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Peter Tessier

TitleAssociate Professor
InstitutionRensselaer Polytechnic Institute
DepartmentChemical and Biological Engineering
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Li X, Zhang X, Ladiwala AR, Du D, Yadav JK, Tessier PM, Wright PE, Kelly JW, Buxbaum JN. Mechanisms of Transthyretin Inhibition of ß-Amyloid Aggregation In Vitro. J Neurosci. 2013 Dec 11; 33(50):19423-33.
      View in: PubMed
    2. Andersson EK, Bengtsson C, Evans ML, Chorell E, Sellstedt M, Lindgren AE, Hufnagel DA, Bhattacharya M, Tessier PM, Wittung-Stafshede P, Almqvist F, Chapman MR. Modulation of curli assembly and pellicle biofilm formation by chemical and protein chaperones. Chem Biol. 2013 Oct 24; 20(10):1245-54.
      View in: PubMed
    3. Lee CC, Perchiacca JM, Tessier PM. Toward aggregation-resistant antibodies by design. Trends Biotechnol. 2013 Nov; 31(11):612-20.
      View in: PubMed
    4. Tiller KE, Tessier PM. Lifting the veil on amyloid drug design. Elife. 2013; 2:e01089.
      View in: PubMed
    5. Sule SV, Dickinson CD, Lu J, Chow CK, Tessier PM. Rapid analysis of antibody self-association in complex mixtures using immunogold conjugates. Mol Pharm. 2013 Apr 1; 10(4):1322-31.
      View in: PubMed
    6. Ladiwala AR, Bhattacharya M, Perchiacca JM, Cao P, Raleigh DP, Abedini A, Schmidt AM, Varkey J, Langen R, Tessier PM. Rational design of potent domain antibody inhibitors of amyloid fibril assembly. Proc Natl Acad Sci U S A. 2012 Dec 4; 109(49):19965-70.
      View in: PubMed
    7. Perchiacca JM, Ladiwala AR, Bhattacharya M, Tessier PM. Aggregation-resistant domain antibodies engineered with charged mutations near the edges of the complementarity-determining regions. Protein Eng Des Sel. 2012 Oct; 25(10):591-601.
      View in: PubMed
    8. Ladiwala AR, Litt J, Kane RS, Aucoin DS, Smith SO, Ranjan S, Davis J, Van Nostrand WE, Tessier PM. Conformational differences between two amyloid ß oligomers of similar size and dissimilar toxicity. J Biol Chem. 2012 Jul 13; 287(29):24765-73.
      View in: PubMed
    9. Perchiacca JM, Tessier PM. Engineering aggregation-resistant antibodies. Annu Rev Chem Biomol Eng. 2012; 3:263-86.
      View in: PubMed
    10. Ladiwala AR, Perchiacca JM, Fishman ZS, Bhattacharya M, Hickey AM, Domigan BG, Dordick JS, Tessier PM. Polyphenolic disaccharides endow proteins with unusual resistance to aggregation. Biotechnol Bioeng. 2012 Jul; 109(7):1869-74.
      View in: PubMed
    11. Sule SV, Cheung JK, Antochshuk V, Bhalla AS, Narasimhan C, Blaisdell S, Shameem M, Tessier PM. Solution pH that minimizes self-association of three monoclonal antibodies is strongly dependent on ionic strength. Mol Pharm. 2012 Apr 2; 9(4):744-51.
      View in: PubMed
    12. Perchiacca JM, Ladiwala AR, Bhattacharya M, Tessier PM. Structure-based design of conformation- and sequence-specific antibodies against amyloid ß. Proc Natl Acad Sci U S A. 2012 Jan 3; 109(1):84-9.
      View in: PubMed
    13. Posada D, Tessier PM, Hirsa AH. Removal versus fragmentation of amyloid-forming precursors via membrane filtration. Biotechnol Bioeng. 2012 Mar; 109(3):840-5.
      View in: PubMed
    14. Sule SV, Sukumar M, Weiss WF, Marcelino-Cruz AM, Sample T, Tessier PM. High-throughput analysis of concentration-dependent antibody self-association. Biophys J. 2011 Oct 5; 101(7):1749-57.
      View in: PubMed
    15. Perchiacca JM, Bhattacharya M, Tessier PM. Mutational analysis of domain antibodies reveals aggregation hotspots within and near the complementarity determining regions. Proteins. 2011 Sep; 79(9):2637-47.
      View in: PubMed
    16. Marcelino-Cruz AM, Bhattacharya M, Anselmo AC, Tessier PM. Site-specific structural analysis of a yeast prion strain with species-specific seeding activity. Prion. 2011 Jul-Sep; 5(3):208-14.
      View in: PubMed
    17. Ladiwala AR, Mora-Pale M, Lin JC, Bale SS, Fishman ZS, Dordick JS, Tessier PM. Polyphenolic glycosides and aglycones utilize opposing pathways to selectively remodel and inactivate toxic oligomers of amyloid ß. Chembiochem. 2011 Jul 25; 12(11):1749-58.
      View in: PubMed
    18. Ladiwala AR, Dordick JS, Tessier PM. Aromatic small molecules remodel toxic soluble oligomers of amyloid beta through three independent pathways. J Biol Chem. 2011 Feb 4; 286(5):3209-18.
      View in: PubMed
    19. Ladiwala AR, Lin JC, Bale SS, Marcelino-Cruz AM, Bhattacharya M, Dordick JS, Tessier PM. Resveratrol selectively remodels soluble oligomers and fibrils of amyloid Abeta into off-pathway conformers. J Biol Chem. 2010 Jul 30; 285(31):24228-37.
      View in: PubMed
    20. Bengali AN, Tessier PM. Biospecific protein immobilization for rapid analysis of weak protein interactions using self-interaction nanoparticle spectroscopy. Biotechnol Bioeng. 2009 Oct 1; 104(2):240-50.
      View in: PubMed
    21. Tessier PM, Lindquist S. Unraveling infectious structures, strain variants and species barriers for the yeast prion [PSI+]. Nat Struct Mol Biol. 2009 Jun; 16(6):598-605.
      View in: PubMed
    22. Tessier PM, Jinkoji J, Cheng YC, Prentice JL, Lenhoff AM. Self-interaction nanoparticle spectroscopy: a nanoparticle-based protein interaction assay. J Am Chem Soc. 2008 Mar 12; 130(10):3106-12.
      View in: PubMed
    23. Tessier PM, Lindquist S. Prion recognition elements govern nucleation, strain specificity and species barriers. Nature. 2007 May 31; 447(7144):556-61.
      View in: PubMed
    24. Tessier PM, Verruto VJ, Sandler SI, Lenhoff AM. Correlation of diafiltration sieving behavior of lysozyme-BSA mixtures with osmotic second virial cross-coefficients. Biotechnol Bioeng. 2004 Aug 5; 87(3):303-10.
      View in: PubMed
    25. Tessier PM, Sandler SI, Lenhoff AM. Direct measurement of protein osmotic second virial cross coefficients by cross-interaction chromatography. Protein Sci. 2004 May; 13(5):1379-90.
      View in: PubMed
    26. Tessier PM, Lenhoff AM. Measurements of protein self-association as a guide to crystallization. Curr Opin Biotechnol. 2003 Oct; 14(5):512-6.
      View in: PubMed
    27. Tessier PM, Johnson HR, Pazhianur R, Berger BW, Prentice JL, Bahnson BJ, Sandler SI, Lenhoff AM. Predictive crystallization of ribonuclease A via rapid screening of osmotic second virial coefficients. Proteins. 2003 Feb 1; 50(2):303-11.
      View in: PubMed
    28. Tessier PM, Vandrey SD, Berger BW, Pazhianur R, Sandler SI, Lenhoff AM. Self-interaction chromatography: a novel screening method for rational protein crystallization. Acta Crystallogr D Biol Crystallogr. 2002 Oct; 58(Pt 10 Pt 1):1531-5.
      View in: PubMed
    29. Tessier PM, Lenhoff AM, Sandler SI. Rapid measurement of protein osmotic second virial coefficients by self-interaction chromatography. Biophys J. 2002 Mar; 82(3):1620-31.
      View in: PubMed
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067