skeletal pathophysiology. Curr Opin Endocrinol Diabetes Obes. 2009 Dec; 16(6):423-9.
      View in: PubMed
    28. Zaidi M, Iqbal J, Blair HC, Zallone A, Davies T, Sun L. Paradigm shift in the pathophysiology of postmenopausal and thyrotoxic osteoporosis. Mt Sinai J Med. 2009 Oct; 76(5):474-83.
      View in: PubMed
    29. Liu X, Shimono K, Zhu LL, Li J, Peng Y, Imam A, Iqbal J, Moonga S, Colaianni G, Su C, Lu Z, Iwamoto M, Pacifici M, Zallone A, Sun L, Zaidi M. Oxytocin deficiency impairs maternal skeletal remodeling. Biochem Biophys Res Commun. 2009 Oct 9; 388(1):161-6.
      View in: PubMed
    30. Lee JY, Taub PJ, Wang L, Clark A, Zhu LL, Maharam ER, Leong DJ, Ramcharan M, Li Z, Liu Z, Ma YZ, Sun L, Zaidi M, Majeska RJ, Sun HB. Identification of CITED2 as a negative regulator of fracture healing. Biochem Biophys Res Commun. 2009 Oct 2; 387(4):641-5.
      View in: PubMed
    31. Zaidi M, Blair HC, Iqbal J, Davies TF, Zhu LL, Zallone A, Sun L. New insights: elevated follicle-stimulating hormone and bone loss during the menopausal transition. Curr Rheumatol Rep. 2009 Jul; 11(3):191-5.
      View in: PubMed
    32. Iqbal J, Sun L, Zaidi M. Coupling bone degradation to formation. Nat Med. 2009 Jul; 15(7):729-31.
      View in: PubMed
    33. Zaidi M, Davies TF, Zallone A, Blair HC, Iqbal J, Moonga SS, Mechanick J, Sun L. Thyroid-stimulating hormone, thyroid hormones, and bone loss. Curr Osteoporos Rep. 2009 Jul; 7(2):47-52.
      View in: PubMed
    34. Iqbal J, Davies TF, Sun L, Abe E, Carpi A, Mechanick JI, Zaidi M. Skeletal morphofunctional considerations and the pituitary-thyroid axis. Front Biosci (Schol Ed). 2009; 1:92-107.
      View in: PubMed
    35. Sun L, Yang G, Zaidi M, Iqbal J. TNF-induced oscillations in combinatorial transcription factor binding. Biochem Biophys Res Commun. 2008 Jul 11; 371(4):912-6.
      View in: PubMed
    36. Sun L, Yang G, Zaidi M, Iqbal J. TNF-induced gene expression oscillates in time. Biochem Biophys Res Commun. 2008 Jul 11; 371(4):900-5.
      View in: PubMed
    37. Sun L, Vukicevic S, Baliram R, Yang G, Sendak R, McPherson J, Zhu LL, Iqbal J, Latif R, Natrajan A, Arabi A, Yamoah K, Moonga BS, Gabet Y, Davies TF, Bab I, Abe E, Sampath K, Zaidi M. Intermittent recombinant TSH injections prevent ovariectomy-induced bone loss. Proc Natl Acad Sci U S A. 2008 Mar 18; 105(11):4289-94.
      View in: PubMed
    38. Zeng T, Ren WZ, Sun LG. 4-Chloro-N-methyl-6-(morpholin-4-yl)-N-phenyl-1,3,5-triazin-2-amine. Acta Crystallogr Sect E Struct Rep Online. 2007; 64(Pt 1):o277.
      View in: PubMed
    39. Yang G, Zaidi M, Zhang W, Zhu LL, Li J, Iqbal J, Varbanov A, Gross G, Phipps R, Troen BR, Sun L. Functional grouping of osteoclast genes revealed through microarray analysis. Biochem Biophys Res Commun. 2008 Feb 8; 366(2):352-9.
      View in: PubMed
    40. Zaidi M, Blair HC, Iqbal J, Zhu LL, Kumar TR, Zallone A, Sun L. Proresorptive actions of FSH and bone loss. Ann N Y Acad Sci. 2007 Nov; 1116:376-82.
      View in: PubMed
    41. Abe E, Sun L, Mechanick J, Iqbal J, Yamoah K, Baliram R, Arabi A, Moonga BS, Davies TF, Zaidi M. Bone loss in thyroid disease: role of low TSH and high thyroid hormone. Ann N Y Acad Sci. 2007 Nov; 1116:383-91.
      View in: PubMed
    42. Sun L, Zhu LL, Zaidi N, Yang G, Moonga BS, Abe E, Iqbal J, Epstein S, Blair HC, Huang CL, Zaidi M. Cellular and molecular consequences of calcineurin A alpha gene deletion. Ann N Y Acad Sci. 2007 Nov; 1116:216-26.
      View in: PubMed
    43. Zaidi S, Zhu LL, Mali R, Iqbal J, Yang G, Zaidi M, Sun L. Regulation of FSH receptor promoter activation in the osteoclast. Biochem Biophys Res Commun. 2007 Oct 5; 361(4):910-5.
      View in: PubMed
    44. Zhu LL, Zaidi S, Peng Y, Zhou H, Moonga BS, Blesius A, Dupin-Roger I, Zaidi M, Sun L. Induction of a program gene expression during osteoblast differentiation with strontium ranelate. Biochem Biophys Res Commun. 2007 Apr 6; 355(2):307-11.
      View in: PubMed
    45. Iqbal J, Sun L, Kumar TR, Blair HC, Zaidi M. Follicle-stimulating hormone stimulates TNF production from immune cells to enhance osteoblast and osteoclast formation. Proc Natl Acad Sci U S A. 2006 Oct 3; 103(40):14925-30.
      View in: PubMed
    46. Sun L, Peng Y, Zaidi N, Zhu LL, Iqbal J, Yamoah K, Wang X, Liu P, Abe E, Moonga BS, Epstein S, Zaidi M. Evidence that calcineurin is required for the genesis of bone-resorbing osteoclasts. Am J Physiol Renal Physiol. 2007 Jan; 292(1):F285-91.
      View in: PubMed
    47. Hase H, Ando T, Eldeiry L, Brebene A, Peng Y, Liu L, Amano H, Davies TF, Sun L, Zaidi M, Abe E. TNFalpha mediates the skeletal effects of thyroid-stimulating hormone. Proc Natl Acad Sci U S A. 2006 Aug 22; 103(34):12849-54.
      View in: PubMed
    48. Iqbal J, Kumar K, Sun L, Zaidi M. Selective upregulation of the ADP-ribosyl cyclases CD38 and CD157 by TNF but not by RANK-L reveals differences in downstream signaling. Am J Physiol Renal Physiol. 2006 Sep; 291(3):F557-66.
      View in: PubMed
    49. Sun L, Peng Y, Sharrow AC, Iqbal J, Zhang Z, Papachristou DJ, Zaidi S, Zhu LL, Yaroslavskiy BB, Zhou H, Zallone A, Sairam MR, Kumar TR, Bo W, Braun J, Cardoso-Landa L, Schaffler MB, Moonga BS, Blair HC, Zaidi M. FSH directly regulates bone mass. Cell. 2006 Apr 21; 125(2):247-60.
      View in: PubMed
    50. Sun L, Davies TF, Blair HC, Abe E, Zaidi M. TSH and bone loss. Ann N Y Acad Sci. 2006 Apr; 1068:309-18.
      View in: PubMed
    51. Rajendren G, Zhou H, Moonga BS, Zaidi M, Sun L. Restoration of bone mass in hpg mouse by preoptic area grafting. Ann N Y Acad Sci. 2006 Apr; 1068:341-7.
      View in: PubMed
    52. Sun L, Iqbal J, Zaidi S, Zhu LL, Zhang X, Peng Y, Moonga BS, Zaidi M. Structure and functional regulation of the CD38 promoter. Biochem Biophys Res Commun. 2006 Mar 17; 341(3):804-9.
      View in: PubMed
    53. Sun L, Blair HC, Peng Y, Zaidi N, Adebanjo OA, Wu XB, Wu XY, Iqbal J, Epstein S, Abe E, Moonga BS, Zaidi M. Calcineurin regulates bone formation by the osteoblast. Proc Natl Acad Sci U S A. 2005 Nov 22; 102(47):17130-5.
      View in: PubMed
    54. Steuerwald AJ, Villeneuve JD, Sun L, Stenken JA. In vitro characterization of an in situ microdialysis sampling assay for elastase activity detection. J Pharm Biomed Anal. 2006 Mar 18; 40(5):1041-7.
      View in: PubMed
    55. Zhu LL, Zaidi S, Moonga BS, Troen BR, Sun L. RANK-L induces the expression of NFATc1, but not of NFkappaB subunits during osteoclast formation. Biochem Biophys Res Commun. 2005 Jan 7; 326(1):131-5.
      View in: PubMed
    56. Sun L, Stenken JA. Improving microdialysis extraction efficiency of lipophilic eicosanoids. J Pharm Biomed Anal. 2003 Dec 4; 33(5):1059-71.
      View in: PubMed
    57. Sun L, Stenken JA. Quantitation of nitric oxide-derived nitrite from activated macrophages using microdialysis sampling. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Nov 5; 796(2):327-38.
      View in: PubMed
    58. Sun L, Iqbal J, Dolgilevich S, Yuen T, Wu XB, Moonga BS, Adebanjo OA, Bevis PJ, Lund F, Huang CL, Blair HC, Abe E, Zaidi M. Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption. FASEB J. 2003 Mar; 17(3):369-75.
      View in: PubMed
    59. Dolgilevich S, Zaidi N, Song J, Abe E, Moonga BS, Sun L. Transduction of TAT fusion proteins into osteoclasts and osteoblasts. Biochem Biophys Res Commun. 2002 Dec 6; 299(3):505-9.
      View in: PubMed
    60. Sun L, Moonga BS, Lu M, Zaidi N, Iqbal J, Blair HC, Epstein S, Abe E, Troen BR, Huang CL, Zaidi M. Molecular cloning, expression, and function of osteoclastic calcineurin Aalpha. Am J Physiol Renal Physiol. 2003 Mar; 284(3):F575-83.
      View in: PubMed
    61. Moonga BS, Davidson R, Sun L, Adebanjo OA, Moser J, Abedin M, Zaidi N, Huang CL, Zaidi M. Identification and characterization of a sodium/calcium exchanger, NCX-1, in osteoclasts and its role in bone resorption. Biochem Biophys Res Commun. 2001 May 18; 283(4):770-5.
      View in: PubMed
    62. Stenken JA, Holunga DM, Decker SA, Sun L. Experimental and theoretical microdialysis studies of in situ metabolism. Anal Biochem. 2001 Mar; 290(2):314-23.
      View in: PubMed
    63. Adebanjo OA, Koval A, Moonga BS, Wu XB, Yao S, Bevis PJ, Kumegawa M, Zaidi M, Sun L. Molecular cloning, expression, and functional characterization of a novel member of the CD38 family of ADP-ribosyl cyclases. Biochem Biophys Res Commun. 2000 Jul 14; 273(3):884-9.
      View in: PubMed
    64. Adebanjo OA, Biswas G, Moonga BS, Anandatheerthavarada HK, Sun L, Bevis PJ, Sodam BR, Lai FA, Avadhani NG, Zaidi M. Novel biochemical and functional insights into nuclear Ca(2+) transport through IP(3)Rs and RyRs in osteoblasts. Am J Physiol Renal Physiol. 2000 May; 278(5):F784-91.
      View in: PubMed
    Sun's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts
    _
    Co-Authors
    _
    Similar People
    _
    Same Department
     
    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067