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Last Name
Institution

Charles V. Mobbs

TitlePROFESSOR
InstitutionMount Sinai
DepartmentGeriatrics and Palliative Medicine
Address
    Other Positions
    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentNeuroscience

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentEndocrinology, Diabetes and Bone Disease


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mobbs CV, Moreno CL, Poplawski M. Metabolic mystery: aging, obesity, diabetes, and the ventromedial hypothalamus. Trends Endocrinol Metab. 2013 Oct; 24(10):488-94.
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    2. Kim ES, Isoda F, Kurland I, Mobbs CV. Glucose-induced metabolic memory in Schwann cells: prevention by PPAR agonists. Endocrinology. 2013 Sep; 154(9):3054-66.
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    3. Mobbs CV, Mastaitis J, Isoda F, Poplawski M. Treatment of diabetes and diabetic complications with a ketogenic diet. J Child Neurol. 2013 Aug; 28(8):1009-14.
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    4. Mobbs CV, Moreno C. Hypothalamic EphA5 facilitates counterregulatory responses: possible role for bidirectional signaling leading to bistability that enhances responsiveness to hypoglycemia. Diabetes. 2013 Apr; 62(4):1014-6.
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    5. Moreno C, Yang L, Dacks P, Isoda F, Poplawski M, Mobbs CV. Regulation of peripheral metabolism by substrate partitioning in the brain. Endocrinol Metab Clin North Am. 2013 Mar; 42(1):67-80.
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    6. Kefaloyianni E, Lyssand JS, Moreno C, Delaroche D, Hong M, Fenyö D, Mobbs CV, Neubert TA, Coetzee WA. Comparative proteomic analysis of the ATP-sensitive K+ channel complex in different tissue types. Proteomics. 2013 Jan; 13(2):368-78.
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    7. Dacks PA, Moreno CL, Kim ES, Marcellino BK, Mobbs CV. Role of the hypothalamus in mediating protective effects of dietary restriction during aging. Front Neuroendocrinol. 2013 Apr; 34(2):95-106.
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    8. Schwartz E, Mobbs CV. Hypothalamic BDNF and obesity: found in translation. Nat Med. 2012 Apr; 18(4):496-7.
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    9. Yang L, Isoda F, Yen K, Kleopoulos SP, Janssen W, Fan X, Mastaitis J, Dunn-Meynell A, Levin B, McCrimmon R, Sherwin R, Musatov S, Mobbs CV. Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes. Am J Physiol Endocrinol Metab. 2012 Apr 15; 302(8):E987-91.
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    10. Lublin A, Isoda F, Patel H, Yen K, Nguyen L, Hajje D, Schwartz M, Mobbs C. FDA-approved drugs that protect mammalian neurons from glucose toxicity slow aging dependent on cbp and protect against proteotoxicity. PLoS One. 2011; 6(11):e27762.
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    11. Poritsanos NJ, Lew PS, Fischer J, Mobbs CV, Nagy JI, Wong D, Rüther U, Mizuno TM. Impaired hypothalamic Fto expression in response to fasting and glucose in obese mice. Nutr Diabetes. 2011; 1:e19.
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    12. Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett AM, Shanabrough M, Mobbs CV, Yang X, Gao XB, Horvath TL. Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity. Nat Med. 2011 Sep; 17(9):1121-7.
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    13. Poplawski MM, Mastaitis JW, Isoda F, Grosjean F, Zheng F, Mobbs CV. Reversal of diabetic nephropathy by a ketogenic diet. PLoS One. 2011; 6(4):e18604.
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    14. Poplawski MM, Mastaitis JW, Yang XJ, Mobbs CV. Hypothalamic responses to fasting indicate metabolic reprogramming away from glycolysis toward lipid oxidation. Endocrinology. 2010 Nov; 151(11):5206-17.
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    15. Poplawski MM, Mastaitis JW, Mobbs CV. Naloxone, but not valsartan, preserves responses to hypoglycemia after antecedent hypoglycemia: role of metabolic reprogramming in counterregulatory failure. Diabetes. 2011 Jan; 60(1):39-46.
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    16. Zhang M, Poplawski M, Yen K, Cheng H, Bloss E, Zhu X, Patel H, Mobbs CV. Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling. PLoS Biol. 2009 Nov; 7(11):e1000245.
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    17. Yen K, Mobbs CV. Evidence for only two independent pathways for decreasing senescence in Caenorhabditis elegans. Age (Dordr). 2010 Mar; 32(1):39-49.
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    18. Cheng H, Isoda F, Mobbs CV. Estradiol impairs hypothalamic molecular responses to hypoglycemia. Brain Res. 2009 Jul 14; 1280:77-83.
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    19. Yen K, Patel HB, Lublin AL, Mobbs CV. SOD isoforms play no role in lifespan in ad lib or dietary restricted conditions, but mutational inactivation of SOD-1 reduces life extension by cold. Mech Ageing Dev. 2009 Mar; 130(3):173-8.
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    20. Yen K, Steinsaltz D, Mobbs CV. Validated analysis of mortality rates demonstrates distinct genetic mechanisms that influence lifespan. Exp Gerontol. 2008 Dec; 43(12):1044-51.
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    21. Yen K, Mobbs CV. Chemosensory and caloric mechanisms influence distinct components of mortality rate. Exp Gerontol. 2008 Dec; 43(12):1058-60.
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    22. Cheng H, Isoda F, Belsham DD, Mobbs CV. Inhibition of agouti-related peptide expression by glucose in a clonal hypothalamic neuronal cell line is mediated by glycolysis, not oxidative phosphorylation. Endocrinology. 2008 Feb; 149(2):703-10.
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    23. Musatov S, Chen W, Pfaff DW, Mobbs CV, Yang XJ, Clegg DJ, Kaplitt MG, Ogawa S. Silencing of estrogen receptor alpha in the ventromedial nucleus of hypothalamus leads to metabolic syndrome. Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7):2501-6.
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    24. Yang XJ, Mastaitis J, Mizuno T, Mobbs CV. Glucokinase regulates reproductive function, glucocorticoid secretion, food intake, and hypothalamic gene expression. Endocrinology. 2007 Apr; 148(4):1928-32.
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    25. Mobbs CV, Mastaitis JW, Zhang M, Isoda F, Cheng H, Yen K. Secrets of the lac operon. Glucose hysteresis as a mechanism in dietary restriction, aging and disease. Interdiscip Top Gerontol. 2007; 35:39-68.
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    26. Mobbs CV. The "domino theory" of hunger: the hypothalamus is hot. Cell Metab. 2007 Jan; 5(1):1-2.
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    27. Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, Leranth C, Toran-Allerand D, Priest CA, Roberts JL, Gao XB, Mobbs C, Shulman GI, Diano S, Horvath TL. Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med. 2007 Jan; 13(1):89-94.
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    28. Mobbs CV, Mastaitis J, Yen K, Schwartz J, Mohan V, Poplawski M, Isoda F. Low-carbohydrate diets cause obesity, low-carbohydrate diets reverse obesity: a metabolic mechanism resolving the paradox. Appetite. 2007 Mar; 48(2):135-8.
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    29. Mobbs CV. Fathead: the gain in brain falls mainly with leptin wane. Endocrinology. 2006 Feb; 147(2):645-6.
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    30. Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology. FASEB J. 2005 Dec; 19(14):2081-2.
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    31. Watson E, Hahm S, Mizuno TM, Windsor J, Montgomery C, Scherer PE, Mobbs CV, Salton SR. VGF ablation blocks the development of hyperinsulinemia and hyperglycemia in several mouse models of obesity. Endocrinology. 2005 Dec; 146(12):5151-63.
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    32. Mobbs CV, Isoda F, Makimura H, Mastaitis J, Mizuno T, Shu IW, Yen K, Yang XJ. Impaired glucose signaling as a cause of obesity and the metabolic syndrome: the glucoadipostatic hypothesis. Physiol Behav. 2005 May 19; 85(1):3-23.
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    33. Mastaitis JW, Wurmbach E, Cheng H, Sealfon SC, Mobbs CV. Acute induction of gene expression in brain and liver by insulin-induced hypoglycemia. Diabetes. 2005 Apr; 54(4):952-8.
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    34. Mobbs CV. Not wisely but too well: aging as a cost of neuroendocrine activity. Sci Aging Knowledge Environ. 2004 Sep 1; 2004(35):pe33.
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    35. Mizuno T, Shu IW, Makimura H, Mobbs C. Obesity over the life course. Sci Aging Knowledge Environ. 2004 Jun 16; 2004(24):re4.
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    36. Yen K, Mastitis JW, Mobbs CV. Lifespan is not determined by metabolic rate: evidence from fishes and C. elegans. Exp Gerontol. 2004 Jun; 39(6):947-9.
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    37. Mobbs CV, Yen K, Mastaitis J, Nguyen H, Watson E, Wurmbach E, Sealfon SC, Brooks A, Salton SR. Mining microarrays for metabolic meaning: nutritional regulation of hypothalamic gene expression. Neurochem Res. 2004 Jun; 29(6):1093-103.
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    38. Mizuno TM, Funabashi T, Kleopoulos SP, Mobbs CV. Specific preservation of biosynthetic responses to insulin in adipose tissue may contribute to hyperleptinemia in insulin-resistant obese mice. J Nutr. 2004 May; 134(5):1045-50.
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    39. Héron-Milhavet L, Xue-Jun Y, Vannucci SJ, Wood TL, Willing LB, Stannard B, Hernandez-Sanchez C, Mobbs C, Virsolvy A, LeRoith D. Protection against hypoxic-ischemic injury in transgenic mice overexpressing Kir6.2 channel pore in forebrain. Mol Cell Neurosci. 2004 Apr; 25(4):585-93.
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    40. Ho L, Qin W, Pompl PN, Xiang Z, Wang J, Zhao Z, Peng Y, Cambareri G, Rocher A, Mobbs CV, Hof PR, Pasinetti GM. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease. FASEB J. 2004 May; 18(7):902-4.
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    41. Tanaka SI, Yamakawa T, Kimura M, Aoki I, Kamei J, Okuda K, Mobbs C. Daily nasal inoculation with the insulin gene ameliorates diabetes in mice. Diabetes Res Clin Pract. 2004 Jan; 63(1):1-9.
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    42. Holen T, Mobbs CV. Lobotomy of genes: use of RNA interference in neuroscience. Neuroscience. 2004; 126(1):1-7.
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    43. Yang XJ, Kow LM, Pfaff DW, Mobbs CV. Metabolic pathways that mediate inhibition of hypothalamic neurons by glucose. Diabetes. 2004 Jan; 53(1):67-73.
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    44. Isoda F, Shiry L, Abergel J, Allan G, Mobbs C. D-chiro-Inositol enhances effects of hypothalamic toxin gold-thioglucose. Brain Res. 2003 Dec 12; 993(1-2):172-6.
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    45. Mizuno TM, Kelley KA, Pasinetti GM, Roberts JL, Mobbs CV. Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese mice. Diabetes. 2003 Nov; 52(11):2675-83.
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    46. Shu IW, Lindenberg DL, Mizuno TM, Roberts JL, Mobbs CV. The fatty acid synthase inhibitor cerulenin and feeding, like leptin, activate hypothalamic pro-opiomelanocortin (POMC) neurons. Brain Res. 2003 Sep 19; 985(1):1-12.
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    47. Li G, Mobbs CV, Scarpace PJ. Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats. Diabetes. 2003 Aug; 52(8):1951-7.
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    48. Makimura H, Mizuno TM, Isoda F, Beasley J, Silverstein JH, Mobbs CV. Role of glucocorticoids in mediating effects of fasting and diabetes on hypothalamic gene expression. BMC Physiol. 2003 Jul 9; 3:5.
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    49. Makimura H, Mizuno TM, Beasley J, Silverstein JH, Mobbs CV. Adrenalectomy stimulates hypothalamic proopiomelanocortin expression but does not correct diet-induced obesity. BMC Physiol. 2003 Jun 9; 3:4.
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    50. Mizuno TM, Makimura H, Mobbs CV. The physiological function of the agouti-related peptide gene: the control of weight and metabolic rate. Ann Med. 2003; 35(6):425-33.
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    51. Makimura H, Mizuno TM, Mastaitis JW, Agami R, Mobbs CV. Reducing hypothalamic AGRP by RNA interference increases metabolic rate and decreases body weight without influencing food intake. BMC Neurosci. 2002 Nov 7; 3:18.
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    52. Wurmbach E, González-Maeso J, Yuen T, Ebersole BJ, Mastaitis JW, Mobbs CV, Sealfon SC. Validated genomic approach to study differentially expressed genes in complex tissues. Neurochem Res. 2002 Oct; 27(10):1027-33.
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    53. Hahm S, Fekete C, Mizuno TM, Windsor J, Yan H, Boozer CN, Lee C, Elmquist JK, Lechan RM, Mobbs CV, Salton SR. VGF is required for obesity induced by diet, gold thioglucose treatment, and agouti and is differentially regulated in pro-opiomelanocortin- and neuropeptide Y-containing arcuate neurons in response to fasting. J Neurosci. 2002 Aug 15; 22(16):6929-38.
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    54. Makimura H, Mizuno TM, Bergen H, Mobbs CV. Adiponectin is stimulated by adrenalectomy in ob/ob mice and is highly correlated with resistin mRNA. Am J Physiol Endocrinol Metab. 2002 Dec; 283(6):E1266-71.
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    55. Mobbs CV, Makimura H. Block the FAS, lose the fat. Nat Med. 2002 Apr; 8(4):335-6.
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    56. Mobbs CV, Kow LM, Yang XJ. Brain glucose-sensing mechanisms: ubiquitous silencing by aglycemia vs. hypothalamic neuroendocrine responses. Am J Physiol Endocrinol Metab. 2001 Oct; 281(4):E649-54.
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    57. Makimura H, Mizuno TM, Yang XJ, Silverstein J, Beasley J, Mobbs CV. Cerulenin mimics effects of leptin on metabolic rate, food intake, and body weight independent of the melanocortin system, but unlike leptin, cerulenin fails to block neuroendocrine effects of fasting. Diabetes. 2001 Apr; 50(4):733-9.
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    58. Mobbs CV, Bray GA, Atkinson RL, Bartke A, Finch CE, Maratos-Flier E, Crawley JN, Nelson JF. Neuroendocrine and pharmacological manipulations to assess how caloric restriction increases life span. J Gerontol A Biol Sci Med Sci. 2001 Mar; 56 Spec No 1:34-44.
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    59. Makimura H, Mizuno TM, Roberts J, Silverstein J, Beasley J, Mobbs CV. Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice. Diabetes. 2000 Nov; 49(11):1917-23.
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    60. Tanaka S, Isoda F, Kiuchi Y, Ikeda H, Mobbs CV, Yamakawa T. T lymphopenia in genetically obese-diabetic Wistar fatty rats: effects of body weight reduction on T cells. Metabolism. 2000 Oct; 49(10):1261-6.
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    61. Funabashi T, Kleopoulos SP, Brooks PJ, Kimura F, Pfaff DW, Shinohara K, Mobbs CV. Changes in estrogenic regulation of estrogen receptor alpha mRNA and progesterone receptor mRNA in the female rat hypothalamus during aging: an in situ hybridization study. Neurosci Res. 2000 Sep; 38(1):85-92.
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    62. Katsel PL, O'Connell B, Mizuno TM, Mobbs CV, Greenstein RJ. Liposome mediated gene transfer into GH3 cells, and rat brain, liver and gut: comparison of different polar or aliphatic domains. Int J Surg Investig. 2000; 1(5):415-29.
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    63. Mobbs C, Mizuno T. Leptin regulation of proopiomelanocortin. Front Horm Res. 2000; 26:57-70.
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    64. Bergen HT, Mizuno T, Taylor J, Mobbs CV. Resistance to diet-induced obesity is associated with increased proopiomelanocortin mRNA and decreased neuropeptide Y mRNA in the hypothalamus. Brain Res. 1999 Dec 18; 851(1-2):198-203.
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    65. Mizuno TM, Makimura H, Silverstein J, Roberts JL, Lopingco T, Mobbs CV. Fasting regulates hypothalamic neuropeptide Y, agouti-related peptide, and proopiomelanocortin in diabetic mice independent of changes in leptin or insulin. Endocrinology. 1999 Oct; 140(10):4551-7.
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    66. Yang XJ, Kow LM, Funabashi T, Mobbs CV. Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms. Diabetes. 1999 Sep; 48(9):1763-72.
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    67. Medina EA, Stanhope KL, Mizuno TM, Mobbs CV, Gregoire F, Hubbard NE, Erickson KL, Havel PJ. Effects of tumor necrosis factor alpha on leptin secretion and gene expression: relationship to changes of glucose metabolism in isolated rat adipocytes. Int J Obes Relat Metab Disord. 1999 Aug; 23(8):896-903.
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    68. Hahm S, Mizuno TM, Wu TJ, Wisor JP, Priest CA, Kozak CA, Boozer CN, Peng B, McEvoy RC, Good P, Kelley KA, Takahashi JS, Pintar JE, Roberts JL, Mobbs CV, Salton SR. Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance. Neuron. 1999 Jul; 23(3):537-48.
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    69. Mizuno TM, Mobbs CV. Hypothalamic agouti-related protein messenger ribonucleic acid is inhibited by leptin and stimulated by fasting. Endocrinology. 1999 Feb; 140(2):814-7.
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    70. Funabashi T, Kleopoulos SP, Kimura F, Mobbs CV. Changes in neurotensin mRNA by estrogen in the female rat preoptic area during aging: an in situ hybridization histochemistry study. Gen Comp Endocrinol. 1998 Dec; 112(3):364-71.
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    71. Bergen HT, Mizuno TM, Taylor J, Mobbs CV. Hyperphagia and weight gain after gold-thioglucose: relation to hypothalamic neuropeptide Y and proopiomelanocortin. Endocrinology. 1998 Nov; 139(11):4483-8.
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    72. Silverstein JH, Beasley J, Mizuno TM, London E, Mobbs CV. Adrenal neuropeptide Y mRNA but not preproenkephalin mRNA induction by stress is impaired by aging in Fischer 344 rats. Mech Ageing Dev. 1998 Apr 1; 101(3):233-43.
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    73. Mueller WM, Gregoire FM, Stanhope KL, Mobbs CV, Mizuno TM, Warden CH, Stern JS, Havel PJ. Evidence that glucose metabolism regulates leptin secretion from cultured rat adipocytes. Endocrinology. 1998 Feb; 139(2):551-8.
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    74. Mizuno TM, Kleopoulos SP, Bergen HT, Roberts JL, Priest CA, Mobbs CV. Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and [corrected] in ob/ob and db/db mice, but is stimulated by leptin. Diabetes. 1998 Feb; 47(2):294-7.
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    75. Brooks PJ, Kleopoulos SP, Funabashi T, Mobbs CV, Pfaff DW. Widespread expression and estrogen regulation of PPEIA-3' nuclear RNA in the rat brain. Proc Natl Acad Sci U S A. 1997 Dec 9; 94(25):14037-41.
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    76. Sugiyama A, Hattori S, Tanaka S, Isoda F, Kleopoulos S, Rosenfeld M, Kaplitt M, Sekihara H, Mobbs C. Defective adenoassociated viral-mediated transfection of insulin gene by direct injection into liver parenchyma decreases blood glucose of diabetic mice. Horm Metab Res. 1997 Dec; 29(12):599-603.
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    77. Mizuno T, Bergen H, Kleopoulos S, Bauman WA, Mobbs CV. Effects of nutritional status and aging on leptin gene expression in mice: importance of glucose. Horm Metab Res. 1996 Dec; 28(12):679-84.
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    78. Bauman WA, Spungen AM, Zhong YG, Mobbs CV. Plasma leptin is directly related to body adiposity in subjects with spinal cord injury. Horm Metab Res. 1996 Dec; 28(12):732-6.
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    79. Bergen HT, Monkman N, Mobbs CV. Injection with gold thioglucose impairs sensitivity to glucose: evidence that glucose-responsive neurons are important for long-term regulation of body weight. Brain Res. 1996 Sep 23; 734(1-2):332-6.
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    80. Mizuno TM, Bergen H, Funabashi T, Kleopoulos SP, Zhong YG, Bauman WA, Mobbs CV. Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity. Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3434-8.
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    81. Bergen HT, Mobbs CV. Ventromedial hypothalamic lesions produced by gold thioglucose do not impair induction of NPY mRNA in the arcuate nucleus by fasting. Brain Res. 1996 Jan 29; 707(2):266-71.
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    82. Funabashi T, Brooks PJ, Kleopoulos SP, Grandison L, Mobbs CV, Pfaff DW. Changes in preproenkephalin messenger RNA level in the rat ventromedial hypothalamus during the estrous cycle. Brain Res Mol Brain Res. 1995 Jan; 28(1):129-34.
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    83. Kaplitt MG, Kwong AD, Kleopoulos SP, Mobbs CV, Rabkin SD, Pfaff DW. Preproenkephalin promoter yields region-specific and long-term expression in adult brain after direct in vivo gene transfer via a defective herpes simplex viral vector. Proc Natl Acad Sci U S A. 1994 Sep 13; 91(19):8979-83.
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    84. Mobbs CV. Molecular hysteresis: residual effects of hormones and glucose on genes during aging. Neurobiol Aging. 1994 Jul-Aug; 15(4):523-34.
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    85. McCarthy MM, Kleopoulos SP, Mobbs CV, Pfaff DW. Infusion of antisense oligodeoxynucleotides to the oxytocin receptor in the ventromedial hypothalamus reduces estrogen-induced sexual receptivity and oxytocin receptor binding in the female rat. Neuroendocrinology. 1994 May; 59(5):432-40.
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    86. Kow LM, Mobbs CV, Pfaff DW. Roles of second-messenger systems and neuronal activity in the regulation of lordosis by neurotransmitters, neuropeptides, and estrogen: a review. Neurosci Biobehav Rev. 1994; 18(2):251-68.
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    87. Brooks PJ, Kaplitt MG, Kleopoulos SP, Funabashi T, Mobbs CV, Pfaff DW. Detection of messenger RNA and low-abundance heteronuclear RNA with single-stranded DNA probes produced by amplified primer extension labeling. J Histochem Cytochem. 1993 Dec; 41(12):1761-6.
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    88. Funabashi T, Brooks PJ, Mobbs CV, Pfaff DW. DNA Methylation and DNase-Hypersensitive Sites in the 5' Flanking and Transcribed Regions of the Rat Preproenkephalin Gene: Studies of Mediobasal Hypothalamus. Mol Cell Neurosci. 1993 Dec; 4(6):499-509.
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    89. Pfaus JG, Kleopoulos SP, Mobbs CV, Gibbs RB, Pfaff DW. Sexual stimulation activates c-fos within estrogen-concentrating regions of the female rat forebrain. Brain Res. 1993 Oct 8; 624(1-2):253-67.
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    90. Kaplitt MG, Kleopoulos SP, Pfaff DW, Mobbs CV. Estrogen increases HIP-70/PLC-alpha messenger ribonucleic acid in the rat uterus and hypothalamus. Endocrinology. 1993 Jul; 133(1):99-104.
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    91. Brooks PJ, Funabashi T, Kleopoulos SP, Mobbs CV, Pfaff DW. Cell-specific expression of preproenkephalin intronic heteronuclear RNA in the rat forebrain. Brain Res Mol Brain Res. 1993 Jul; 19(1-2):22-30.
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    92. Mobbs CV. Genetic influences on glucose neurotoxicity, aging, and diabetes: a possible role for glucose hysteresis. Genetica. 1993; 91(1-3):239-53.
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    93. Olazábal UE, Pfaff DW, Mobbs CV. Sex differences in the regulation of heat shock protein 70 kDa and 90 kDa in the rat ventromedial hypothalamus by estrogen. Brain Res. 1992 Nov 20; 596(1-2):311-4.
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    94. Brooks PJ, Funabashi T, Kleopoulos SP, Mobbs CV, Pfaff DW. Prolactin receptor messenger RNA is synthesized by the epithelial cells of the choroid plexus. Brain Res Mol Brain Res. 1992 Nov; 16(1-2):163-7.
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    95. Olazábal UE, Pfaff DW, Mobbs CV. Estrogenic regulation of heat shock protein 90 kDa in the rat ventromedial hypothalamus and uterus. Mol Cell Endocrinol. 1992 Apr; 84(3):175-83.
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    96. Mobbs CV, Finch CE. Estrogen-induced impairments as a mechanism in reproductive senescence of female C57BL/6J mice. J Gerontol. 1992 Mar; 47(2):B48-51.
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    97. Pfaff DW, Brooks PJ, Funabashi T, Pfaus JG, Mobbs CV. Gene memory in neuroendocrine and behavioural systems. Ciba Found Symp. 1992; 168:165-83; discussion 183-6.
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    98. Lauber AH, Mobbs CV, Muramatsu M, Pfaff DW. Estrogen receptor messenger RNA expression in rat hypothalamus as a function of genetic sex and estrogen dose. Endocrinology. 1991 Dec; 129(6):3180-6.
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    99. Mobbs CV, Kaplitt M, Kow LM, Pfaff DW. PLC-alpha: a common mediator of the action of estrogen and other hormones? Mol Cell Endocrinol. 1991 Sep; 80(1-3):C187-91.
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    100. Romano GJ, Mobbs CV, Lauber A, Howells RD, Pfaff DW. Differential regulation of proenkephalin gene expression by estrogen in the ventromedial hypothalamus of male and female rats: implications for the molecular basis of a sexually differentiated behavior. Brain Res. 1990 Dec 17; 536(1-2):63-8.
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    101. Lauber AH, Romano GJ, Mobbs CV, Pfaff DW. Estradiol Regulation of Estrogen Receptor Messenger Ribonucleic Acid in Rat Mediobasal Hypothalamus: An in situ Hybridization Study. J Neuroendocrinol. 1990 Oct 1; 2(5):605-11.
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    102. Mobbs CV, Fink G, Pfaff DW. HIP-70: an isoform of phosphoinositol-specific phospholipase C-alpha. Science. 1990 Aug 3; 249(4968):566-7.
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    103. Gibbs RB, Mobbs CV, Pfaff DW. Sex steroids and fos expression in rat brain and uterus. Mol Cell Neurosci. 1990 Aug; 1(1):29-40.
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    104. Lauber AH, Romano GJ, Mobbs CV, Howells RD, Pfaff DW. Estradiol induction of proenkephalin messenger RNA in hypothalamus: dose-response and relation to reproductive behavior in the female rat. Brain Res Mol Brain Res. 1990 Jun; 8(1):47-54.
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    105. Mobbs CV, Fink G, Pfaff DW. HIP-70: a protein induced by estrogen in the brain and LH-RH in the pituitary. Science. 1990 Mar 23; 247(4949 Pt 1):1477-9.
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    106. Lustig RH, Mobbs CV, Bradlow HL, McEwen BS, Pfaff DW. Differential effects of estradiol and 16 alpha-hydroxyestrone on pituitary and preoptic estrogen receptor regulation. Endocrinology. 1989 Nov; 125(5):2701-9.
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    107. Mobbs CV, Rothfeld JM, Saluja R, Pfaff DW. Phorbol esters and forskolin infused into midbrain central gray facilitate lordosis. Pharmacol Biochem Behav. 1989 Nov; 34(3):665-7.
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    108. Lustig RH, Mobbs CV, Pfaff DW, Fishman J. Temporal actions of 16 alpha-hydroxyestrone in the rat: comparisons of lordosis dynamics with other estrogen metabolites and between sexes. J Steroid Biochem. 1989 Sep; 33(3):417-21.
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    109. Lustig RH, Pfaff DW, Mobbs CV. Considerations in the quantitative analysis of autoradiograms from 2-dimensional gels. J Neurosci Methods. 1989 Jul; 29(1):17-26.
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    110. Mobbs C, Berman J, Marquardt M, Pfaff D. Comprehensive polypeptide analysis of microdissected rat brain areas: combining 2-dimensional gel electrophoresis with 2-dimensional HPLC and immunoanalysis and sequencing procedures. J Neurosci Methods. 1989 Jul; 29(1):5-15.
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    111. Lustig RH, Pfaff DW, Mobbs CV. Two-dimensional gel autoradiographic analysis of the acute effects of estradiol on protein synthesis in the female rat ventromedial nucleus in vivo. Endocrinology. 1989 Apr; 124(4):1863-9.
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    112. Mobbs C, Fink G, Johnson M, Welch W, Pfaff D. Similarity of an estrogen-induced protein and a luteinizing hormone releasing hormone-induced protein. Mol Cell Endocrinol. 1989 Apr; 62(2):297-306.
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    113. Romano GJ, Mobbs CV, Howells RD, Pfaff DW. Estrogen regulation of proenkephalin gene expression in the ventromedial hypothalamus of the rat: temporal qualities and synergism with progesterone. Brain Res Mol Brain Res. 1989 Jan; 5(1):51-8.
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    114. Gordon MN, Mobbs CV, Finch CE. Pituitary and hypothalamic glucose-6-phosphate dehydrogenase: effects of estradiol and age in C57BL/6J mice. Endocrinology. 1988 Feb; 122(2):726-33.
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    115. Telford N, Mobbs CV, Osterburg HH, Finch CE. Alterations in hypothalamic serotonergic-catecholaminergic relationships in aging C57BL/6J female mice. Exp Gerontol. 1988; 23(6):481-9.
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    116. Mobbs CV, Harlan RE, Burrous MR, Pfaff DW. An estradiol-induced protein synthesized in the ventral medial hypothalamus and transported to the midbrain central gray. J Neurosci. 1988 Jan; 8(1):113-8.
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    117. Telford N, Mobbs CV, Sinha YN, Finch CE. The increase of anterior pituitary dopamine in aging C57BL/6J female mice is caused by ovarian steroids, not intrinsic pituitary aging. Neuroendocrinology. 1986; 43(2):135-42.
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    118. Mobbs CV, Kannegieter LS, Finch CE. Delayed anovulatory syndrome induced by estradiol in female C57BL/6J mice: age-like neuroendocrine, but not ovarian, impairments. Biol Reprod. 1985 Jun; 32(5):1010-7.
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    119. Gordon MN, Mobbs CV, Finch CE. The antiestrogen LY117018 blocks effects of estradiol on pituitary glucose-6-phosphate dehydrogenase specific activity and on serum LH. Neuroendocrinology. 1985 May; 40(5):381-4.
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    120. Mobbs CV, Cheyney D, Sinha YN, Finch CE. Age-correlated and ovary-dependent changes in relationships between plasma estradiol and luteinizing hormone, prolactin, and growth hormone in female C57BL/6J mice. Endocrinology. 1985 Feb; 116(2):813-20.
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    121. Morgan DG, Mobbs CV, Anderson CP, Sinha YN, Finch CE. Hyperprolactinemia fails to increase striatal dopamine receptors in male and female C57BL/6J mice. Eur J Pharmacol. 1984 Dec 15; 107(1):101-4.
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    122. Mobbs CV, Gee DM, Finch CE. Reproductive senescence in female C57BL/6J mice: ovarian impairments and neuroendocrine impairments that are partially reversible and delayable by ovariectomy. Endocrinology. 1984 Nov; 115(5):1653-62.
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    123. Mobbs CV, Flurkey K, Gee DM, Yamamoto K, Sinha YN, Finch CE. Estradiol-induced adult anovulatory syndrome in female C57BL/6J mice: age-like neuroendocrine, but not ovarian, impairments. Biol Reprod. 1984 Apr; 30(3):556-63.
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    124. Gee DM, Flurkey K, Mobbs CV, Sinha YN, Finch CE. The regulation of luteinizing hormone and prolactin in C57BL/6J mice: effects of estradiol implant size, duration of ovariectomy, and aging. Endocrinology. 1984 Mar; 114(3):685-93.
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    125. Finch CE, Felicio LS, Mobbs CV, Nelson JF. Ovarian and steroidal influences on neuroendocrine aging processes in female rodents. Endocr Rev. 1984; 5(4):467-97.
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