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Last Name
Institution

Patrick Maxwell

TitleAssistant Professor
InstitutionRensselaer Polytechnic Institute
DepartmentBiology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Yang OC, Maxwell PH, Pollard PJ. Renal cell carcinoma: translational aspects of metabolism and therapeutic consequences. Kidney Int. 2013 Oct; 84(4):667-81.
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    2. Barriga EH, Maxwell PH, Reyes AE, Mayor R. The hypoxia factor Hif-1a controls neural crest chemotaxis and epithelial to mesenchymal transition. J Cell Biol. 2013 May 27; 201(5):759-76.
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    3. Zhao H, Watts HR, Chong M, Huang H, Tralau-Stewart C, Maxwell PH, Maze M, George AJ, Ma D. Xenon treatment protects against cold ischemia associated delayed graft function and prolongs graft survival in rats. Am J Transplant. 2013 Aug; 13(8):2006-18.
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    4. Luong le A, Fragiadaki M, Smith J, Boyle J, Lutz J, Dean JL, Harten S, Ashcroft M, Walmsley SR, Haskard DO, Maxwell PH, Walczak H, Pusey C, Evans PC. Cezanne regulates inflammatory responses to hypoxia in endothelial cells by targeting TRAF6 for deubiquitination. Circ Res. 2013 Jun 7; 112(12):1583-91.
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    5. Voskarides K, Demosthenous P, Papazachariou L, Arsali M, Athanasiou Y, Zavros M, Stylianou K, Xydakis D, Daphnis E, Gale DP, Maxwell PH, Elia A, Pattaro C, Pierides A, Deltas C. Epistatic role of the MYH9/APOL1 region on familial hematuria genes. PLoS One. 2013; 8(3):e57925.
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    6. Connor TM, Oygar DD, Gale DP, Steenkamp R, Nitsch D, Neild GH, Maxwell PH. Incidence of end-stage renal disease in the Turkish-Cypriot population of Northern Cyprus: a population based study. PLoS One. 2013; 8(1):e54394.
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    7. Gale DP, Maxwell PH. C3 glomerulonephritis and CFHR5 nephropathy. Nephrol Dial Transplant. 2013 Feb; 28(2):282-8.
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    8. Stewart PM, Bryan S, Dukes P, van Oudheusden HL, Walker R, Maxwell PH. What happens to clinical training fellows? A retrospective study of the 20 years outcome of a Medical Research Council UK cohort. BMJ Open. 2012; 2(4).
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    9. Maxwell PH. Increasing evidence that genetic variation in complement factor H related 5 (CFHR5) causes disease: a commentary on 'Atypical haemolytic uremic syndrome and genetic aberrations in the complement factor-H-related 5 gene'. J Hum Genet. 2012 Aug; 57(8):473-4.
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    10. Lange CA, Luhmann UF, Mowat FM, Georgiadis A, West EL, Abrahams S, Sayed H, Powner MB, Fruttiger M, Smith AJ, Sowden JC, Maxwell PH, Ali RR, Bainbridge JW. Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development. Development. 2012 Jul; 139(13):2340-50.
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    11. Mowat FM, Gonzalez F, Luhmann UF, Lange CA, Duran Y, Smith AJ, Maxwell PH, Ali RR, Bainbridge JW. Endogenous erythropoietin protects neuroretinal function in ischemic retinopathy. Am J Pathol. 2012 Apr; 180(4):1726-39.
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    12. Schietke RE, Hackenbeck T, Tran M, Günther R, Klanke B, Warnecke CL, Knaup KX, Shukla D, Rosenberger C, Koesters R, Bachmann S, Betz P, Schley G, Schödel J, Willam C, Winkler T, Amann K, Eckardt KU, Maxwell P, Wiesener MS. Renal tubular HIF-2a expression requires VHL inactivation and causes fibrosis and cysts. PLoS One. 2012; 7(1):e31034.
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    13. Gray RT, O'Donnell ME, Verghis RM, McCluggage WG, Maxwell P, McGuigan JA, Spence GM. Bone marrow micrometastases in esophageal carcinoma: a 10-year follow-up study. Dis Esophagus. 2012 Nov-Dec; 25(8):709-15.
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    14. Maxwell PH. Tumor strengths and frailties: Aspiring to prevent colon cancer. Nat Med. 2012 Jan; 18(1):32-3.
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    15. Yang J, Staples O, Thomas LW, Briston T, Robson M, Poon E, Simões ML, El-Emir E, Buffa FM, Ahmed A, Annear NP, Shukla D, Pedley BR, Maxwell PH, Harris AL, Ashcroft M. Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression. J Clin Invest. 2012 Feb 1; 122(2):600-11.
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    16. Devuyst O, Antignac C, Bindels RJ, Chauveau D, Emma F, Gansevoort R, Maxwell PH, Ong AC, Remuzzi G, Ronco P, Schaefer F. The ERA-EDTA Working Group on inherited kidney disorders. Nephrol Dial Transplant. 2012 Jan; 27(1):67-9.
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    17. Watson CJ, O'Kane H, Maxwell P, Sharaf O, Petak I, Hyland PL, O'Rouke D, McKnight J, Canning P, Williamson K. Identification of a methylation hotspot in the death receptor Fas/CD95 in bladder cancer. Int J Oncol. 2012 Mar; 40(3):645-54.
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    18. Maxwell PH, Burhans WC, Curcio MJ. Retrotransposition is associated with genome instability during chronological aging. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20376-81.
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    19. Adam J, Hatipoglu E, O'Flaherty L, Ternette N, Sahgal N, Lockstone H, Baban D, Nye E, Stamp GW, Wolhuter K, Stevens M, Fischer R, Carmeliet P, Maxwell PH, Pugh CW, Frizzell N, Soga T, Kessler BM, El-Bahrawy M, Ratcliffe PJ, Pollard PJ. Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. Cancer Cell. 2011 Oct 18; 20(4):524-37.
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    20. Takeda Y, Costa S, Delamarre E, Roncal C, Leite de Oliveira R, Squadrito ML, Finisguerra V, Deschoemaeker S, Bruyère F, Wenes M, Hamm A, Serneels J, Magat J, Bhattacharyya T, Anisimov A, Jordan BF, Alitalo K, Maxwell P, Gallez B, Zhuang ZW, Saito Y, Simons M, De Palma M, Mazzone M. Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis. Nature. 2011 Nov 3; 479(7371):122-6.
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    21. Schley G, Klanke B, Schödel J, Forstreuter F, Shukla D, Kurtz A, Amann K, Wiesener MS, Rosen S, Eckardt KU, Maxwell PH, Willam C. Hypoxia-inducible transcription factors stabilization in the thick ascending limb protects against ischemic acute kidney injury. J Am Soc Nephrol. 2011 Nov; 22(11):2004-15.
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    22. Maxwell PH. Seeing the smoking gun: a sensitive and specific method to visualize loss of the tumour suppressor, fumarate hydratase, in human tissues. J Pathol. 2011 Sep; 225(1):1-3.
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    23. Marchbank T, Mahmood A, Harten S, Maxwell PH, Playford RJ. Dimethyloxalyglycine stimulates the early stages of gastrointestinal repair processes through VEGF-dependent mechanisms. Lab Invest. 2011 Dec; 91(12):1684-94.
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    24. Xu J, Wang B, Xu Y, Sun L, Tian W, Shukla D, Barod R, Grillari J, Grillari-Voglauer R, Maxwell PH, Esteban MA. Epigenetic regulation of HIF-1a in renal cancer cells involves HIF-1a/2a binding to a reverse hypoxia-response element. Oncogene. 2012 Feb 23; 31(8):1065-72.
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    25. Harten SK, Esteban MA, Shukla D, Ashcroft M, Maxwell PH. Inactivation of the von Hippel-Lindau tumour suppressor gene induces Neuromedin U expression in renal cancer cells. Mol Cancer. 2011; 10:89.
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    26. Athanasiou Y, Voskarides K, Gale DP, Damianou L, Patsias C, Zavros M, Maxwell PH, Cook HT, Demosthenous P, Hadjisavvas A, Kyriacou K, Zouvani I, Pierides A, Deltas C. Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees. Clin J Am Soc Nephrol. 2011 Jun; 6(6):1436-46.
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    27. Kirbis IS, Maxwell P, Fležar MS, Miller K, Ibrahim M. External quality control for immunocytochemistry on cytology samples: a review of UK NEQAS ICC (cytology module) results. Cytopathology. 2011 Aug; 22(4):230-7.
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    28. Shively SB, Falke EA, Li J, Tran MG, Thompson ER, Maxwell PH, Roessler E, Oldfield EH, Lonser RR, Vortmeyer AO. Developmentally arrested structures preceding cerebellar tumors in von Hippel-Lindau disease. Mod Pathol. 2011 Aug; 24(8):1023-30.
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    29. Shuib S, Wei W, Sur H, Morris MR, McMullan D, Rattenberry E, Meyer E, Maxwell PH, Kishida T, Yao M, Latif F, Maher ER. Copy number profiling in von Hippel-Lindau disease renal cell carcinoma. Genes Chromosomes Cancer. 2011 Jul; 50(7):479-88.
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    30. Bond J, Gale DP, Connor T, Adams S, de Boer J, Gascoyne DM, Williams O, Maxwell PH, Ancliff PJ. Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension. Blood. 2011 Mar 31; 117(13):3699-701.
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    31. Formenti F, Beer PA, Croft QP, Dorrington KL, Gale DP, Lappin TR, Lucas GS, Maher ER, Maxwell PH, McMullin MF, O'Connor DF, Percy MJ, Pugh CW, Ratcliffe PJ, Smith TG, Talbot NP, Robbins PA. Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutation. FASEB J. 2011 Jun; 25(6):2001-11.
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    32. Khan MN, Bhattacharyya T, Andrikopoulos P, Esteban MA, Barod R, Connor T, Ashcroft M, Maxwell PH, Kiriakidis S. Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1a-mediated apoptosis. Br J Cancer. 2011 Mar 29; 104(7):1151-9.
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    33. Walmsley SR, Chilvers ER, Thompson AA, Vaughan K, Marriott HM, Parker LC, Shaw G, Parmar S, Schneider M, Sabroe I, Dockrell DH, Milo M, Taylor CT, Johnson RS, Pugh CW, Ratcliffe PJ, Maxwell PH, Carmeliet P, Whyte MK. Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. J Clin Invest. 2011 Mar; 121(3):1053-63.
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    34. Bou-Gharios G, Amin F, Hill P, Nakamura H, Maxwell P, Fisk NM. Microchimeric fetal cells are recruited to maternal kidney following injury and activate collagen type I transcription. Cells Tissues Organs. 2011; 193(6):379-92.
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    35. Vernon KA, Gale DP, de Jorge EG, McLean AG, Galliford J, Pierides A, Maxwell PH, Taube D, Pickering MC, Cook HT. Recurrence of complement factor H-related protein 5 nephropathy in a renal transplant. Am J Transplant. 2011 Jan; 11(1):152-5.
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    36. Ashrafian H, O'Flaherty L, Adam J, Steeples V, Chung YL, East P, Vanharanta S, Lehtonen H, Nye E, Hatipoglu E, Miranda M, Howarth K, Shukla D, Troy H, Griffiths J, Spencer-Dene B, Yusuf M, Volpi E, Maxwell PH, Stamp G, Poulsom R, Pugh CW, Costa B, Bardella C, Di Renzo MF, Kotlikoff MI, Launonen V, Aaltonen L, El-Bahrawy M, Tomlinson I, Pollard PJ. Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis. Cancer Res. 2010 Nov 15; 70(22):9153-65.
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    37. Evans CE, Humphries J, Mattock K, Waltham M, Wadoodi A, Saha P, Modarai B, Maxwell PH, Maxwell PJ, Smith A. Hypoxia and upregulation of hypoxia-inducible factor 1{alpha} stimulate venous thrombus recanalization. Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12):2443-51.
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    38. Cantley J, Grey ST, Maxwell PH, Withers DJ. The hypoxia response pathway and ß-cell function. Diabetes Obes Metab. 2010 Oct; 12 Suppl 2:159-67.
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    39. Xu J, Li H, Wang B, Xu Y, Yang J, Zhang X, Harten SK, Shukla D, Maxwell PH, Pei D, Esteban MA. VHL inactivation induces HEF1 and Aurora kinase A. J Am Soc Nephrol. 2010 Dec; 21(12):2041-6.
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    40. Hedborg F, Fischer-Colbrie R, Ostlin N, Sandstedt B, Tran MG, Maxwell PH. Differentiation in neuroblastoma: diffusion-limited hypoxia induces neuro-endocrine secretory protein 55 and other markers of a chromaffin phenotype. PLoS One. 2010; 5(9).
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    41. Gale DP, de Jorge EG, Cook HT, Martinez-Barricarte R, Hadjisavvas A, McLean AG, Pusey CD, Pierides A, Kyriacou K, Athanasiou Y, Voskarides K, Deltas C, Palmer A, Frémeaux-Bacchi V, de Cordoba SR, Maxwell PH, Pickering MC. Identification of a mutation in complement factor H-related protein 5 in patients of Cypriot origin with glomerulonephritis. Lancet. 2010 Sep 4; 376(9743):794-801.
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    42. Feehally J, Farrall M, Boland A, Gale DP, Gut I, Heath S, Kumar A, Peden JF, Maxwell PH, Morris DL, Padmanabhan S, Vyse TJ, Zawadzka A, Rees AJ, Lathrop M, Ratcliffe PJ. HLA has strongest association with IgA nephropathy in genome-wide analysis. J Am Soc Nephrol. 2010 Oct; 21(10):1791-7.
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    43. Tambuwala MM, Cummins EP, Lenihan CR, Kiss J, Stauch M, Scholz CC, Fraisl P, Lasitschka F, Mollenhauer M, Saunders SP, Maxwell PH, Carmeliet P, Fallon PG, Schneider M, Taylor CT. Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function. Gastroenterology. 2010 Dec; 139(6):2093-101.
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    44. Mowat FM, Luhmann UF, Smith AJ, Lange C, Duran Y, Harten S, Shukla D, Maxwell PH, Ali RR, Bainbridge JW. HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia. PLoS One. 2010; 5(6):e11103.
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    45. Chambers JC, Zhang W, Lord GM, van der Harst P, Lawlor DA, Sehmi JS, Gale DP, Wass MN, Ahmadi KR, Bakker SJ, Beckmann J, Bilo HJ, Bochud M, Brown MJ, Caulfield MJ, Connell JM, Cook HT, Cotlarciuc I, Davey Smith G, de Silva R, Deng G, Devuyst O, Dikkeschei LD, Dimkovic N, Dockrell M, Dominiczak A, Ebrahim S, Eggermann T, Farrall M, Ferrucci L, Floege J, Forouhi NG, Gansevoort RT, Han X, Hedblad B, Homan van der Heide JJ, Hepkema BG, Hernandez-Fuentes M, Hypponen E, Johnson T, de Jong PE, Kleefstra N, Lagou V, Lapsley M, Li Y, Loos RJ, Luan J, Luttropp K, Maréchal C, Melander O, Munroe PB, Nordfors L, Parsa A, Peltonen L, Penninx BW, Perucha E, Pouta A, Prokopenko I, Roderick PJ, Ruokonen A, Samani NJ, Sanna S, Schalling M, Schlessinger D, Schlieper G, Seelen MA, Shuldiner AR, Sjögren M, Smit JH, Snieder H, Soranzo N, Spector TD, Stenvinkel P, Sternberg MJ, Swaminathan R, Tanaka T, Ubink-Veltmaat LJ, Uda M, Vollenweider P, Wallace C, Waterworth D, Zerres K, Waeber G, Wareham NJ, Maxwell PH, McCarthy MI, Jarvelin MR, Mooser V, Abecasis GR, Lightstone L, Scott J, Navis G, Elliott P, Kooner JS. Genetic loci influencing kidney function and chronic kidney disease. Nat Genet. 2010 May; 42(5):373-5.
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    46. Van de Veire S, Stalmans I, Heindryckx F, Oura H, Tijeras-Raballand A, Schmidt T, Loges S, Albrecht I, Jonckx B, Vinckier S, Van Steenkiste C, Tugues S, Rolny C, De Mol M, Dettori D, Hainaud P, Coenegrachts L, Contreres JO, Van Bergen T, Cuervo H, Xiao WH, Le Henaff C, Buysschaert I, Kharabi Masouleh B, Geerts A, Schomber T, Bonnin P, Lambert V, Haustraete J, Zacchigna S, Rakic JM, Jiménez W, Noël A, Giacca M, Colle I, Foidart JM, Tobelem G, Morales-Ruiz M, Vilar J, Maxwell P, Vinores SA, Carmeliet G, Dewerchin M, Claesson-Welsh L, Dupuy E, Van Vlierberghe H, Christofori G, Mazzone M, Detmar M, Collen D, Carmeliet P. Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease. Cell. 2010 Apr 2; 141(1):178-90.
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    47. Harten SK, Ashcroft M, Maxwell PH. Prolyl hydroxylase domain inhibitors: a route to HIF activation and neuroprotection. Antioxid Redox Signal. 2010 Apr; 12(4):459-80.
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    48. Lou T, Zhang J, Gale DP, Rees AJ, Rhodes B, Feehally J, Li C, Li Y, Li R, Huang W, Hu B, Leung JC, Lam MF, Lai KN, Wang Y, Maxwell PH. Variation in IGHMBP2 is not associated with IgA nephropathy in independent studies of UK Caucasian and Chinese Han patients. Nephrol Dial Transplant. 2010 May; 25(5):1547-54.
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    49. Volke M, Gale DP, Maegdefrau U, Schley G, Klanke B, Bosserhoff AK, Maxwell PH, Eckardt KU, Warnecke C. Evidence for a lack of a direct transcriptional suppression of the iron regulatory peptide hepcidin by hypoxia-inducible factors. PLoS One. 2009; 4(11):e7875.
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    50. Gale DP, Maxwell PH. The role of HIF in immunity. Int J Biochem Cell Biol. 2010 Apr; 42(4):486-94.
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    51. Ashby DR, Gale DP, Busbridge M, Murphy KG, Duncan ND, Cairns TD, Taube DH, Bloom SR, Tam FW, Chapman R, Maxwell PH, Choi P. Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin. Haematologica. 2010 Mar; 95(3):505-8.
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    52. Chambers JC, Zhang W, Li Y, Sehmi J, Wass MN, Zabaneh D, Hoggart C, Bayele H, McCarthy MI, Peltonen L, Freimer NB, Srai SK, Maxwell PH, Sternberg MJ, Ruokonen A, Abecasis G, Jarvelin MR, Scott J, Elliott P, Kooner JS. Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nat Genet. 2009 Nov; 41(11):1170-2.
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    53. Schneider M, Van Geyte K, Fraisl P, Kiss J, Aragonés J, Mazzone M, Mairbäurl H, De Bock K, Jeoung NH, Mollenhauer M, Georgiadou M, Bishop T, Roncal C, Sutherland A, Jordan B, Gallez B, Weitz J, Harris RA, Maxwell P, Baes M, Ratcliffe P, Carmeliet P. Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury. Gastroenterology. 2010 Mar; 138(3):1143-54.e1-2.
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    54. Wiesener MS, Maxwell PH, Eckardt KU. Novel insights into the role of the tumor suppressor von Hippel Lindau in cellular differentiation, ciliary biology, and cyst repression. J Mol Med (Berl). 2009 Sep; 87(9):871-7.
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    55. Zawislak A, Donnelly RF, McCluggage WG, Price JH, McClelland HR, Woolfson AD, Dobbs S, Maxwell P, McCarron PA. Clinical and immunohistochemical assessment of vulval intraepithelial neoplasia following photodynamic therapy using a novel bioadhesive patch-type system loaded with 5-aminolevulinic acid. Photodiagnosis Photodyn Ther. 2009 Mar; 6(1):28-40.
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    56. Stamenova R, Maxwell PH, Kenny AE, Curcio MJ. Rrm3 protects the Saccharomyces cerevisiae genome from instability at nascent sites of retrotransposition. Genetics. 2009 Jul; 182(3):711-23.
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    57. Maxwell PH. Oxygen availability sHIFts the cell cycle. Cell Cycle. 2009 May 1; 8(9):1307.
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    58. Hedén P, Adams WP, Maxwell P, Nava M, Scheflan M, Stan C. Aesthetic breast surgery: consulting for the future--proposals for improving doctor-patient interactions. Aesthetic Plast Surg. 2009 May; 33(3):388-94; discussion 395.
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    59. Ebbesen P, Pettersen EO, Gorr TA, Jobst G, Williams K, Kieninger J, Wenger RH, Pastorekova S, Dubois L, Lambin P, Wouters BG, Van Den Beucken T, Supuran CT, Poellinger L, Ratcliffe P, Kanopka A, Görlach A, Gasmann M, Harris AL, Maxwell P, Scozzafava A. Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies. J Enzyme Inhib Med Chem. 2009 Apr; 24 Suppl 1:1-39.
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    60. Tuthill M, Barod R, Pyle L, Cook T, Chew S, Gore M, Maxwell P, Eisen T. A report of succinate dehydrogenase B deficiency associated with metastatic papillary renal cell carcinoma: successful treatment with the multi-targeted tyrosine kinase inhibitor sunitinib. BMJ Case Rep. 2009; 2009.
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    61. Mazzone M, Dettori D, Leite de Oliveira R, Loges S, Schmidt T, Jonckx B, Tian YM, Lanahan AA, Pollard P, Ruiz de Almodovar C, De Smet F, Vinckier S, Aragonés J, Debackere K, Luttun A, Wyns S, Jordan B, Pisacane A, Gallez B, Lampugnani MG, Dejana E, Simons M, Ratcliffe P, Maxwell P, Carmeliet P. Heterozygous deficiency of PHD2 restores tumor oxygenation and inhibits metastasis via endothelial normalization. Cell. 2009 Mar 6; 136(5):839-51.
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    62. Ashby DR, Gale DP, Busbridge M, Murphy KG, Duncan ND, Cairns TD, Taube DH, Bloom SR, Tam FW, Chapman RS, Maxwell PH, Choi P. Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease. Kidney Int. 2009 May; 75(9):976-81.
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    63. Ma D, Lim T, Xu J, Tang H, Wan Y, Zhao H, Hossain M, Maxwell PH, Maze M. Xenon preconditioning protects against renal ischemic-reperfusion injury via HIF-1alpha activation. J Am Soc Nephrol. 2009 Apr; 20(4):713-20.
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    64. Harten SK, Esteban MA, Maxwell PH. Identification of novel VHL regulated genes by transcriptomic analysis of RCC10 renal carcinoma cells. Adv Enzyme Regul. 2009; 49(1):43-52.
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    65. Harten SK, Shukla D, Barod R, Hergovich A, Balda MS, Matter K, Esteban MA, Maxwell PH. Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin. Mol Biol Cell. 2009 Feb; 20(3):1089-101.
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    66. Cantley J, Selman C, Shukla D, Abramov AY, Forstreuter F, Esteban MA, Claret M, Lingard SJ, Clements M, Harten SK, Asare-Anane H, Batterham RL, Herrera PL, Persaud SJ, Duchen MR, Maxwell PH, Withers DJ. Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice. J Clin Invest. 2009 Jan; 119(1):125-35.
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    67. Wilson C, Scullin P, Worthington J, Seaton A, Maxwell P, O'Rourke D, Johnston PG, McKeown SR, Wilson RH, O'Sullivan JM, Waugh DJ. Dexamethasone potentiates the antiangiogenic activity of docetaxel in castration-resistant prostate cancer. Br J Cancer. 2008 Dec 16; 99(12):2054-64.
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    68. Brooks JT, Elvidge GP, Glenny L, Gleadle JM, Liu C, Ragoussis J, Smith TG, Talbot NP, Winchester L, Maxwell PH, Robbins PA. Variations within oxygen-regulated gene expression in humans. J Appl Physiol (1985). 2009 Jan; 106(1):212-20.
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    69. Mehta GU, Shively SB, Duong H, Tran MG, Moncrief TJ, Smith JH, Li J, Edwards NA, Lonser RR, Zhuang Z, Merrill MJ, Raffeld M, Maxwell PH, Oldfield EH, Vortmeyer AO. Progression of epididymal maldevelopment into hamartoma-like neoplasia in VHL disease. Neoplasia. 2008 Oct; 10(10):1146-53.
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    70. Lutz J, Luong le A, Strobl M, Deng M, Huang H, Anton M, Zakkar M, Enesa K, Chaudhury H, Haskard DO, Baumann M, Boyle J, Harten S, Maxwell PH, Pusey C, Heemann U, Evans PC. The A20 gene protects kidneys from ischaemia/reperfusion injury by suppressing pro-inflammatory activation. J Mol Med (Berl). 2008 Dec; 86(12):1329-39.
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    71. Gale DP, Harten SK, Reid CD, Tuddenham EG, Maxwell PH. Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 alpha mutation. Blood. 2008 Aug 1; 112(3):919-21.
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    72. Maxwell PH, Curcio MJ. Incorporation of Y'-Ty1 cDNA destabilizes telomeres in Saccharomyces cerevisiae telomerase-negative mutants. Genetics. 2008 Aug; 179(4):2313-7.
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    73. Bishop T, Gallagher D, Pascual A, Lygate CA, de Bono JP, Nicholls LG, Ortega-Saenz P, Oster H, Wijeyekoon B, Sutherland AI, Grosfeld A, Aragones J, Schneider M, van Geyte K, Teixeira D, Diez-Juan A, Lopez-Barneo J, Channon KM, Maxwell PH, Pugh CW, Davies AM, Carmeliet P, Ratcliffe PJ. Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice. Mol Cell Biol. 2008 May; 28(10):3386-400.
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    74. Ashby D, Smith C, Hurril R, Maxwell P, Brown E. Dialysis survivors: clinical status of patients on treatment for more than 10 years. Nephron Clin Pract. 2008; 108(3):c207-12.
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    75. Thalheimer U, Wright JL, Maxwell P, Firth J, Millar A. Sebaceous glands in the esophagus. Endoscopy. 2008 Sep; 40 Suppl 2:E57.
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    76. Mikhaylova O, Ignacak ML, Barankiewicz TJ, Harbaugh SV, Yi Y, Maxwell PH, Schneider M, Van Geyte K, Carmeliet P, Revelo MP, Wyder M, Greis KD, Meller J, Czyzyk-Krzeska MF. The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress. Mol Cell Biol. 2008 Apr; 28(8):2701-17.
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    77. Maxwell PH, Belote JM, Levis RW. Developmental and tissue-specific accumulation pattern for the Drosophila melanogaster TART ORF1 protein. Gene. 2008 May 31; 415(1-2):32-9.
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    78. Angelillo-Scherrer A, Burnier L, Lambrechts D, Fish RJ, Tjwa M, Plaisance S, Sugamele R, DeMol M, Martinez-Soria E, Maxwell PH, Lemke G, Goff SP, Matsushima GK, Earp HS, Chanson M, Collen D, Izui S, Schapira M, Conway EM, Carmeliet P. Role of Gas6 in erythropoiesis and anemia in mice. J Clin Invest. 2008 Feb; 118(2):583-96.
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    79. Aragonés J, Schneider M, Van Geyte K, Fraisl P, Dresselaers T, Mazzone M, Dirkx R, Zacchigna S, Lemieux H, Jeoung NH, Lambrechts D, Bishop T, Lafuste P, Diez-Juan A, Harten SK, Van Noten P, De Bock K, Willam C, Tjwa M, Grosfeld A, Navet R, Moons L, Vandendriessche T, Deroose C, Wijeyekoon B, Nuyts J, Jordan B, Silasi-Mansat R, Lupu F, Dewerchin M, Pugh C, Salmon P, Mortelmans L, Gallez B, Gorus F, Buyse J, Sluse F, Harris RA, Gnaiger E, Hespel P, Van Hecke P, Schuit F, Van Veldhoven P, Ratcliffe P, Baes M, Maxwell P, Carmeliet P. Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet. 2008 Feb; 40(2):170-80.
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    80. Smith TG, Brooks JT, Balanos GM, Lappin TR, Layton DM, Leedham DL, Liu C, Maxwell PH, McMullin MF, McNamara CJ, Percy MJ, Pugh CW, Ratcliffe PJ, Talbot NP, Treacy M, Robbins PA. Mutation of the von Hippel-Lindau gene alters human cardiopulmonary physiology. Adv Exp Med Biol. 2008; 605:51-6.
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    81. Hill P, Shukla D, Tran MG, Aragones J, Cook HT, Carmeliet P, Maxwell PH. Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury. J Am Soc Nephrol. 2008 Jan; 19(1):39-46.
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    82. Elliott K, Hamilton PW, Maxwell P. Fluorescence (FISH) and chromogenic (CISH) in situ hybridisation in prostate carcinoma cell lines: comparison and use of virtual microscopy. Br J Biomed Sci. 2008; 65(4):167-71.
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    83. Maxwell PH, Curcio MJ. Retrosequence formation restructures the yeast genome. Genes Dev. 2007 Dec 15; 21(24):3308-18.
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    84. Wiesener MS, Münchenhagen P, Gläser M, Sobottka BA, Knaup KX, Jozefowski K, Jürgensen JS, Roigas J, Warnecke C, Gröne HJ, Maxwell PH, Willam C, Eckardt KU. Erythropoietin gene expression in renal carcinoma is considerably more frequent than paraneoplastic polycythemia. Int J Cancer. 2007 Dec 1; 121(11):2434-42.
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    85. Pepper RJ, Gale DP, Wajed J, Bommayya G, Ashby D, McLean A, Laffan M, Maxwell PH. Inadvertent postdialysis anticoagulation due to heparin line locks. Hemodial Int. 2007 Oct; 11(4):430-4.
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    86. Hoogewijs D, Terwilliger NB, Webster KA, Powell-Coffman JA, Tokishita S, Yamagata H, Hankeln T, Burmester T, Rytkönen KT, Nikinmaa M, Abele D, Heise K, Lucassen M, Fandrey J, Maxwell PH, Påhlman S, Gorr TA. From critters to cancers: bridging comparative and clinical research on oxygen sensing, HIF signaling, and adaptations towards hypoxia. Integr Comp Biol. 2007 Oct; 47(4):552-77.
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    87. Rajatapiti P, van der Horst IW, de Rooij JD, Tran MG, Maxwell PH, Tibboel D, Rottier R, de Krijger RR. Expression of hypoxia-inducible factors in normal human lung development. Pediatr Dev Pathol. 2008 May-Jun; 11(3):193-9.
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    88. Black C, Maxwell P, Marshall M, Rees M, Dolphin T. MTAS: which way now? Interview by Rebecca Coombes. BMJ. 2007 Jun 23; 334(7607):1300.
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    89. Maxwell PH, Curcio MJ. Host factors that control long terminal repeat retrotransposons in Saccharomyces cerevisiae: implications for regulation of mammalian retroviruses. Eukaryot Cell. 2007 Jul; 6(7):1069-80.
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    90. Pollard PJ, Spencer-Dene B, Shukla D, Howarth K, Nye E, El-Bahrawy M, Deheragoda M, Joannou M, McDonald S, Martin A, Igarashi P, Varsani-Brown S, Rosewell I, Poulsom R, Maxwell P, Stamp GW, Tomlinson IP. Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway. Cancer Cell. 2007 Apr; 11(4):311-9.
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    91. Boutet A, Esteban MA, Maxwell PH, Nieto MA. Reactivation of Snail genes in renal fibrosis and carcinomas: a process of reversed embryogenesis? Cell Cycle. 2007 Mar 15; 6(6):638-42.
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    92. Kiriakidis S, Esteban MA, Maxwell PH. Genetic insights into the hypoxia-inducible factor (HIF) pathway. Adv Enzyme Regul. 2007; 47:288-306.
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    93. Zwerts F, Lupu F, De Vriese A, Pollefeyt S, Moons L, Altura RA, Jiang Y, Maxwell PH, Hill P, Oh H, Rieker C, Collen D, Conway SJ, Conway EM. Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure. Blood. 2007 Jun 1; 109(11):4742-52.
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    94. McKnight J, Maxwell P, O'Rourke D, Anderson N, Watson C, Patterson A, Healy E, Williamson K. The relationship between cytokeratin expression in bladder washings and resected tumour specimens. Histopathology. 2007 Jan; 50(2):275-8.
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    95. Boutet A, De Frutos CA, Maxwell PH, Mayol MJ, Romero J, Nieto MA. Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney. EMBO J. 2006 Nov 29; 25(23):5603-13.
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    96. Vortmeyer AO, Tran MG, Zeng W, Gläsker S, Riley C, Tsokos M, Ikejiri B, Merrill MJ, Raffeld M, Zhuang Z, Lonser RR, Maxwell PH, Oldfield EH. Evolution of VHL tumourigenesis in nerve root tissue. J Pathol. 2006 Nov; 210(3):374-82.
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    97. Maxwell PH, Belote JM, Levis RW. Identification of multiple transcription initiation, polyadenylation, and splice sites in the Drosophila melanogaster TART family of telomeric retrotransposons. Nucleic Acids Res. 2006; 34(19):5498-507.
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    98. Gläsker S, Tran MG, Shively SB, Ikejiri B, Lonser RR, Maxwell PH, Zhuang Z, Oldfield EH, Vortmeyer AO. Epididymal cystadenomas and epithelial tumourlets: effects of VHL deficiency on the human epididymis. J Pathol. 2006 Sep; 210(1):32-41.
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    99. Smith TG, Brooks JT, Balanos GM, Lappin TR, Layton DM, Leedham DL, Liu C, Maxwell PH, McMullin MF, McNamara CJ, Percy MJ, Pugh CW, Ratcliffe PJ, Talbot NP, Treacy M, Robbins PA. Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology. PLoS Med. 2006 Jul; 3(7):e290.
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    100. Koumenis C, Maxwell PH. Low oxygen stimulates the intellect. Symposium on hypoxia and development, physiology and disease. EMBO Rep. 2006 Jul; 7(7):679-84.
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    101. Willam C, Maxwell PH, Nichols L, Lygate C, Tian YM, Bernhardt W, Wiesener M, Ratcliffe PJ, Eckardt KU, Pugh CW. HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation. J Mol Cell Cardiol. 2006 Jul; 41(1):68-77.
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    102. Walmsley SR, Cowburn AS, Clatworthy MR, Morrell NW, Roper EC, Singleton V, Maxwell P, Whyte MK, Chilvers ER. Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis. Blood. 2006 Nov 1; 108(9):3176-8.
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    103. Esteban MA, Harten SK, Tran MG, Maxwell PH. Formation of primary cilia in the renal epithelium is regulated by the von Hippel-Lindau tumor suppressor protein. J Am Soc Nephrol. 2006 Jul; 17(7):1801-6.
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    104. Wang S, Voisin MB, Larbi KY, Dangerfield J, Scheiermann C, Tran M, Maxwell PH, Sorokin L, Nourshargh S. Venular basement membranes contain specific matrix protein low expression regions that act as exit points for emigrating neutrophils. J Exp Med. 2006 Jun 12; 203(6):1519-32.
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    105. Esteban MA, Tran MG, Harten SK, Hill P, Castellanos MC, Chandra A, Raval R, O'brien TS, Maxwell PH. Regulation of E-cadherin expression by VHL and hypoxia-inducible factor. Cancer Res. 2006 Apr 1; 66(7):3567-75.
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    106. Du Roure C, Takács K, Maxwell PH, Roberts I, Dazzi F, Cannella L, Merkenschlager M, Fisher AG. Correction of severe anaemia using immuno-regulated gene therapy is achieved by restoring the early erythroblast compartment. Br J Haematol. 2006 Mar; 132(5):608-14.
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    107. Xia Y, Li Y, Du Y, Yang N, Li C, Leung JC, Lam MF, Huang W, Chen S, Maxwell PH, Lai KN, Wang Y. Association of MEGSIN 2093C-2180T haplotype at the 3' untranslated region with disease severity and progression of IgA nephropathy. Nephrol Dial Transplant. 2006 Jun; 21(6):1570-4.
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    108. Paul I, Lappin TR, Maxwell P, Graham AN. Pre-operative plasma erythropoietin concentration and survival following surgery for non-small cell lung cancer. Lung Cancer. 2006 Mar; 51(3):329-34.
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    109. Percy MJ, Zhao Q, Flores A, Harrison C, Lappin TR, Maxwell PH, McMullin MF, Lee FS. A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis. Proc Natl Acad Sci U S A. 2006 Jan 17; 103(3):654-9.
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    110. Kinderlerer AR, Steinberg R, Johns M, Harten SK, Lidington EA, Haskard DO, Maxwell PH, Mason JC. Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis. Arthritis Res Ther. 2006; 8(4):R130.
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    111. van der Schaft DW, Hillen F, Pauwels P, Kirschmann DA, Castermans K, Egbrink MG, Tran MG, Sciot R, Hauben E, Hogendoorn PC, Delattre O, Maxwell PH, Hendrix MJ, Griffioen AW. Tumor cell plasticity in Ewing sarcoma, an alternative circulatory system stimulated by hypoxia. Cancer Res. 2005 Dec 15; 65(24):11520-8.
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    112. Gläsker S, Lonser RR, Tran MG, Ikejiri B, Butman JA, Zeng W, Maxwell PH, Zhuang Z, Oldfield EH, Vortmeyer AO. Effects of VHL deficiency on endolymphatic duct and sac. Cancer Res. 2005 Dec 1; 65(23):10847-53.
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    113. Maxwell PH, Wang Y. Genetic studies of IgA nephropathy. Nephron Exp Nephrol. 2006; 102(3-4):e76-80.
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    114. Alexakis C, Maxwell P, Bou-Gharios G. Organ-specific collagen expression: implications for renal disease. Nephron Exp Nephrol. 2006; 102(3-4):e71-5.
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    115. Esteban MA, Maxwell PH. HIF, a missing link between metabolism and cancer. Nat Med. 2005 Oct; 11(10):1047-8.
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    116. Maxwell PH. Hypoxia-inducible factor as a physiological regulator. Exp Physiol. 2005 Nov; 90(6):791-7.
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    117. Maxwell PH. A common pathway for genetic events leading to pheochromocytoma. Cancer Cell. 2005 Aug; 8(2):91-3.
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    118. Acker T, Diez-Juan A, Aragones J, Tjwa M, Brusselmans K, Moons L, Fukumura D, Moreno-Murciano MP, Herbert JM, Burger A, Riedel J, Elvert G, Flamme I, Maxwell PH, Collen D, Dewerchin M, Jain RK, Plate KH, Carmeliet P. Genetic evidence for a tumor suppressor role of HIF-2alpha. Cancer Cell. 2005 Aug; 8(2):131-41.
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    119. Raval RR, Lau KW, Tran MG, Sowter HM, Mandriota SJ, Li JL, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ. Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol Cell Biol. 2005 Jul; 25(13):5675-86.
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    120. Esteban MA, Maxwell PH. Manipulation of oxygen tensions for in vitro cell culture using a hypoxic workstation. Expert Rev Proteomics. 2005 Jun; 2(3):307-14.
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    121. Summers SA, Laing C, Cook TH, Maxwell PH. Is it rejection? Be on the lookout for 'decoys'. Nephrol Dial Transplant. 2005 Sep; 20(9):2002-4.
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    122. Maxwell PH. The HIF pathway in cancer. Semin Cell Dev Biol. 2005 Aug-Oct; 16(4-5):523-30.
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    123. Chen S, Song C, Guo H, Xu P, Huang W, Zhou Y, Sun J, Li CX, Du Y, Li X, Liu Z, Geng D, Maxwell PH, Zhang C, Wang Y. Distinct novel mutations affecting the same base in the NIPA1 gene cause autosomal dominant hereditary spastic paraplegia in two Chinese families. Hum Mutat. 2005 Feb; 25(2):135-41.
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    124. Heatley MK, Maxwell P, Whiteside C, Ewing P, Toner PG. The prognostic relevance of estimates of proliferative activity in early breast cancer. Histopathology. 2005 Jan; 46(1):110-1.
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    125. Morrison ML, Williamson K, Arthur K, Price GJ, Hamilton PW, Maxwell P. Phenotypic changes in mitochondrial membrane potential (Delta psi(m)) during valinomycin-induced depolarisation and apoptosis. Cell Oncol. 2005; 27(4):231-6.
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    126. Maxwell PH, Coombes C, Kenny AE, Lawler JF, Boeke JD, Curcio MJ. Ty1 mobilizes subtelomeric Y' elements in telomerase-negative Saccharomyces cerevisiae survivors. Mol Cell Biol. 2004 Nov; 24(22):9887-98.
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    127. Jürgensen JS, Rosenberger C, Wiesener MS, Warnecke C, Hörstrup JH, Gräfe M, Philipp S, Griethe W, Maxwell PH, Frei U, Bachmann S, Willenbrock R, Eckardt KU. Persistent induction of HIF-1alpha and -2alpha in cardiomyocytes and stromal cells of ischemic myocardium. FASEB J. 2004 Sep; 18(12):1415-7.
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    128. Li YJ, Du Y, Li CX, Guo H, Leung JC, Lam MF, Yang N, Huang F, Chen Y, Fang JQ, Maxwell PH, Lai KN, Wang Y. Family-based association study showing that immunoglobulin A nephropathy is associated with the polymorphisms 2093C and 2180T in the 3' untranslated region of the Megsin gene. J Am Soc Nephrol. 2004 Jul; 15(7):1739-43.
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    129. Kaufman B, Scharf O, Arbeit J, Ashcroft M, Brown JM, Bruick RK, Chapman JD, Evans SM, Giaccia AJ, Harris AL, Huang E, Johnson R, Kaelin W, Koch CJ, Maxwell P, Mitchell J, Neckers L, Powis G, Rajendran J, Semenza GL, Simons J, Storkebaum E, Welch MJ, Whitelaw M, Melillo G, Ivy SP. Proceedings of the Oxygen Homeostasis/Hypoxia Meeting. Cancer Res. 2004 May 1; 64(9):3350-6.
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    130. Wykoff CC, Sotiriou C, Cockman ME, Ratcliffe PJ, Maxwell P, Liu E, Harris AL. Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene. Br J Cancer. 2004 Mar 22; 90(6):1235-43.
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    131. Maxwell PH. HIF-1's relationship to oxygen: simple yet sophisticated. Cell Cycle. 2004 Feb; 3(2):156-9.
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    132. Maxwell P, Salnikow K. HIF-1: an oxygen and metal responsive transcription factor. Cancer Biol Ther. 2004 Jan; 3(1):29-35.
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    133. Willam C, Nicholls LG, Ratcliffe PJ, Pugh CW, Maxwell PH. The prolyl hydroxylase enzymes that act as oxygen sensors regulating destruction of hypoxia-inducible factor alpha. Adv Enzyme Regul. 2004; 44:75-92.
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    134. Maxwell P. HIF-1: an oxygen response system with special relevance to the kidney. J Am Soc Nephrol. 2003 Nov; 14(11):2712-22.
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    135. Brusselmans K, Compernolle V, Tjwa M, Wiesener MS, Maxwell PH, Collen D, Carmeliet P. Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia. J Clin Invest. 2003 May; 111(10):1519-27.
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    136. Hedborg F, Ullerås E, Grimelius L, Wassberg E, Maxwell PH, Hero B, Berthold F, Schilling F, Harms D, Sandstedt B, Franklin G. Evidence for hypoxia-induced neuronal-to-chromaffin metaplasia in neuroblastoma. FASEB J. 2003 Apr; 17(6):598-609.
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    137. Shah VI, Freites ON, Maxwell P, McCluggage WG. Inhibin is more specific than calretinin as an immunohistochemical marker for differentiating sarcomatoid granulosa cell tumour of the ovary from other spindle cell neoplasms. J Clin Pathol. 2003 Mar; 56(3):221-4.
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    138. Wiesener MS, Maxwell PH. HIF and oxygen sensing; as important to life as the air we breathe? Ann Med. 2003; 35(3):183-90.
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    139. Wiesener MS, Jürgensen JS, Rosenberger C, Scholze CK, Hörstrup JH, Warnecke C, Mandriota S, Bechmann I, Frei UA, Pugh CW, Ratcliffe PJ, Bachmann S, Maxwell PH, Eckardt KU. Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs. FASEB J. 2003 Feb; 17(2):271-3.
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    140. Ang SO, Chen H, Hirota K, Gordeuk VR, Jelinek J, Guan Y, Liu E, Sergueeva AI, Miasnikova GY, Mole D, Maxwell PH, Stockton DW, Semenza GL, Prchal JT. Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia. Nat Genet. 2002 Dec; 32(4):614-21.
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    141. Binley K, Askham Z, Iqball S, Spearman H, Martin L, de Alwis M, Thrasher AJ, Ali RR, Maxwell PH, Kingsman S, Naylor S. Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy. Blood. 2002 Oct 1; 100(7):2406-13.
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    142. Cameron RI, Maxwell P, Jenkins D, McCluggage WG. Immunohistochemical staining with MIB1, bcl2 and p16 assists in the distinction of cervical glandular intraepithelial neoplasia from tubo-endometrial metaplasia, endometriosis and microglandular hyperplasia. Histopathology. 2002 Oct; 41(4):313-21.
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    143. Rinsch C, Dupraz P, Schneider BL, Déglon N, Maxwell PH, Ratcliffe PJ, Aebischer P. Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia. Kidney Int. 2002 Oct; 62(4):1395-401.
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    144. Willam C, Masson N, Tian YM, Mahmood SA, Wilson MI, Bicknell R, Eckardt KU, Maxwell PH, Ratcliffe PJ, Pugh CW. Peptide blockade of HIFalpha degradation modulates cellular metabolism and angiogenesis. Proc Natl Acad Sci U S A. 2002 Aug 6; 99(16):10423-8.
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    145. Rosenberger C, Mandriota S, Jürgensen JS, Wiesener MS, Hörstrup JH, Frei U, Ratcliffe PJ, Maxwell PH, Bachmann S, Eckardt KU. Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys. J Am Soc Nephrol. 2002 Jul; 13(7):1721-32.
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    146. Maxwell PH. Oxygen homeostasis and cancer: insights from a rare disease. Clin Med. 2002 Jul-Aug; 2(4):356-62.
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    147. McNeill LA, Hewitson KS, Gleadle JM, Horsfall LE, Oldham NJ, Maxwell PH, Pugh CW, Ratcliffe PJ, Schofield CJ. The use of dioxygen by HIF prolyl hydroxylase (PHD1). Bioorg Med Chem Lett. 2002 Jun 17; 12(12):1547-50.
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    148. Hon WC, Wilson MI, Harlos K, Claridge TD, Schofield CJ, Pugh CW, Maxwell PH, Ratcliffe PJ, Stuart DI, Jones EY. Structural basis for the recognition of hydroxyproline in HIF-1 alpha by pVHL. Nature. 2002 Jun 27; 417(6892):975-8.
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    149. Mandriota SJ, Turner KJ, Davies DR, Murray PG, Morgan NV, Sowter HM, Wykoff CC, Maher ER, Harris AL, Ratcliffe PJ, Maxwell PH. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell. 2002 Jun; 1(5):459-68.
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    150. Heatley MK, Ewings P, Odling Smee W, Maxwell P, Toner PG. Vimentin expression does not assist in predicting survival in ductal carcinoma of the breast. Pathology. 2002 Jun; 34(3):230-2.
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    151. Turner KJ, Moore JW, Jones A, Taylor CF, Cuthbert-Heavens D, Han C, Leek RD, Gatter KC, Maxwell PH, Ratcliffe PJ, Cranston D, Harris AL. Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation. Cancer Res. 2002 May 15; 62(10):2957-61.
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    152. Graham AN, Maxwell P, Mulholland K, Patterson AH, Anderson N, McManus KG, Bharucha H, McGuigan JA. Increased nm23 immunoreactivity is associated with selective inhibition of systemic tumour cell dissemination. J Clin Pathol. 2002 Mar; 55(3):184-9.
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    153. Cruz I, Napier SS, van der Waal I, Snijders PJ, Walboomers JM, Lamey PJ, Cowan CG, Gregg TA, Maxwell P, Meijer CJ. Suprabasal p53 immunoexpression is strongly associated with high grade dysplasia and risk for malignant transformation in potentially malignant oral lesions from Northern Ireland. J Clin Pathol. 2002 Feb; 55(2):98-104.
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    154. Onita T, Ji PG, Xuan JW, Sakai H, Kanetake H, Maxwell PH, Fong GH, Gabril MY, Moussa M, Chin JL. Hypoxia-induced, perinecrotic expression of endothelial Per-ARNT-Sim domain protein-1/hypoxia-inducible factor-2alpha correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer. Clin Cancer Res. 2002 Feb; 8(2):471-80.
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    155. Maxwell PH, Ratcliffe PJ. Oxygen sensors and angiogenesis. Semin Cell Dev Biol. 2002 Feb; 13(1):29-37.
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    156. Mole DR, Pugh CW, Ratcliffe PJ, Maxwell PH. Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex. Adv Enzyme Regul. 2002; 42:333-47.
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    157. Bielanski A, Simar C, Maxwell P, Nadin-Davis S. Bovine immunodeficiency virus in relation to embryos fertilized in vitro. Vet Res Commun. 2001 Dec; 25(8):663-73.
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    158. Washburn K, Speeg KV, Esterl R, Cigarroa F, Pollack M, Tourtellot C, Maxwell P, Halff G. Steroid elimination 24 hours after liver transplantation using daclizumab, tacrolimus, and mycophenolate mofetil. Transplantation. 2001 Nov 27; 72(10):1675-9.
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    159. Longley DB, Ferguson PR, Boyer J, Latif T, Lynch M, Maxwell P, Harkin DP, Johnston PG. Characterization of a thymidylate synthase (TS)-inducible cell line: a model system for studying sensitivity to TS- and non-TS-targeted chemotherapies. Clin Cancer Res. 2001 Nov; 7(11):3533-9.
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    160. Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ. C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell. 2001 Oct 5; 107(1):43-54.
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    161. Masson N, Willam C, Maxwell PH, Pugh CW, Ratcliffe PJ. Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation. EMBO J. 2001 Sep 17; 20(18):5197-206.
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    162. Vaux EC, Wood SM, Cockman ME, Nicholls LG, Yeates KM, Pugh CW, Maxwell PH, Ratcliffe PJ. Selection of mutant CHO cells with constitutive activation of the HIF system and inactivation of the von Hippel-Lindau tumor suppressor. J Biol Chem. 2001 Nov 23; 276(47):44323-30.
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    163. McCluggage WG, Sumathi VP, Maxwell P. CD10 is a sensitive and diagnostically useful immunohistochemical marker of normal endometrial stroma and of endometrial stromal neoplasms. Histopathology. 2001 Sep; 39(3):273-8.
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    164. Duggan BJ, Maxwell P, Kelly JD, Canning P, Anderson NH, Keane PF, Johnston SR, Williamson KE. The effect of antisense Bcl-2 oligonucleotides on Bcl-2 protein expression and apoptosis in human bladder transitional cell carcinoma. J Urol. 2001 Sep; 166(3):1098-105.
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    165. Brusselmans K, Bono F, Maxwell P, Dor Y, Dewerchin M, Collen D, Herbert JM, Carmeliet P. Hypoxia-inducible factor-2alpha (HIF-2alpha) is involved in the apoptotic response to hypoglycemia but not to hypoxia. J Biol Chem. 2001 Oct 19; 276(42):39192-6.
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    166. Clifford SC, Astuti D, Hooper L, Maxwell PH, Ratcliffe PJ, Maher ER. The pVHL-associated SCF ubiquitin ligase complex: molecular genetic analysis of elongin B and C, Rbx1 and HIF-1alpha in renal cell carcinoma. Oncogene. 2001 Aug 16; 20(36):5067-74.
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    167. Elkablawy MA, Maxwell P, Williamson K, Anderson N, Hamilton PW. Apoptosis and cell-cycle regulatory proteins in colorectal carcinoma: relationship to tumour stage and patient survival. J Pathol. 2001 Aug; 194(4):436-43.
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    168. Pugh CW, Gleadle J, Maxwell PH. Hypoxia and oxidative stress in breast cancer. Hypoxia signalling pathways. Breast Cancer Res. 2001; 3(5):313-7.
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    169. Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU. Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas. Cancer Res. 2001 Jul 1; 61(13):5215-22.
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    170. Mole DR, Maxwell PH, Pugh CW, Ratcliffe PJ. Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing. IUBMB Life. 2001 Jul; 52(1-2):43-7.
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    171. Maxwell PH, Pugh CW, Ratcliffe PJ. Activation of the HIF pathway in cancer. Curr Opin Genet Dev. 2001 Jun; 11(3):293-9.
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    172. McCluggage WG, Maxwell P, Veenstra H, Fick CE, Laeng RH, Tiltman AJ. Monoclonal antibody SM047 as an immunohistochemical marker of ovarian adenocarcinoma. Histopathology. 2001 Jun; 38(6):542-9.
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    173. Clifford SC, Cockman ME, Smallwood AC, Mole DR, Woodward ER, Maxwell PH, Ratcliffe PJ, Maher ER. Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease. Hum Mol Genet. 2001 May 1; 10(10):1029-38.
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    174. McCluggage WG, Maxwell P. Immunohistochemical staining for calretinin is useful in the diagnosis of ovarian sex cord-stromal tumours. Histopathology. 2001 May; 38(5):403-8.
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    175. Maxwell PH, Buckley C, Gleadle JM, Mason PD. Nasty shock after an anti-emetic. Nephrol Dial Transplant. 2001 May; 16(5):1069-72.
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    176. Jaakkola P, Mole DR, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, von Kriegsheim A, Hebestreit HF, Mukherji M, Schofield CJ, Maxwell PH, Pugh CW, Ratcliffe PJ. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science. 2001 Apr 20; 292(5516):468-72.
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    177. Venkatraman L, Maxwell P, McCluggage WG. Thyroglobulin immunoreactivity in lymph node histiocytes: a potential diagnostic pitfall. J Clin Pathol. 2001 Apr; 54(4):314-6.
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    178. McKeveney PJ, Hodges VM, Mullan RN, Maxwell P, Simpson D, Thompson A, Winter PC, Lappin TR, Maxwell AP. Characterization and localization of expression of an erythropoietin-induced gene, ERIC-1/TACC3, identified in erythroid precursor cells. Br J Haematol. 2001 Mar; 112(4):1016-24.
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    179. Yap LB, Bowler IC, Maxwell PH. Guiding hands of our teachers. Lancet. 2001 Feb 10; 357(9254):480.
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    180. Bielanski A, Nadin-Davis S, Simard C, Maxwell P, Algire J. Experimental collection and transfer of embryos from bovine immunodeficiency virus (BIV) infected cattle. Theriogenology. 2001 Jan 15; 55(2):641-8.
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    181. Maxwell PH, Pugh CW, Ratcliffe PJ. Insights into the role of the von Hippel-Lindau gene product. A key player in hypoxic regulation. Exp Nephrol. 2001; 9(4):235-40.
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    182. Wykoff CC, Pugh CW, Harris AL, Maxwell PH, Ratcliffe PJ. The HIF pathway: implications for patterns of gene expression in cancer. Novartis Found Symp. 2001; 240:212-25; discussion 225-31.
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    183. Maxwell PH, Pugh CW, Ratcliffe PJ. The pVHL-hIF-1 system. A key mediator of oxygen homeostasis. Adv Exp Med Biol. 2001; 502:365-76.
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    184. Wykoff CC, Beasley NJ, Watson PH, Turner KJ, Pastorek J, Sibtain A, Wilson GD, Turley H, Talks KL, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res. 2000 Dec 15; 60(24):7075-83.
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    185. Wykoff CC, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ. Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling. Oncogene. 2000 Dec 14; 19(54):6297-305.
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    186. Ratcliffe PJ, Pugh CW, Maxwell PH. Targeting tumors through the HIF system. Nat Med. 2000 Dec; 6(12):1315-6.
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    187. Maxwell P, McCluggage WG. Audit and internal quality control in immunohistochemistry. J Clin Pathol. 2000 Dec; 53(12):929-32.
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    188. McAlinden RL, Maxwell P, Napier S, Hamilton P, Cowan CG, Lundy FT, Lamey PJ, Marley JJ. Bcl-2 expression in sequential biopsies of potentially malignant oral mucosal lesions assessed by immunocytochemistry. Oral Dis. 2000 Sep; 6(5):318-26.
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    189. Cockman ME, Masson N, Mole DR, Jaakkola P, Chang GW, Clifford SC, Maher ER, Pugh CW, Ratcliffe PJ, Maxwell PH. Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein. J Biol Chem. 2000 Aug 18; 275(33):25733-41.
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    190. Pandit JJ, Maxwell PH. New insights into the regulation of erythropoietin production. Br J Anaesth. 2000 Aug; 85(2):329-30.
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    191. Ren X, Dorrington KL, Maxwell PH, Robbins PA. Effects of desferrioxamine on serum erythropoietin and ventilatory sensitivity to hypoxia in humans. J Appl Physiol (1985). 2000 Aug; 89(2):680-6.
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    192. Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol. 2000 Aug; 157(2):411-21.
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    193. McCluggage WG, Patterson A, Maxwell P. Aggressive angiomyxoma of pelvic parts exhibits oestrogen and progesterone receptor positivity. J Clin Pathol. 2000 Aug; 53(8):603-5.
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    194. Bielanski A, Maxwell P, Simard C. Effect of bovine leukaemia virus on embryonic development and association with in vitro fertilised embryos. Vet Rec. 2000 Feb 26; 146(9):255-6.
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    195. Griffiths L, Binley K, Iqball S, Kan O, Maxwell P, Ratcliffe P, Lewis C, Harris A, Kingsman S, Naylor S. The macrophage - a novel system to deliver gene therapy to pathological hypoxia. Gene Ther. 2000 Feb; 7(3):255-62.
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    196. Johnston SD, Watson RG, Middleton D, McMillan SA, Maxwell P, Hamilton P, Love AH. Genetic, morphometric and immunohistochemical markers of latent coeliac disease. Eur J Gastroenterol Hepatol. 1999 Nov; 11(11):1283-8.
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    197. McCluggage WG, Maxwell P. Adenocarcinomas of various sites may exhibit immunoreactivity with anti-inhibin antibodies. Histopathology. 1999 Sep; 35(3):216-20.
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    198. Timms PM, Campbell S, Maxwell P, Shields DL, Danesh BJ. Tissue inhibitor of metalloproteinase-1 is not an acute-phase protein. Ann N Y Acad Sci. 1999 Jun 30; 878:500-2.
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    199. Maxwell P, van den Berg HW. Changes in the secretion of insulin-like growth factor binding proteins -2 and -4 associated with the development of tamoxifen resistance and estrogen independence in human breast cancer cell lines. Cancer Lett. 1999 May 24; 139(2):121-7.
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    200. Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999 May 20; 399(6733):271-5.
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    201. McManus DT, Patterson AH, Maxwell P, Humphreys MW, Anderson NH. Fluorescence in situ hybridisation detection of erbB2 amplification in breast cancer fine needle aspirates. Mol Pathol. 1999 Apr; 52(2):75-7.
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    202. Peacock SJ, Curtis N, Berendt AR, Bowler IC, Winearls CG, Maxwell P. Outcome following haemodialysis catheter-related Staphylococcus aureus bacteraemia. J Hosp Infect. 1999 Mar; 41(3):223-8.
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    203. McManus DT, Patterson AH, Maxwell P, Hamilton PW, Anderson NH, Caughley LM, Toner PG. Interphase cytogenetics of chromosomes 11 and 17 in fine needle aspirates of breast cancer. Hum Pathol. 1999 Feb; 30(2):137-44.
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    204. Maxwell P, Patterson AH, Jamison J, Miller K, Anderson N. Use of alcohol fixed cytospins protected by 10% polyethylene glycol in immunocytology external quality assurance. J Clin Pathol. 1999 Feb; 52(2):141-4.
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    205. Maxwell P. Carcinoembryonic antigen: cell adhesion molecule and useful diagnostic marker. Br J Biomed Sci. 1999; 56(3):209-14.
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    206. Spratt H, Boomer S, Irwin CR, Marley JJ, James JA, Maxwell P, Middleton D, Linden GJ. Cyclosporin associated gingival overgrowth in renal transplant recipients. Oral Dis. 1999 Jan; 5(1):27-31.
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    207. Pugh CW, Chang GW, Cockman M, Epstein AC, Gleadle JM, Maxwell PH, Nicholls LG, O'Rourke JF, Ratcliffe PJ, Raybould EC, Tian YM, Wiesener MS, Wood M, Wykoff CC, Yeates KM. Regulation of gene expression by oxygen levels in mammalian cells. Adv Nephrol Necker Hosp. 1999; 29:191-206.
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    208. McCluggage WG, Maxwell P, Hamilton PW, Jasani B. High metallothionein expression is associated with features predictive of aggressive behaviour in endometrial carcinoma. Histopathology. 1999 Jan; 34(1):51-5.
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    209. Maxwell P, Fitzpatrick R. End stage renal failure and assessment of health related quality of life. Qual Health Care. 1998 Dec; 7(4):182.
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    210. Wiesener MS, Turley H, Allen WE, Willam C, Eckardt KU, Talks KL, Wood SM, Gatter KC, Harris AL, Pugh CW, Ratcliffe PJ, Maxwell PH. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha. Blood. 1998 Oct 1; 92(7):2260-8.
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    211. Carmeliet P, Dor Y, Herbert JM, Fukumura D, Brusselmans K, Dewerchin M, Neeman M, Bono F, Abramovitch R, Maxwell P, Koch CJ, Ratcliffe P, Moons L, Jain RK, Collen D, Keshert E, Keshet E. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature. 1998 Jul 30; 394(6692):485-90.
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    212. McCluggage WG, Shanks JH, Whiteside C, Maxwell P, Banerjee SS, Biggart JD. Immunohistochemical study of testicular sex cord-stromal tumors, including staining with anti-inhibin antibody. Am J Surg Pathol. 1998 May; 22(5):615-9.
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    213. Maxwell P, Ratcliffe P. Regulation of expression of the erythropoietin gene. Curr Opin Hematol. 1998 May; 5(3):166-70.
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    214. Wood SM, Wiesener MS, Yeates KM, Okada N, Pugh CW, Maxwell PH, Ratcliffe PJ. Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression. J Biol Chem. 1998 Apr 3; 273(14):8360-8.
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    215. Ratcliffe PJ, O'Rourke JF, Maxwell PH, Pugh CW. Oxygen sensing, hypoxia-inducible factor-1 and the regulation of mammalian gene expression. J Exp Biol. 1998 Apr; 201(Pt 8):1153-62.
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    216. Patterson AH, McManus DT, Maxwell P. Detection of chromosomal numerical abnormalities in clinical breast tumour fine-needle aspirations by fluorescence in situ hybridisation (FISH): refinement of a method. Br J Biomed Sci. 1998 Mar; 55(1):2-7.
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    217. McCluggage WG, Ashe P, McBride H, Maxwell P, Sloan JM. Localization of the cellular expression of inhibin in trophoblastic tissue. Histopathology. 1998 Mar; 32(3):252-6.
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    218. McCluggage WG, Burton J, Maxwell P, Sloan JM. Immunohistochemical staining of normal, hyperplastic, and neoplastic adrenal cortex with a monoclonal antibody against alpha inhibin. J Clin Pathol. 1998 Feb; 51(2):114-6.
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    219. Chowdhury TA, Dyer PH, Kumar S, Gibson SP, Rowe BR, Davies SJ, Marshall SM, Morris PJ, Gill GV, Feeney S, Maxwell P, Savage D, Boulton AJ, Todd JA, Dunger D, Barnett AH, Bain SC. Association of apolipoprotein epsilon2 allele with diabetic nephropathy in Caucasian subjects with IDDM. Diabetes. 1998 Feb; 47(2):278-80.
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    220. McCluggage WG, Maxwell P, Bharucha H. Immunohistochemical detection of metallothionein and MIB1 in uterine cervical squamous lesions. Int J Gynecol Pathol. 1998 Jan; 17(1):29-35.
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    221. Gleeson CM, Sloan JM, McManus DT, Maxwell P, Arthur K, McGuigan JA, Ritchie AJ, Russell SE. Comparison of p53 and DNA content abnormalities in adenocarcinoma of the oesophagus and gastric cardia. Br J Cancer. 1998; 77(2):277-86.
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    222. Maxwell PH, Winearls CG. Recurrence of autonomous hyperparathyroidism in dialysis patients. Nephrol Dial Transplant. 1997 Oct; 12(10):2195-200.
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    223. Ratcliffe PJ, Maxwell PH, Pugh CW. Beyond erythropoietin: the oxygen sensor. Nephrol Dial Transplant. 1997 Sep; 12(9):1842-8.
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    224. Maxwell PH, Ferguson DJ, Nicholls LG, Johnson MH, Ratcliffe PJ. The interstitial response to renal injury: fibroblast-like cells show phenotypic changes and have reduced potential for erythropoietin gene expression. Kidney Int. 1997 Sep; 52(3):715-24.
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    225. McCluggage WG, Maxwell P, Sloan JM. Immunohistochemical staining of ovarian granulosa cell tumors with monoclonal antibody against inhibin. Hum Pathol. 1997 Sep; 28(9):1034-8.
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    226. Abelson J, Maxwell PH, Maxwell RJ. Do professions have a future? BMJ. 1997 Aug 16; 315(7105):382.
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    227. Heaney LG, Leggett P, Maxwell P, Bharucha H, Ennis M. A comparison of three standard methods of identifying mast cells in endobronchial biopsies in normal and asthmatic subjects. Allergy. 1997 Aug; 52(8):836-43.
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    228. Maxwell PH, Dachs GU, Gleadle JM, Nicholls LG, Harris AL, Stratford IJ, Hankinson O, Pugh CW, Ratcliffe PJ. Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):8104-9.
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    229. Maxwell P, Mendall M. Prevalence of gastrointestinal symptoms after bacterial gastroenteritis. Patients with the irritable bowel syndrome may underreport historical symptoms. BMJ. 1997 Jun 28; 314(7098):1902-3.
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    230. McCluggage WG, Maxwell P, Patterson A, Sloan JM. Immunohistochemical staining of hepatocellular carcinoma with monoclonal antibody against inhibin. Histopathology. 1997 Jun; 30(6):518-22.
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    231. Heatley M, White J, Patterson A, Maxwell P, Whiteside C, Toner P. Intermediate filament expression of ductal carcinoma cells in fine needle aspirates of the breast. Acta Cytol. 1997 May-Jun; 41(3):717-20.
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    232. Raja KB, Maxwell PH, Ratcliffe PJ, Salisbury JR, Simpson RJ, Peters TJ. Iron metabolism in transgenic mice with hypoplastic anaemia due to incomplete deficiency of erythropoietin. Br J Haematol. 1997 Feb; 96(2):248-53.
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    233. Ratcliffe PJ, Ebert BL, Firth JD, Gleadle JM, Maxwell PH, Nagao M, O'Rourke JF, Pugh CW, Wood SM. Oxygen regulated gene expression: erythropoietin as a model system. Kidney Int. 1997 Feb; 51(2):514-26.
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    234. Maxwell PH, Ferguson DJ, Nicholls LG, Iredale JP, Pugh CW, Johnson MH, Ratcliffe PJ. Sites of erythropoietin production. Kidney Int. 1997 Feb; 51(2):393-401.
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    235. McCluggage G, McBride H, Maxwell P, Bharucha H. Immunohistochemical detection of p53 and bcl-2 proteins in neoplastic and non-neoplastic endocervical glandular lesions. Int J Gynecol Pathol. 1997 Jan; 16(1):22-7.
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    236. O'Rourke JF, Dachs GU, Gleadle JM, Maxwell PH, Pugh CW, Stratford IJ, Wood SM, Ratcliffe PJ. Hypoxia response elements. Oncol Res. 1997; 9(6-7):327-32.
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    237. Heatley MK, Maxwell P, Toner PG. The immunophenotype of human decidua and extra-uterine decidual reactions. Histopathology. 1996 Nov; 29(5):437-42.
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    238. Maxwell PH, Ratcliffe PJ. The erythropoietin-producing cells. Exp Nephrol. 1996 Nov-Dec; 4(6):309-13.
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    239. Maxwell P, Hamilton PW, Sloan JM. Three-dimensional reconstruction of perineural invasion in carcinoma of the extrahepatic bile ducts. J Pathol. 1996 Oct; 180(2):142-5.
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    240. McCluggage WG, McManus D, Maxwell P, Walsh MY. T-cell-rich histiocyte-rich B-cell lymphoma of parotid gland. J Laryngol Otol. 1996 Aug; 110(8):811-3.
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    241. McCluggage WG, Buhidma M, Tang L, Maxwell P, Bharucha H. Monoclonal antibody MIB1 in the assessment of cervical squamous intraepithelial lesions. Int J Gynecol Pathol. 1996 Apr; 15(2):131-6.
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    242. Heatley M, Maxwell P, Whiteside C, Toner P. Vimentin and cytokeratin expression in nodular hyperplasia and carcinoma of the prostate. J Clin Pathol. 1995 Nov; 48(11):1031-4.
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    243. Peacock SJ, Maxwell P, Stanton A, Jeffery KJ. Two cases of infected atherosclerotic aneurysms and a comparison with infective endocarditis. Eur J Clin Microbiol Infect Dis. 1995 Nov; 14(11):1004-8.
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    244. McCluggage WG, Roddy S, Whiteside C, Burton J, McBride H, Maxwell P, Bharucha H. Immunohistochemical staining of plastic embedded bone marrow trephine biopsy specimens after microwave heating. J Clin Pathol. 1995 Sep; 48(9):840-4.
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    245. McCluggage WG, Maxwell P, McBride HA, Hamilton PW, Bharucha H. Monoclonal antibodies Ki-67 and MIB1 in the distinction of tuboendometrial metaplasia from endocervical adenocarcinoma and adenocarcinoma in situ in formalin-fixed material. Int J Gynecol Pathol. 1995 Jul; 14(3):209-16.
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    246. Heatley M, Maxwell P, Whiteside C, Toner P. Cytokeratin intermediate filament expression in benign and malignant breast disease. J Clin Pathol. 1995 Jan; 48(1):26-32.
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    247. Ratcliffe PJ, Ebert BL, Ferguson DJ, Firth JD, Gleadle JM, Maxwell PH, Pugh CW. Regulation of the erythropoietin gene. Nephrol Dial Transplant. 1995; 10 Suppl 2:18-27.
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    248. Tay A, Maxwell P, Li ZG, Goldberg H, Skorecki K. Cytosolic phospholipase A2 gene expression in rat mesangial cells is regulated post-transcriptionally. Biochem J. 1994 Dec 1; 304 ( Pt 2):417-22.
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    249. McManus DT, Yap EP, Maxwell P, Russell SE, Toner PG, McGee JO. p53 expression, mutation, and allelic deletion in ovarian cancer. J Pathol. 1994 Nov; 174(3):159-68.
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    250. Heatley M, Whiteside C, Maxwell P, Toner PG. Correspondence Re: WM Hanna, Kahn HJ, and J-AW Chapman. The correlation of Ki-67 growth factor and ERICA in breast cancer. Mod Pathol 5:220, 1992. Mod Pathol. 1994 Oct; 7(8):889-90.
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    251. Maxwell PH, Ferguson DJ, Osmond MK, Pugh CW, Heryet A, Doe BG, Johnson MH, Ratcliffe PJ. Expression of a homologously recombined erythopoietin-SV40 T antigen fusion gene in mouse liver: evidence for erythropoietin production by Ito cells. Blood. 1994 Sep 15; 84(6):1823-30.
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    252. Pugh CW, Ebert BL, Ebrahim O, Maxwell PH, Ratcliffe PJ. Analysis of cis-acting sequences required for operation of the erythropoietin 3' enhancer in different cell lines. Ann N Y Acad Sci. 1994 Apr 15; 718:31-9; discussion 39-40.
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    253. Maxwell PH, Osmond MK, Pugh CW, Heryet A, Nicholls LG, Tan CC, Doe BG, Ferguson DJ, Johnson MH, Ratcliffe PJ. Erythropoietin-producing cells in transgenic mice expressing SV40 large T antigen directed by erythropoietin control sequences. Ann N Y Acad Sci. 1994 Apr 15; 718:356-8.
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    254. Tay A, Maxwell P, Li Z, Goldberg H, Skorecki K. Isolation of promoter for cytosolic phospholipase A2 (cPLA2). Biochim Biophys Acta. 1994 Apr 6; 1217(3):345-7.
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    255. Goldberg H, Maxwell P, Hack N, Skorecki K. Reduced phospholipase A2 activity is not accompanied by reduced arachidonic acid release. Biochem Biophys Res Commun. 1994 Jan 14; 198(1):220-7.
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    256. Maxwell PH, Osmond MK, Pugh CW, Heryet A, Nicholls LG, Tan CC, Doe BG, Ferguson DJ, Johnson MH, Ratcliffe PJ. Identification of the renal erythropoietin-producing cells using transgenic mice. Kidney Int. 1993 Nov; 44(5):1149-62.
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    257. Maxwell P, Davis RI, Sloan JM. Carcinoembryonic antigen (CEA) in benign and malignant epithelium of the gall bladder, extrahepatic bile ducts, and ampulla of Vater. J Pathol. 1993 May; 170(1):73-6.
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    258. Heatley M, Whiteside C, Maxwell P, Toner P. Vimentin expression in benign and malignant breast epithelium. J Clin Pathol. 1993 May; 46(5):441-5.
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    259. Heatley M, Maxwell P, Whiteside C, Toner PG. C-erbB-2 oncogene product expression depends on tumour type and is related to oestrogen receptor and lymph node status in human breast carcinoma. Pathol Res Pract. 1993 Apr; 189(3):261-6.
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    260. Maxwell PH, Pugh CW, Ratcliffe PJ. Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism. Proc Natl Acad Sci U S A. 1993 Mar 15; 90(6):2423-7.
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    261. Williamson K, Halliday I, Hamilton P, Ruddell J, Varma M, Maxwell P, Crockard A, Rowlands B. In vitro BrdUrd incorporation of colorectal tumour tissue. Cell Prolif. 1993 Mar; 26(2):115-24.
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    262. Paterson-Brown S, Chappatte OA, Clark SK, Wright A, Maxwell P, Taub NA, Raju KS. The significance of cone biopsy resection margins. Gynecol Oncol. 1992 Aug; 46(2):182-5.
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    263. Kottke TE, Solberg LI, Brekke ML, Conn SA, Maxwell P, Brekke MJ. A controlled trial to integrate smoking cessation advice into primary care practice: Doctors Helping Smokers, Round III. J Fam Pract. 1992 Jun; 34(6):701-8.
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    264. Keeling J, Maxwell P, Gardner RC. Nucleotide sequence of the promoter region from kiwifruit actinidin genes. Plant Mol Biol. 1990 Nov; 15(5):787-8.
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    265. Crosbie J, Humphreys WG, Maxwell M, Maxwell P, Cameron CH, Toner PG. Gastric paraganglioma: an immunohistological and ultrastructural case study. J Submicrosc Cytol Pathol. 1990 Jul; 22(3):401-8.
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    266. Kottke TE, Solberg LI, Conn S, Maxwell P, Thomasberg M, Brekke ML, Brekke MJ. A comparison of two methods to recruit physicians to deliver smoking cessation interventions. Arch Intern Med. 1990 Jul; 150(7):1477-81.
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    267. Walsh DJ, Matthews JA, Denmeade R, Maxwell P, Davidson M, Walker MR. Monoclonal antibodies to proteins from cocksfoot grass (Dactylis glomerata) pollen: isolation and N-terminal sequence of a major allergen. Int Arch Allergy Appl Immunol. 1990; 91(4):419-25.
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    268. Davis RI, Sloan JM, Hood JM, Maxwell P. Carcinoma of the extrahepatic biliary tract: a clinicopathological and immunohistochemical study. Histopathology. 1988 Jun; 12(6):623-31.
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