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Institution

Kevin A. Kelley

TitleRESEARCH PROFESSOR
InstitutionMount Sinai
DepartmentDevelopmental and Regenerative Biology
Address
    Other Positions
    TitleASSOCIATE PROFESSOR
    InstitutionMount Sinai
    DepartmentNeuroscience


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Shalata A, Ramirez MC, Desnick RJ, Priedigkeit N, Buettner C, Lindtner C, Mahroum M, Abdul-Ghani M, Dong F, Arar N, Camacho-Vanegas O, Zhang R, Camacho SC, Chen Y, Ibdah M, Defronzo R, Gillespie V, Kelley K, Dynlacht BD, Kim S, Glucksman MJ, Borochowitz ZU, Martignetti JA. Morbid Obesity Resulting from Inactivation of the Ciliary Protein CEP19 in Humans and Mice. Am J Hum Genet. 2013 Dec 5; 93(6):1061-71.
      View in: PubMed
    2. Kelley K, Berberich SJ. FHIT gene expression is repressed by mitogenic signaling through the PI3K/AKT/FOXO pathway. Am J Cancer Res. 2011; 1(1):62-70.
      View in: PubMed
    3. Giza J, Urbanski MJ, Prestori F, Bandyopadhyay B, Yam A, Friedrich V, Kelley K, D'Angelo E, Goldfarb M. Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2. J Neurosci. 2010 Nov 3; 30(44):14805-16.
      View in: PubMed
    4. Au AC, Hernandez PA, Lieber E, Nadroo AM, Shen YM, Kelley KA, Gelb BD, Diaz GA. Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humans. Am J Hum Genet. 2010 Sep 10; 87(3):436-44.
      View in: PubMed
    5. Tsai SY, Clavel C, Kim S, Ang YS, Grisanti L, Lee DF, Kelley K, Rendl M. Oct4 and klf4 reprogram dermal papilla cells into induced pluripotent stem cells. Stem Cells. 2010 Feb; 28(2):221-8.
      View in: PubMed
    6. Kelley KA. Enhancement of IVF in the mouse by zona-drilling. Methods Enzymol. 2010; 476:229-50.
      View in: PubMed
    7. Kelley KA. Transport of mouse lines by shipment of live embryos. Methods Enzymol. 2010; 476:25-36.
      View in: PubMed
    8. Field HA, Kelley KA, Martell L, Goldstein AM, Serluca FC. Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish. Neurogastroenterol Motil. 2009 Mar; 21(3):304-12.
      View in: PubMed
    9. Goldfarb M, Schoorlemmer J, Williams A, Diwakar S, Wang Q, Huang X, Giza J, Tchetchik D, Kelley K, Vega A, Matthews G, Rossi P, Ornitz DM, D'Angelo E. Fibroblast growth factor homologous factors control neuronal excitability through modulation of voltage-gated sodium channels. Neuron. 2007 Aug 2; 55(3):449-63.
      View in: PubMed
    10. Narla G, Kremer-Tal S, Matsumoto N, Zhao X, Yao S, Kelley K, Tarocchi M, Friedman SL. In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma. Oncogene. 2007 Jun 28; 26(30):4428-34.
      View in: PubMed
    11. Nicolas N, Marazzi G, Kelley K, Sassoon D. Embryonic deregulation of muscle stress signaling pathways leads to altered postnatal stem cell behavior and a failure in postnatal muscle growth. Dev Biol. 2005 May 15; 281(2):171-83.
      View in: PubMed
    12. Jensen KK, Manfra DJ, Grisotto MG, Martin AP, Vassileva G, Kelley K, Schwartz TW, Lira SA. The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma. J Immunol. 2005 Mar 15; 174(6):3686-94.
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    13. De Gasperi R, Friedrich VL, Perez GM, Senturk E, Wen PH, Kelley K, Elder GA, Gama Sosa MA. Transgenic rescue of Krabbe disease in the twitcher mouse. Gene Ther. 2004 Aug; 11(15):1188-94.
      View in: PubMed
    14. Gama Sosa MA, Friedrich VL, DeGasperi R, Kelley K, Wen PH, Senturk E, Lazzarini RA, Elder GA. Human midsized neurofilament subunit induces motor neuron disease in transgenic mice. Exp Neurol. 2003 Nov; 184(1):408-19.
      View in: PubMed
    15. Mizuno TM, Kelley KA, Pasinetti GM, Roberts JL, Mobbs CV. Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese mice. Diabetes. 2003 Nov; 52(11):2675-83.
      View in: PubMed
    16. Stecca B, Nait-Oumesmar B, Kelley KA, Voss AK, Thomas T, Lazzarini RA. Gcm1 expression defines three stages of chorio-allantoic interaction during placental development. Mech Dev. 2002 Jul; 115(1-2):27-34.
      View in: PubMed
    17. Gama SM, De Gasperi R, Wen PH, Gonzalez EA, Kelley K, Lazzarini RA, Elder GA. BAC and PAC DNA for the generation of transgenic animals. Biotechniques. 2002 Jul; 33(1):51-3.
      View in: PubMed
    18. Wen PH, Shao X, Shao Z, Hof PR, Wisniewski T, Kelley K, Friedrich VL, Ho L, Pasinetti GM, Shioi J, Robakis NK, Elder GA. Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice. Neurobiol Dis. 2002 Jun; 10(1):8-19.
      View in: PubMed
    19. Xiang Z, Ho L, Valdellon J, Borchelt D, Kelley K, Spielman L, Aisen PS, Pasinetti GM. Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology. Neurobiol Aging. 2002 May-Jun; 23(3):327-34.
      View in: PubMed
    20. Xiang Z, Ho L, Yemul S, Zhao Z, Qing W, Pompl P, Kelley K, Dang A, Qing W, Teplow D, Pasinetti GM. Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology. Gene Expr. 2002; 10(5-6):271-8.
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    21. Barlow JZ, Kelley KA, Bozdagi O, Huntley GW. Testing the role of the cell-surface molecule Thy-1 in regeneration and plasticity of connectivity in the CNS. Neuroscience. 2002; 111(4):837-52.
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    22. Stecca B, Southwood CM, Gragerov A, Kelley KA, Friedrich VL, Gow A. The evolution of lipophilin genes from invertebrates to tetrapods: DM-20 cannot replace proteolipid protein in CNS myelin. J Neurosci. 2000 Jun 1; 20(11):4002-10.
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    23. Kelley KA, Ho L, Winger D, Freire-Moar J, Borelli CB, Aisen PS, Pasinetti GM. Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2. Am J Pathol. 1999 Sep; 155(3):995-1004.
      View in: PubMed
    24. Hahm S, Mizuno TM, Wu TJ, Wisor JP, Priest CA, Kozak CA, Boozer CN, Peng B, McEvoy RC, Good P, Kelley KA, Takahashi JS, Pintar JE, Roberts JL, Mobbs CV, Salton SR. Targeted deletion of the Vgf gene indicates that the encoded secretory peptide precursor plays a novel role in the regulation of energy balance. Neuron. 1999 Jul; 23(3):537-48.
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    25. Dracheva S, Xu M, Kelley KA, Haroutunian V, Holstein GR, Haun S, Silverstein JH, Sealfon SC. Paradoxical locomotor behavior of dopamine D1 receptor transgenic mice. Exp Neurol. 1999 May; 157(1):169-79.
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    26. Siegel H, Kelley K, Stertz B, Reeves-Tyer P, Flamini R, Malow B, Gaillard WD, Ko D, Theodore WH. The efficacy of felbamate as add-on therapy to valproic acid in the Lennox-Gastaut syndrome. Epilepsy Res. 1999 Apr; 34(2-3):91-7.
      View in: PubMed
    27. Buggy JJ, Heurich RO, MacDougall M, Kelley KA, Livingston JN, Yoo-Warren H, Rossomando AJ. Role of the glucagon receptor COOH-terminal domain in glucagon-mediated signaling and receptor internalization. Diabetes. 1997 Sep; 46(9):1400-5.
      View in: PubMed
    28. Kelley KA, Friedrich VL, Sonshine A, Hu Y, Lax J, Li J, Drinkwater D, Dressler H, Herrup K. Expression of Thy-1/lacZ fusion genes in the CNS of transgenic mice. Brain Res Mol Brain Res. 1994 Jul; 24(1-4):261-74.
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    29. Rothman BL, Kennure N, Kelley KA, Katz M, Aune TM. Elevation of intracellular cAMP in human T lymphocytes by an anti-CD44 mAb. J Immunol. 1993 Dec 1; 151(11):6036-42.
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    30. Friedrich VL, Holstein GR, Li X, Gow A, Kelley KA, Lazzarini RA. Intracellular distribution of transgenic bacterial beta-galactosidase in central nervous system neurons and neuroglia. J Neurosci Res. 1993 Sep 1; 36(1):88-98.
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    31. Aune TM, McGrath KM, Sarr T, Bombara MP, Kelley KA. Expression of 5HT1a receptors on activated human T cells. Regulation of cyclic AMP levels and T cell proliferation by 5-hydroxytryptamine. J Immunol. 1993 Aug 1; 151(3):1175-83.
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    32. Gerritsen ME, Kelley KA, Ligon G, Perry CA, Shen CP, Szczepanski A, Carley WW. Regulation of the expression of intercellular adhesion molecule 1 in cultured human endothelial cells derived from rheumatoid synovium. Arthritis Rheum. 1993 May; 36(5):593-602.
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    33. Conrad P, Rothman BL, Kelley KA, Blue ML. Mechanism of peripheral T cell activation by coengagement of CD44 and CD2. J Immunol. 1992 Sep 15; 149(6):1833-9.
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    34. Kelley KA, Stamm S, Kozak CA. Expression and chromosome localization of the murine cystic fibrosis transmembrane conductance regulator. Genomics. 1992 Jun; 13(2):381-8.
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    35. Rothman BL, Blue ML, Kelley KA, Wunderlich D, Mierz DV, Aune TM. Human T cell activation by OKT3 is inhibited by a monoclonal antibody to CD44. J Immunol. 1991 Oct 15; 147(8):2493-9.
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    36. Kelley KA, Agarwal N, Reeders S, Herrup K. Renal cyst formation and multifocal neoplasia in transgenic mice carrying the simian virus 40 early region. J Am Soc Nephrol. 1991 Jul; 2(1):84-97.
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    37. Aune TM, Kelley KA, Ranges GE, Bombara MP. Serotonin-activated signal transduction via serotonin receptors on Jurkat cells. J Immunol. 1990 Sep 15; 145(6):1826-31.
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    38. Raj NB, Israeli R, Kelley KA, Leach SJ, Minasian E, Sikaris K, Parry DA, Pitha PM. Synthesis, antiviral activity, and conformational characterization of mouse-human alpha-interferon hybrids. J Biol Chem. 1988 Jun 25; 263(18):8943-52.
      View in: PubMed
    39. Kelley KA, Chamberlain JW, Nolan JA, Horwich AL, Kalousek F, Eisenstadt J, Herrup K, Rosenberg LE. Meiotic expression of human ornithine transcarbamylase in the testes of transgenic mice. Mol Cell Biol. 1988 Apr; 8(4):1821-5.
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    40. Chamberlain JW, Nolan JA, Gromkowski SH, Kelley KA, Eisenstadt JM, Herrup K, Janeway CA, Weissman SM. Cell surface expression and alloantigenic function of a human class I MHC heavy chain gene (HLA-B7) in transgenic mice. J Immunol. 1988 Feb 15; 140(4):1285-92.
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    41. Nadeau JH, Berger FG, Kelley KA, Pitha PM, Sidman CL, Worrall N. Rearrangement of genes located on homologous chromosomal segments in mouse and man: the location of genes for alpha- and beta-interferon, alpha-1 acid glycoprotein-1 and -2, and aminolevulinate dehydratase on mouse chromosome 4. Genetics. 1986 Dec; 114(4):1239-55.
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    42. Kelley KA, Pitha PM, Demaeyer-Guignard J, Demaeyer E, Kozak C. Assignment of two mouse genes coinduced with interferon to chromosomes 12 and X. J Interferon Res. 1986 Feb; 6(1):51-7.
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    43. Kelley KA, Raj NB, Kellum M, Pitha PM. Synthesis of fusion and mature murine alpha interferons in Escherichia coli. Gene. 1986; 45(3):317-25.
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    44. Kelley KA, Pitha PM. Differential effect of poly rI.rC and Newcastle disease virus on the expression of interferon and cellular genes in mouse cells. Virology. 1985 Dec; 147(2):382-93.
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    45. Kelley KA, Pitha PM. Characterization of a mouse interferon gene locus II. Differential expression of alpha-interferon genes. Nucleic Acids Res. 1985 Feb 11; 13(3):825-39.
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    46. Kelley KA, Kozak CA, Pitha PM. Localization of the mouse interferon-beta 1 gene to chromosome 4. J Interferon Res. 1985; 5(3):409-13.
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    47. Kelley KA, Kozak CA, Dandoy F, Sor F, Skup D, Windass JD, DeMaeyer-Guignard J, Pitha PM, DeMaeyer E. Mapping of murine interferon-alpha genes to chromosome 4. Gene. 1983 Dec; 26(2-3):181-8.
      View in: PubMed
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067