Keywords
Last Name
Institution

Savio L.C. Woo

TitlePROFESSOR
InstitutionMount Sinai
DepartmentHematology and Medical Oncology
Address
    Other Positions
    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentOncological Sciences

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentGenetics and Genomic Sciences


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Eisenstein S, Coakley BA, Briley-Saebo K, Ma G, Chen HM, Meseck M, Ward S, Divino C, Woo S, Chen SH, Pan PY. Myeloid-derived suppressor cells as a vehicle for tumor-specific oncolytic viral therapy. Cancer Res. 2013 Aug 15; 73(16):5003-15.
      View in: PubMed
    2. Yamaki M, Shinozaki K, Sakaguchi T, Meseck M, Ebert O, Ohdan H, Woo SL. The potential of recombinant vesicular stomatitis virus-mediated virotherapy against metastatic colon cancer. Int J Mol Med. 2013 Feb; 31(2):299-306.
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    3. Ausubel LJ, Meseck M, Derecho I, Lopez P, Knoblauch C, McMahon R, Anderson J, Dunphy N, Quezada V, Khan R, Huang P, Dang W, Luo M, Hsu D, Woo SL, Couture L. Current good manufacturing practice production of an oncolytic recombinant vesicular stomatitis viral vector for cancer treatment. Hum Gene Ther. 2011 Apr; 22(4):489-97.
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    4. Cormode DP, Skajaa GO, Delshad A, Parker N, Jarzyna PA, Calcagno C, Galper MW, Skajaa T, Briley-Saebo KC, Bell HM, Gordon RE, Fayad ZA, Woo SL, Mulder WJ. A versatile and tunable coating strategy allows control of nanocrystal delivery to cell types in the liver. Bioconjug Chem. 2011 Mar 16; 22(3):353-61.
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    5. Meseck M, Huang T, Ma G, Wang G, Chen SH, Woo SL. A functional recombinant human 4-1BB ligand for immune costimulatory therapy of cancer. J Immunother. 2011 Mar; 34(2):175-82.
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    6. Liang R, Fisher M, Yang G, Hall C, Woo SL. Alpha1,3-galactosyltransferase knockout does not alter the properties of porcine extracellular matrix bioscaffolds. Acta Biomater. 2011 Apr; 7(4):1719-27.
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    7. Kubo T, Shimose S, Matsuo T, Fujimori J, Sakaguchi T, Yamaki M, Shinozaki K, Woo SL, Ochi M. Oncolytic vesicular stomatitis virus administered by isolated limb perfusion suppresses osteosarcoma growth. J Orthop Res. 2011 May; 29(5):795-800.
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    8. Woo SL. Retraction for Chen et al., Complete and persistent phenotypic correction of phenylketonuria in mice by site-specific genome integration of murine phenylalanine hydroxylase cDNA. Proc Natl Acad Sci U S A. 2010 Aug 10; 107(32):14514.
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    9. Li Z, Fallon J, Mandeli J, Wetmur J, Woo SL. Retraction: A genetically enhanced anaerobic bacterium for oncopathic therapy of pancreatic cancer. J Natl Cancer Inst. 2010 Feb 24; 102(4):283.
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    10. Li Z, Fallon J, Mandeli J, Wetmur J, Woo SL. The oncopathic potency of Clostridium perfringens is independent of its alpha-toxin gene. Hum Gene Ther. 2009 Jul; 20(7):751-8.
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    11. Woo SL. Tissue engineering: use of scaffolds for ligament and tendon healing and regeneration. Knee Surg Sports Traumatol Arthrosc. 2009 Jun; 17(6):559-60.
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    12. Brem H, Kodra A, Golinko MS, Entero H, Stojadinovic O, Wang VM, Sheahan CM, Weinberg AD, Woo SL, Ehrlich HP, Tomic-Canic M. Mechanism of sustained release of vascular endothelial growth factor in accelerating experimental diabetic healing. J Invest Dermatol. 2009 Sep; 129(9):2275-87.
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    13. Woo SL. From "Gene Therapy" to "Gene and Cell Therapy": Why? Mol Ther. 2008 Dec; 16(12):1899-900.
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    14. Altomonte J, Wu L, Meseck M, Chen L, Ebert O, Garcia-Sastre A, Fallon J, Mandeli J, Woo SL. Enhanced oncolytic potency of vesicular stomatitis virus through vector-mediated inhibition of NK and NKT cells. Cancer Gene Ther. 2009 Mar; 16(3):266-78.
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    15. Li Z, Fallon J, Mandeli J, Wetmur J, Woo SL. A genetically enhanced anaerobic bacterium for oncopathic therapy of pancreatic cancer. J Natl Cancer Inst. 2008 Oct 1; 100(19):1389-400.
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    16. Almarza AJ, Augustine SM, Woo SL. Changes in gene expression of matrix constituents with respect to passage of ligament and tendon fibroblasts. Ann Biomed Eng. 2008 Dec; 36(12):1927-33.
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    17. Almarza AJ, Yang G, Woo SL, Nguyen T, Abramowitch SD. Positive changes in bone marrow-derived cells in response to culture on an aligned bioscaffold. Tissue Eng Part A. 2008 Sep; 14(9):1489-95.
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    18. Liang R, Woo SL, Nguyen TD, Liu PC, Almarza A. Effects of a bioscaffold on collagen fibrillogenesis in healing medial collateral ligament in rabbits. J Orthop Res. 2008 Aug; 26(8):1098-104.
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    19. Wu L, Huang TG, Meseck M, Altomonte J, Ebert O, Shinozaki K, García-Sastre A, Fallon J, Mandeli J, Woo SL. rVSV(M Delta 51)-M3 is an effective and safe oncolytic virus for cancer therapy. Hum Gene Ther. 2008 Jun; 19(6):635-47.
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    20. Chen L, Woo SL. Site-specific transgene integration in the human genome catalyzed by phiBT1 phage integrase. Hum Gene Ther. 2008 Feb; 19(2):143-51.
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    21. Sung CK, Choi B, Wanna G, Genden EM, Woo SL, Shin EJ. Combined VSV oncolytic virus and chemotherapy for squamous cell carcinoma. Laryngoscope. 2008 Feb; 118(2):237-42.
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    22. Altomonte J, Wu L, Chen L, Meseck M, Ebert O, García-Sastre A, Fallon J, Woo SL. Exponential enhancement of oncolytic vesicular stomatitis virus potency by vector-mediated suppression of inflammatory responses in vivo. Mol Ther. 2008 Jan; 16(1):146-53.
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    23. Chen L, Huang TG, Meseck M, Mandeli J, Fallon J, Woo SL. Rejection of metastatic 4T1 breast cancer by attenuation of Treg cells in combination with immune stimulation. Mol Ther. 2007 Dec; 15(12):2194-202.
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    24. Vigil A, Park MS, Martinez O, Chua MA, Xiao S, Cros JF, Martínez-Sobrido L, Woo SL, García-Sastre A. Use of reverse genetics to enhance the oncolytic properties of Newcastle disease virus. Cancer Res. 2007 Sep 1; 67(17):8285-92.
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    25. Chen L, Woo SL. Correction in female PKU mice by repeated administration of mPAH cDNA using phiBT1 integration system. Mol Ther. 2007 Oct; 15(10):1789-95.
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    26. Gilbert TW, Stewart-Akers AM, Sydeski J, Nguyen TD, Badylak SF, Woo SL. Gene expression by fibroblasts seeded on small intestinal submucosa and subjected to cyclic stretching. Tissue Eng. 2007 Jun; 13(6):1313-23.
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    27. Shin EJ, Chang JI, Choi B, Wanna G, Ebert O, Genden EM, Woo SL. Fusogenic vesicular stomatitis virus for the treatment of head and neck squamous carcinomas. Otolaryngol Head Neck Surg. 2007 May; 136(5):811-7.
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    28. Chen L, Thung SN, Woo SL. Metabolic basis of sexual dimorphism in PKU mice after genome-targeted PAH gene therapy. Mol Ther. 2007 Jun; 15(6):1079-85.
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    29. Shin EJ, Wanna GB, Choi B, Aguila D, Ebert O, Genden EM, Woo SL. Interleukin-12 expression enhances vesicular stomatitis virus oncolytic therapy in murine squamous cell carcinoma. Laryngoscope. 2007 Feb; 117(2):210-4.
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    30. Woo SL, Skarlatos SI, Joyce MM, Croxton TL, Qasba P. Critical resources for gene therapy in Heart, Lung, and Blood Diseases Working Group. Mol Ther. 2006 Apr; 13(4):641-3.
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    31. Shinozaki K, Suominen E, Carrick F, Sauter B, Kähäri VM, Lieber A, Woo SL, Savontaus M. Efficient infection of tumor endothelial cells by a capsid-modified adenovirus. Gene Ther. 2006 Jan; 13(1):52-9.
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    32. Shinozaki K, Ebert O, Suriawinata A, Thung SN, Woo SL. Prophylactic alpha interferon treatment increases the therapeutic index of oncolytic vesicular stomatitis virus virotherapy for advanced hepatocellular carcinoma in immune-competent rats. J Virol. 2005 Nov; 79(21):13705-13.
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    33. Chen L, Woo SL. Complete and persistent phenotypic correction of phenylketonuria in mice by site-specific genome integration of murine phenylalanine hydroxylase cDNA. Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15581-6.
      View in: PubMed
    34. Xu DP, Sauter BV, Huang TG, Meseck M, Woo SL, Chen SH. The systemic administration of Ig-4-1BB ligand in combination with IL-12 gene transfer eradicates hepatic colon carcinoma. Gene Ther. 2005 Oct; 12(20):1526-33.
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    35. Jia F, Shimomura T, Niyibizi C, Woo SL. Downregulation of human type III collagen gene expression by antisense oligodeoxynucleotide. Tissue Eng. 2005 Sep-Oct; 11(9-10):1429-35.
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    36. Shinozaki K, Ebert O, Woo SL. Treatment of multi-focal colorectal carcinoma metastatic to the liver of immune-competent and syngeneic rats by hepatic artery infusion of oncolytic vesicular stomatitis virus. Int J Cancer. 2005 Apr 20; 114(4):659-64.
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    37. Ebert O, Harbaran S, Shinozaki K, Woo SL. Systemic therapy of experimental breast cancer metastases by mutant vesicular stomatitis virus in immune-competent mice. Cancer Gene Ther. 2005 Apr; 12(4):350-8.
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    38. Shinozaki K, Ebert O, Woo SL. Eradication of advanced hepatocellular carcinoma in rats via repeated hepatic arterial infusions of recombinant VSV. Hepatology. 2005 Jan; 41(1):196-203.
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    39. Ebert O, Shinozaki K, Kournioti C, Park MS, García-Sastre A, Woo SL. Syncytia induction enhances the oncolytic potential of vesicular stomatitis virus in virotherapy for cancer. Cancer Res. 2004 May 1; 64(9):3265-70.
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    40. Kubo A, Shinozaki K, Shannon JM, Kouskoff V, Kennedy M, Woo S, Fehling HJ, Keller G. Development of definitive endoderm from embryonic stem cells in culture. Development. 2004 Apr; 131(7):1651-62.
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    41. Shinozaki K, Ebert O, Kournioti C, Tai YS, Woo SL. Oncolysis of multifocal hepatocellular carcinoma in the rat liver by hepatic artery infusion of vesicular stomatitis virus. Mol Ther. 2004 Mar; 9(3):368-76.
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    42. Song Y, Debski RE, Musahl V, Thomas M, Woo SL. A three-dimensional finite element model of the human anterior cruciate ligament: a computational analysis with experimental validation. J Biomech. 2004 Mar; 37(3):383-90.
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    43. Woo SL, Jia F, Zou L, Gabriel MT. Functional tissue engineering for ligament healing: potential of antisense gene therapy. Ann Biomed Eng. 2004 Mar; 32(3):342-51.
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    44. Li Z, Yang G, Khan M, Stone D, Woo SL, Wang JH. Inflammatory response of human tendon fibroblasts to cyclic mechanical stretching. Am J Sports Med. 2004 Mar; 32(2):435-40.
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    45. Musahl V, Abramowitch SD, Gilbert TW, Tsuda E, Wang JH, Badylak SF, Woo SL. The use of porcine small intestinal submucosa to enhance the healing of the medial collateral ligament--a functional tissue engineering study in rabbits. J Orthop Res. 2004 Jan; 22(1):214-20.
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    46. Huang TG, Ebert O, Shinozaki K, García-Sastre A, Woo SL. Oncolysis of hepatic metastasis of colorectal cancer by recombinant vesicular stomatitis virus in immune-competent mice. Mol Ther. 2003 Sep; 8(3):434-40.
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    47. Huang TG, Savontaus MJ, Shinozaki K, Sauter BV, Woo SL. Telomerase-dependent oncolytic adenovirus for cancer treatment. Gene Ther. 2003 Aug; 10(15):1241-7.
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    48. Ebert O, Shinozaki K, Huang TG, Savontaus MJ, García-Sastre A, Woo SL. Oncolytic vesicular stomatitis virus for treatment of orthotopic hepatocellular carcinoma in immune-competent rats. Cancer Res. 2003 Jul 1; 63(13):3605-11.
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    49. Musahl V, Abramowitch SD, Gabriel MT, Debski RE, Hertel P, Fu FH, Woo SL. Tensile properties of an anterior cruciate ligament graft after bone-patellar tendon-bone press-fit fixation. Knee Surg Sports Traumatol Arthrosc. 2003 Mar; 11(2):68-74.
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    50. Wang JH, Jia F, Gilbert TW, Woo SL. Cell orientation determines the alignment of cell-produced collagenous matrix. J Biomech. 2003 Jan; 36(1):97-102.
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    51. Debski RE, Fenwick JA, Vangura A, Fu FH, Woo SL, Rodosky MW. Effect of arthroscopic procedures on the acromioclavicular joint. Clin Orthop Relat Res. 2003 Jan; (406):89-96.
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    52. Shimomura T, Jia F, Niyibizi C, Woo SL. Antisense oligonucleotides reduce synthesis of procollagen alpha1 (V) chain in human patellar tendon fibroblasts: potential application in healing ligaments and tendons. Connect Tissue Res. 2003; 44(3-4):167-72.
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    53. Wang JH, Jia F, Yang G, Yang S, Campbell BH, Stone D, Woo SL. Cyclic mechanical stretching of human tendon fibroblasts increases the production of prostaglandin E2 and levels of cyclooxygenase expression: a novel in vitro model study. Connect Tissue Res. 2003; 44(3-4):128-33.
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    54. Bhoumik A, Huang TG, Ivanov V, Gangi L, Qiao RF, Woo SL, Chen SH, Ronai Z. An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis. J Clin Invest. 2002 Sep; 110(5):643-50.
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    55. Morral N, McEvoy R, Dong H, Meseck M, Altomonte J, Thung S, Woo SL. Adenovirus-mediated expression of glucokinase in the liver as an adjuvant treatment for type 1 diabetes. Hum Gene Ther. 2002 Sep 1; 13(13):1561-70.
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    56. Woo S. Clinical gene transfer: adverse event reporting fully harmonized. Mol Ther. 2002 Aug; 6(2):140.
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    57. Watanabe N, Woo SL, Papageorgiou C, Celechovsky C, Takai S. Fate of donor bone marrow cells in medial collateral ligament after simulated autologous transplantation. Microsc Res Tech. 2002 Jul 1; 58(1):39-44.
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    58. Hildebrand KA, Jia F, Woo SL. Response of donor and recipient cells after transplantation of cells to the ligament and tendon. Microsc Res Tech. 2002 Jul 1; 58(1):34-8.
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    59. Savontaus MJ, Sauter BV, Huang TG, Woo SL. Transcriptional targeting of conditionally replicating adenovirus to dividing endothelial cells. Gene Ther. 2002 Jul; 9(14):972-9.
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    60. Martinek V, Latterman C, Usas A, Abramowitch S, Woo SL, Fu FH, Huard J. Enhancement of tendon-bone integration of anterior cruciate ligament grafts with bone morphogenetic protein-2 gene transfer: a histological and biomechanical study. J Bone Joint Surg Am. 2002 Jul; 84-A(7):1123-31.
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    61. Bonadio J, Woo SL, High K, Ghivizzani S, Schaffer D. Genetic approaches to tissue engineering: breakout session summary. Ann N Y Acad Sci. 2002 Jun; 961:71-2.
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    62. Woo SL. Gene transfer in tissue regeneration and reparative medicine. Ann N Y Acad Sci. 2002 Jun; 961:61-2.
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    63. Sung MW, Chen SH, Thung SN, Zhang DY, Huang TG, Mandeli JP, Woo SL. Intratumoral delivery of adenovirus-mediated interleukin-12 gene in mice with metastatic cancer in the liver. Hum Gene Ther. 2002 Apr 10; 13(6):731-43.
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    64. Attur MG, Dave MN, Leung MY, Cipolletta C, Meseck M, Woo SL, Amin AR. Functional genomic analysis of type II IL-1beta decoy receptor: potential for gene therapy in human arthritis and inflammation. J Immunol. 2002 Feb 15; 168(4):2001-10.
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    65. Qiao J, Doubrovin M, Sauter BV, Huang Y, Guo ZS, Balatoni J, Akhurst T, Blasberg RG, Tjuvajev JG, Chen SH, Woo SL. Tumor-specific transcriptional targeting of suicide gene therapy. Gene Ther. 2002 Feb; 9(3):168-75.
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    66. Dong H, Altomonte J, Morral N, Meseck M, Thung SN, Woo SL. Basal insulin gene expression significantly improves conventional insulin therapy in type 1 diabetic rats. Diabetes. 2002 Jan; 51(1):130-8.
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    67. Dong H, Woo SL. Hepatic insulin production for type 1 diabetes. Trends Endocrinol Metab. 2001 Dec; 12(10):441-6.
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    68. Vlachaki MT, Chhikara M, Aguilar L, Zhu X, Chiu KJ, Woo S, Teh BS, Thompson TC, Butler EB, Aguilar-Cordova E. Enhanced therapeutic effect of multiple injections of HSV-TK + GCV gene therapy in combination with ionizing radiation in a mouse mammary tumor model. Int J Radiat Oncol Biol Phys. 2001 Nov 15; 51(4):1008-17.
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    69. Waugh JM, Li-Hawkins J, Yuksel E, Cifra PN, Amabile PG, Hilfiker PR, Geske RS, Kuo MD, Thomas JW, Dake MD, Woo SL. Therapeutic elastase inhibition by alpha-1-antitrypsin gene transfer limits neointima formation in normal rabbits. J Vasc Interv Radiol. 2001 Oct; 12(10):1203-9.
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    70. Sung MW, Yeh HC, Thung SN, Schwartz ME, Mandeli JP, Chen SH, Woo SL. Intratumoral adenovirus-mediated suicide gene transfer for hepatic metastases from colorectal adenocarcinoma: results of a phase I clinical trial. Mol Ther. 2001 Sep; 4(3):182-91.
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    71. Woo SL. Clinical gene transfer: education is the key. Mol Ther. 2001 Aug; 4(2):92.
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    72. Dong H, Morral N, McEvoy R, Meseck M, Thung SN, Woo SL. Hepatic insulin expression improves glycemic control in type 1 diabetic rats. Diabetes Res Clin Pract. 2001 Jun; 52(3):153-63.
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    73. Kwong YL, Chen SH, Woo SL. Methods for cancer gene therapy. Curr Protoc Hum Genet. 2001 May; Chapter 13:Unit 13.5.
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    74. Chen R, Meseck ML, Woo SL. Auto-regulated hepatic insulin gene expression in type 1 diabetic rats. Mol Ther. 2001 Apr; 3(4):584-90.
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    75. Chhikara M, Huang H, Vlachaki MT, Zhu X, Teh B, Chiu KJ, Woo S, Berner B, Smith EO, Oberg KC, Aguilar LK, Thompson TC, Butler EB, Aguilar-Cordova E. Enhanced therapeutic effect of HSV-tk+GCV gene therapy and ionizing radiation for prostate cancer. Mol Ther. 2001 Apr; 3(4):536-42.
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    76. Chen R, Meseck M, McEvoy RC, Woo SL. Glucose-stimulated and self-limiting insulin production by glucose 6-phosphatase promoter driven insulin expression in hepatoma cells. Gene Ther. 2000 Nov; 7(21):1802-9.
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    77. Woo SL. Gene therapy researchers react to field's pitfalls and promises. FDA Consum. 2000 Sep-Oct; 34(5):40.
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    78. Chen SH, Pham-Nguyen KB, Martinet O, Huang Y, Yang W, Thung SN, Chen L, Mittler R, Woo SL. Rejection of disseminated metastases of colon carcinoma by synergism of IL-12 gene therapy and 4-1BB costimulation. Mol Ther. 2000 Jul; 2(1):39-46.
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    79. Woo SL. Policy of the American Society of Gene Therapy on financial conflict ofinterest in clinical research. Mol Ther. 2000 May; 1(5 Pt 1):383-4.
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    80. Sauter BV, Martinet O, Zhang WJ, Mandeli J, Woo SL. Adenovirus-mediated gene transfer of endostatin in vivo results in high level of transgene expression and inhibition of tumor growth and metastases. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4802-7.
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    81. Hassan W, Sanford MA, Woo SL, Chen SH, Hall SJ. Prospects for herpes-simplex-virus thymidine-kinase and cytokine gene transduction as immunomodulatory gene therapy for prostate cancer. World J Urol. 2000 Apr; 18(2):130-5.
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    82. Divino CM, Chen SH, Yang W, Thung S, Brower ST, Woo SL. Anti-tumor immunity induced by interleukin-12 gene therapy in a metastatic model of breast cancer is mediated by natural killer cells. Breast Cancer Res Treat. 2000 Mar; 60(2):129-34.
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    83. Block A, Freund CT, Chen SH, Nguyen KP, Finegold M, Windler E, Woo SL. Gene therapy of metastatic colon carcinoma: regression of multiple hepatic metastases by adenoviral expression of bacterial cytosine deaminase. Cancer Gene Ther. 2000 Mar; 7(3):438-45.
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    84. Trask TW, Trask RP, Aguilar-Cordova E, Shine HD, Wyde PR, Goodman JC, Hamilton WJ, Rojas-Martinez A, Chen SH, Woo SL, Grossman RG. Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors. Mol Ther. 2000 Feb; 1(2):195-203.
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    85. Woo SL. Policy statement of the American Society of Gene Therapy on reporting of patient adverse events in gene therapy trials. Mol Ther. 2000 Jan; 1(1):7-8.
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    86. Enns GM, Martinez DR, Kuzmin AI, Koch R, Wakeem CK, Woo SL, Eisensmith RC, Packman S. Molecular correlations in phenylketonuria: mutation patterns and corresponding biochemical and clinical phenotypes in a heterogeneous California population. Pediatr Res. 1999 Nov; 46(5):594-602.
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    87. Wu Y, Liu J, Woo S, Finegold MJ, Brandt ML. Prenatal orogastric gene delivery results in transduction of the small bowel in the fetal rabbit. Fetal Diagn Ther. 1999 Nov-Dec; 14(6):323-7.
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    88. Tjuvajev JG, Chen SH, Joshi A, Joshi R, Guo ZS, Balatoni J, Ballon D, Koutcher J, Finn R, Woo SL, Blasberg RG. Imaging adenoviral-mediated herpes virus thymidine kinase gene transfer and expression in vivo. Cancer Res. 1999 Oct 15; 59(20):5186-93.
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    89. Woo SL, Hildebrand K, Watanabe N, Fenwick JA, Papageorgiou CD, Wang JH. Tissue engineering of ligament and tendon healing. Clin Orthop Relat Res. 1999 Oct; (367 Suppl):S312-23.
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    90. Shirakawa T, Gardner TA, Ko SC, Bander N, Woo S, Gotoh A, Kamidono S, Chung LW, Kao C. Cytotoxicity of adenoviral-mediated cytosine deaminase plus 5-fluorocytosine gene therapy is superior to thymidine kinase plus acyclovir in a human renal cell carcinoma model. J Urol. 1999 Sep; 162(3 Pt 1):949-54.
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    91. Qiao J, Chen SH, Pham-Nguyen KB, Mandeli J, Woo SL. Construction and characterization of a recombinant adenoviral vector expressing human interleukin-12. Cancer Gene Ther. 1999 Jul-Aug; 6(4):373-9.
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    92. Kulling D, Vournakis JN, Woo S, Demcheva MV, Tagge DU, Rios G, Finkielsztein S, Hawes RH. Endoscopic injection of bleeding esophageal varices with a poly-N-acetyl glucosamine gel formulation in the canine portal hypertension model. Gastrointest Endosc. 1999 Jun; 49(6):764-71.
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    93. Pham-Nguyen KB, Yang W, Saxena R, Thung SN, Woo SL, Chen SH. Role of NK and T cells in IL-12-induced anti-tumor response against hepatic colon carcinoma. Int J Cancer. 1999 May 31; 81(5):813-9.
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    94. Herman JR, Adler HL, Aguilar-Cordova E, Rojas-Martinez A, Woo S, Timme TL, Wheeler TM, Thompson TC, Scardino PT. In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial. Hum Gene Ther. 1999 May 1; 10(7):1239-49.
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    95. Zeilinger S, Galhaup C, Payer K, Woo SL, Mach RL, Fekete C, Lorito M, Kubicek CP. Chitinase gene expression during mycoparasitic interaction of Trichoderma harzianum with its host. Fungal Genet Biol. 1999 Mar; 26(2):131-40.
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    96. O'Malley BW, Li D, Buckner A, Duan L, Woo SL, Pardoll DM. Limitations of adenovirus-mediated interleukin-2 gene therapy for oral cancer. Laryngoscope. 1999 Mar; 109(3):389-95.
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    97. Waugh JM, Kattash M, Li J, Yuksel E, Kuo MD, Lussier M, Weinfeld AB, Saxena R, Rabinovsky ED, Thung S, Woo SL, Shenaq SM. Gene therapy to promote thromboresistance: local overexpression of tissue plasminogen activator to prevent arterial thrombosis in an in vivo rabbit model. Proc Natl Acad Sci U S A. 1999 Feb 2; 96(3):1065-70.
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    98. Tong X, Engehausen DG, Freund CT, Agoulnik I, Oehler MK, Kim TE, Hasenburg A, Guo Z, Contant CF, Woo SL, Kieback DG. Comparison of long-term survival of cytomegalovirus promotre versus Rous Sarcoma virus promoter-driven thymidine kinase gene therapy in nude mice bearing human ovarian cancer. Hybridoma. 1999 Feb; 18(1):93-7.
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    99. Effat L, Kuzmin A, Kasem N, Meguid NA, Kotb S, Eisensmith RC, Temtamy SA, Rushdi S, Woo S, el-Awady M. Haplotypes and mutations of the PAH locus in Egyptian families with PKU. Eur J Hum Genet. 1999 Feb-Mar; 7(2):259-62.
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    100. Linden RM, Woo SL. AAVant-garde gene therapy. Nat Med. 1999 Jan; 5(1):21-2.
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    101. Hildebrand KA, Deie M, Allen CR, Smith DW, Georgescu HI, Evans CH, Robbins PD, Woo SL. Early expression of marker genes in the rabbit medial collateral and anterior cruciate ligaments: the use of different viral vectors and the effects of injury. J Orthop Res. 1999 Jan; 17(1):37-42.
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    102. Waugh JM, Yuksel E, Li J, Kuo MD, Kattash M, Saxena R, Geske R, Thung SN, Shenaq SM, Woo SL. Local overexpression of thrombomodulin for in vivo prevention of arterial thrombosis in a rabbit model. Circ Res. 1999 Jan 8-22; 84(1):84-92.
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    103. Hall SJ, Mutchnik SE, Yang G, Timme TL, Nasu Y, Bangma CH, Woo SL, Shaker M, Thompson TC. Cooperative therapeutic effects of androgen ablation and adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy in experimental prostate cancer. Cancer Gene Ther. 1999 Jan-Feb; 6(1):54-63.
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    104. Rojas-Martinez A, Wyde PR, Montgomery CA, Chen SH, Woo SL, Aguilar-Cordova E. Distribution, persistency, toxicity, and lack of replication of an E1A-deficient adenoviral vector after intracardiac delivery in the cotton rat. Cancer Gene Ther. 1998 Nov-Dec; 5(6):365-70.
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    105. Tong X, Shine DH, Agoulnik I, Freund CT, Hasenburg A, Aguilar-Cordova E, Woo SL, Kieback DG. Adenovirus mediated thymidine kinase gene therapy may enhance sensitivity of ovarian cancer cells to chemotherapeutic agents. Anticancer Res. 1998 Sep-Oct; 18(5A):3421-6.
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    106. Lorito M, Woo SL, Garcia I, Colucci G, Harman GE, Pintor-Toro JA, Filippone E, Muccifora S, Lawrence CB, Zoina A, Tuzun S, Scala F, Fernandez IG. Genes from mycoparasitic fungi as a source for improving plant resistance to fungal pathogens. Proc Natl Acad Sci U S A. 1998 Jul 7; 95(14):7860-5.
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    107. Hildebrand KA, Woo SL, Smith DW, Allen CR, Deie M, Taylor BJ, Schmidt CC. The effects of platelet-derived growth factor-BB on healing of the rabbit medial collateral ligament. An in vivo study. Am J Sports Med. 1998 Jul-Aug; 26(4):549-54.
      View in: PubMed
    108. Kosai KI, Finegold MJ, Thi-Huynh BT, Tewson M, Ou CN, Bowles N, Woo SL, Schwall RH, Darlington GJ. Retrovirus-mediated in vivo gene transfer in the replicating liver using recombinant hepatocyte growth factor without liver injury or partial hepatectomy. Hum Gene Ther. 1998 Jun 10; 9(9):1293-301.
      View in: PubMed
    109. Bonnekoh B, Greenhalgh DA, Chen SH, Block A, Rich SS, Krieg T, Woo SL, Roop DR. Ex vivo and in vivo adenovirus-mediated gene therapy strategies induce a systemic anti-tumor immune defence in the B16 melanoma model. J Invest Dermatol. 1998 Jun; 110(6):867-71.
      View in: PubMed
    110. Timme TL, Hall SJ, Barrios R, Woo SL, Aguilar-Cordova E, Thompson TC. Local inflammatory response and vector spread after direct intraprostatic injection of a recombinant adenovirus containing the herpes simplex virus thymidine kinase gene and ganciclovir therapy in mice. Cancer Gene Ther. 1998 Mar-Apr; 5(2):74-82.
      View in: PubMed
    111. Tong XW, Engehausen DG, Kaufman RH, Agoulnik I, Contant C, Freund CT, Oehler MK, Kim TE, Hasenburg A, Woo SL, Kieback DG. Improvement of gene therapy for ovarian cancer by using acyclovir instead of ganciclovir in adenovirus mediated thymidine kinase gene therapy. Anticancer Res. 1998 Mar-Apr; 18(2A):713-8.
      View in: PubMed
    112. Tong X, Engehausen DG, Freund CT, Agoulnik I, Guo Z, Oehler MK, Kim TE, Hasenburg A, Contant CF, Woo SL, Kieback DG. The efficacy of adenovirus-mediated gene therapy of ovarian cancer is enhanced by using the cytomegalovirus promoter. Anticancer Res. 1998 Mar-Apr; 18(2A):719-25.
      View in: PubMed
    113. Bonnekoh B, Greenhalgh DA, Chen SH, Bickenbach J, Block A, Rich SS, Krieg T, Woo SL, Roop DR. Adenovirus-mediated ex vivo immunogene and in vivo combination gene therapy strategies induce a systemic anti-tumor immune defense in the mouse B16 melanoma model. Adv Exp Med Biol. 1998; 451:335-43.
      View in: PubMed
    114. Seiler JG, Chu CR, Amiel D, Woo SL, Gelberman RH. The Marshall R. Urist Young Investigator Award. Autogenous flexor tendon grafts. Biologic mechanisms for incorporation. Clin Orthop Relat Res. 1997 Dec; (345):239-47.
      View in: PubMed
    115. Kwong YL, Chen SH, Kosai K, Finegold M, Woo SL. Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer. Chest. 1997 Nov 5; 112(5):1332-7.
      View in: PubMed
    116. Hall SJ, Chen SH, Woo SL. The promise and reality of cancer gene therapy. Am J Hum Genet. 1997 Oct; 61(4):785-9.
      View in: PubMed
    117. Block A, Chen SH, Kosai K, Finegold M, Woo SL. Adenoviral-mediated herpes simplex virus thymidine kinase gene transfer: regression of hepatic metastasis of pancreatic tumors. Pancreas. 1997 Jul; 15(1):25-34.
      View in: PubMed
    118. Eisensmith RC, Woo SL. Viral vector-mediated gene therapy for hemophilia B. Thromb Haemost. 1997 Jul; 78(1):24-30.
      View in: PubMed
    119. O'Malley BW, Sewell DA, Li D, Kosai K, Chen SH, Woo SL, Duan L. The role of interleukin-2 in combination adenovirus gene therapy for head and neck cancer. Mol Endocrinol. 1997 Jun; 11(6):667-73.
      View in: PubMed
    120. Muzzin P, Eisensmith RC, Copeland KC, Woo SL. Hepatic insulin gene expression as treatment for type 1 diabetes mellitus in rats. Mol Endocrinol. 1997 Jun; 11(6):833-7.
      View in: PubMed
    121. Block A, Windler E, Greten H, Woo SL. [Adenovirus gene therapy for liver metastases of gastrointestinal tumors. Development status and future prospectives]. Dtsch Med Wochenschr. 1997 May 30; 122(22):728-32.
      View in: PubMed
    122. Shine HD, Wyde PR, Aguilar-Cordova E, Chen SH, Woo SL, Grossman RG, Goodman JC. Neurotoxicity of intracerebral injection of a replication-defective adenoviral vector in a semipermissive species (cotton rat). Gene Ther. 1997 Apr; 4(4):275-9.
      View in: PubMed
    123. Tong XW, Agoulnik I, Blankenburg K, Contant CF, Hasenburg A, Runnebaum LB, Stickeler E, Kaplan AL, Woo SL, Kieback DG. Human epithelial ovarian cancer xenotransplants into nude mice can be cured by adenovirus-mediated thymidine kinase gene therapy. Anticancer Res. 1997 Mar-Apr; 17(2A):811-3.
      View in: PubMed
    124. Sutton MA, Berkman SA, Chen SH, Block A, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Woo SL, Lerner SP. Adenovirus-mediated suicide gene therapy for experimental bladder cancer. Urology. 1997 Feb; 49(2):173-80.
      View in: PubMed
    125. Hall SJ, Mutchnik SE, Chen SH, Woo SL, Thompson TC. Adenovirus-mediated herpes simplex virus thymidine kinase gene and ganciclovir therapy leads to systemic activity against spontaneous and induced metastasis in an orthotopic mouse model of prostate cancer. Int J Cancer. 1997 Jan 17; 70(2):183-7.
      View in: PubMed
    126. Scherping SC, Schmidt CC, Georgescu HI, Kwoh CK, Evans CH, Woo SL. Effect of growth factors on the proliferation of ligament fibroblasts from skeletally mature rabbits. Connect Tissue Res. 1997; 36(1):1-8.
      View in: PubMed
    127. Marui T, Niyibizi C, Georgescu HI, Cao M, Kavalkovich KW, Levine RE, Woo SL. Effect of growth factors on matrix synthesis by ligament fibroblasts. J Orthop Res. 1997 Jan; 15(1):18-23.
      View in: PubMed
    128. Muzzin P, Eisensmith RC, Copeland KC, Woo SL. Correction of obesity and diabetes in genetically obese mice by leptin gene therapy. Proc Natl Acad Sci U S A. 1996 Dec 10; 93(25):14804-8.
      View in: PubMed
    129. Hahn TM, Copeland KC, Woo SL. Phenotypic correction of dwarfism by constitutive expression of growth hormone. Endocrinology. 1996 Nov; 137(11):4988-93.
      View in: PubMed
    130. Huang H, Chen SH, Kosai K, Finegold MJ, Woo SL. Gene therapy for hepatocellular carcinoma: long-term remission of primary and metastatic tumors in mice by interleukin-2 gene therapy in vivo. Gene Ther. 1996 Nov; 3(11):980-7.
      View in: PubMed
    131. Caruso M, Pham-Nguyen K, Kwong YL, Xu B, Kosai KI, Finegold M, Woo SL, Chen SH. Adenovirus-mediated interleukin-12 gene therapy for metastatic colon carcinoma. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11302-6.
      View in: PubMed
    132. Bowles NE, Eisensmith RC, Mohuiddin R, Pyron M, Woo SL. A simple and efficient method for the concentration and purification of recombinant retrovirus for increased hepatocyte transduction in vivo. Hum Gene Ther. 1996 Sep 10; 7(14):1735-42.
      View in: PubMed
    133. Guo ZS, Wang LH, Eisensmith RC, Woo SL. Evaluation of promoter strength for hepatic gene expression in vivo following adenovirus-mediated gene transfer. Gene Ther. 1996 Sep; 3(9):802-10.
      View in: PubMed
    134. Kwong YL, Chen SH, Kosai K, Finegold MJ, Woo SL. Adenoviral-mediated suicide gene therapy for hepatic metastases of breast cancer. Cancer Gene Ther. 1996 Sep-Oct; 3(5):339-44.
      View in: PubMed
    135. Chen SH, Kosai K, Xu B, Pham-Nguyen K, Contant C, Finegold MJ, Woo SL. Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival. Cancer Res. 1996 Aug 15; 56(16):3758-62.
      View in: PubMed
    136. Tong XW, Block A, Chen SH, Woo SL, Kieback DG. Adenovirus-mediated thymidine kinase gene transduction in human epithelial ovarian cancer cell lines followed by exposure to ganciclovir. Anticancer Res. 1996 Jul-Aug; 16(4A):1611-7.
      View in: PubMed
    137. Eisensmith RC, Woo SL. Gene therapy for phenylketonuria. Eur J Pediatr. 1996 Jul; 155 Suppl 1:S16-9.
      View in: PubMed
    138. Goodman JC, Trask TW, Chen SH, Woo SL, Grossman RG, Carey KD, Hubbard GB, Carrier DA, Rajagopalan S, Aguilar-Cordova E, Shine HD. Adenoviral-mediated thymidine kinase gene transfer into the primate brain followed by systemic ganciclovir: pathologic, radiologic, and molecular studies. Hum Gene Ther. 1996 Jun 20; 7(10):1241-50.
      View in: PubMed
    139. Yee D, McGuire SE, Brünner N, Kozelsky TW, Allred DC, Chen SH, Woo SL. Adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase in an ascites model of human breast cancer. Hum Gene Ther. 1996 Jun 20; 7(10):1251-7.
      View in: PubMed
    140. Bonnekoh B, Greenhalgh DA, Bundman DS, Kosai K, Chen SH, Finegold MJ, Krieg T, Woo SL, Roop R. Adenoviral-mediated herpes simplex virus-thymidine kinase gene transfer in vivo for treatment of experimental human melanoma. J Invest Dermatol. 1996 Jun; 106(6):1163-8.
      View in: PubMed
    141. Tong XW, Block A, Chen SH, Contant CF, Agoulnik I, Blankenburg K, Kaufman RH, Woo SL, Kieback DG. In vivo gene therapy of ovarian cancer by adenovirus-mediated thymidine kinase gene transduction and ganciclovir administration. Gynecol Oncol. 1996 May; 61(2):175-9.
      View in: PubMed
    142. Gottschalk S, Sparrow JT, Hauer J, Mims MP, Leland FE, Woo SL, Smith LC. A novel DNA-peptide complex for efficient gene transfer and expression in mammalian cells. Gene Ther. 1996 May; 3(5):448-57.
      View in: PubMed
    143. Santos M, Kuzmin AI, Eisensmith RC, Goltsov AA, Woo SL, Barrantes R, de Céspedes C. Phenylketonuria in Costa Rica: preliminary spectrum of PAH mutations and their associations with highly polymorphic haplotypes. Hum Hered. 1996 May-Jun; 46(3):128-31.
      View in: PubMed
    144. O'Malley BW, Cope KA, Chen SH, Li D, Schwarta MR, Woo SL. Combination gene therapy for oral cancer in a murine model. Cancer Res. 1996 Apr 15; 56(8):1737-41.
      View in: PubMed
    145. Eisensmith RC, Martinez DR, Kuzmin AI, Goltsov AA, Brown A, Singh R, Elsas LJ II, Woo SL. Molecular basis of phenylketonuria and a correlation between genotype and phenotype in a heterogeneous southeastern US population. Pediatrics. 1996 Apr; 97(4):512-6.
      View in: PubMed
    146. Fang B, Wang H, Gordon G, Bellinger DA, Read MS, Brinkhous KM, Woo SL, Eisensmith RC. Lack of persistence of E1- recombinant adenoviral vectors containing a temperature-sensitive E2A mutation in immunocompetent mice and hemophilia B dogs. Gene Ther. 1996 Mar; 3(3):217-22.
      View in: PubMed
    147. Eastham JA, Chen SH, Sehgal I, Yang G, Timme TL, Hall SJ, Woo SL, Thompson TC. Prostate cancer gene therapy: herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models. Hum Gene Ther. 1996 Mar 1; 7(4):515-23.
      View in: PubMed
    148. Eisensmith RC, Woo SL. Somatic gene therapy for phenylketonuria and other hepatic deficiencies. J Inherit Metab Dis. 1996; 19(4):412-23.
      View in: PubMed
    149. Colak A, Goodman JC, Chen SH, Woo SL, Grossman RG, Shine HD. Adenovirus-mediated gene therapy in an experimental model of breast cancer metastatic to the brain. Hum Gene Ther. 1995 Oct; 6(10):1317-22.
      View in: PubMed
    150. Jaffe N, Rott E, Woo S, Maor M, Smith M, Black T, Andrassy R. Is there a safe therapeutic window for delivery of chemotherapy prior to initiation of surgery and/or radiation-therapy for treatment of the primary tumor in children with rhabdomyosarcoma. Int J Oncol. 1995 Oct; 7(4):855-62.
      View in: PubMed
    151. Colak A, Goodman JC, Chen SH, Woo SL, Grossman RG, Shine HD. Adenovirus-mediated gene therapy for experimental spinal cord tumors: tumoricidal efficacy and functional outcome. Brain Res. 1995 Sep 11; 691(1-2):76-82.
      View in: PubMed
    152. Gottschalk S, Tweten RK, Smith LC, Woo SL. Efficient gene delivery and expression in mammalian cells using DNA coupled with perfringolysin O. Gene Ther. 1995 Sep; 2(7):498-503.
      View in: PubMed
    153. Kolodka TM, Finegold M, Moss L, Woo SL. Gene therapy for diabetes mellitus in rats by hepatic expression of insulin. Proc Natl Acad Sci U S A. 1995 Apr 11; 92(8):3293-7.
      View in: PubMed
    154. Suh JK, Li Z, Woo SL. Dynamic behavior of a biphasic cartilage model under cyclic compressive loading. J Biomech. 1995 Apr; 28(4):357-64.
      View in: PubMed
    155. Chen SH, Chen XH, Wang Y, Kosai K, Finegold MJ, Rich SS, Woo SL. Combination gene therapy for liver metastasis of colon carcinoma in vivo. Proc Natl Acad Sci U S A. 1995 Mar 28; 92(7):2577-81.
      View in: PubMed
    156. Schmidt CC, Georgescu HI, Kwoh CK, Blomstrom GL, Engle CP, Larkin LA, Evans CH, Woo SL. Effect of growth factors on the proliferation of fibroblasts from the medial collateral and anterior cruciate ligaments. J Orthop Res. 1995 Mar; 13(2):184-90.
      View in: PubMed
    157. Bonnekoh B, Greenhalgh DA, Bundman DS, Eckhardt JN, Longley MA, Chen SH, Woo SL, Roop DR. Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo. J Invest Dermatol. 1995 Mar; 104(3):313-7.
      View in: PubMed
    158. O'Malley BW, Chen SH, Schwartz MR, Woo SL. Adenovirus-mediated gene therapy for human head and neck squamous cell cancer in a nude mouse model. Cancer Res. 1995 Mar 1; 55(5):1080-5.
      View in: PubMed
    159. Kay MA, Graham F, Leland F, Woo SL. Therapeutic serum concentrations of human alpha-1-antitrypsin after adenoviral-mediated gene transfer into mouse hepatocytes. Hepatology. 1995 Mar; 21(3):815-9.
      View in: PubMed
    160. Kuzmin AI, Eisensmith RC, Goltsov AA, Sergeeva NA, Schwartz EI, Woo SL. Complete spectrum of PAH mutations in Tataria: presence of Slavic, Turkic and Scandinavian mutations. Eur J Hum Genet. 1995; 3(4):246-55.
      View in: PubMed
    161. Eisensmith RC, Woo SL. Molecular genetics of phenylketonuria: from molecular anthropology to gene therapy. Adv Genet. 1995; 32:199-271.
      View in: PubMed
    162. Smith LC, Eisensmith RC, Woo SL. Gene therapy in heart disease. Adv Exp Med Biol. 1995; 369:79-88.
      View in: PubMed
    163. Eisensmith RC, Woo SL. Gene therapy for phenylketonuria. Acta Paediatr Suppl. 1994 Dec; 407:124-9.
      View in: PubMed
    164. Eisensmith RC, Woo SL. Population genetics of phenylketonuria. Acta Paediatr Suppl. 1994 Dec; 407:19-26.
      View in: PubMed
    165. Eisensmith RC, Goltsov AA, Woo SL. A simple, rapid, and highly informative PCR-based procedure for prenatal diagnosis and carrier screening of phenylketonuria. Prenat Diagn. 1994 Dec; 14(12):1113-8.
      View in: PubMed
    166. O'Neill CA, Eisensmith RC, Croke DT, Naughten ER, Cahalane SF, Woo SL. Molecular analysis of PKU in Ireland. Acta Paediatr Suppl. 1994 Dec; 407:43-4.
      View in: PubMed
    167. Perez-Cruet MJ, Trask TW, Chen SH, Goodman JC, Woo SL, Grossman RG, Shine HD. Adenovirus-mediated gene therapy of experimental gliomas. J Neurosci Res. 1994 Nov 1; 39(4):506-11.
      View in: PubMed
    168. Fang B, Eisensmith RC, Li XH, Finegold MJ, Shedlovsky A, Dove W, Woo SL. Gene therapy for phenylketonuria: phenotypic correction in a genetically deficient mouse model by adenovirus-mediated hepatic gene transfer. Gene Ther. 1994 Jul; 1(4):247-54.
      View in: PubMed
    169. Kay MA, Woo SL. Gene therapy for metabolic disorders. Trends Genet. 1994 Jul; 10(7):253-7.
      View in: PubMed
    170. Gottschalk S, Cristiano RJ, Smith LC, Woo SL. Folate receptor mediated DNA delivery into tumor cells: potosomal disruption results in enhanced gene expression. Gene Ther. 1994 May; 1(3):185-91.
      View in: PubMed
    171. Chen SH, Shine HD, Goodman JC, Grossman RG, Woo SL. Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):3054-7.
      View in: PubMed
    172. Wang Y, Hahn TM, Tsai SY, Woo SL. Functional characterization of a unique liver gene promoter. J Biol Chem. 1994 Mar 25; 269(12):9137-46.
      View in: PubMed
    173. Li J, Eisensmith RC, Wang T, Lo WH, Huang SZ, Zeng YT, Yuan LF, Liu SR, Woo SL. Phenylketonuria in China: identification and characterization of three novel nucleotide substitutions in the human phenylalanine hydroxylase gene. Hum Mutat. 1994; 3(3):312-4.
      View in: PubMed
    174. Kleiman S, Avigad S, Vanagaite L, Shmuelevitz A, David M, Eisensmith RC, Brand N, Schwartz G, Rey F, Munnich A, Woo SL, Shiloh Y. Origins of hyperphenylalaninemia in Israel. Eur J Hum Genet. 1994; 2(1):24-34.
      View in: PubMed
    175. Scriver CR, Eisensmith RC, Woo SL, Kaufman S. The hyperphenylalaninemias of man and mouse. Annu Rev Genet. 1994; 28:141-65.
      View in: PubMed
    176. Schuler A, Somogyi C, Máté M, Pataki L, Törös I, Woo SL, Eisensmith RC, Fekete G. Cognitive development related to metabolic phenotype and mutation genotype in 25 Hungarian patients with phenylketonuria. J Inherit Metab Dis. 1994; 17(3):372.
      View in: PubMed
    177. Cristiano RJ, Smith LC, Kay MA, Brinkley BR, Woo SL. Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11548-52.
      View in: PubMed
    178. Kolodka TM, Finegold M, Kay MA, Woo SL. Hepatic gene therapy: efficient retroviral-mediated gene transfer into rat hepatocytes in vivo. Somat Cell Mol Genet. 1993 Sep; 19(5):491-7.
      View in: PubMed
    179. Lo WH, Wang T, Eisensmith R, Woo SL. Molecular basis of PKU in China. Chin Med Sci J. 1993 Sep; 8(3):180-5.
      View in: PubMed
    180. Li Q, Kay MA, Finegold M, Stratford-Perricaudet LD, Woo SL. Assessment of recombinant adenoviral vectors for hepatic gene therapy. Hum Gene Ther. 1993 Aug; 4(4):403-9.
      View in: PubMed
    181. Kleiman S, Li J, Schwartz G, Eisensmith RC, Woo SL, Shiloh Y. Inactivation of phenylalanine hydroxylase by a missense mutation, R270S, in a Palestinian kinship with phenylketonuria. Hum Mol Genet. 1993 May; 2(5):605-6.
      View in: PubMed
    182. Goltsov AA, Eisensmith RC, Naughton ER, Jin L, Chakraborty R, Woo SL. A single polymorphic STR system in the human phenylalanine hydroxylase gene permits rapid prenatal diagnosis and carrier screening for phenylketonuria. Hum Mol Genet. 1993 May; 2(5):577-81.
      View in: PubMed
    183. Kleiman S, Vanagaite L, Bernstein J, Schwartz G, Brand N, Elitzur A, Woo SL, Shiloh Y. Phenylketonuria: variable phenotypic outcomes of the R261Q mutation and maternal PKU in the offspring of a healthy homozygote. J Med Genet. 1993 Apr; 30(4):284-8.
      View in: PubMed
    184. Cristiano RJ, Smith LC, Woo SL. Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes. Proc Natl Acad Sci U S A. 1993 Mar 15; 90(6):2122-6.
      View in: PubMed
    185. Weinstein M, Eisensmith RC, Abadie V, Avigad S, Lyonnet S, Schwartz G, Munnich A, Woo SL, Shiloh Y. A missense mutation, S349P, completely inactivates phenylalanine hydroxylase in north African Jews with phenylketonuria. Hum Genet. 1993 Feb; 90(6):645-9.
      View in: PubMed
    186. Svensson E, von Döbeln U, Eisensmith RC, Hagenfeldt L, Woo SL. Relation between genotype and phenotype in Swedish phenylketonuria and hyperphenylalaninemia patients. Eur J Pediatr. 1993 Feb; 152(2):132-9.
      View in: PubMed
    187. Svensson E, Wang Y, Eisensmith RC, Hagenfeldt L, Woo SL. Three polymorphisms but no disease-causing mutations in the proximal part of the promoter of the phenylalanine hydroxylase gene. Eur J Hum Genet. 1993; 1(4):306-13.
      View in: PubMed
    188. Eisensmith RC, Woo SL. Updated listing of haplotypes at the human phenylalanine hydroxylase (PAH) locus. Am J Hum Genet. 1992 Dec; 51(6):1445-8.
      View in: PubMed
    189. Kay MA, Li Q, Liu TJ, Leland F, Toman C, Finegold M, Woo SL. Hepatic gene therapy: persistent expression of human alpha 1-antitrypsin in mice after direct gene delivery in vivo. Hum Gene Ther. 1992 Dec; 3(6):641-7.
      View in: PubMed
    190. Hunter N, Nakayama T, Ito H, Woo S, Milas L. Combination of interleukin-2 and irradiation in therapy of murine tumors. Clin Exp Metastasis. 1992 Nov; 10(6):431-6.
      View in: PubMed
    191. Konecki DS, Wang Y, Trefz FK, Lichter-Konecki U, Woo SL. Structural characterization of the 5' regions of the human phenylalanine hydroxylase gene. Biochemistry. 1992 Sep 8; 31(35):8363-8.
      View in: PubMed
    192. Goltsov AA, Eisensmith RC, Konecki DS, Lichter-Konecki U, Woo SL. Associations between mutations and a VNTR in the human phenylalanine hydroxylase gene. Am J Hum Genet. 1992 Sep; 51(3):627-36.
      View in: PubMed
    193. Wang Y, DeMayo JL, Hahn TM, Finegold MJ, Konecki DS, Lichter-Konecki U, Woo SL. Tissue- and development-specific expression of the human phenylalanine hydroxylase/chloramphenicol acetyltransferase fusion gene in transgenic mice. J Biol Chem. 1992 Jul 25; 267(21):15105-10.
      View in: PubMed
    194. Li J, Eisensmith RC, Wang T, Lo WH, Huang SZ, Zeng YT, Yuan LF, Liu SR, Woo SL. Identification of three novel missense PKU mutations among Chinese. Genomics. 1992 Jul; 13(3):894-5.
      View in: PubMed
    195. Wang T, Okano Y, Eisensmith RC, Lo WH, Huang SZ, Zeng YT, Yuan LF, Liu SR, Woo SL. Identification of three novel PKU mutations among Chinese: evidence for recombination or recurrent mutation at the PAH locus. Genomics. 1992 May; 13(1):230-1.
      View in: PubMed
    196. Reichardt JK, Belmont JW, Levy HL, Woo SL. Characterization of two missense mutations in human galactose-1-phosphate uridyltransferase: different molecular mechanisms for galactosemia. Genomics. 1992 Mar; 12(3):596-600.
      View in: PubMed
    197. Goltsov AA, Eisensmith RC, Woo SL. Detection of the XmnI RFLP at the human PAH locus by PCR. Nucleic Acids Res. 1992 Feb 25; 20(4):927.
      View in: PubMed
    198. Liu TJ, Kay MA, Darlington GJ, Woo SL. Reconstitution of enzymatic activity in hepatocytes of phenylalanine hydroxylase-deficient mice. Somat Cell Mol Genet. 1992 Jan; 18(1):89-96.
      View in: PubMed
    199. Eisensmith RC, Woo SL. Molecular basis of phenylketonuria and related hyperphenylalaninemias: mutations and polymorphisms in the human phenylalanine hydroxylase gene. Hum Mutat. 1992; 1(1):13-23.
      View in: PubMed
    200. Svensson E, Eisensmith RC, Dworniczak B, von Döbeln U, Hagenfeldt L, Horst J, Woo SL. Two missense mutations causing mild hyperphenylalaninemia associated with DNA haplotype 12. Hum Mutat. 1992; 1(2):129-37.
      View in: PubMed
    201. Kleiman S, Bernstein J, Schwartz G, Eisensmith RC, Woo SL, Shiloh Y. A defective splice site at the phenylalanine hydroxylase gene in phenylketonuria and benign hyperphenylalaninemia among Palestinian Arabs. Hum Mutat. 1992; 1(4):340-3.
      View in: PubMed
    202. Kleiman S, Schwartz G, Woo SL, Shiloh Y. A 22-bp deletion in the phenylalanine hydroxylase gene causing phenylketonuria in an Arab family. Hum Mutat. 1992; 1(4):344-6.
      View in: PubMed
    203. Kay MA, Ponder KP, Woo SL. Human gene therapy: present and future. Breast Cancer Res Treat. 1992; 21(2):83-93.
      View in: PubMed
    204. Reichardt JK, Packman S, Woo SL. Molecular characterization of two galactosemia mutations: correlation of mutations with highly conserved domains in galactose-1-phosphate uridyl transferase. Am J Hum Genet. 1991 Oct; 49(4):860-7.
      View in: PubMed
    205. Avigad S, Kleiman S, Weinstein M, Cohen BE, Schwartz G, Woo SL, Shiloh Y. Compound heterozygosity in nonphenylketonuria hyperphenylalanemia: the contribution of mutations for classical phenylketonuria. Am J Hum Genet. 1991 Aug; 49(2):393-9.
      View in: PubMed
    206. Wang T, Okano Y, Eisensmith RC, Lo WH, Huang SZ, Zeng YT, Yuan LF, Liu SR, Woo SL. Missense mutations prevalent in Orientals with phenylketonuria: molecular characterization and clinical implications. Genomics. 1991 Jun; 10(2):449-56.
      View in: PubMed
    207. Huang SZ, Zhou XD, Ren ZR, Zeng YT, Woo SL. A new silent mutation found in the Chinese PAH locus and its role in the prenatal diagnosis of phenylketonuria. Sci China B. 1991 May; 34(5):606-10.
      View in: PubMed
    208. Dasovich M, Konecki D, Lichter-Konecki U, Eisensmith RC, Güttler F, Naughton E, Mullins C, Giovannini M, Riva E, Woo SL. Molecular characterization of PKU allele prevalent in southern Europe and Ireland. Somat Cell Mol Genet. 1991 May; 17(3):303-9.
      View in: PubMed
    209. Reichardt JK, Woo SL. Molecular basis of galactosemia: mutations and polymorphisms in the gene encoding human galactose-1-phosphate uridylyltransferase. Proc Natl Acad Sci U S A. 1991 Apr 1; 88(7):2633-7.
      View in: PubMed
    210. Wang T, Okano Y, Eisensmith RC, Lo WH, Huang SZ, Zeng YT, Woo SL. Identification of a novel phenylketonuria (PKU) mutation in the Chinese: further evidence for multiple origins of PKU in Asia. Am J Hum Genet. 1991 Mar; 48(3):628-30.
      View in: PubMed
    211. Okano Y, Eisensmith RC, Dasovich M, Wang T, Güttler F, Woo SL. A prevalent missense mutation in Northern Europe associated with hyperphenylalaninaemia. Eur J Pediatr. 1991 Mar; 150(5):347-52.
      View in: PubMed
    212. Ponder KP, Gupta S, Leland F, Darlington G, Finegold M, DeMayo J, Ledley FD, Chowdhury JR, Woo SL. Mouse hepatocytes migrate to liver parenchyma and function indefinitely after intrasplenic transplantation. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1217-21.
      View in: PubMed
    213. Eisensmith RC, Woo SL. Phenylketonuria and the phenylalanine hydroxylase gene. Mol Biol Med. 1991 Feb; 8(1):3-18.
      View in: PubMed
    214. Ponder KP, Dunbar RP, Wilson DR, Darlington GJ, Woo SL. Evaluation of relative promoter strength in primary hepatocytes using optimized lipofection. Hum Gene Ther. 1991; 2(1):41-52.
      View in: PubMed
    215. Okano Y, Wang T, Eisensmith RC, Longhi R, Riva E, Giovannini M, Cerone R, Romano C, Woo SL. Phenylketonuria missense mutations in the Mediterranean. Genomics. 1991 Jan; 9(1):96-103.
      View in: PubMed
    216. Ledley FD, Woo SL, Ferry GD, Whisennand HH, Brandt ML, Darlington GJ, Demmler GJ, Finegold MJ, Pokorny WJ, Rosenblatt H, et al. Hepatocellular transplantation in acute hepatic failure and targeting genetic markers to hepatic cells. Hum Gene Ther. 1991; 2(4):331-58.
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    217. Woo SL. Molecular genetic analysis of phenylketonuria and mental retardation. Res Publ Assoc Res Nerv Ment Dis. 1991; 69:193-203.
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    218. Huang SZ, Ren ZR, Zeng YT, Woo SL. PAH 399 GTA (Val)----GTT(Val), a new silent mutation found in the Chinese. Hum Genet. 1991 Jan; 86(3):305-6.
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    219. Lee TH, Finegold MJ, Shen RF, DeMayo JL, Woo SL, Butel JS. Hepatitis B virus transactivator X protein is not tumorigenic in transgenic mice. J Virol. 1990 Dec; 64(12):5939-47.
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    220. Schwartz EI, Khalchitsky SE, Eisensmith RC, Woo SL. Polymerase chain reaction amplification from dried blood spots on Guthrie cards. Lancet. 1990 Sep 8; 336(8715):639-40.
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    221. Armentano D, Thompson AR, Darlington G, Woo SL. Expression of human factor IX in rabbit hepatocytes by retrovirus-mediated gene transfer: potential for gene therapy of hemophilia B. Proc Natl Acad Sci U S A. 1990 Aug; 87(16):6141-5.
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    222. Huang SZ, Zhou XD, Ren ZR, Zeng YT, Woo SL. Prenatal detection of an Arg----Ter mutation at codon 111 of the PAH gene using DNA amplification. Prenat Diagn. 1990 May; 10(5):289-93.
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    223. Okano Y, Wang T, Eisensmith RC, Güttler F, Woo SL. Recurrent mutation in the human phenylalanine hydroxylase gene. Am J Hum Genet. 1990 May; 46(5):919-24.
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    224. Ledley FD, Grenett HE, Dunbar BS, Woo SL. Mouse phenylalanine hydroxylase. Homology and divergence from human phenylalanine hydroxylase. Biochem J. 1990 Apr 15; 267(2):399-405.
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    225. Avigad S, Cohen BE, Bauer S, Schwartz G, Frydman M, Woo SL, Niny Y, Shiloh Y. A single origin of phenylketonuria in Yemenite Jews. Nature. 1990 Mar 8; 344(6262):168-70.
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    226. Wang T, Okano Y, Eisensmith RC, Fekete G, Schuler D, Berencsi G, Nasz I, Woo SL. Molecular genetics of PKU in eastern Europe: a nonsense mutation associated with haplotype 4 of the phenylalanine hydroxylase gene. Somat Cell Mol Genet. 1990 Jan; 16(1):85-90.
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    227. Butel JS, Sepulveda AR, Finegold MJ, Woo SL. SV40 large T antigen directed by regulatory elements of the human alpha-1-antitrypsin gene. A transgenic mouse system that exhibits stages in liver carcinogenesis. Intervirology. 1990; 31(2-4):85-100.
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    228. Okano Y, Wang T, Eisensmith RC, Steinmann B, Gitzelmann R, Woo SL. Missense mutations associated with RFLP haplotypes 1 and 4 of the human phenylalanine hydroxylase gene. Am J Hum Genet. 1990 Jan; 46(1):18-25.
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    229. Sifers RN, Ledley FD, Reed-Fourquet L, Ledbetter DH, Ledbetter SA, Woo SL. Complete cDNA sequence and chromosomal localization of mouse alpha 1-antitrypsin. Genomics. 1990 Jan; 6(1):100-4.
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    230. Wang T, Okano Y, Eisensmith R, Huang SZ, Zeng YT, Lo WH, Woo SL. Molecular genetics of phenylketonuria in Orientals: linkage disequilibrium between a termination mutation and haplotype 4 of the phenylalanine hydroxylase gene. Am J Hum Genet. 1989 Nov; 45(5):675-80.
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    231. Sepulveda AR, Finegold MJ, Smith B, Slagle BL, DeMayo JL, Shen RF, Woo SL, Butel JS. Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene. Cancer Res. 1989 Nov 1; 49(21):6108-17.
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    232. Milas L, Sersa G, Willingham V, Hunter N, Woo S. Adoptive immunotherapy as an adjunctive treatment to thoracic irradiation for pulmonary tumor deposits in mice. Cancer Res. 1989 Sep 15; 49(18):4979-82.
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    233. Sullivan SE, Moore SD, Connor JM, King M, Cockburn F, Steinmann B, Gitzelmann R, Daiger SP, Woo SL. Haplotype distribution of the human phenylalanine hydroxylase locus in Scotland and Switzerland. Am J Hum Genet. 1989 May; 44(5):652-9.
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    234. Carlson JA, Rogers BB, Sifers RN, Finegold MJ, Clift SM, DeMayo FJ, Bullock DW, Woo SL. Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice. J Clin Invest. 1989 Apr; 83(4):1183-90.
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    235. Shen RF, Clift SM, DeMayo JL, Sifers RN, Finegold MJ, Woo SL. Tissue-specific regulation of human alpha 1-antitrypsin gene expression in transgenic mice. DNA. 1989 Mar; 8(2):101-8.
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    236. Sifers RN, Hardick CP, Woo SL. Disruption of the 290-342 salt bridge is not responsible for the secretory defect of the PiZ alpha 1-antitrypsin variant. J Biol Chem. 1989 Feb 15; 264(5):2997-3001.
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    237. Woo SL. Molecular basis and population genetics of phenylketonuria. Biochemistry. 1989 Jan 10; 28(1):1-7.
      View in: PubMed
    238. Zeng YT, Huang SZ, Chen MJ, Zhang ML, Ren ZR, Xu YH, Peng SF, Woo SL. A study on Chinese phenylalanine hydroxylase gene restriction site polymorphism. Sci Sin B. 1988 Dec; 31(12):1447-53.
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    239. Peng H, Armentano D, MacKenzie-Graham L, Shen RF, Darlington G, Ledley FD, Woo SL. Retroviral-mediated gene transfer and expression of human phenylalanine hydroxylase in primary mouse hepatocytes. Proc Natl Acad Sci U S A. 1988 Nov; 85(21):8146-50.
      View in: PubMed
    240. Woo SL. Collation of RFLP haplotypes at the human phenylalanine hydroxylase (PAH) locus. Am J Hum Genet. 1988 Nov; 43(5):781-3.
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    241. Li Y, Shen RF, Tsai SY, Woo SL. Multiple hepatic trans-acting factors are required for in vitro transcription of the human alpha-1-antitrypsin gene. Mol Cell Biol. 1988 Oct; 8(10):4362-9.
      View in: PubMed
    242. Ledley FD, Koch R, Jew K, Beaudet A, O'Brien WE, Bartos DP, Woo SL. Phenylalanine hydroxylase expression in liver of a fetus with phenylketonuria. J Pediatr. 1988 Sep; 113(3):463-8.
      View in: PubMed
    243. Carlson JA, Rogers BB, Sifers RN, Hawkins HK, Finegold MJ, Woo SL. Multiple tissues express alpha 1-antitrypsin in transgenic mice and man. J Clin Invest. 1988 Jul; 82(1):26-36.
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    244. Sifers RN, Brashears-Macatee S, Kidd VJ, Muensch H, Woo SL. A frameshift mutation results in a truncated alpha 1-antitrypsin that is retained within the rough endoplasmic reticulum. J Biol Chem. 1988 May 25; 263(15):7330-5.
      View in: PubMed
    245. Lichter-Konecki U, Konecki DS, DiLella AG, Brayton K, Marvit J, Hahn TM, Trefz FK, Woo SL. Phenylalanine hydroxylase deficiency caused by a single base substitution in an exon of the human phenylalanine hydroxylase gene. Biochemistry. 1988 Apr 19; 27(8):2881-5.
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    246. Lichter-Konecki U, Schlotter M, Konecki DS, Labeit S, Woo SL, Trefz FK. Linkage disequilibrium between mutation and RFLP haplotype at the phenylalanine hydroxylase locus in the German population. Hum Genet. 1988 Apr; 78(4):347-52.
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    247. McDonald JD, Cotton RG, Jennings I, Ledley FD, Woo SL, Bode VC. Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity. J Neurochem. 1988 Feb; 50(2):655-7.
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    248. Scriver CR, Kaufman S, Woo SL. Mendelian hyperphenylalaninemia. Annu Rev Genet. 1988; 22:301-21.
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    249. Ledley FD, Ledbetter SA, Ledbetter DH, Woo SL. Localization of mouse phenylalanine hydroxylase locus on chromosome 10. Cytogenet Cell Genet. 1988; 47(3):125-6.
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    250. Shen RF, Li Y, Sifers RN, Wang H, Hardick C, Tsai SY, Woo SL. Tissue-specific expression of the human alpha 1-antitrypsin gene is controlled by multiple cis-regulatory elements. Nucleic Acids Res. 1987 Oct 26; 15(20):8399-415.
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    251. Ledley FD, Darlington GJ, Hahn T, Woo SL. Retroviral gene transfer into primary hepatocytes: implications for genetic therapy of liver-specific functions. Proc Natl Acad Sci U S A. 1987 Aug; 84(15):5335-9.
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    252. DiLella AG, Woo SL. Molecular basis of phenylketonuria and its clinical applications. Mol Biol Med. 1987 Aug; 4(4):183-92.
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    253. Grenett HE, Ledley FD, Reed LL, Woo SL. Full-length cDNA for rabbit tryptophan hydroxylase: functional domains and evolution of aromatic amino acid hydroxylases. Proc Natl Acad Sci U S A. 1987 Aug; 84(16):5530-4.
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    254. Marvit J, DiLella AG, Brayton K, Ledley FD, Robson KJ, Woo SL. GT to AT transition at a splice donor site causes skipping of the preceding exon in phenylketonuria. Nucleic Acids Res. 1987 Jul 24; 15(14):5613-28.
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    255. DiLella AG, Marvit J, Brayton K, Woo SL. An amino-acid substitution involved in phenylketonuria is in linkage disequilibrium with DNA haplotype 2. Nature. 1987 May 28-Jun 3; 327(6120):333-6.
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    256. Chakraborty R, Lidsky AS, Daiger SP, Güttler F, Sullivan S, Dilella AG, Woo SL. Polymorphic DNA haplotypes at the human phenylalanine hydroxylase locus and their relationship with phenylketonuria. Hum Genet. 1987 May; 76(1):40-6.
      View in: PubMed
    257. Lockyer J, Cook RG, Milstien S, Kaufman S, Woo SL, Ledley FD. Structure and expression of human dihydropteridine reductase. Proc Natl Acad Sci U S A. 1987 May; 84(10):3329-33.
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    258. Ledley FD, Hahn T, Woo SL. Selection for phenylalanine hydroxylase activity in cells transformed with recombinant retroviruses. Somat Cell Mol Genet. 1987 Mar; 13(2):145-54.
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    259. Sifers RN, Carlson JA, Clift SM, DeMayo FJ, Bullock DW, Woo SL. Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice. Nucleic Acids Res. 1987 Feb 25; 15(4):1459-75.
      View in: PubMed
    260. Ledley FD, Grenett HE, Woo SL. Biochemical characterization of recombinant human phenylalanine hydroxylase produced in Escherichia coli. J Biol Chem. 1987 Feb 15; 262(5):2228-33.
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    261. Ledley FD, Woo SL. P-chlorophenylalanine does not inhibit production of recombinant human phenylalanine hydroxylase in NIH3T3 cells or E. coli. Biochem Biophys Res Commun. 1987 Jan 30; 142(2):302-8.
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    262. Güttler F, DiLella AG, Ledley FD, Lidsky AS, Kvok SC, Marvit J, Woo SL. Molecular biology of phenylketonuria. Eur J Pediatr. 1987; 146 Suppl 1:A5-11.
      View in: PubMed
    263. Güttler F, Ledley FD, Lidsky AS, DiLella AG, Sullivan SE, Woo SL. Correlation between polymorphic DNA haplotypes at phenylalanine hydroxylase locus and clinical phenotypes of phenylketonuria. J Pediatr. 1987 Jan; 110(1):68-71.
      View in: PubMed
    264. Woo SL, DiLella AG, Marvit J, Ledley FD. Molecular basis of phenylketonuria and recombinant DNA strategies for its therapy. Enzyme. 1987; 38(1-4):207-13.
      View in: PubMed
    265. Ledley FD, Grenett HE, Bartos DP, Woo SL. Retroviral mediated transfer and expression of human alpha 1-antitrypsin in cultured cells. Gene. 1987; 61(1):113-8.
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    266. Codina J, Stengel D, Woo SL, Birnbaumer L. Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical. FEBS Lett. 1986 Oct 27; 207(2):187-92.
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    267. Mattera R, Codina J, Crozat A, Kidd V, Woo SL, Birnbaumer L. Identification by molecular cloning of two forms of the alpha-subunit of the human liver stimulatory (GS) regulatory component of adenylyl cyclase. FEBS Lett. 1986 Sep 29; 206(1):36-42.
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    268. DiLella AG, Marvit J, Lidsky AS, Güttler F, Woo SL. Tight linkage between a splicing mutation and a specific DNA haplotype in phenylketonuria. Nature. 1986 Aug 28-Sep 3; 322(6082):799-803.
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    269. Muensch H, Gaidulis L, Kueppers F, So SY, Escano G, Kidd VJ, Woo SL. Complete absence of serum alpha-1-antitrypsin in conjunction with an apparently normal gene structure. Am J Hum Genet. 1986 Jun; 38(6):898-907.
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    270. Ledley FD, Levy HL, Woo SL. Molecular analysis of the inheritance of phenylketonuria and mild hyperphenylalaninemia in families with both disorders. N Engl J Med. 1986 May 15; 314(20):1276-80.
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    271. DiLella AG, Kwok SC, Ledley FD, Marvit J, Woo SL. Molecular structure and polymorphic map of the human phenylalanine hydroxylase gene. Biochemistry. 1986 Feb 25; 25(4):743-9.
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    272. Daiger SP, Lidsky AS, Chakraborty R, Koch R, Güttler F, Woo SL. Polymorphic DNA haplotypes at the phenylalanine hydroxylase locus in prenatal diagnosis of phenylketonuria. Lancet. 1986 Feb 1; 1(8475):229-32.
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    273. Güttler F, Woo SL. Molecular genetics of PKU. J Inherit Metab Dis. 1986; 9 Suppl 1:58-68.
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    274. Ledley FD, Woo SL. Molecular basis of alpha 1-antitrypsin deficiency and its potential therapy by gene transfer. J Inherit Metab Dis. 1986; 9 Suppl 1:85-91.
      View in: PubMed
    275. Ledley FD, Grenett HE, McGinnis-Shelnutt M, Woo SL. Retroviral-mediated gene transfer of human phenylalanine hydroxylase into NIH 3T3 and hepatoma cells. Proc Natl Acad Sci U S A. 1986 Jan; 83(2):409-13.
      View in: PubMed
    276. Woo SL, DiLella AG, Marvit J, Ledley FD. Molecular basis of phenylketonuria and potential somatic gene therapy. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt 1:395-401.
      View in: PubMed
    277. Schroeder WT, Miller MF, Woo SL, Saunders GF. Chromosomal localization of the human alpha 1-antitrypsin gene (PI) to 14q31-32. Am J Hum Genet. 1985 Sep; 37(5):868-72.
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    278. Lidsky AS, Law ML, Morse HG, Kao FT, Rabin M, Ruddle FH, Woo SL. Regional mapping of the phenylalanine hydroxylase gene and the phenylketonuria locus in the human genome. Proc Natl Acad Sci U S A. 1985 Sep; 82(18):6221-5.
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    279. Ledley FD, DiLella AG, Kwok SC, Woo SL. Homology between phenylalanine and tyrosine hydroxylases reveals common structural and functional domains. Biochemistry. 1985 Jul 2; 24(14):3389-94.
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    280. Lidsky AS, Ledley FD, DiLella AG, Kwok SC, Daiger SP, Robson KJ, Woo SL. Extensive restriction site polymorphism at the human phenylalanine hydroxylase locus and application in prenatal diagnosis of phenylketonuria. Am J Hum Genet. 1985 Jul; 37(4):619-34.
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    281. Snead ML, Lau EC, Zeichner-David M, Fincham AG, Woo SL, Slavkin HC. DNA sequence for cloned cDNA for murine amelogenin reveal the amino acid sequence for enamel-specific protein. Biochem Biophys Res Commun. 1985 Jun 28; 129(3):812-8.
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    282. Ledley FD, Grenett HE, DiLella AG, Kwok SC, Woo SL. Gene transfer and expression of human phenylalanine hydroxylase. Science. 1985 Apr 5; 228(4695):77-9.
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    283. Lidsky AS, Güttler F, Woo SL. Prenatal diagnosis of classic phenylketonuria by DNA analysis. Lancet. 1985 Mar 9; 1(8428):549-51.
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    284. Kwok SC, Ledley FD, DiLella AG, Robson KJ, Woo SL. Nucleotide sequence of a full-length complementary DNA clone and amino acid sequence of human phenylalanine hydroxylase. Biochemistry. 1985 Jan 29; 24(3):556-61.
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    285. DiLella AG, Ledley FD, Rey F, Munnich A, Woo SL. Detection of phenylalanine hydroxylase messenger RNA in liver biopsy samples from patients with phenylketonuria. Lancet. 1985 Jan 19; 1(8421):160-1.
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    286. Woo SL, Güttler F, Ledley FD, Lidsky AS, Kwok SC, DiLella AG, Robson KJ. The human phenylalanine hydroxylase gene. Prog Clin Biol Res. 1985; 177:123-35.
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    287. Robson KJ, Beattie W, James RJ, Cotton RC, Morgan FJ, Woo SL. Sequence comparison of rat liver phenylalanine hydroxylase and its cDNA clones. Biochemistry. 1984 Nov 20; 23(24):5671-5.
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    288. Long GL, Chandra T, Woo SL, Davie EW, Kurachi K. Complete sequence of the cDNA for human alpha 1-antitrypsin and the gene for the S variant. Biochemistry. 1984 Oct 9; 23(21):4828-37.
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    289. Woo SL. Prenatal diagnosis and carrier detection of classic phenylketonuria by gene analysis. Pediatrics. 1984 Sep; 74(3):412-23.
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    290. Kidd VJ, Woo SL. Recombinant DNA probes used to detect genetic disorders of the liver. Hepatology. 1984 Jul-Aug; 4(4):731-6.
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    291. Lidksy AS, Robson KJ, Thirumalachary C, Barker PE, Ruddle FH, Woo SL. The PKU locus in man is on chromosome 12. Am J Hum Genet. 1984 May; 36(3):527-33.
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    292. Woo SL, Lidsky AS, Güttler F, Thirumalachary C, Robson KJ. Prenatal diagnosis of classical phenylketonuria by gene mapping. JAMA. 1984 Apr 20; 251(15):1998-2002.
      View in: PubMed
    293. Woo SL, Robson JH, Güttler F. The possibility for prenatal diagnosis of PKU by linkage analyses based on phenylalanine hydroxylase locus specific DNA-polymorphisms. J Inherit Metab Dis. 1984; 7 Suppl 2:139-40.
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    294. Snead ML, Zeichner-David M, Chandra T, Robson KJ, Woo SL, Slavkin HC. Construction and identification of mouse amelogenin cDNA clones. Proc Natl Acad Sci U S A. 1983 Dec; 80(23):7254-8.
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    295. Woo SL, Lidsky AS, Güttler F, Chandra T, Robson KJ. Cloned human phenylalanine hydroxylase gene allows prenatal diagnosis and carrier detection of classical phenylketonuria. Nature. 1983 Nov 10-16; 306(5939):151-5.
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    296. Lai EC, Kao FT, Law ML, Woo SL. Assignment of the alpha 1-antitrypsin gene and a sequence-related gene to human chromosome 14 by molecular hybridization. Am J Hum Genet. 1983 May; 35(3):385-92.
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    297. Chandra T, Stackhouse R, Kidd VJ, Woo SL. Isolation and sequence characterization of a cDNA clone of human antithrombin III. Proc Natl Acad Sci U S A. 1983 Apr; 80(7):1845-8.
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    298. Shen XZ, Tsai MJ, Bullock DW, Woo SL. Hormonal regulation of rabbit uteroglobin gene transcription. Endocrinology. 1983 Mar; 112(3):871-6.
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    299. Lagacé L, Chandra T, Woo SL, Means AR. Identification of multiple species of calmodulin messenger RNA using a full length complementary DNA. J Biol Chem. 1983 Feb 10; 258(3):1684-8.
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    300. Zarucki-Schulz T, Tsai SY, Itakura K, Soberon X, Wallace RB, Tsai MJ, Woo SL, O'Malley BW. Point mutagenesis of the ovalbumin gene promoter sequence and its effect on in vitro transcription. J Biol Chem. 1982 Sep 25; 257(18):11070-7.
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    301. Robson KJ, Chandra T, MacGillivray RT, Woo SL. Polysome immunoprecipitation of phenylalanine hydroxylase mRNA from rat liver and cloning of its cDNA. Proc Natl Acad Sci U S A. 1982 Aug; 79(15):4701-5.
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    302. Chandra T, Kurachi K, Davie EW, Woo SL. Induction of alpha 1-antitrypsin mRNA and cloning of its cDNA. Biochem Biophys Res Commun. 1981 Nov 30; 103(2):751-8.
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    303. Kurachi K, Chandra T, Degen SJ, White TT, Marchioro TL, Woo SL, Davie EW. Cloning and sequence of cDNA coding for alpha 1-antitrypsin. Proc Natl Acad Sci U S A. 1981 Nov; 78(11):6826-30.
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    304. Munjaal RP, Chandra T, Woo SL, Dedman JR, Means AR. A cloned calmodulin structural gene probe is complementary to DNA sequences from diverse species. Proc Natl Acad Sci U S A. 1981 Apr; 78(4):2330-4.
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    305. Chandra T, Bullock DW, Woo SL. Hormonally regulated mammalian gene expression: steady-state level and nucleotide sequence of rabbit uteroglobin mRNA. DNA. 1981; 1(1):19-26.
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    306. Colbert DA, Knoll BJ, Woo SL, Mace ML, Tsai MJ, O'Malley BW. Differential hormonal responsiveness of the ovalbumin gene and its pseudogenes in the chick oviduct. Biochemistry. 1980 Nov 25; 19(24):5586-92.
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    307. MacGillivray RT, Degen SJ, Chandra T, Woo SL, Davie EW. Cloning and analysis of a cDNA coding for bovine prothrombin. Proc Natl Acad Sci U S A. 1980 Sep; 77(9):5153-7.
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    308. Chandra T, Woo SL, Bullock DW. Cloning of the rabbit uteroglobin structural gene. Biochem Biophys Res Commun. 1980 Jul 16; 95(1):197-204.
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    309. Lai EC, Woo SL, Bordelon-Riser ME, Fraser TH, O'Malley BW. Ovalbumin is synthesized in mouse cells transformed with the natural chicken ovalbumin gene. Proc Natl Acad Sci U S A. 1980 Jan; 77(1):244-8.
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    310. Lai EC, Stein JP, Catterall JF, Woo SL, Mace ML, Means AR, O'Malley BW. Molecular structure and flanking nucleotide sequences of the natural chicken ovomucoid gene. Cell. 1979 Nov; 18(3):829-42.
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    311. Dugaiczyk A, Woo SL, Colbert DA, Lai EC, Mace ML, O'Malley BW. The ovalbumin gene: cloning and molecular organization of the entire natural gene. Proc Natl Acad Sci U S A. 1979 May; 76(5):2253-7.
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    312. Woo SL. A sensitive and rapid method for recombinant phage screening. Methods Enzymol. 1979; 68:389-95.
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    313. Woo SL, Dugaiczyk A, Tsai MJ, Lai EC, Catterall JF, O'Malley BW. The ovalbumin gene: cloning of the natural gene. Proc Natl Acad Sci U S A. 1978 Aug; 75(8):3688-92.
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    314. Lai EC, Woo SL, Dugaiczyk A, Catterall JF, O'Malley BW. The ovalbumin gene: structural sequences in native chicken DNA are not contiguous. Proc Natl Acad Sci U S A. 1978 May; 75(5):2205-9.
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    315. McReynolds LA, Monahan JJ, Bendure DW, Woo SL, Paddock GV, Salser W, Dorson J, Moses RE, O'Malley BW. The ovalbumin gene. Insertion of ovalbumin gene sequences in chimeric bacterial plasmids. J Biol Chem. 1977 Mar 25; 252(6):1840-3.
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    316. Gillam SS, Woo SL, Woolf LI. The isolation and properties of phenylalanine hydroxylase from rat liver. Biochem J. 1974 Jun; 139(3):731-9.
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    317. Woo SL, Gillam SS, Woolf LI. The isolation and properties of phenylalanine hydroxylase from human liver. Biochem J. 1974 Jun; 139(3):741-9.
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