Keywords
Last Name
Institution

Karen Zier

TitlePROFESSOR
InstitutionMount Sinai
DepartmentClinical Immunology
Address
    Other Positions
    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentOncological Sciences

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentMicrobiology

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentMedical Education

    TitleASSOCIATE DEAN FOR MEDICAL STUDENT RESEARCH
    InstitutionMount Sinai


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Zier K, Wyatt C, Muller D. An innovative portfolio of research training programs for medical students. Immunol Res. 2012 Dec; 54(1-3):286-91.
      View in: PubMed
    2. Zier K, Coplit LD. Introducing INSPIRE, a scholarly component in undergraduate medical education. Mt Sinai J Med. 2009 Aug; 76(4):387-91.
      View in: PubMed
    3. Cohen BL, Friedman E, Zier K. Publications by students doing a year of full-time research: what are realistic expectations? Am J Med. 2008 Jun; 121(6):545-8.
      View in: PubMed
    4. Zier K, Friedman E, Smith L. Supportive programs increase medical students' research interest and productivity. J Investig Med. 2006 May; 54(4):201-7.
      View in: PubMed
    5. Bartido SM, Zier K. T-cell responses to multiple antigens presented by RNA-transfected APCs: a possible immunomonitoring tool. Cancer Immunol Immunother. 2004 Feb; 53(2):100-9.
      View in: PubMed
    6. Zier K, Stagnaro-Green A. A multifaceted program to encourage medical students' research. Acad Med. 2001 Jul; 76(7):743-7.
      View in: PubMed
    7. Zier KS, Salvadori S. Generation of anti-allogeneic cytotoxic T lymphocytes depends upon a signal, not delivered by tumor cells, that can be provided in trans in the presence of exogenous interleukin-2. Cancer Immunol Immunother. 1999 Aug; 48(5):247-52.
      View in: PubMed
    8. Zier KS, Gansbacher B. Tumour cell vaccines that secrete interleukin-2 (IL-2) and interferon gamma (IFN gamma) are recognised by T cells while resisting destruction by natural killer (NK) cells. Eur J Cancer. 1996 Jul; 32A(8):1408-12.
      View in: PubMed
    9. Zier KS, Gansbacher B. IL-2 gene therapy of solid tumors: an approach for the prevention of signal transduction defects in T cells. J Mol Med (Berl). 1996 Mar; 74(3):127-34.
      View in: PubMed
    10. Zier KS, Gansbacher B. The impact of gene therapy on T cell function in cancer. Hum Gene Ther. 1995 Oct; 6(10):1259-64.
      View in: PubMed
    11. Salvadori S, Gansbacher B, Pizzimenti AM, Zier KS. Abnormal signal transduction by T cells of mice with parental tumors is not seen in mice bearing IL-2-secreting tumors. J Immunol. 1994 Dec 1; 153(11):5176-82.
      View in: PubMed
    12. Rosenthal FM, Zier KS, Gansbacher B. Human tumor vaccines and genetic engineering of tumors with cytokine and histocompatibility genes to enhance immunogenicity. Curr Opin Oncol. 1994 Nov; 6(6):611-5.
      View in: PubMed
    13. Zier KS, Salvadori S, Cronin KC, Gansbacher B. Vaccination with IL-2-secreting tumor cells stimulates the generation of IL-2-responsive T cells and prevents the development of unresponsiveness. Cancer Gene Ther. 1994 Mar; 1(1):43-50.
      View in: PubMed
    14. Salvadori S, Rosenthal FM, Cronin K, Gansbacher B, Zier KS. Tumor-bearing animals contain suppressed antitumor effectors the function of which can be unmasked by IL-2. J Immunother Emphasis Tumor Immunol. 1993 Oct; 14(3):216-20.
      View in: PubMed
    15. Caplen HS, Salvadori S, Gansbacher B, Zier KS. Post-transcriptional regulation of MHC class II expression in human T cells. Cell Immunol. 1992 Jan; 139(1):98-107.
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    16. Salvadori S, Pizzimenti A, Cohen S, Zier KS. The control of class II expression on T cells is independent of the regulation of Tac and the induction of proliferation. Clin Exp Immunol. 1991 Dec; 86(3):544-9.
      View in: PubMed
    17. Shah U, Cutilli JR, Zier KS. The response pattern of human T cells to stimulation following expansion in IL-2. Immunol Invest. 1991 Dec; 20(7):629-43.
      View in: PubMed
    18. Shah U, Karch L, Baker L, Zier KS. Low interleukin-2 synthesis by type 1 diabetics is regulated at the pretranslational level. Clin Immunol Immunopathol. 1991 Nov; 61(2 Pt 1):177-90.
      View in: PubMed
    19. Urban ND, Zier KS. Negative signal transmission through class II molecules on activated T cells. Hum Immunol. 1991 Jul; 31(3):170-9.
      View in: PubMed
    20. Zier KS, Pierson GR, Brown V. Susceptibility of human neuroblastoma cell lines to cytotoxic T lymphocyte-mediated lysis. J Neuroimmunol. 1990 Jul; 28(2):153-60.
      View in: PubMed
    21. Pierson GR, Evans AE, Zier KS. The development of cell mediated immunity: very young children have strong LAK activity. J Clin Lab Immunol. 1990 Feb; 31(2):51-4.
      View in: PubMed
    22. Gansbacher B, Zier KS. HLA class II mRNA accumulation by activated human T cells following growth in conditioned medium. Clin Exp Immunol. 1989 Jun; 76(3):440-5.
      View in: PubMed
    23. Gansbacher B, Zier KS. Regulation of HLA-DR, DP, and DQ expression in activated T cells. Cell Immunol. 1988 Nov; 117(1):22-34.
      View in: PubMed
    24. Zier KS, Volsky DJ, Sinangil F. The detection of human minor alloantigens following restriction determinant implantation. Hum Immunol. 1987 May; 19(1):17-27.
      View in: PubMed
    25. Zier KS. Expression of class II antigens by subsets of activated T cells. Cell Immunol. 1986 Jul; 100(2):525-31.
      View in: PubMed
    26. Zier KS. Generation of antigen specific cytotoxic T lymphocytes (CTL) directed against class II molecules expressed by activated T cells. J Immunol Methods. 1985 Nov 28; 84(1-2):73-84.
      View in: PubMed
    27. Zier KS, Pickard AR. Presentation of Class I antigens on T cells can induce the generation of antigen-specific CTL. J Immunol. 1985 Oct; 135(4):2274-8.
      View in: PubMed
    28. Zier KS. Proliferative T cell clones directed at a human minor antigen. Exp Clin Immunogenet. 1985; 2(1):36-42.
      View in: PubMed
    29. Zier KS, Israel LJ. Generation of CTL lines using cultured T cells (CTC) as feeder cells. I. Specificity for class I determinants. Hum Immunol. 1984 Sep; 11(1):47-55.
      View in: PubMed
    30. Zier KS, Leo MM, Spielman RS, Baker L. Decreased synthesis of interleukin-2 (IL-2) in insulin-dependent diabetes mellitus. Diabetes. 1984 Jun; 33(6):552-5.
      View in: PubMed
    31. Zier KS, Zmijewski CM. The serological definition of polymorphic HLA-D region gene products on cultured T cells. Detection of DR and MT antigens. Transplantation. 1984 May; 37(5):514-7.
      View in: PubMed
    32. Zier KS, Elkins WL, Pierson GR, Leo MM. The use of cytotoxic T cell lines to detect the segregation of a human minor alloantigen within families. Hum Immunol. 1983 Jul; 7(3):117-29.
      View in: PubMed
    33. Zier KS. Functional and antigenic properties of cultured T cells in the cell mediated lympholysis (CML) assay. Hum Immunol. 1982 Apr; 4(2):147-56.
      View in: PubMed
    34. Zier KS, Elkins WL, Pierson GR. Cytotoxic T lymphocyte lines (CTLL) against a human minor alloantigen. Immunogenetics. 1982; 15(5):501-8.
      View in: PubMed
    35. Elkins WL, Pierson G, Negendank W, Zier KS. Recognition of human minor alloantigen(s) by cytotoxic lymphocytes in vitro. Immunogenetics. 1982; 15(5):485-99.
      View in: PubMed
    36. Zier KS, Gansbacher B. Generation of discriminatory PL against HLA-D antigens not detected by serology. Hum Immunol. 1981 Aug; 3(1):57-65.
      View in: PubMed
    37. Zier KS, Gansbacher B, Scholz S, Albert E. Behavior of HLA-DR homozygous cells in MLC and PLT. Transplant Proc. 1981 Mar; 13(1 Pt 2):1035-8.
      View in: PubMed
    38. Zier KS, Huber C, Albert E, Braunsteiner H. Cell-mediated immune responses between HLA-identical siblings: recognition of antigenic changes associated with acute myelogenous leukaemia. Clin Exp Immunol. 1980 Apr; 40(1):136-46.
      View in: PubMed
    39. Zier KS, Gänsbacher B, Scholz S, Albert ED. Heterogeneity of HLA defined in PLT: a cellular assay detects differences not seen using HLA-DRw serology. Immunogenetics. 1980; 10(6):513-20.
      View in: PubMed
    40. Zier KS, Huber C, Braunsteiner H. Linear density gradient separation of human lymphocyte subsets. II. Characterization of cells responding in secondary MLC and CML. Cell Immunol. 1979 Jul; 45(2):325-33.
      View in: PubMed
    41. Zier KS, Scholz S, Albert ED. Crossreactivity in PLT: the specificity of primed lymphocytes (PL) depends upon the HLA haplotypes of the priming cell and responder. Transplant Proc. 1979 Mar; 11(1):723-6.
      View in: PubMed
    42. Zier KS, Huber C, Braunsteiner H. Restimulation in secondary MLC by autologous non-T cells. Scand J Immunol. 1979; 9(6):493-8.
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    43. Zier KS, Huber C, Braunsteiner H. Linear density gradient separation of human lymphocyte subsets. I. Analysis by mixed leukocyte culture and cell-mediated lympholysis responses. Eur J Immunol. 1977 Jun; 7(6):366-70.
      View in: PubMed
    44. Alter BJ, Grillot-Courvalin C, Bach ML, Zier KS, Sondel PM, Bach FH. Secondary cell-mediated lympholysis: importance of H-2 LD and SD factors. J Exp Med. 1976 May 1; 143(5):1005-14.
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    45. Zier KS, Bach FH. Secondary responses of human lymphocytes to alloantigens in vitro. Scand J Immunol. 1975 Sep; 4(5-6):607-11.
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    46. Bach FH, Zier KS, Sondel PM. The nature of cells responding in mixed leukocyte cultures and cell-mediated lympholysis. Transplant Proc. 1973 Dec; 5(4):1717-20.
      View in: PubMed
    47. Bach FH, Segall M, Zier KS, Sondel PM, Alter BJ, Bach ML. Cell mediated immunity: separation of cells involved in recognitive and destructive phases. Science. 1973 Apr 27; 180(4084):403-6.
      View in: PubMed
    48. Segall M, Schendel DJ, Zier KS. MLC workshop summary report. Tissue Antigens. 1973; 3(5):353-7.
      View in: PubMed
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