Keywords
Last Name
Institution

Adrian T. Ting

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentClinical Immunology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. T cell–derived inducible nitric oxide synthase switches off Th17 cell differentiation. J Exp Med. 2013 Jul 1; 210(7):1447-62.
      View in: PubMed
    2. Blackwell K, Zhang L, Workman LM, Ting AT, Iwai K, Habelhah H. Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed I?B kinase activation. Mol Cell Biol. 2013 May; 33(10):1901-15.
      View in: PubMed
    3. O'Donnell MA, Ting AT. NF?B and ubiquitination: partners in disarming RIPK1-mediated cell death. Immunol Res. 2012 Dec; 54(1-3):214-26.
      View in: PubMed
    4. Mayer L, Lira S, Ting A, Cortes P. Introduction to the special issue on Immunology at Mount Sinai. Immunol Res. 2012 Dec; 54(1-3):1-3.
      View in: PubMed
    5. O'Donnell MA, Hase H, Legarda D, Ting AT. NEMO inhibits programmed necrosis in an NF?B-independent manner by restraining RIP1. PLoS One. 2012; 7(7):e41238.
      View in: PubMed
    6. O'Donnell MA, Perez-Jimenez E, Oberst A, Ng A, Massoumi R, Xavier R, Green DR, Ting AT. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat Cell Biol. 2011 Dec; 13(12):1437-42.
      View in: PubMed
    7. Lu J, McEachern D, Sun H, Bai L, Peng Y, Qiu S, Miller R, Liao J, Yi H, Liu M, Bellail A, Hao C, Sun SY, Ting AT, Wang S. Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment. Mol Cancer Ther. 2011 May; 10(5):902-14.
      View in: PubMed
    8. O'Donnell MA, Ting AT. RIP1 comes back to life as a cell death regulator in TNFR1 signaling. FEBS J. 2011 Apr; 278(6):877-87.
      View in: PubMed
    9. Wu J, Zhang R, Torreggiani M, Ting A, Xiong H, Striker GE, Vlassara H, Zheng F. Induction of diabetes in aged C57B6 mice results in severe nephropathy: an association with oxidative stress, endoplasmic reticulum stress, and inflammation. Am J Pathol. 2010 May; 176(5):2163-76.
      View in: PubMed
    10. O'Donnell MA, Ting AT. Chronicles of a death foretold: dual sequential cell death checkpoints in TNF signaling. Cell Cycle. 2010 Mar 15; 9(6):1065-71.
      View in: PubMed
    11. Legarda-Addison D, Hase H, O'Donnell MA, Ting AT. NEMO/IKKgamma regulates an early NF-kappaB-independent cell-death checkpoint during TNF signaling. Cell Death Differ. 2009 Sep; 16(9):1279-88.
      View in: PubMed
    12. Friedman CS, O'Donnell MA, Legarda-Addison D, Ng A, Cárdenas WB, Yount JS, Moran TM, Basler CF, Komuro A, Horvath CM, Xavier R, Ting AT. The tumour suppressor CYLD is a negative regulator of RIG-I-mediated antiviral response. EMBO Rep. 2008 Sep; 9(9):930-6.
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    13. Yang J, Yang M, Htut TM, Ouyang X, Hanidu A, Li X, Sellati R, Jiang H, Zhang S, Li H, Zhao J, Ting AT, Mayer L, Unkeless JC, Labadia ME, Hodge M, Li J, Xiong H. Epstein-Barr virus-induced gene 3 negatively regulates IL-17, IL-22 and RORgamma t. Eur J Immunol. 2008 May; 38(5):1204-14.
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    14. Iyengar R, Diverse-Pierluissi MA, Jenkins SL, Chan AM, Devi LA, Sobie EA, Ting AT, Weinstein DC. Inquiry learning. Integrating content detail and critical reasoning by peer review. Science. 2008 Feb 29; 319(5867):1189-90.
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    15. Jenkins SL, Iyengar R, Diverse-Pierluissi MA, Chan AM, Devi LA, Sobie EA, Ting AT, Weinstein DC. Teaching resources. Using web-based discussion forums as a model of the peer-review process and a tool for assessment. Sci Signal. 2008; 1(9):tr2.
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    16. Legarda-Addison D, Ting AT. Negative regulation of TCR signaling by NF-kappaB2/p100. J Immunol. 2007 Jun 15; 178(12):7767-78.
      View in: PubMed
    17. O'Donnell MA, Legarda-Addison D, Skountzos P, Yeh WC, Ting AT. Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling. Curr Biol. 2007 Mar 6; 17(5):418-24.
      View in: PubMed
    18. Zhao Q, Yang M, Ting AT, Logothetis DE. PIP(2) regulates the ionic current of P2X receptors and P2X(7) receptor-mediated cell death. Channels (Austin). 2007 Jan-Feb; 1(1):46-55.
      View in: PubMed
    19. Yang M, Hase H, Legarda-Addison D, Varughese L, Seed B, Ting AT. B cell maturation antigen, the receptor for a proliferation-inducing ligand and B cell-activating factor of the TNF family, induces antigen presentation in B cells. J Immunol. 2005 Sep 1; 175(5):2814-24.
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    20. Zhang Y, Ting AT, Marcu KB, Bliska JB. Inhibition of MAPK and NF-kappa B pathways is necessary for rapid apoptosis in macrophages infected with Yersinia. J Immunol. 2005 Jun 15; 174(12):7939-49.
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    21. Ting A, Lichtenthaler S, Xavier R, Na SY, Rabizadeh S, Holmes T, Seed B. Large-scale screens for cDNAs with in vivo activity. Novartis Found Symp. 2005; 267:219-29; discussion 229-30.
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    22. Yang M, Liu N, Ting AT. [Study on a new IL-12 inducing gene NAP2]. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2003 Jul; 19(4):403-5.
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    23. Goodkin ML, Ting AT, Blaho JA. NF-kappaB is required for apoptosis prevention during herpes simplex virus type 1 infection. J Virol. 2003 Jul; 77(13):7261-80.
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    24. He KL, Ting AT. Essential role for IKKgamma/NEMO in TCR-induced IL-2 expression in Jurkat T cells. Eur J Immunol. 2003 Jul; 33(7):1917-24.
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    25. He KL, Ting AT. A20 inhibits tumor necrosis factor (TNF) alpha-induced apoptosis by disrupting recruitment of TRADD and RIP to the TNF receptor 1 complex in Jurkat T cells. Mol Cell Biol. 2002 Sep; 22(17):6034-45.
      View in: PubMed
    26. Colin AA, Sunil Rao J, Chen XC, Hunter JM, Hanrahan J, Hiatt P, Kattan M, Koumbourlis A, Mellins RB, Peavy HH, Platzker A, Ting A, Steinbach S, Wohl ME. Forced expiratory flow in uninfected infants and children born to HIV-infected mothers. Am J Respir Crit Care Med. 2001 Mar; 163(4):865-73.
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    27. Platzker AC, Colin AA, Chen XC, Hiatt P, Hunter J, Koumbourlis AC, Schluchter MD, Ting A, Wohl ME. Thoracoabdominal compression and respiratory system compliance in HIV-infected infants. Am J Respir Crit Care Med. 2000 May; 161(5):1567-71.
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    28. Izumi KM, Cahir McFarland ED, Ting AT, Riley EA, Seed B, Kieff ED. The Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activation. Mol Cell Biol. 1999 Aug; 19(8):5759-67.
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    29. Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature. 1998 Jan 1; 391(6662):82-6.
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    30. Ting A, Glick PL, Wilcox DT, Holm BA, Gil J, DiMaio M. Alveolar vascularization of the lung in a lamb model of congenital diaphragmatic hernia. Am J Respir Crit Care Med. 1998 Jan; 157(1):31-4.
      View in: PubMed
    31. Ting AT, Pimentel-Muiños FX, Seed B. RIP mediates tumor necrosis factor receptor 1 activation of NF-kappaB but not Fas/APO-1-initiated apoptosis. EMBO J. 1996 Nov 15; 15(22):6189-96.
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    32. Ting AT, Dick CJ, Schoon RA, Karnitz LM, Abraham RT, Leibson PJ. Interaction between lck and syk family tyrosine kinases in Fc gamma receptor-initiated activation of natural killer cells. J Biol Chem. 1995 Jul 7; 270(27):16415-21.
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    33. DiMaio MF, Ting A, Hsu MT, Gil J, Kattan M. Effect of zidovudine on human fetal lung development. Pediatr AIDS HIV Infect. 1995 Apr; 6(2):83-90.
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    34. Bonnema JD, Rivlin KA, Ting AT, Schoon RA, Abraham RT, Leibson PJ. Cytokine-enhanced NK cell-mediated cytotoxicity. Positive modulatory effects of IL-2 and IL-12 on stimulus-dependent granule exocytosis. J Immunol. 1994 Mar 1; 152(5):2098-104.
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    35. Ting AT, Karnitz LM, Schoon RA, Abraham RT, Leibson PJ. Fc gamma receptor activation induces the tyrosine phosphorylation of both phospholipase C (PLC)-gamma 1 and PLC-gamma 2 in natural killer cells. J Exp Med. 1992 Dec 1; 176(6):1751-5.
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    36. Ting AT, Schoon RA, Abraham RT, Leibson PJ. Interaction between protein kinase C-dependent and G protein-dependent pathways in the regulation of natural killer cell granule exocytosis. J Biol Chem. 1992 Nov 25; 267(33):23957-62.
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    37. Ting AT, Einspahr KJ, Abraham RT, Leibson PJ. Fc gamma receptor signal transduction in natural killer cells. Coupling to phospholipase C via a G protein-independent, but tyrosine kinase-dependent pathway. J Immunol. 1991 Nov 1; 147(9):3122-7.
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    38. Leiter EH, Christianson GJ, Serreze DV, Ting AT, Worthen SM. MHC antigen induction by interferon gamma on cultured mouse pancreatic beta cells and macrophages. Genetic analysis of strain differences and discovery of an "occult" class I-like antigen in NOD/Lt mice. J Exp Med. 1989 Oct 1; 170(4):1243-62.
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    39. Hoffman T, Lizzio EF, Ting A, Marshall LA, Bonvini E, Jennings MK. Release of arachidonic acid metabolites by human monocytes or lymphocytes: effect of treatment with interferon on stimulation by phorbol ester or calcium ionophore. Clin Immunol Immunopathol. 1987 Jul; 44(1):82-92.
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    40. Fuggle SV, Errasti P, Daar AS, Fabre JW, Ting A, Morris PJ. Localization of major histocompatibility complex (HLA-ABC and DR) antigens in 46 kidneys. Differences in HLA-DR staining of tubules among kidneys. Transplantation. 1983 Apr; 35(4):385-90.
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    41. Fuggle SV, Kirkley J, Ting A, Morris PJ. A monoclonal antibody recognizing HLA-DR2 on malignant and activated cells. Immunogenetics. 1983; 18(4):415-28.
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    42. Daar AS, Fuggle SV, Ting A, Fabre JW. Anomolous expression of HLA-DR antigens on human colorectal cancer cells. J Immunol. 1982 Aug; 129(2):447-9.
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    43. Hart DN, Fuggle SV, Williams KA, Fabre JW, Ting A, Morris PJ. Localization of HLA-ABC and DR antigens in human kidney. Transplantation. 1981 Jun; 31(6):428-33.
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    44. Ting A, Mickey MR, Terasaki PI. B-lymphocyte alloantigens in Caucasians. J Exp Med. 1976 Apr 1; 143(4):981-6.
      View in: PubMed
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067