Keywords
Last Name
Institution

Adolfo Garcia-Sastre

TitleDIRECTOR Global Health and Emerging Pathogens Institute
InstitutionMount Sinai
Address
    Other Positions
    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentMicrobiology

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentInfectious Diseases


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Perez DR, Garcia-Sastre A. H5N1, a wealth of knowledge to improve pandemic preparedness. Virus Res. 2013 Dec 5; 178(1):1-2.
      View in: PubMed
    2. García-Sastre A. Lessons from lipids in the fight against influenza. Cell. 2013 Jul 3; 154(1):22-3.
      View in: PubMed
    3. Goldstein T, Mena I, Anthony SJ, Medina R, Robinson PW, Greig DJ, Costa DP, Lipkin WI, Garcia-Sastre A, Boyce WM. Pandemic H1N1 influenza isolated from free-ranging Northern Elephant Seals in 2010 off the central California coast. PLoS One. 2013; 8(5):e62259.
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    4. Bentebibel SE, Lopez S, Obermoser G, Schmitt N, Mueller C, Harrod C, Flano E, Mejias A, Albrecht RA, Blankenship D, Xu H, Pascual V, Banchereau J, Garcia-Sastre A, Palucka AK, Ramilo O, Ueno H. Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination. Sci Transl Med. 2013 Mar 13; 5(176):176ra32.
      View in: PubMed
    5. García-Sastre A, Mena I. Novel vaccine strategies against emerging viruses. Curr Opin Virol. 2013 Apr; 3(2):210-6.
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    6. García-Sastre A, Evans MJ. miR-122 is more than a shield for the hepatitis C virus genome. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):1571-2.
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    7. García-Sastre A. The neuraminidase of bat influenza viruses is not a neuraminidase. Proc Natl Acad Sci U S A. 2012 Nov 13; 109(46):18635-6.
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    8. García-Sastre A. Working safely with H5N1 viruses. MBio. 2012; 3(2):e00049-12.
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    9. Bortz E, García-Sastre A. Predicting the pathogenesis of influenza from genomic response: a step toward early diagnosis. Genome Med. 2011; 3(10):67.
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    10. García-Sastre A. Induction and evasion of type I interferon responses by influenza viruses. Virus Res. 2011 Dec; 162(1-2):12-8.
      View in: PubMed
    11. Ye J, Sorrell EM, Cai Y, Shao H, Xu K, Pena L, Hickman D, Song H, Angel M, Medina RA, Manicassamy B, Garcia-Sastre A, Perez DR. Variations in the hemagglutinin of the 2009 H1N1 pandemic virus: potential for strains with altered virulence phenotype? PLoS Pathog. 2010; 6(10):e1001145.
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    12. García-Sastre A. Influenza virus receptor specificity: disease and transmission. Am J Pathol. 2010 Apr; 176(4):1584-5.
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    13. Guo H, Kumar P, Moran TM, Garcia-Sastre A, Zhou Y, Malarkannan S. The functional impairment of natural killer cells during influenza virus infection. Immunol Cell Biol. 2009 Nov-Dec; 87(8):579-89.
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    14. Bolland S, Garcia-Sastre A. Vicious circle: systemic autoreactivity in Ro52/TRIM21-deficient mice. J Exp Med. 2009 Aug 3; 206(8):1647-51.
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    15. Altomonte J, Wu L, Meseck M, Chen L, Ebert O, Garcia-Sastre A, Fallon J, Mandeli J, Woo SL. Enhanced oncolytic potency of vesicular stomatitis virus through vector-mediated inhibition of NK and NKT cells. Cancer Gene Ther. 2009 Mar; 16(3):266-78.
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    16. Squires B, Macken C, Garcia-Sastre A, Godbole S, Noronha J, Hunt V, Chang R, Larsen CN, Klem E, Biersack K, Scheuermann RH. BioHealthBase: informatics support in the elucidation of influenza virus host pathogen interactions and virulence. Nucleic Acids Res. 2008 Jan; 36(Database issue):D497-503.
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    17. Salvatore M, Garcia-Sastre A, Ruchala P, Lehrer RI, Chang T, Klotman ME. alpha-Defensin inhibits influenza virus replication by cell-mediated mechanism(s). J Infect Dis. 2007 Sep 15; 196(6):835-43.
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    18. Legastelois I, Garcia-Sastre A, Palese P, Tumpey TM, Maines TR, Katz JM, Vogel FR, Moste C. Preparation of genetically engineered A/H5N1 and A/H7N1 pandemic vaccine viruses by reverse genetics in a mixture of Vero and chicken embryo cells. Influenza Other Respir Viruses. 2007 May; 1(3):95-104.
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    19. He Q, Martinez-Sobrido L, Eko FO, Palese P, Garcia-Sastre A, Lyn D, Okenu D, Bandea C, Ananaba GA, Black CM, Igietseme JU. Live-attenuated influenza viruses as delivery vectors for Chlamydia vaccines. Immunology. 2007 Sep; 122(1):28-37.
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    20. Garcia-Sastre A, Whitley RJ. Lessons learned from reconstructing the 1918 influenza pandemic. J Infect Dis. 2006 Nov 1; 194 Suppl 2:S127-32.
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    21. Palese P, Tumpey TM, Garcia-Sastre A. What can we learn from reconstructing the extinct 1918 pandemic influenza virus? Immunity. 2006 Feb; 24(2):121-4.
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    22. García-Sastre A. Antiviral response in pandemic influenza viruses. Emerg Infect Dis. 2006 Jan; 12(1):44-7.
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    23. Igietseme J, Eko F, He Q, Bandea C, Lubitz W, Garcia-Sastre A, Black C. Delivery of Chlamydia vaccines. Expert Opin Drug Deliv. 2005 May; 2(3):549-62.
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    24. García-Sastre A. Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses. Curr Top Microbiol Immunol. 2004; 283:249-80.
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    25. Swayne DE, Suarez DL, Schultz-Cherry S, Tumpey TM, King DJ, Nakaya T, Palese P, Garcia-Sastre A. Recombinant paramyxovirus type 1-avian influenza-H7 virus as a vaccine for protection of chickens against influenza and Newcastle disease. Avian Dis. 2003; 47(3 Suppl):1047-50.
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    26. García-Sastre A. Mechanisms of inhibition of the host interferon alpha/beta-mediated antiviral responses by viruses. Microbes Infect. 2002 May; 4(6):647-55.
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    27. Bot A, Shearer M, Bot S, Avriette M, Garcia-Sastre A, White G, Woods C, Kennedy R, Bona C. Induction of immunological memory in baboons primed with DNA vaccine as neonates. Vaccine. 2001 Feb 28; 19(15-16):1960-7.
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    28. García-Sastre A. Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses. Virology. 2001 Jan 20; 279(2):375-84.
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    29. Bergmann M, Garcia-Sastre A, Carnero E, Pehamberger H, Wolff K, Palese P, Muster T. Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication. J Virol. 2000 Jul; 74(13):6203-6.
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    30. Palese P, Muster T, Zheng H, O'Neill R, Garcia-Sastre A. Learning from our foes: a novel vaccine concept for influenza virus. Arch Virol Suppl. 1999; 15:131-8.
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    31. Bot A, Antohi S, Bot S, Garcia-Sastre A, Bona C. Induction of humoral and cellular immunity against influenza virus by immunization of newborn mice with a plasmid bearing a hemagglutinin gene. Int Immunol. 1997 Nov; 9(11):1641-50.
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    32. Gilleland HE, Gilleland LB, Staczek J, Harty RN, Garcia-Sastre A, Engelhardt OG, Palese P. Chimeric influenza viruses incorporating epitopes of outer membrane protein F as a vaccine against pulmonary infection with Pseudomonas aeruginosa. Behring Inst Mitt. 1997 Feb; (98):291-301.
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    33. Bot A, Bot S, Garcia-Sastre A, Bona C. DNA immunization of newborn mice with a plasmid-expressing nucleoprotein of influenza virus. Viral Immunol. 1996; 9(4):207-10.
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    34. Rodrigues M, Li S, Murata K, Rodriguez D, Rodriguez JR, Bacik I, Bennink JR, Yewdell JW, Garcia-Sastre A, Nussenzweig RS, et al. Influenza and vaccinia viruses expressing malaria CD8+ T and B cell epitopes. Comparison of their immunogenicity and capacity to induce protective immunity. J Immunol. 1994 Nov 15; 153(10):4636-48.
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    35. Garcia Pascual JJ, Villar E, Corrales JJ, Garcia-Sastre A, Garcia-Diez LC, Corral J, Cabezas JA, Miralles JM. Enzymatic glycosidase activities in experimental obesity. Horm Metab Res. 1992 Sep; 24(9):412-5.
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    36. Luo G, Bergmann M, Garcia-Sastre A, Palese P. Mechanism of attenuation of a chimeric influenza A/B transfectant virus. J Virol. 1992 Aug; 66(8):4679-85.
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    37. Garcia-Sastre A, Villar E, Manuguerra JC, Hannoun C, Cabezas JA. Activity of influenza C virus O-acetylesterase with O-acetyl-containing compounds. Biochem J. 1991 Jan 15; 273(Pt 2):435-41.
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    38. Garcia-Sastre A, Villar E, Hannoun C, Cabezas JA. Sialidase activity in rimantadine-resistant and -sensitive influenza A viruses. Enzyme. 1990; 43(4):207-11.
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    39. Fiszon B, Hannoun C, Garcia-Sastre A, Villar E, Cabezas JA. Comparison of biological and physical properties of human and animal A(H1N1) influenza viruses. Res Virol. 1989 Sep-Oct; 140(5):395-404.
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