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Melvin H. Van Woert

TitlePROFESSOR
InstitutionMount Sinai
DepartmentNeurology
Address5 East 98th Street
7th Floor
New York NY 10029
Phone212-241-7076
Fax212-860-4952
    Other Positions
    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentPharmacology and Systems Therapeutics


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Anderson MC, Chung EY, Van Woert MH. The effects of inferior olive lesion on strychnine seizure. Brain Res Bull. 1990 Oct; 25(4):599-603.
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    2. Chung E, Dvorozniak MT, Van Woert MH, Li HC. Regional distribution of calcium/calmodulin-dependent phosphatase activity of calcineurin in rat brain. Res Commun Chem Pathol Pharmacol. 1989 Jun; 64(3):357-71.
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    3. Hunter C, Chung E, Van Woert MH. Age-dependent changes in brain glycine concentration and strychnine-induced seizures in the rat. Brain Res. 1989 Mar 20; 482(2):247-51.
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    4. Lee DH, Mendoza M, Dvorozniak MT, Chung E, van Woert MH, Yahr MD. Platelet monoamine oxidase in Parkinson patients: effect of L-deprenyl therapy. J Neural Transm Park Dis Dement Sect. 1989; 1(3):189-94.
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    5. Anderson MC, Chung E, Van Woert MH. Strychnine seizure potentiation by azaspirodecanedione anxiolytics in rats. Eur J Pharmacol. 1988 Oct 18; 155(3):279-83.
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    6. Anderson MC, Chung EY, Van Woert MH. Effect of inferior olive lesion on seizure threshold in the rat. Life Sci. 1987 Jun 15; 40(24):2367-75.
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    7. Chung E, Li HC, Van Woert MH, Chan WS. Ca2+/calmodulin-dependent phosphoprotein phosphatase activity of calcineurin in rat striatum: effect of kainic acid lesions. Neuropharmacology. 1987 Jun; 26(6):633-6.
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    8. Heyer EJ, Chung EY, Van Woert M, Parise J. Characterization of dopamine receptors on neurons grown in primary dissociated cell culture from ventral mesencephalon of mouse. Brain Res. 1986 Jul 2; 377(1):54-62.
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    9. Chung EY, Van Woert MH. DDT myoclonus: site of "myoclonus center" in the brain. Adv Neurol. 1986; 43:569-75.
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    10. Chung EY, Van Woert MH. Urea myoclonus: possible involvement of glycine. Adv Neurol. 1986; 43:565-8.
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    11. Fahn S, Marsden CD, Van Woert MH. Definition and classification of myoclonus. Adv Neurol. 1986; 43:1-5.
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    12. Van Woert MH, Chung EY. Possible mechanisms of action of valproic acid in myoclonus. Adv Neurol. 1986; 43:653-60.
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    13. Van Woert MH, Rosenbaum D, Chung EY. Biochemistry and therapeutics of posthypoxic myoclonus. Adv Neurol. 1986; 43:171-81.
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    14. Chung E, Yocca F, Van Woert MH. Urea-induced myoclonus: medullary glycine antagonism as mechanism of action. Life Sci. 1985 Mar 18; 36(11):1051-8.
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    15. Van Woert MH. Orphan Drug Act. Prog Clin Biol Res. 1985; 197:7-9.
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    16. Van Woert MH. Introduction-Current activities and future goals of orphan disease agencies. Prog Clin Biol Res. 1985; 197:3-6.
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    17. Hauck FP, Chung EY, Van Woert MH. Academic center approaches to orphan drug research and development. Prog Clin Biol Res. 1985; 197:115-22.
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    18. Van Woert MH. Problems associated with developing orphan drugs into available therapy. Prog Clin Biol Res. 1985; 197:171-3.
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    19. Chung E, Van Woert MH. DDT myoclonus: sites and mechanism of action. Exp Neurol. 1984 Aug; 85(2):273-82.
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    20. Van Woert MH, Magnussen I, Rosenbaum D, Chung E. Fluoxetine in the treatment of intention myoclonus. Clin Neuropharmacol. 1983 Mar; 6(1):49-54.
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    21. Van Woert MH. Myoclonus and L-5-hydroxytryptophan (L-5HTP). Prog Clin Biol Res. 1983; 127:43-52.
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    22. Mytilineou C, Cohen G, Dembiec-Cohen D, Van Woert M, Hwang E. Explant cultures of dog substantia nigra and striatum: a model for the study of nigro-striatal dopamine neurons. J Neural Transm Suppl. 1983; 19:37-51.
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    23. Feit H, Kirkpatrick J, Van Woert MH, Pandian G. Myoclonus, ataxia, and hypoventilation: response to L-5-hydroxytryptophan. Neurology. 1983 Jan; 33(1):109-12.
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    24. Van Woert MH. Scientists' viewpoints on orphan drug problems and possible solutions. Prog Clin Biol Res. 1983; 127:187-95.
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    25. Van Woert MH, Magnussen I, Lowe YH, Hwang EC. Study of serotonin in neuropsychiatric disorders. J Histochem Cytochem. 1982 Aug; 30(8):824-7.
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    26. Magnussen I, Van Woert MH. Human pharmacokinetics of long term 5-hydroxytryptophan combined with decarboxylase inhibitors. Eur J Clin Pharmacol. 1982; 23(1):81-6.
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    27. van Woert MH, Rosenbaum D, Enna SJ. Overview of pharmacological approaches to therapy for Tourette syndrome. Adv Neurol. 1982; 35:369-75.
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    28. Chung Hwang E, Van Woert MH. p,p'-DDT-induced alterations in brain serotonin metabolism. Neurotoxicology. 1981 Dec; 2(4):649-57.
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    29. Magnussen I, Jensen TS, Rand JH, Van Woert MH. Plasma accumulation of metabolism of orally administered single dose L-5-hydroxytryptophan in man. Acta Pharmacol Toxicol (Copenh). 1981 Sep; 49(3):184-9.
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    30. Hwang EC, Plaitakis A, Magnussen I, Van Woert MH. Relationship of inferior olive-climbing fibers to p,p'-DDT-induced myoclonus in rats. Neurosci Lett. 1981 Jun 12; 24(1):103-8.
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    31. Hwang EC, Van Woert MH. Role of prostaglandins in the antimyoclonic action of clonazepam. Eur J Pharmacol. 1981 Apr 24; 71(1):161-4.
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    32. Van Woert MH. Orphan drugs: proposed legislative help. N Engl J Med. 1981 Jan 22; 304(4):235.
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    33. Plaitakis A, Nicklas WJ, Van Woert MH, Hwang EC, Berl S. Uptake and metabolism of serotonin and amino acids in thiamine deficiency. Adv Exp Med Biol. 1981; 133:391-416.
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    34. Hwang EC, Van Woert MH. Comparative effects of various serotonin releasing agents in mice. Biochem Pharmacol. 1980 Dec 1; 29(23):3163-7.
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    35. Sternberg EM, Van Woert MH, Young SN, Magnussen I, Baker H, Gauthier S, Osterland CK. Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa. N Engl J Med. 1980 Oct 2; 303(14):782-7.
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    36. Van Woert MH. Drugs of limited commercial value. N Engl J Med. 1980 Jul 10; 303(2):114.
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    37. Hwang EC, Magnussen I, Van Woert MH. Effects of chronic fluoxetine administration on serotonin metabolism. Res Commun Chem Pathol Pharmacol. 1980 Jul; 29(1):79-98.
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    38. Chung Hwang E, Van Woert MH. Comparative effects of substituted phenylethylamines on brain serotonergic mechanisms. J Pharmacol Exp Ther. 1980 May; 213(2):254-60.
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    39. Hwang EC, Van Woert MH. Acute versus chronic effects of serotonin uptake blockers on potentiation of the "serotonin syndrome". Commun Psychopharmacol. 1980; 4(2):161-7.
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    40. Van Woert MH, Plaitakis A, Hwang EC, Berl S. Effect of thiamine deficiency on brain serotonin turnover. Brain Res. 1979 Dec 21; 179(1):103-10.
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    41. Chung Hwang E, Van Woert MH. Antimyoclonic action of clonazepam: the role of serotonin. Eur J Pharmacol. 1979 Nov 23; 60(1):31-40.
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    42. Hwang EC, Van Woert MH. Effect of valproic and acid on serotonin metabolism. Neuropharmacology. 1979 Apr; 18(4):391-7.
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    43. Hwang EC, Van Woert MH. Behavioral and biochemical effects of para-methoxyphenylethylamine. Res Commun Chem Pathol Pharmacol. 1979 Mar; 23(3):419-31.
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    44. Hwang EC, Van Woert MH. Behavioral and biochemical actions of p-chlorophenylethylamine (p-CPEA) in mice. Life Sci. 1979 Feb 12; 24(7):595-601.
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    45. Hwang EC, Van Woert MH. DDT-induced myoclonus: serotonin and alpha noradrenergic interaction. Res Commun Chem Pathol Pharmacol. 1979 Feb; 23(2):257-66.
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    46. Van Woert MH, Rosenbaum D. L-5-hydroxytryptophan therapy in myoclonus. Adv Neurol. 1979; 26:107-15.
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    47. Hwang EC, van Woert MH. Serotonin-norepinephrine interactions in the tremorolytic actions of phenoxybenzamine and trazodone. Pharmacol Biochem Behav. 1979 Jan; 10(1):27-9.
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    48. Van Woert MH, Hwang EC. Animal models of myoclonus. Adv Neurol. 1979; 26:173-80.
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    49. Hwang EC, Van Woert MH. p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus. Neurology. 1978 Oct; 28(10):1020-5.
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    50. Plaitakis A, Van Woert MH, Hwang EC, Berl S. The effect of acute thiamine deficiency on brain tryptophan, serotonin and 5-hydroxyindoleacetic acid. J Neurochem. 1978 Oct; 31(4):1087-9.
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    51. Van Woert MH. Profitable and nonprofitable drugs. N Engl J Med. 1978 Apr 20; 298(16):903-6.
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    52. Ambani LM, Jhung JW, Edelstein LM, Van Woert MH. Quantification of melanin in hepatic and cardiac lipofuscin. Experientia. 1977 Mar 15; 33(3):296-8.
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    53. Van Woert MH, Yip LC, Balis ME. Purine phosphoribosyltransferase in gilles de la Tourette syndrome. N Engl J Med. 1977 Jan 27; 296(4):210-2.
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    54. Van Woert MH, Rosenbaum D, Howieson J, Bowers MB. Long-term therapy of myoclonus and other neurologic disorders with L-5-hydroxytryptophan and carbidopa. N Engl J Med. 1977 Jan 13; 296(2):70-5.
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    55. Van Woert MH, Rosenbaum D. Chronic cerebellar stimulation. Arch Neurol. 1977 Jan; 34(1):58.
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    56. Sethy VH, Roth RH, Walters JR, Marini J, Van Woert MH. Effect of anesthetic doses of gamma-hydroxybutyrate on the acetylcholine content of rat brain. Naunyn Schmiedebergs Arch Pharmacol. 1976 Oct; 295(1):9-14.
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    57. Extein I, Van Woert M, Roth RH, Bowers MB. 14C-homovanillic acid in the cerebrospinal fluid of parkinsonian patients after intravenous 14C-L-dopa. Biol Psychiatry. 1976 Apr; 11(2):227-32.
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    58. Van Woert MH, Jutkowitz R, Rosenbaum D, Bowers MB. Gilles de la Tourette's syndrome: biochemical approaches. Res Publ Assoc Res Nerv Ment Dis. 1976; 55:459-65.
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    59. Van Woert MH, Jutkowitz R, Rosenbaum D, Bowers MB. Serotonin and myoclonus. Monogr Neural Sci. 1976; 3:71-80.
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    60. Ambani LM, Van Woert MH, Murphy S. Brain peroxidase and catalase in Parkinson disease. Arch Neurol. 1975 Feb; 32(2):114-8.
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    61. Van Woert MH, Sethy VH. Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. Neurology. 1975 Feb; 25(2):135-40.
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    62. Sethy VH, Van Woert MH. Regulation of striatal acetylcholine concentration by dopamine receptors. Nature. 1974 Oct 11; 251(5475):529-30.
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    63. Van Woert MH. Proceedings: Phenothiazine drugs and melanin synthesis. Psychopharmacol Bull. 1974 Oct; 10(4):41-2.
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    64. Liu YP, Ambani LM, Van Woert MH. L-dihydroxyphenylalanine: effect on levels of free amino acids in rat liver. Proc Soc Exp Biol Med. 1974 Oct; 147(1):154-7.
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    65. Sethy VH, Van Woert MH. Brain acetylcholine and cholinesterase: effect of phenothiazines and physostigmine interaction in rats. J Neurochem. 1974 Jul; 23(1):105-9.
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    66. Van Woert MH, Sethy VH. Letter: Treatment of post-anoxic intention myoclonus. Lancet. 1974 Jun 22; 1(7869):1285.
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    67. Brown WA, Krieger DT, Van Woert MH, Ambani LM. Dissociation of growth hormone and cortisol release following apomorphine. J Clin Endocrinol Metab. 1974 Jun; 38(6):1127-30.
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    68. Sethy VH, VAN Woert MH. Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists. Res Commun Chem Pathol Pharmacol. 1974 May; 8(1):13-28.
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    69. Van Woert MH, Sethy VH, Ambani LM. Effect of phenothiazines on central cholinergic activity. Adv Biochem Psychopharmacol. 1974; 9(0):707-15.
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    70. Van Woert MH, Ambani LM. Biochemistry of neuromelanin. Adv Neurol. 1974; 5:215-23.
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    71. Burrow GN, Spaulding SW, Donabedian R, Van Woert M, Ambani L. The effect of L-DOPA on the hypothalamic-pituitary-thyroid axis. Adv Neurol. 1974; 5:489-93.
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    72. Van Woert MH, Mueller PS, Ambani LM, Rathey U. Abnormal insulin secretion in Parkinson's disease before and during L-dihydroxyphenylalanine (L-dopa) therapy. J Endocrinol. 1973 Dec; 59(3):523-34.
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    73. Ambani LM, Van Woert MH, Bowers MB. Physostigmine effects on phenothiazine-induced extrapyramidal reactions. Arch Neurol. 1973 Dec; 29(6):444-6.
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    74. Sethy VH, Van Woert MH. Antimuscarinic drugs--effect on brain acetylcholine and tremors in rats. Biochem Pharmacol. 1973 Nov 1; 22(21):2685-91.
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    75. Sethy VH, Roth RH, Kuhar MJ, Van Woert MH. Choline and acetylcholine: regional distribution and effect of degeneration of cholinergic nerve terminals in the rat hippocampus. Neuropharmacology. 1973 Sep; 12(9):819-23.
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    76. Brown WA, Van Woert MH, Ambani LM. Effect of apomorphine on growth hormone release in humans. J Clin Endocrinol Metab. 1973 Sep; 37(3):463-5.
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    77. Van Woert MH, Ambani LM. Lithium and levodopa in parkinsonism. Lancet. 1973 Jun 16; 1(7816):1390-1.
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    78. Sethy VH, Kuhar MJ, Roth RH, Van Woert MH, Aghajanian GK. Cholinergic neurons: effect of acute septal lesion on acetylcholine and choline content of rat hippocampus. Brain Res. 1973 Jun 15; 55(2):481-4.
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    79. Ambani LM, Van Woert MH. Start hesitation--a side effect of long-term levodopa therapy. N Engl J Med. 1973 May 24; 288(21):1113-5.
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    80. Van Woert MH, Korb F. Effect of x-irradiation on melanosomal tyrosinase activity. Radiat Res. 1973 Mar; 53(3):435-43.
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    81. Ambani LM, Van Woert MH. Catalase and peroxidase in human brain. Trans Am Neurol Assoc. 1973; 98:7-10.
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    82. Sethy VH, Van Woert MH. Effect of L-DOPA on brain acetylcholine and choline in rats. Neuropharmacology. 1973 Jan; 12(1):27-31.
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    83. Van Woert MH, Ambani LM, Levine RJ. Clinical effects of para-chlorophenylalanine in Parkinson's disease. Dis Nerv Syst. 1972 Dec; 33(12):777-80.
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    84. Bowers MB, Van Woert MH. The probenecid test in Parkinson's disease. Lancet. 1972 Oct 28; 2(7783):926-7.
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    85. Ambrani LM, Van Woert MH. Modification of the tremorigenic activity of physostigmine. Br J Pharmacol. 1972 Oct; 46(2):344-7.
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    86. Liu YP, Ambani LM, Van Woert MH. L-dihydroxyphenylalanine: effect on levels of amino acids in rat brain. J Neurochem. 1972 Sep; 19(9):2237-9.
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    87. Spaulding SW, Burrow GN, Donabedian R, van Woert M. L-DOPA suppression of thyrotropin-releasing hormone response in man. J Clin Endocrinol Metab. 1972 Jul; 35(1):182-5.
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    88. Haworth JC, Dilling LA, Van Woert M. Blood glucose determination in infants and children. The reflectance meter-enzyme test strip system. Am J Dis Child. 1972 May; 123(5):469-71.
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    89. Van Woert MH. Low pyridoxine diet in parkinsonism. JAMA. 1972 Feb 28; 219(9):1211.
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    90. Bowers MB, Van Woert M, Davis L. Sexual behavior during L-dopa treatment for Parkinsonism. Am J Psychiatry. 1971 Jun; 127(12):1691-3.
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    91. Van Woert MH, Weintraub MI. Predicting the response to levodopa. Lancet. 1971 May 15; 1(7707):1015-6.
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    92. Van Woert MH, Korb F, Prasad KN. Regulation of tyrosinase activity in mouse melanoma and skin by changes in melanosomal membrane permeability. J Invest Dermatol. 1971 May; 56(5):343-8.
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    93. Van Woert MH, Mueller PS. Glucose, insulin, and free fatty acid metabolism in Parkinson's disease treated with levodopa. Clin Pharmacol Ther. 1971 Mar-Apr; 12(2):360-7.
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    94. Van Woert MH. Phenylalanine and tyrosine metabolism in Parkinson's disease treated with levodopa. Clin Pharmacol Ther. 1971 Mar-Apr; 12(2):368-75.
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    95. Weintraub MI, Van Woert MH. Reversal by levodopa of cholinergic hypersensitivity in Parkinson's disease. N Engl J Med. 1971 Feb 25; 284(8):412-5.
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    96. Vaidya RA, Vaidya AB, Van Woert MH, Kase NG. Galactorrhea and Parkinson-like syndrome: an adverse effect of alpha-methyldopa. Metabolism. 1970 Dec; 19(12):1068-70.
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    97. Weintraub MI, Gaasterland D, Van Woert MH. Pupillary effects of levodopa therapy. Development of anisocoria in latent Horner's syndrome. N Engl J Med. 1970 Jul 16; 283(3):120-3.
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    98. Van Woert MH. Pharmacodynamics of 3, 4-dihydroxyphenylalanine (Dopa) in Parkinson's disease. Conn Med. 1970 Jun; 34(6):401-5.
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    99. Van Woert MH. Effect of phenothiazines on melanoma tyrosinase activity. J Pharmacol Exp Ther. 1970 Jun; 173(2):256-64.
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    100. van Woert MH, Bowers MB. Homovanillic acid (HVA) and 5-hydroxyindoleacetic acid (5HIAA) during L-dopa therapy of Parkinson's disease. Neurology. 1970 Apr; 20(4):377.
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    101. Weintraub MI, Gaasterland D, van Woert M. L-dopa-induced anisocoria in latent Horner's syndrome. Neurology. 1970 Apr; 20(4):417.
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    102. Van Woert MH, Heninger G, Rathey U, Bowers MB. L-dopa in senile dementia. Lancet. 1970 Mar 14; 1(7646):573-4.
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    103. Van Woert MH, Korb F. Effect of whole-body x-irradiation on tyrosine hydroxylase and catecholamine levels. Life Sci. 1970 Feb 15; 9(4):227-32.
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    104. van Woert MH, Bowers MB. The effect of L-dopa on monoamine metabolites in Parkinson's disease. Experientia. 1970; 26(2):161-3.
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    105. Van Woert MH, Palmer SH. Inhibition of the growth of mouse melanoma by chlorpromazine. Cancer Res. 1969 Nov; 29(11):1952-5.
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    106. Prasad KN, Van Woert MH. Radioprotective action of dihydroxyphenylethylamine (Dopamine) on whole-body x-irradiated rats. Radiat Res. 1969 Feb; 37(2):305-15.
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    107. Van Woert MH. Reduced nicotinamide-adenine dinucleotide oxidation by melanin: inhibition by phenothiazines. Proc Soc Exp Biol Med. 1968 Oct; 129(1):165-71.
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    108. Van Woert MH. Isolation of chlorpromazine pigments in man. Nature. 1968 Sep 7; 219(5158):1054-6.
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    109. Van Woert MH. Oxidation of reduced nicotinamide adenine dinucleotide by melanin. Life Sci. 1967 Dec 15; 6(24):2605-12.
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    110. Van Woert MH, Nicholson A, Cotzias GC. Mitochondrial functions of polymelanosomes. Comp Biochem Physiol. 1967 Aug; 22(2):477-85.
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    111. Van Woert MH. Proteus mirabilis enterocolitis following abdominal irradiation. Report of a case. Am J Dig Dis. 1967 Jul; 12(7):737-41.
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    112. Van Woert MH, Prasad KN, Borg DC. Spectroscopic studies of substantia nigra pigment in human subjects. J Neurochem. 1967 Jul; 14(7):707-16.
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    113. Cotzias GC, Van Woert MH, Schiffer LM. Aromatic amino acids and modification of parkinsonism. N Engl J Med. 1967 Feb 16; 276(7):374-9.
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    114. Prasad KN, Van Woert MH. Dopamine protects mice against whole-body irradiation. Science. 1967 Jan 27; 155(3761):470-2.
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    115. Van Woert MH, Cotzias GC. Anion inhibition of monoamine oxidase. Biochem Pharmacol. 1966 Mar; 15(3):275-85.
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    116. Van Woert MH, Nicholson AR, Cotzias GC. Functional similarities between the cytoplasmic organelles of melanocytes and the mitochondria of hepatocytes. Nature. 1965 Nov 20; 208(5012):810-1.
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    117. Cotzias GC, Van Woert MH. Manganese poisoning--new insights. Rev Neuropsiquiatr. 1964 Dec; 27(4):392-404.
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    118. BRAUCHER RE, VAN WOERT M, KIRSNER JB. Esophageal hiatus hernia. Postgrad Med. 1962 Apr; 31:325-31.
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    119. VAN WOERT MH, KIRSNER JB. Idiopathic jaundice of pregnancy. Gastroenterology. 1961 May; 40:633-5.
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    120. VAN WOERT M, KAPPAS A. Major muscle rupture in rheumatoid arthritis. Ill Med J. 1960 Jan; 117:23-5.
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