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Last Name
Institution

Gabriele L. Gusella

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentNephrology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Liu Y, Rajagopal M, Lee K, Battini L, Flores D, Gusella GL, Pao AC, Rohatgi R. Prostaglandin E(2) mediates proliferation and chloride secretion in ADPKD cystic renal epithelia. Am J Physiol Renal Physiol. 2012 Nov 15; 303(10):F1425-34.
      View in: PubMed
    2. Rozenfeld R, Bushlin I, Gomes I, Tzavaras N, Gupta A, Neves S, Battini L, Gusella GL, Lachmann A, Ma'ayan A, Blitzer RD, Devi LA. Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons. PLoS One. 2012; 7(1):e29239.
      View in: PubMed
    3. Lee K, Battini L, Gusella GL. Cilium, centrosome and cell cycle regulation in polycystic kidney disease. Biochim Biophys Acta. 2011 Oct; 1812(10):1263-71.
      View in: PubMed
    4. Smaldone S, Olivieri J, Gusella GL, Moroncini G, Gabrielli A, Ramirez F. Ha-Ras stabilization mediates pro-fibrotic signals in dermal fibroblasts. Fibrogenesis Tissue Repair. 2011; 4(1):8.
      View in: PubMed
    5. Blitzer AL, Panagis L, Gusella GL, Danias J, Mlodzik M, Iomini C. Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):2819-24.
      View in: PubMed
    6. Flores D, Battini L, Gusella GL, Rohatgi R. Fluid shear stress induces renal epithelial gene expression through polycystin-2-dependent trafficking of extracellular regulated kinase. Nephron Physiol. 2011; 117(4):p27-36.
      View in: PubMed
    7. Mosoian A, Teixeira A, Burns CS, Sander LE, Gusella GL, He C, Blander JM, Klotman P, Klotman ME. Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction. Proc Natl Acad Sci U S A. 2010 Jun 1; 107(22):10178-83.
      View in: PubMed
    8. Battini L, Macip S, Fedorova E, Dikman S, Somlo S, Montagna C, Gusella GL. Loss of polycystin-1 causes centrosome amplification and genomic instability. Hum Mol Genet. 2008 Sep 15; 17(18):2819-33.
      View in: PubMed
    9. Rohatgi R, Battini L, Kim P, Israeli S, Wilson PD, Gusella GL, Satlin LM. Mechanoregulation of intracellular Ca2+ in human autosomal recessive polycystic kidney disease cyst-lining renal epithelial cells. Am J Physiol Renal Physiol. 2008 Apr; 294(4):F890-9.
      View in: PubMed
    10. Maffei M, Ghiotto F, Occhino M, Bono M, De Santanna A, Battini L, Gusella GL, Fais F, Bruno S, Ciccone E. Human cytomegalovirus regulates surface expression of the viral protein UL18 by means of two motifs present in the cytoplasmic tail. J Immunol. 2008 Jan 15; 180(2):969-79.
      View in: PubMed
    11. Li X, Burrow CR, Polgar K, Hyink DP, Gusella GL, Wilson PD. Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency. Biochim Biophys Acta. 2008 Jan; 1782(1):1-9.
      View in: PubMed
    12. Battini L, Fedorova E, Macip S, Li X, Wilson PD, Gusella GL. Stable knockdown of polycystin-1 confers integrin-alpha2beta1-mediated anoikis resistance. J Am Soc Nephrol. 2006 Nov; 17(11):3049-58.
      View in: PubMed
    13. Tan MC, Battini L, Tuyama AC, Macip S, Melendi GA, Horga MA, Gusella GL. Characterization of human metapneumovirus infection of myeloid dendritic cells. Virology. 2007 Jan 5; 357(1):1-9.
      View in: PubMed
    14. Fedorova E, Battini L, Prakash-Cheng A, Marras D, Gusella GL. Lentiviral gene delivery to CNS by spinal intrathecal administration to neonatal mice. J Gene Med. 2006 Apr; 8(4):414-24.
      View in: PubMed
    15. Ross MJ, Wosnitzer MS, Ross MD, Granelli B, Gusella GL, Husain M, Kaufman L, Vasievich M, D'Agati VD, Wilson PD, Klotman ME, Klotman PE. Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. J Am Soc Nephrol. 2006 Apr; 17(4):996-1004.
      View in: PubMed
    16. Li X, Hyink DP, Polgar K, Gusella GL, Wilson PD, Burrow CR. Protein kinase X activates ureteric bud branching morphogenesis in developing mouse metanephric kidney. J Am Soc Nephrol. 2005 Dec; 16(12):3543-52.
      View in: PubMed
    17. Polgar K, Burrow CR, Hyink DP, Fernandez H, Thornton K, Li X, Gusella GL, Wilson PD. Disruption of polycystin-1 function interferes with branching morphogenesis of the ureteric bud in developing mouse kidneys. Dev Biol. 2005 Oct 1; 286(1):16-30.
      View in: PubMed
    18. Horga MA, Macip S, Tuyama AC, Tan MC, Gusella GL. Human parainfluenza virus 3 neuraminidase activity contributes to dendritic cell maturation. Viral Immunol. 2005; 18(3):523-33.
      View in: PubMed
    19. Vargas J, Gusella GL, Najfeld V, Klotman ME, Cara A. Novel integrase-defective lentiviral episomal vectors for gene transfer. Hum Gene Ther. 2004 Apr; 15(4):361-72.
      View in: PubMed
    20. Husain M, Gusella GL, Klotman ME, Gelman IH, Ross MD, Schwartz EJ, Cara A, Klotman PE. HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. J Am Soc Nephrol. 2002 Jul; 13(7):1806-15.
      View in: PubMed
    21. Marras D, Bruggeman LA, Gao F, Tanji N, Mansukhani MM, Cara A, Ross MD, Gusella GL, Benson G, D'Agati VD, Hahn BH, Klotman ME, Klotman PE. Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. Nat Med. 2002 May; 8(5):522-6.
      View in: PubMed
    22. Gusella GL, Fedorova E, Hanss B, Marras D, Klotman ME, Klotman PE. Lentiviral gene transduction of kidney. Hum Gene Ther. 2002 Feb 10; 13(3):407-14.
      View in: PubMed
    23. Gusella GL, Fedorova E, Marras D, Klotman PE, Klotman ME. In vivo gene transfer to kidney by lentiviral vector. Kidney Int. 2002 Jan; 61(1 Suppl):S32-6.
      View in: PubMed
    24. Gillim L, Gusella GL, Vargas J, Marras D, Klotman ME, Cara A. Development of a novel screen for protease inhibitors. Clin Diagn Lab Immunol. 2001 Mar; 8(2):437-40.
      View in: PubMed
    25. Horga MA, Gusella GL, Greengard O, Poltoratskaia N, Porotto M, Moscona A. Mechanism of interference mediated by human parainfluenza virus type 3 infection. J Virol. 2000 Dec; 74(24):11792-9.
      View in: PubMed
    26. Cara A, Rybak SM, Newton DL, Crowley R, Rottschafer SE, Reitz MS, Gusella GL. Inhibition of HIV-1 replication by combined expression of gag dominant negative mutant and a human ribonuclease in a tightly controlled HIV-1 inducible vector. Gene Ther. 1998 Jan; 5(1):65-75.
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    27. Schwabe M, Deryugina EI, Bosco MC, Gusella GL, Reinisch W, Kung HF, Bourdon MA. IL-6 signals inhibition of cell adhesion in melanoma A375-C6. Anticancer Res. 1996 Nov-Dec; 16(6B):3363-70.
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    28. Musso T, Badolato R, Longo DL, Gusella GL, Varesio L. Leukemia inhibitory factor induces interleukin-8 and monocyte chemotactic and activating factor in human monocytes: differential regulation by interferon-gamma. Blood. 1995 Sep 1; 86(5):1961-7.
      View in: PubMed
    29. Espinoza-Delgado I, Bosco MC, Musso T, Gusella GL, Longo DL, Varesio L. Interleukin-2 and human monocyte activation. J Leukoc Biol. 1995 Jan; 57(1):13-9.
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    30. Gusella GL, Musso T, Rottschafer SE, Pulkki K, Varesio L. Potential requirement of a functional double-stranded RNA-dependent protein kinase (PKR) for the tumoricidal activation of macrophages by lipopolysaccharide or IFN-alpha beta, but not IFN-gamma. J Immunol. 1995 Jan 1; 154(1):345-54.
      View in: PubMed
    31. Musso T, Bosco MC, Longo DL, Espinoza-Delgado I, Sica A, Cox GW, Gusella GL, Forni G, Varesio L. LPS-inducible nuclear factor in human monocytes that binds the negative regulatory element of the HIV LTR. J Leukoc Biol. 1994 Jul; 56(1):21-6.
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    32. Bosco MC, Espinoza-Delgado I, Schwabe M, Gusella GL, Longo DL, Sugamura K, Varesio L. Regulation by interleukin-2 (IL-2) and interferon gamma of IL-2 receptor gamma chain gene expression in human monocytes. Blood. 1994 May 15; 83(10):2995-3002.
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    33. Musso T, Gusella GL, Brooks A, Longo DL, Varesio L. Interleukin-4 inhibits indoleamine 2,3-dioxygenase expression in human monocytes. Blood. 1994 Mar 1; 83(5):1408-11.
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    34. Bosco MC, Gusella GL, Espinoza-Delgado I, Longo DL, Varesio L. Interferon-gamma upregulates interleukin-8 gene expression in human monocytic cells by a posttranscriptional mechanism. Blood. 1994 Jan 15; 83(2):537-42.
      View in: PubMed
    35. Gusella GL, Musso T, Bosco MC, Espinoza-Delgado I, Matsushima K, Varesio L. IL-2 up-regulates but IFN-gamma suppresses IL-8 expression in human monocytes. J Immunol. 1993 Sep 1; 151(5):2725-32.
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    36. Muegge K, Vila M, Gusella GL, Musso T, Herrlich P, Stein B, Durum SK. Interleukin 1 induction of the c-jun promoter. Proc Natl Acad Sci U S A. 1993 Aug 1; 90(15):7054-8.
      View in: PubMed
    37. Bosco MC, Musso T, Gusella GL, Giovarelli M, Forni M, Soleti A, Masuelli L, Modesti A, Forni G, Varesio L. Selective transformation of host lymphocytes in vivo by retrovirus-producing macrophages. J Immunol. 1993 Jan 1; 150(1):278-89.
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    38. Espinoza-Delgado I, Longo DL, Gusella GL, Varesio L. Regulation of IL-2 receptor subunit genes in human monocytes. Differential effects of IL-2 and IFN-gamma. J Immunol. 1992 Nov 1; 149(9):2961-8.
      View in: PubMed
    39. Musso T, Espinoza-Delgado I, Pulkki K, Gusella GL, Longo DL, Varesio L. IL-2 induces IL-6 production in human monocytes. J Immunol. 1992 Feb 1; 148(3):795-800.
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    40. Varesio L, Radzioch D, Bottazzi B, Gusella GL. Ribosomal RNA metabolism in macrophages. Curr Top Microbiol Immunol. 1992; 181:209-37.
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    41. Carbone A, Gusella GL, Radzioch D, Varesio L. Human Harvey-ras is biochemically different from Kirsten- or N-ras. Oncogene. 1991 May; 6(5):731-7.
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    42. Mukaida N, Zachariae CC, Gusella GL, Matsushima K. Dexamethasone inhibits the induction of monocyte chemotactic-activating factor production by IL-1 or tumor necrosis factor. J Immunol. 1991 Feb 15; 146(4):1212-5.
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    43. Musso T, Espinoza-Delgado I, Pulkki K, Gusella GL, Longo DL, Varesio L. Transforming growth factor beta downregulates interleukin-1 (IL-1)-induced IL-6 production by human monocytes. Blood. 1990 Dec 15; 76(12):2466-9.
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    44. Espinoza-Delgado I, Longo DL, Gusella GL, Varesio L. IL-2 enhances c-fms expression in human monocytes. J Immunol. 1990 Aug 15; 145(4):1137-43.
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    45. Gusella GL, Ayroldi E, Espinoza-Delgado I, Varesio L. Lipopolysaccharide, but not IFN-gamma, down-regulates c-fms mRNA proto-oncogene expression in murine macrophages. J Immunol. 1990 May 1; 144(9):3574-80.
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    46. Faltynek CR, Princler GL, Gusella GL, Varesio L, Radzioch D. A functional protein kinase C is required for induction of 2-5A synthetase by recombinant interferon-alpha A in Daudi cells. J Biol Chem. 1989 Aug 25; 264(24):14305-11.
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    47. Carbone A, Gusella GL, Radzioch D, Varesio L. Harvey-ras, but not Kirsten or N-ras, inhibits the induction of C-fos expression. Ann N Y Acad Sci. 1988; 551:361-2.
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067