Keywords
Last Name
Institution

Arthur I. Cederbaum

TitlePROFESSOR
InstitutionMount Sinai
DepartmentPharmacology and Systems Therapeutics
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Wu D, Cederbaum AI. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK. Redox Biol. 2013; 1(1):552-65.
      View in: PubMed
    2. Lu Y, Ward SC, Cederbaum AI. Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver. Alcohol. 2013 Aug; 47(5):353-7.
      View in: PubMed
    3. Wang X, Wu D, Yang L, Gan L, Cederbaum AI. Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1a in vivo. Free Radic Biol Med. 2013 Oct; 63:175-86.
      View in: PubMed
    4. Forsyth CB, Voigt RM, Shaikh M, Tang Y, Cederbaum AI, Turek FW, Keshavarzian A. Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability. Am J Physiol Gastrointest Liver Physiol. 2013 Jul 15; 305(2):G185-95.
      View in: PubMed
    5. Cederbaum AI. Nrf2 and Antioxidant Defense Against CYP2E1 Toxicity. Subcell Biochem. 2013; 67:105-30.
      View in: PubMed
    6. Cederbaum AI. Alcohol metabolism. Clin Liver Dis. 2012 Nov; 16(4):667-85.
      View in: PubMed
    7. Wu D, Wang X, Zhou R, Yang L, Cederbaum AI. Alcohol steatosis and cytotoxicity: the role of cytochrome P4502E1 and autophagy. Free Radic Biol Med. 2012 Sep 15; 53(6):1346-57.
      View in: PubMed
    8. Yang L, Wu D, Wang X, Cederbaum AI. Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver. Free Radic Biol Med. 2012 Sep 1; 53(5):1170-80.
      View in: PubMed
    9. Lu Y, Zhang XH, Cederbaum AI. Ethanol induction of CYP2A5: role of CYP2E1-ROS-Nrf2 pathway. Toxicol Sci. 2012 Aug; 128(2):427-38.
      View in: PubMed
    10. An L, Wang X, Cederbaum AI. Cytokines in alcoholic liver disease. Arch Toxicol. 2012 Sep; 86(9):1337-48.
      View in: PubMed
    11. Cederbaum AI. CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment. Drug Metabol Drug Interact. 2012; 27(3):125-44.
      View in: PubMed
    12. Wang X, Wu D, Yang L, Cederbaum AI. Hepatotoxicity mediated by pyrazole (cytochrome P450 2E1) plus tumor necrosis factor alpha treatment occurs in c-Jun N-terminal kinase 2-/- but not in c-Jun N-terminal kinase 1-/- mice. Hepatology. 2011 Nov; 54(5):1753-66.
      View in: PubMed
    13. Cederbaum AI, Yang L, Wang X, Wu D. CYP2E1 Sensitizes the Liver to LPS- and TNF a-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases. Int J Hepatol. 2012; 2012:582790.
      View in: PubMed
    14. Andreo U, Elkind J, Blachford C, Cederbaum AI, Fisher EA. Role of superoxide radical anion in the mechanism of apoB100 degradation induced by DHA in hepatic cells. FASEB J. 2011 Oct; 25(10):3554-60.
      View in: PubMed
    15. Cederbaum AI. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity. Dig Dis. 2010; 28(6):802-11.
      View in: PubMed
    16. Yang L, Wu D, Wang X, Cederbaum AI. Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1-JNK1 pathway in HepG2 cells. Free Radic Biol Med. 2011 Jul 1; 51(1):185-96.
      View in: PubMed
    17. Lu Y, Zhuge J, Wu D, Cederbaum AI. Ethanol induction of CYP2A5: permissive role for CYP2E1. Drug Metab Dispos. 2011 Feb; 39(2):330-6.
      View in: PubMed
    18. Wu D, Wang X, Zhou R, Cederbaum A. CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophagy in HepG2 E47 cells. Biochem Biophys Res Commun. 2010 Nov 5; 402(1):116-22.
      View in: PubMed
    19. Lu Y, Wu D, Wang X, Ward SC, Cederbaum AI. Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radic Biol Med. 2010 Nov 15; 49(9):1406-16.
      View in: PubMed
    20. Wu D, Cederbaum A. Activation of ASK-1 and downstream MAP kinases in cytochrome P4502E1 potentiated tumor necrosis factor alpha liver injury. Free Radic Biol Med. 2010 Aug 1; 49(3):348-60.
      View in: PubMed
    21. Cederbaum AI. Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury. World J Gastroenterol. 2010 Mar 21; 16(11):1366-76.
      View in: PubMed
    22. Lu Y, Cederbaum AI. CYP2E1 potentiation of LPS and TNFa-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases, and mitochondrial dysfunction. Genes Nutr. 2010 Jun; 5(2):149-67.
      View in: PubMed
    23. Cederbaum A. Nrf2 and antioxidant defense against CYP2E1 toxicity. Expert Opin Drug Metab Toxicol. 2009 Oct; 5(10):1223-44.
      View in: PubMed
    24. Wang X, Lu Y, Xie B, Cederbaum AI. Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase. Free Radic Biol Med. 2009 Sep 1; 47(5):518-28.
      View in: PubMed
    25. Cederbaum AI, Lu Y, Wu D. Role of oxidative stress in alcohol-induced liver injury. Arch Toxicol. 2009 Jun; 83(6):519-48.
      View in: PubMed
    26. Wu D, Cederbaum AI. Oxidative stress and alcoholic liver disease. Semin Liver Dis. 2009 May; 29(2):141-54.
      View in: PubMed
    27. Wu D, Xu C, Cederbaum A. Role of nitric oxide and nuclear factor-kappaB in the CYP2E1 potentiation of tumor necrosis factor alpha hepatotoxicity in mice. Free Radic Biol Med. 2009 Feb 15; 46(4):480-91.
      View in: PubMed
    28. Caro AA, Evans KL, Cederbaum AI. CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells. Toxicology. 2009 Jan 31; 255(3):171-6.
      View in: PubMed
    29. Zhuge J, Cederbaum AI. Inhibition of the mitochondrial permeability transition by cyclosporin A prevents pyrazole plus lipopolysaccharide-induced liver injury in mice. Free Radic Biol Med. 2009 Feb 1; 46(3):406-13.
      View in: PubMed
    30. Lu Y, Gong P, Cederbaum AI. Pyrazole induced oxidative liver injury independent of CYP2E1/2A5 induction due to Nrf2 deficiency. Toxicology. 2008 Oct 30; 252(1-3):9-16.
      View in: PubMed
    31. Lu Y, Zhuge J, Wang X, Bai J, Cederbaum AI. Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice. Hepatology. 2008 May; 47(5):1483-94.
      View in: PubMed
    32. Wang X, Cederbaum AI. S-adenosyl-L-methionine decreases the elevated hepatotoxicity induced by Fas agonistic antibody plus acute ethanol pretreatment in mice. Arch Biochem Biophys. 2008 Sep 1; 477(1):1-11.
      View in: PubMed
    33. Wu D, Cederbaum A. Cytochrome P4502E1 sensitizes to tumor necrosis factor alpha-induced liver injury through activation of mitogen-activated protein kinases in mice. Hepatology. 2008 Mar; 47(3):1005-17.
      View in: PubMed
    34. Wu D, Cederbaum AI. Development and properties of HepG2 cells that constitutively express CYP2E1. Methods Mol Biol. 2008; 447:137-50.
      View in: PubMed
    35. Lu Y, Cederbaum AI. CYP2E1 and oxidative liver injury by alcohol. Free Radic Biol Med. 2008 Mar 1; 44(5):723-38.
      View in: PubMed
    36. Donohue TM, Cederbaum AI, French SW, Barve S, Gao B, Osna NA. Role of the proteasome in ethanol-induced liver pathology. Alcohol Clin Exp Res. 2007 Sep; 31(9):1446-59.
      View in: PubMed
    37. Jimenez-Lopez JM, Wu D, Cederbaum AI. Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells. Toxicol In Vitro. 2008 Feb; 22(1):106-15.
      View in: PubMed
    38. Lu Y, Cederbaum A. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin. Free Radic Biol Med. 2007 Oct 1; 43(7):1061-75.
      View in: PubMed
    39. Zhuge J, Cederbaum AI. Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes. Arch Biochem Biophys. 2007 Oct 15; 466(2):177-85.
      View in: PubMed
    40. Dey A, Cederbaum AI. Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice. Hepatology. 2007 Jun; 45(6):1355-65.
      View in: PubMed
    41. Dey A, Caro AA, Cederbaum AI. S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury. Am J Physiol Gastrointest Liver Physiol. 2007 Jul; 293(1):G91-103.
      View in: PubMed
    42. Dey A, Cederbaum AI. Geldanamycin, an inhibitor of Hsp90 increases cytochrome P450 2E1 mediated toxicity in HepG2 cells through sustained activation of the p38MAPK pathway. Arch Biochem Biophys. 2007 May 15; 461(2):275-86.
      View in: PubMed
    43. Kessova IG, Cederbaum AI. Mitochondrial alterations in livers of Sod1-/- mice fed alcohol. Free Radic Biol Med. 2007 May 15; 42(10):1470-80.
      View in: PubMed
    44. Wang X, Cederbaum AI. Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and -independent pathways. Free Radic Biol Med. 2007 Apr 1; 42(7):971-84.
      View in: PubMed
    45. Caro AA, Cederbaum AI. Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1. Arch Biochem Biophys. 2007 Jan 15; 457(2):252-63.
      View in: PubMed
    46. Cederbaum AI. Cytochrome P450 2E1-dependent oxidant stress and upregulation of anti-oxidant defense in liver cells. J Gastroenterol Hepatol. 2006 Oct; 21 Suppl 3:S22-5.
      View in: PubMed
    47. Bai J, Cederbaum AI. Cycloheximide protects HepG2 cells from serum withdrawal-induced apoptosis by decreasing p53 and phosphorylated p53 levels. J Pharmacol Exp Ther. 2006 Dec; 319(3):1435-43.
      View in: PubMed
    48. Zhuge J, Cederbaum AI. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1. Free Radic Biol Med. 2006 Oct 1; 41(7):1100-12.
      View in: PubMed
    49. Lu Y, Cederbaum AI. Enhancement by pyrazole of lipopolysaccharide-induced liver injury in mice: role of cytochrome P450 2E1 and 2A5. Hepatology. 2006 Jul; 44(1):263-74.
      View in: PubMed
    50. Wu D, Cederbaum A. Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity. Toxicol Appl Pharmacol. 2006 Oct 15; 216(2):282-92.
      View in: PubMed
    51. Cederbaum AI. CYP2E1--biochemical and toxicological aspects and role in alcohol-induced liver injury. Mt Sinai J Med. 2006 Jul; 73(4):657-72.
      View in: PubMed
    52. Caro AA, Cederbaum AI. Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity. J Pharmacol Exp Ther. 2006 Jul; 318(1):360-72.
      View in: PubMed
    53. Gong P, Cederbaum AI. Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity. J Biol Chem. 2006 May 26; 281(21):14573-9.
      View in: PubMed
    54. Bai J, Cederbaum AI. Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice. Toxicol Sci. 2006 Jun; 91(2):365-71.
      View in: PubMed
    55. Inami K, Nims RW, Srinivasan A, Citro ML, Saavedra JE, Cederbaum AI, Keefer LK. Metabolism of a liver-selective nitric oxide-releasing agent, V-PYRRO/NO, by human microsomal cytochromes P450. Nitric Oxide. 2006 Jun; 14(4):309-15.
      View in: PubMed
    56. Dey A, Cederbaum AI. Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells. J Pharmacol Exp Ther. 2006 Jun; 317(3):1391-9.
      View in: PubMed
    57. Dey A, Kessova IG, Cederbaum AI. Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1. Arch Biochem Biophys. 2006 Mar 15; 447(2):155-66.
      View in: PubMed
    58. Dey A, Cederbaum AI. Alcohol and oxidative liver injury. Hepatology. 2006 Feb; 43(2 Suppl 1):S63-74.
      View in: PubMed
    59. Gong P, Cederbaum AI. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1. Hepatology. 2006 Jan; 43(1):144-53.
      View in: PubMed
    60. Bai J, Cederbaum AI. Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione. J Biol Chem. 2006 Feb 24; 281(8):5128-36.
      View in: PubMed
    61. Wang X, Cederbaum AI. S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice. J Pharmacol Exp Ther. 2006 Apr; 317(1):44-52.
      View in: PubMed
    62. Jimenez-Lopez JM, Cederbaum AI. CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury. Expert Opin Drug Metab Toxicol. 2005 Dec; 1(4):671-85.
      View in: PubMed
    63. Wu D, Cederbaum AI. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells. Am J Physiol Gastrointest Liver Physiol. 2006 Apr; 290(4):G674-84.
      View in: PubMed
    64. Caro AA, Cederbaum AI. Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity. Free Radic Biol Med. 2006 Feb 1; 40(3):364-75.
      View in: PubMed
    65. Lu Y, Cederbaum AI. Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1. Toxicol Sci. 2006 Feb; 89(2):515-23.
      View in: PubMed
    66. Zhuge J, Cederbaum AI. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1. Free Radic Biol Med. 2006 Jan 1; 40(1):63-74.
      View in: PubMed
    67. Wu D, Cederbaum AI. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1. Toxicol Appl Pharmacol. 2005 Sep 1; 207(2 Suppl):70-6.
      View in: PubMed
    68. Lakshman R, Cederbaum AI, Hoek JB, Konishi M, Koop D, Donohu TM. Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol. Alcohol Clin Exp Res. 2005 Sep; 29(9):1726-34.
      View in: PubMed
    69. Wang X, Lu Y, Cederbaum AI. Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice. Hepatology. 2005 Aug; 42(2):400-10.
      View in: PubMed
    70. Kessova IG, Cederbaum AI. The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells. J Pharmacol Exp Ther. 2005 Oct; 315(1):304-12.
      View in: PubMed
    71. Nieto N, Cederbaum AI. S-adenosylmethionine blocks collagen I production by preventing transforming growth factor-beta induction of the COL1A2 promoter. J Biol Chem. 2005 Sep 2; 280(35):30963-74.
      View in: PubMed
    72. Lu Y, Wang X, Cederbaum AI. Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole. Am J Physiol Gastrointest Liver Physiol. 2005 Aug; 289(2):G308-19.
      View in: PubMed
    73. Caro AA, Cederbaum AI. Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine. Biochem Pharmacol. 2005 Apr 1; 69(7):1081-93.
      View in: PubMed
    74. Gong P, Hu B, Cederbaum AI. Diallyl sulfide induces heme oxygenase-1 through MAPK pathway. Arch Biochem Biophys. 2004 Dec 15; 432(2):252-60.
      View in: PubMed
    75. Carmiel-Haggai M, Cederbaum AI, Nieto N. A high-fat diet leads to the progression of non-alcoholic fatty liver disease in obese rats. FASEB J. 2005 Jan; 19(1):136-8.
      View in: PubMed
    76. Jimenez-Lopez JM, Cederbaum AI. Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells. J Pharmacol Exp Ther. 2005 Mar; 312(3):998-1006.
      View in: PubMed
    77. Wu D, Cederbaum A. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity. Mol Pharmacol. 2004 Sep; 66(3):749-60.
      View in: PubMed
    78. Bai J, Cederbaum AI. Adenovirus mediated overexpression of CYP2E1 increases sensitivity of HepG2 cells to acetaminophen induced cytotoxicity. Mol Cell Biochem. 2004 Jul; 262(1-2):165-76.
      View in: PubMed
    79. Caro AA, Cederbaum AI. Antioxidant properties of S-adenosyl-L-methionine in Fe(2+)-initiated oxidations. Free Radic Biol Med. 2004 May 15; 36(10):1303-16.
      View in: PubMed
    80. Pan M, Cederbaum AI, Zhang YL, Ginsberg HN, Williams KJ, Fisher EA. Lipid peroxidation and oxidant stress regulate hepatic apolipoprotein B degradation and VLDL production. J Clin Invest. 2004 May; 113(9):1277-87.
      View in: PubMed
    81. Gong P, Cederbaum AI, Nieto N. Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. Free Radic Biol Med. 2004 Feb 1; 36(3):307-18.
      View in: PubMed
    82. Jimenez-Lopez JM, Cederbaum AI. Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity. Free Radic Biol Med. 2004 Feb 1; 36(3):359-70.
      View in: PubMed
    83. Caro AA, Cederbaum AI. Oxidative stress, toxicology, and pharmacology of CYP2E1. Annu Rev Pharmacol Toxicol. 2004; 44:27-42.
      View in: PubMed
    84. Gong P, Cederbaum AI, Nieto N. The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. Mol Pharmacol. 2004 Jan; 65(1):130-8.
      View in: PubMed
    85. Carmiel-Haggai M, Cederbaum AI, Nieto N. Binge ethanol exposure increases liver injury in obese rats. Gastroenterology. 2003 Dec; 125(6):1818-33.
      View in: PubMed
    86. Holownia A, Cederbaum AI. Threshold for antiproliferative and proapoptotic activity of ttaxol in HepG2 cells expressing human CYP3A4: effect of P-glycoprotein transporters. Pharmacology. 2003 Nov; 69(3):142-9.
      View in: PubMed
    87. Pérez MJ, Cederbaum AI. Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity. Hepatology. 2003 Nov; 38(5):1146-58.
      View in: PubMed
    88. Kessova IG, Ho YS, Thung S, Cederbaum AI. Alcohol-induced liver injury in mice lacking Cu, Zn-superoxide dismutase. Hepatology. 2003 Nov; 38(5):1136-45.
      View in: PubMed
    89. Kessova I, Cederbaum AI. CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury. Curr Mol Med. 2003 Sep; 3(6):509-18.
      View in: PubMed
    90. Ishii H, Adachi M, Fernández-Checa JC, Cederbaum AI, Deaciuc IV, Nanji AA. Role of apoptosis in alcoholic liver injury. Alcohol Clin Exp Res. 2003 Jul; 27(7):1207-12.
      View in: PubMed
    91. Caro AA, Cederbaum AI. Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells. J Biol Chem. 2003 Sep 5; 278(36):33866-77.
      View in: PubMed
    92. Pérez MJ, Cederbaum AI. Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells. Hepatology. 2003 Jun; 37(6):1395-404.
      View in: PubMed
    93. Cederbaum AI. Iron and CYP2E1-dependent oxidative stress and toxicity. Alcohol. 2003 Jun; 30(2):115-20.
      View in: PubMed
    94. Gong P, Cederbaum AI, Nieto N. Increased expression of cytochrome P450 2E1 induces heme oxygenase-1 through ERK MAPK pathway. J Biol Chem. 2003 Aug 8; 278(32):29693-700.
      View in: PubMed
    95. Pérez MJ, Cederbaum AI. Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity. Free Radic Biol Med. 2003 Feb 15; 34(4):443-55.
      View in: PubMed
    96. Nieto N, Cederbaum AI. Increased Sp1-dependent transactivation of the LAMgamma 1 promoter in hepatic stellate cells co-cultured with HepG2 cells overexpressing cytochrome P450 2E1. J Biol Chem. 2003 Apr 25; 278(17):15360-72.
      View in: PubMed
    97. Nieto N, Marí M, Cederbaum AI. Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit. Hepatology. 2003 Jan; 37(1):96-106.
      View in: PubMed
    98. Wu D, Cederbaum AI. Alcohol, oxidative stress, and free radical damage. Alcohol Res Health. 2003; 27(4):277-84.
      View in: PubMed
    99. Caro AA, Cederbaum AI. Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1. Arch Biochem Biophys. 2002 Dec 15; 408(2):162-70.
      View in: PubMed
    100. Bai J, Cederbaum AI. Catalase protects HepG2 cells from apoptosis induced by DNA-damaging agents by accelerating the degradation of p53. J Biol Chem. 2003 Feb 14; 278(7):4660-7.
      View in: PubMed
    101. Wu D, Cederbaum AI. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity. J Biol Chem. 2003 Jan 10; 278(2):1115-24.
      View in: PubMed
    102. Pérez MJ, Cederbaum AI. Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity. Free Radic Biol Med. 2002 Jul 1; 33(1):111-27.
      View in: PubMed
    103. Wu D, Cederbaum AI. Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria. Hepatology. 2002 Jun; 35(6):1420-30.
      View in: PubMed
    104. Marí M, Bai J, Cederbaum AI. Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1. J Pharmacol Exp Ther. 2002 Apr; 301(1):111-8.
      View in: PubMed
    105. Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Mechanisms of hepatotoxicity. Toxicol Sci. 2002 Feb; 65(2):166-76.
      View in: PubMed
    106. Nieto N, Friedman SL, Cederbaum AI. Cytochrome P450 2E1-derived reactive oxygen species mediate paracrine stimulation of collagen I protein synthesis by hepatic stellate cells. J Biol Chem. 2002 Mar 22; 277(12):9853-64.
      View in: PubMed
    107. Nieto N, Friedman SL, Cederbaum AI. Stimulation and proliferation of primary rat hepatic stellate cells by cytochrome P450 2E1-derived reactive oxygen species. Hepatology. 2002 Jan; 35(1):62-73.
      View in: PubMed
    108. Marí M, Bai J, Cederbaum AI. Toxicity by pyruvate in HepG2 cells depleted of glutathione: role of mitochondria. Free Radic Biol Med. 2002 Jan 1; 32(1):73-83.
      View in: PubMed
    109. Cederbaum AI, Wu D, Mari M, Bai J. CYP2E1-dependent toxicity and oxidative stress in HepG2 cells. Free Radic Biol Med. 2001 Dec 15; 31(12):1539-43.
      View in: PubMed
    110. Cederbaum AI. Introduction-serial review: alcohol, oxidative stress and cell injury. Free Radic Biol Med. 2001 Dec 15; 31(12):1524-6.
      View in: PubMed
    111. Caro AA, Cederbaum AI. Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells. J Biol Chem. 2002 Jan 4; 277(1):104-13.
      View in: PubMed
    112. Caro AA, Cederbaum AI. Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1. Mol Pharmacol. 2001 Oct; 60(4):742-52.
      View in: PubMed
    113. Novakov CP, Feierman D, Cederbaum AI, Stoyanovsky DA. An ESR and HPLC-EC assay for the detection of alkyl radicals. Chem Res Toxicol. 2001 Sep; 14(9):1239-46.
      View in: PubMed
    114. Caro AA, Cederbaum AI, Stoyanovsky DA. Oxidation of the ketoxime acetoxime to nitric oxide by oxygen radical-generating systems. Nitric Oxide. 2001 Aug; 5(4):413-24.
      View in: PubMed
    115. Clancy R, Cederbaum AI, Stoyanovsky DA. Preparation and properties of S-nitroso-L-cysteine ethyl ester, an intracellular nitrosating agent. J Med Chem. 2001 Jun 7; 44(12):2035-8.
      View in: PubMed
    116. Casey CA, Nanji A, Cederbaum AI, Adachi M, Takahashi T. Alcoholic liver disease and apoptosis. Alcohol Clin Exp Res. 2001 May; 25(5 Suppl ISBRA):49S-53S.
      View in: PubMed
    117. Bai J, Cederbaum AI. Mitochondrial catalase and oxidative injury. Biol Signals Recept. 2001 May-Aug; 10(3-4):189-99.
      View in: PubMed
    118. Chen J, Clemens DL, Cederbaum AI, Gao B. Ethanol inhibits the JAK-STAT signaling pathway in freshly isolated rat hepatocytes but not in cultured hepatocytes or HepG2 cells: evidence for a lack of involvement of ethanol metabolism. Clin Biochem. 2001 May; 34(3):203-9.
      View in: PubMed
    119. Pérez MJ, Cederbaum AI. Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity. Free Radic Biol Med. 2001 Apr 1; 30(7):734-46.
      View in: PubMed
    120. Wu D, Cederbaum AI. Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1. Alcohol Clin Exp Res. 2001 Apr; 25(4):619-28.
      View in: PubMed
    121. Wu D, Cederbaum AI. Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes. Mol Pharmacol. 2001 Apr; 59(4):795-805.
      View in: PubMed
    122. Marí M, Cederbaum AI. Induction of catalase, alpha, and microsomal glutathione S-transferase in CYP2E1 overexpressing HepG2 cells and protection against short-term oxidative stress. Hepatology. 2001 Mar; 33(3):652-61.
      View in: PubMed
    123. Marí M, Wu D, Nieto N, Cederbaum AI. CYP2E1-dependent toxicity and up-regulation of antioxidant genes. J Biomed Sci. 2001 Jan-Feb; 8(1):52-8.
      View in: PubMed
    124. Bai J, Cederbaum AI. Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against cytochrome P450 2E1-dependent toxicity in HepG2 cells. J Biol Chem. 2001 Feb 9; 276(6):4315-21.
      View in: PubMed
    125. Goasduff T, Cederbaum AI. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90. Arch Biochem Biophys. 2000 Jul 15; 379(2):321-30.
      View in: PubMed
    126. Nieto N, Greenwel P, Friedman SL, Zhang F, Dannenberg AJ, Cederbaum AI. Ethanol and arachidonic acid increase alpha 2(I) collagen expression in rat hepatic stellate cells overexpressing cytochrome P450 2E1. Role of H2O2 and cyclooxygenase-2. J Biol Chem. 2000 Jun 30; 275(26):20136-45.
      View in: PubMed
    127. Bai J, Cederbaum AI. Overexpression of catalase in the mitochondrial or cytosolic compartment increases sensitivity of HepG2 cells to tumor necrosis factor-alpha-induced apoptosis. J Biol Chem. 2000 Jun 23; 275(25):19241-9.
      View in: PubMed
    128. Marí M, Cederbaum AI. CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase. J Biol Chem. 2000 May 19; 275(20):15563-71.
      View in: PubMed
    129. Sakurai K, Stoyanovsky DA, Fujimoto Y, Cederbaum AI. Mitochondrial permeability transition induced by 1-hydroxyethyl radical. Free Radic Biol Med. 2000 Jan 15; 28(2):273-80.
      View in: PubMed
    130. Wu D, Cederbaum AI. Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1. Mol Cell Biochem. 2000 Jan; 204(1-2):157-67.
      View in: PubMed
    131. Puntarulo S, Stoyanovsky DA, Cederbaum AI. Interaction of 1-hydroxyethyl radical with antioxidant enzymes. Arch Biochem Biophys. 1999 Dec 15; 372(2):355-9.
      View in: PubMed
    132. Goasduff T, Cederbaum AI. NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species. Arch Biochem Biophys. 1999 Oct 15; 370(2):258-70.
      View in: PubMed
    133. Nieto N, Friedman SL, Greenwel P, Cederbaum AI. CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells. Hepatology. 1999 Oct; 30(4):987-96.
      View in: PubMed
    134. Bai J, Rodriguez AM, Melendez JA, Cederbaum AI. Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury. J Biol Chem. 1999 Sep 10; 274(37):26217-24.
      View in: PubMed
    135. Stoyanovsky DA, Cederbaum AI. Metabolism of carbon tetrachloride to trichloromethyl radical: An ESR and HPLC-EC study. Chem Res Toxicol. 1999 Aug; 12(8):730-6.
      View in: PubMed
    136. Cederbaum AI. Effects of alcohol on hepatic mitochondrial function and DNA. Gastroenterology. 1999 Jul; 117(1):265-9.
      View in: PubMed
    137. Stoyanovsky DA, Cederbaum AI. Metabolites of acetaminophen trigger Ca2+ release from liver microsomes. Toxicol Lett. 1999 May 20; 106(1):23-9.
      View in: PubMed
    138. Stoyanovsky DA, Melnikov Z, Cederbaum AI. ESR and HPLC-EC analysis of the interaction of hydroxyl radical with DMSO: rapid reduction and quantification of POBN and PBN nitroxides. Anal Chem. 1999 Feb 1; 71(3):715-21.
      View in: PubMed
    139. Wu D, Cederbaum AI. Ethanol-induced apoptosis to stable HepG2 cell lines expressing human cytochrome P-4502E1. Alcohol Clin Exp Res. 1999 Jan; 23(1):67-76.
      View in: PubMed
    140. Sakurai K, Cederbaum AI. Oxidative stress and cytotoxicity induced by ferric-nitrilotriacetate in HepG2 cells that express cytochrome P450 2E1. Mol Pharmacol. 1998 Dec; 54(6):1024-35.
      View in: PubMed
    141. Stoyanovsky DA, Cederbaum AI. ESR and HPLC-EC analysis of ethanol oxidation to 1-hydroxyethyl radical: rapid reduction and quantification of POBN and PBN nitroxides. Free Radic Biol Med. 1998 Sep; 25(4-5):536-45.
      View in: PubMed
    142. Cederbaum AI. Use of transduced cell lines in studies on alcohol metabolism and toxicity. Introduction to the symposium. Alcohol Clin Exp Res. 1998 Jun; 22(4):777.
      View in: PubMed
    143. Chen Q, Galleano M, Cederbaum AI. Cytotoxicity and apoptosis produced by arachidonic acid in HepG2 cells overexpressing human cytochrome P-4502E1. Alcohol Clin Exp Res. 1998 Jun; 22(4):782-4.
      View in: PubMed
    144. Puntarulo S, Cederbaum AI. Production of reactive oxygen species by microsomes enriched in specific human cytochrome P450 enzymes. Free Radic Biol Med. 1998 May; 24(7-8):1324-30.
      View in: PubMed
    145. Chen Q, Cederbaum AI. Cytotoxicity and apoptosis produced by cytochrome P450 2E1 in Hep G2 cells. Mol Pharmacol. 1998 Apr; 53(4):638-48.
      View in: PubMed
    146. Stoyanovsky DA, Cederbaum AI. Redox-cycling of iron ions triggers calcium release from liver microsomes. Free Radic Biol Med. 1998 Mar 15; 24(5):745-53.
      View in: PubMed
    147. Stoyanovsky DA, Wu D, Cederbaum AI. Interaction of 1-hydroxyethyl radical with glutathione, ascorbic acid and alpha-tocopherol. Free Radic Biol Med. 1998 Jan 1; 24(1):132-8.
      View in: PubMed
    148. Cederbaum AI. Ethanol-related cytotoxicity catalyzed by CYP2E1-dependent generation of reactive oxygen intermediates in transduced HepG2 cells. Biofactors. 1998; 8(1-2):93-6.
      View in: PubMed
    149. Gergel' D, Cederbaum AI. Interaction of nitric oxide with 2-thio-5-nitrobenzoic acid: implications for the determination of free sulfhydryl groups by Ellman's reagent. Arch Biochem Biophys. 1997 Nov 15; 347(2):282-8.
      View in: PubMed
    150. Chen Q, Cederbaum AI. Menadione cytotoxicity to Hep G2 cells and protection by activation of nuclear factor-kappaB. Mol Pharmacol. 1997 Oct; 52(4):648-57.
      View in: PubMed
    151. Wu D, Ramin SA, Cederbaum AI. Effect of pyridine on the expression of cytochrome P450 isozymes in primary rat hepatocyte culture. Mol Cell Biochem. 1997 Aug; 173(1-2):103-11.
      View in: PubMed
    152. Chen Q, Galleano M, Cederbaum AI. Cytotoxicity and apoptosis produced by arachidonic acid in Hep G2 cells overexpressing human cytochrome P4502E1. J Biol Chem. 1997 Jun 6; 272(23):14532-41.
      View in: PubMed
    153. Yang MX, Cederbaum AI. Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1. Arch Biochem Biophys. 1997 May 1; 341(1):25-33.
      View in: PubMed
    154. Yang MX, Cederbaum AI. Glycerol increases content and activity of human cytochrome P-4502E1 in a transduced HepG2 cell line by protein stabilization. Alcohol Clin Exp Res. 1997 Apr; 21(2):340-7.
      View in: PubMed
    155. Puntarulo S, Cederbaum AI. Inhibition of ferritin-stimulated microsomal production of reactive oxygen intermediates by nitric oxide. Arch Biochem Biophys. 1997 Apr 1; 340(1):19-26.
      View in: PubMed
    156. Gergel D, Misík V, Riesz P, Cederbaum AI. Inhibition of rat and human cytochrome P4502E1 catalytic activity and reactive oxygen radical formation by nitric oxide. Arch Biochem Biophys. 1997 Jan 15; 337(2):239-50.
      View in: PubMed
    157. Rao DN, Cederbaum AI. A comparative study of the redox-cycling of a quinone (rifamycin S) and a quinonimine (rifabutin) antibiotic by rat liver microsomes. Free Radic Biol Med. 1997; 22(3):439-46.
      View in: PubMed
    158. Gergel D, Cederbaum AI. Inhibition of the catalytic activity of alcohol dehydrogenase by nitric oxide is associated with S nitrosylation and the release of zinc. Biochemistry. 1996 Dec 17; 35(50):16186-94.
      View in: PubMed
    159. Stoyanovsky DA, Cederbaum AI. Thiol oxidation and cytochrome P450-dependent metabolism of CCl4 triggers Ca2+ release from liver microsomes. Biochemistry. 1996 Dec 10; 35(49):15839-45.
      View in: PubMed
    160. Wu D, Cederbaum AI. Ethanol cytotoxicity to a transfected HepG2 cell line expressing human cytochrome P4502E1. J Biol Chem. 1996 Sep 27; 271(39):23914-9.
      View in: PubMed
    161. Yang MX, Cederbaum AI. Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells. Biochem Biophys Res Commun. 1996 Sep 24; 226(3):711-6.
      View in: PubMed
    162. Kukielka E, Cederbaum AI. Ferritin stimulation of lipid peroxidation by microsomes after chronic ethanol treatment: role of cytochrome P4502E1. Arch Biochem Biophys. 1996 Aug 1; 332(1):121-7.
      View in: PubMed
    163. Yang MX, Cederbaum AI. Interaction of ferric complexes with NADH-cytochrome b5 reductase and cytochrome b5: lipid peroxidation, H2O2 generation, and ferric reduction. Arch Biochem Biophys. 1996 Jul 1; 331(1):69-78.
      View in: PubMed
    164. Wu D, Cederbaum AI. Expression of cytochrome P4502E1 in rat fetal hepatocyte culture. Mol Pharmacol. 1996 May; 49(5):802-7.
      View in: PubMed
    165. Rao DN, Yang MX, Lasker JM, Cederbaum AI. 1-Hydroxyethyl radical formation during NADPH- and NADH-dependent oxidation of ethanol by human liver microsomes. Mol Pharmacol. 1996 May; 49(5):814-21.
      View in: PubMed
    166. Ramakrishna Rao DN, Cederbaum AI. Generation of reactive oxygen species by the redox cycling of nitroprusside. Biochim Biophys Acta. 1996 Mar 15; 1289(2):195-202.
      View in: PubMed
    167. Puntarulo S, Cederbaum AI. Role of cytochrome P-450 in the stimulation of microsomal production of reactive oxygen species by ferritin. Biochim Biophys Acta. 1996 Mar 15; 1289(2):238-46.
      View in: PubMed
    168. Yang MX, Cederbaum AI. Role of cytochrome b5 in NADH-dependent microsomal reduction of ferric complexes, lipid peroxidation, and hydrogen peroxide generation. Arch Biochem Biophys. 1995 Dec 20; 324(2):282-92.
      View in: PubMed
    169. Dai Y, Cederbaum AI. Inactivation and degradation of human cytochrome P4502E1 by CCl4 in a transfected HepG2 cell line. J Pharmacol Exp Ther. 1995 Dec; 275(3):1614-22.
      View in: PubMed
    170. Kukielka E, Cederbaum AI. Increased production of hydroxyl radical by pericentral microsomes compared to periportal microsomes after pyrazole induction of cytochrome P4502E1. Biochem Biophys Res Commun. 1995 Oct 13; 215(2):698-705.
      View in: PubMed
    171. Gergel D, Misík V, Ondrias K, Cederbaum AI. Increased cytotoxicity of 3-morpholinosydnonimine to HepG2 cells in the presence of superoxide dismutase. Role of hydrogen peroxide and iron. J Biol Chem. 1995 Sep 8; 270(36):20922-9.
      View in: PubMed
    172. Rao DN, Cederbaum AI. Production of nitric oxide and other iron-containing metabolites during the reductive metabolism of nitroprusside by microsomes and by thiols. Arch Biochem Biophys. 1995 Aug 20; 321(2):363-71.
      View in: PubMed
    173. Dai Y, Cederbaum AI. Cytotoxicity of acetaminophen in human cytochrome P4502E1-transfected HepG2 cells. J Pharmacol Exp Ther. 1995 Jun; 273(3):1497-505.
      View in: PubMed
    174. Kukielka E, Cederbaum AI. Increased oxidation of ethylene glycol to formaldehyde by microsomes after ethanol treatment: role of oxygen radicals and cytochrome P450. Toxicol Lett. 1995 Jun; 78(1):9-15.
      View in: PubMed
    175. Kukielka E, Cederbaum AI. Stimulation of NADH-dependent microsomal DNA strand cleavage by rifamycin SV. Biochem J. 1995 Apr 15; 307 ( Pt 2):361-7.
      View in: PubMed
    176. Kringstein P, Cederbaum AI. Boldine prevents human liver microsomal lipid peroxidation and inactivation of cytochrome P4502E1. Free Radic Biol Med. 1995 Mar; 18(3):559-63.
      View in: PubMed
    177. Yang MX, Cederbaum AI. Fractionation of liver microsomes with polyethylene glycol and purification of NADH-cytochrome b5 oxidoreductase and cytochrome b5. Arch Biochem Biophys. 1994 Dec; 315(2):438-44.
      View in: PubMed
    178. Kukielka E, Cederbaum AI. DNA strand cleavage as a sensitive assay for the production of hydroxyl radicals by microsomes: role of cytochrome P4502E1 in the increased activity after ethanol treatment. Biochem J. 1994 Sep 15; 302 ( Pt 3):773-9.
      View in: PubMed
    179. Carroccio A, Wu D, Cederbaum AI. Ethanol increases content and activity of human cytochrome P4502E1 in a transduced HepG2 cell line. Biochem Biophys Res Commun. 1994 Aug 30; 203(1):727-33.
      View in: PubMed
    180. Rashba-Step J, Step E, Turro NJ, Cederbaum AI. Oxidation of glycerol to formaldehyde by microsomes: are glycerol radicals produced in the reaction pathway? Biochemistry. 1994 Aug 16; 33(32):9504-10.
      View in: PubMed
    181. Wu D, Cederbaum AI. Characterization of pyrazole and 4-methylpyrazole induction of cytochrome P4502E1 in rat kidney. J Pharmacol Exp Ther. 1994 Jul; 270(1):407-13.
      View in: PubMed
    182. Puntarulo S, Cederbaum AI. Ferritin-dependent inactivation of microsomal glucose-6-phosphatase. Biochim Biophys Acta. 1994 May 25; 1200(1):41-7.
      View in: PubMed
    183. Kukielka E, Dicker E, Cederbaum AI. Increased production of reactive oxygen species by rat liver mitochondria after chronic ethanol treatment. Arch Biochem Biophys. 1994 Mar; 309(2):377-86.
      View in: PubMed
    184. Rashba-Step J, Cederbaum AI. Generation of reactive oxygen intermediates by human liver microsomes in the presence of NADPH or NADH. Mol Pharmacol. 1994 Jan; 45(1):150-7.
      View in: PubMed
    185. Kukielka E, Cederbaum AI. Ferritin stimulation of hydroxyl radical production by rat liver nuclei. Arch Biochem Biophys. 1994 Jan; 308(1):70-7.
      View in: PubMed
    186. Clejan LA, Cederbaum AI. Stimulation by paraquat of microsomal and cytochrome P-450-dependent oxidation of glycerol to formaldehyde. Biochem J. 1993 Nov 1; 295 ( Pt 3):781-6.
      View in: PubMed
    187. Wu D, Cederbaum AI. Ethanol consumption by the nursing mother induces cytochrome P-4502E1 in neonatal rat liver. J Pharmacol Exp Ther. 1993 Oct; 267(1):560-6.
      View in: PubMed
    188. Dicker E, Cederbaum AI. Requirement for iron for the production of hydroxyl radicals by rat liver quinone reductase. J Pharmacol Exp Ther. 1993 Sep; 266(3):1282-90.
      View in: PubMed
    189. Dai Y, Rashba-Step J, Cederbaum AI. Stable expression of human cytochrome P4502E1 in HepG2 cells: characterization of catalytic activities and production of reactive oxygen intermediates. Biochemistry. 1993 Jul 13; 32(27):6928-37.
      View in: PubMed
    190. Puntarulo S, Cederbaum AI. Stimulation of microsomal chemiluminescence by ferritin. Biochim Biophys Acta. 1993 May 7; 1157(1):1-8.
      View in: PubMed
    191. Wu D, Cederbaum AI. Combined effects of streptozotocin-induced diabetes plus 4-methylpyrazole treatment on rat liver cytochrome P4502E1. Arch Biochem Biophys. 1993 Apr; 302(1):175-82.
      View in: PubMed
    192. Wu D, Cederbaum AI. Induction of liver cytochrome P4502E1 by pyrazole and 4-methylpyrazole in neonatal rats. J Pharmacol Exp Ther. 1993 Mar; 264(3):1468-73.
      View in: PubMed
    193. Rashba-Step J, Turro NJ, Cederbaum AI. ESR studies on the production of reactive oxygen intermediates by rat liver microsomes in the presence of NADPH or NADH. Arch Biochem Biophys. 1993 Jan; 300(1):391-400.
      View in: PubMed
    194. Rashba-Step J, Turro NJ, Cederbaum AI. Increased NADPH- and NADH-dependent production of superoxide and hydroxyl radical by microsomes after chronic ethanol treatment. Arch Biochem Biophys. 1993 Jan; 300(1):401-8.
      View in: PubMed
    195. Winters DK, Cederbaum AI. Expression of a catalytically active human cytochrome P-4502E1 in Escherichia coli. Biochim Biophys Acta. 1992 Dec 8; 1156(1):43-9.
      View in: PubMed
    196. Cederbaum AI, Kukielka E, Speisky H. Inhibition of rat liver microsomal lipid peroxidation by boldine. Biochem Pharmacol. 1992 Nov 3; 44(9):1765-72.
      View in: PubMed
    197. Kukielka E, Cederbaum AI. Stimulation of microsomal production of reactive oxygen intermediates by rifamycin SV: effect of ferric complexes and comparisons between NADPH and NADH. Arch Biochem Biophys. 1992 Nov 1; 298(2):602-11.
      View in: PubMed
    198. Clejan LA, Cederbaum AI. Structural determinants for alcohol substrates to be oxidized to formaldehyde by rat liver microsomes. Arch Biochem Biophys. 1992 Oct; 298(1):105-13.
      View in: PubMed
    199. Winters DK, Cederbaum AI. Time course characterization of the induction of cytochrome P-450 2E1 by pyrazole and 4-methylpyrazole. Biochim Biophys Acta. 1992 Jul 21; 1117(1):15-24.
      View in: PubMed
    200. Kukielka E, Cederbaum AI. The effect of chronic ethanol consumption on NADH- and NADPH-dependent generation of reactive oxygen intermediates by isolated rat liver nuclei. Alcohol Alcohol. 1992 May; 27(3):233-9.
      View in: PubMed
    201. Puntarulo S, Cederbaum AI. Effect of phenobarbital and 3-methylcholanthrene treatment on NADPH- and NADH-dependent production of reactive oxygen intermediates by rat liver nuclei. Biochim Biophys Acta. 1992 Mar 5; 1116(1):17-23.
      View in: PubMed
    202. Dicker E, Cederbaum AI. Increased NADH-dependent production of reactive oxygen intermediates by microsomes after chronic ethanol consumption: comparisons with NADPH. Arch Biochem Biophys. 1992 Mar; 293(2):274-80.
      View in: PubMed
    203. Wu D, Cederbaum AI. Presence of functionally active cytochrome P-450IIE1 in the plasma membrane of rat hepatocytes. Hepatology. 1992 Mar; 15(3):515-24.
      View in: PubMed
    204. Clejan LA, Cederbaum AI. Role of cytochrome P450 in the oxidation of glycerol by reconstituted systems and microsomes. FASEB J. 1992 Jan 6; 6(2):765-70.
      View in: PubMed
    205. Winters DK, Cederbaum AI. The content and activity of cytochrome P450 2E1 in liver microsomes from alcohol-preferring and non-preferring rats. Alcohol Alcohol. 1992 Jan; 27(1):63-70.
      View in: PubMed
    206. Dicker E, Cederbaum AI. Increased oxidation of dimethylnitrosamine in pericentral microsomes after pyrazole induction of cytochrome P-4502E1. Alcohol Clin Exp Res. 1991 Dec; 15(6):1072-6.
      View in: PubMed
    207. Kukielka E, Cederbaum AI. Oxidation of ethylene glycol to formaldehyde by rat liver microsomes. Role of cytochrome P-450 and reactive oxygen species. Drug Metab Dispos. 1991 Nov-Dec; 19(6):1108-15.
      View in: PubMed
    208. Dicker E, Cederbaum AI. NADH-dependent generation of reactive oxygen species by microsomes in the presence of iron and redox cycling agents. Biochem Pharmacol. 1991 Jul 15; 42(3):529-35.
      View in: PubMed
    209. Olin PS, Cederbaum A, Donahue JL. Effects of lubrication on the retention of tapered and parallel cast post and cores. J Prosthet Dent. 1991 Jul; 66(1):45-9.
      View in: PubMed
    210. Puntarulo S, Cederbaum AI. Inhibition of the oxidation of hydroxyl radical scavenging agents after alkaline phosphatase treatment of rat liver microsomes. Biochim Biophys Acta. 1991 May 24; 1074(1):12-8.
      View in: PubMed
    211. Dicker E, McHugh T, Cederbaum AI. Increased catalytic activity of cytochrome P-450IIE1 in pericentral hepatocytes compared to periportal hepatocytes isolated from pyrazole-treated rats. Biochim Biophys Acta. 1991 Mar 4; 1073(2):316-23.
      View in: PubMed
    212. Clejan LA, Cederbaum AI. Role of iron, hydrogen peroxide and reactive oxygen species in microsomal oxidation of glycerol to formaldehyde. Arch Biochem Biophys. 1991 Feb 15; 285(1):83-9.
      View in: PubMed
    213. Cederbaum AI. Microsomal generation of reactive oxygen species and their possible role in alcohol hepatotoxicity. Alcohol Alcohol Suppl. 1991; 1:291-6.
      View in: PubMed
    214. Kukielka E, Cederbaum AI. NADPH- and NADH-dependent oxygen radical generation by rat liver nuclei in the presence of redox cycling agents and iron. Arch Biochem Biophys. 1990 Dec; 283(2):326-33.
      View in: PubMed
    215. Wu DF, Clejan L, Potter B, Cederbaum AI. Rapid decrease of cytochrome P-450IIE1 in primary hepatocyte culture and its maintenance by added 4-methylpyrazole. Hepatology. 1990 Dec; 12(6):1379-89.
      View in: PubMed
    216. Dicker E, McHugh T, Cederbaum AI. Increased oxidation of p-nitrophenol and aniline by intact hepatocytes isolated from pyrazole-treated rats. Biochim Biophys Acta. 1990 Sep 14; 1035(3):249-56.
      View in: PubMed
    217. Clejan LA, Cederbaum AI. Comparison of the interaction of pyrazole and its metabolite 4-hydroxypyrazole with rat liver microsomes. Drug Metab Dispos. 1990 Jul-Aug; 18(4):393-7.
      View in: PubMed
    218. Clejan LA, Cederbaum AI. Oxidation of pyrazole by reconstituted systems containing cytochrome P-450 IIE1. Biochim Biophys Acta. 1990 May 16; 1034(2):233-7.
      View in: PubMed
    219. Dicker E, Cederbaum AI. Generation of reactive oxygen species and reduction of ferric chelates by microsomes in the presence of a reconstituted system containing ethanol, NAD+ and alcohol dehydrogenase. Alcohol Clin Exp Res. 1990 Apr; 14(2):238-44.
      View in: PubMed
    220. Winters DK, Cederbaum AI. Oxidation of glycerol to formaldehyde by rat liver microsomes. Effects of cytochrome P-450 inducing agents. Biochem Pharmacol. 1990 Feb 15; 39(4):697-705.
      View in: PubMed
    221. Kukielka E, Cederbaum AI. NADH-dependent microsomal interaction with ferric complexes and production of reactive oxygen intermediates. Arch Biochem Biophys. 1989 Dec; 275(2):540-50.
      View in: PubMed
    222. Feierman DE, Cederbaum AI. Role of cytochrome P-450 IIE1 and catalase in the oxidation of acetonitrile to cyanide. Chem Res Toxicol. 1989 Nov-Dec; 2(6):359-66.
      View in: PubMed
    223. Clejan LA, Koop DR, Cederbaum AI. Sensitivity of the rat liver microsomal oxidation of pyrazole to antibody raised against the ethanol-inducible rabbit liver cytochrome P-450 isozyme. Drug Metab Dispos. 1989 Nov-Dec; 17(6):694-8.
      View in: PubMed
    224. Puntarulo S, Cederbaum AI. Interactions between paraquat and ferric complexes in the microsomal generation of oxygen radicals. Biochem Pharmacol. 1989 Sep 1; 38(17):2911-8.
      View in: PubMed
    225. Kukielka E, Puntarulo S, Cederbaum AI. Interaction of ferric complexes with rat liver nuclei to catalyze NADH-and NADPH-Dependent production of oxygen radicals. Arch Biochem Biophys. 1989 Sep; 273(2):319-30.
      View in: PubMed
    226. Clejan L, Cederbaum AI. Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals. Biochem Pharmacol. 1989 Jun 1; 38(11):1779-86.
      View in: PubMed
    227. Puntarulo S, Cederbaum AI. Temperature dependence of the microsomal oxidation of ethanol by cytochrome P450 and hydroxyl radical-dependent reactions. Arch Biochem Biophys. 1989 Mar; 269(2):569-75.
      View in: PubMed
    228. Puntarulo S, Cederbaum AI. Chemiluminescence from acetaldehyde oxidation by xanthine oxidase involves generation of and interactions with hydroxyl radicals. Alcohol Clin Exp Res. 1989 Feb; 13(1):84-90.
      View in: PubMed
    229. Cederbaum AI. Oxygen radical generation by microsomes: role of iron and implications for alcohol metabolism and toxicity. Free Radic Biol Med. 1989; 7(5):559-67.
      View in: PubMed
    230. Cederbaum AI. Role of lipid peroxidation and oxidative stress in alcohol toxicity. Free Radic Biol Med. 1989; 7(5):537-9.
      View in: PubMed
    231. Puntarulo S, Turrens JF, Cederbaum AI. Oxygen-concentration dependence of microsomal chemiluminescence. Free Radic Biol Med. 1989; 7(3):269-73.
      View in: PubMed
    232. Puntarulo S, Cederbaum AI. Increased NADPH-dependent chemiluminescence by microsomes after chronic ethanol consumption. Arch Biochem Biophys. 1988 Nov 1; 266(2):435-45.
      View in: PubMed
    233. Dicker E, Cederbaum AI. Increased oxygen radical-dependent inactivation of metabolic enzymes by liver microsomes after chronic ethanol consumption. FASEB J. 1988 Oct; 2(13):2901-6.
      View in: PubMed
    234. Puntarulo S, Cederbaum AI. Comparison of the ability of ferric complexes to catalyze microsomal chemiluminescence, lipid peroxidation, and hydroxyl radical generation. Arch Biochem Biophys. 1988 Aug 1; 264(2):482-91.
      View in: PubMed
    235. Winters DK, Clejan LA, Cederbaum AI. Oxidation of glycerol to formaldehyde by rat liver microsomes. Biochem Biophys Res Commun. 1988 Jun 16; 153(2):612-7.
      View in: PubMed
    236. Puntarulo S, Cederbaum AI. Effect of oxygen concentration on microsomal oxidation of ethanol and generation of oxygen radicals. Biochem J. 1988 May 1; 251(3):787-94.
      View in: PubMed
    237. Puntarulo S, Cederbaum AI. Oxidation of pyrazole to 4-hydroxypyrazole by intact rat hepatocytes. Biochem Pharmacol. 1988 Apr 15; 37(8):1555-61.
      View in: PubMed
    238. Rothman AL, Cheeseman SH, Lehrman SN, Cederbaum A, Glew RH. Herpes simplex encephalitis in a patient with lymphoma. Relapse following acyclovir therapy. JAMA. 1988 Feb 19; 259(7):1056-7.
      View in: PubMed
    239. Palakodety RB, Clejan LA, Krikun G, Feierman DE, Cederbaum AI. Characterization and identification of a pyrazole-inducible form of cytochrome P-450. J Biol Chem. 1988 Jan 15; 263(2):878-84.
      View in: PubMed
    240. Puntarulo S, Cederbaum AI. Increased microsomal interaction with iron and oxygen radical generation after chronic acetone treatment. Biochim Biophys Acta. 1988 Jan 12; 964(1):46-52.
      View in: PubMed
    241. Griffin TW, Hunter RA, Cederbaum AI, Tak WK, Ward AD, Schwartz JH, Halpin TF, Strauss GM, Meyer RN, Liepman MK, et al. Treatment of advanced ovarian cancer with sequential combination chemotherapy. Cancer. 1987 Nov 1; 60(9):2150-5.
      View in: PubMed
    242. Puntarulo S, Cederbaum AI. Chemiluminescence studies on the generation of oxygen radicals from the interaction of NADPH-cytochrome P-450 reductase with iron. Arch Biochem Biophys. 1987 Nov 1; 258(2):510-8.
      View in: PubMed
    243. Feierman DE, Cederbaum AI. Increased sensitivity of the microsomal oxidation of ethanol to inhibition by pyrazole and 4-methylpyrazole after chronic ethanol treatment. Biochem Pharmacol. 1987 Oct 1; 36(19):3277-83.
      View in: PubMed
    244. Feierman DE, Cederbaum AI. Oxidation of the alcohol dehydrogenase inhibitor pyrazole to 4-hydroxypyrazole by microsomes. Effect of cytochrome P-450 inducing agents. Drug Metab Dispos. 1987 Sep-Oct; 15(5):634-9.
      View in: PubMed
    245. Puntarulo S, Cederbaum AI. Production of 4-hydroxypyrazole from the interaction of the alcohol dehydrogenase inhibitor pyrazole with hydroxyl radical. Arch Biochem Biophys. 1987 Jun; 255(2):217-25.
      View in: PubMed
    246. Dicker E, Cederbaum AI. Hydroxyl radical generation by microsomes after chronic ethanol consumption. Alcohol Clin Exp Res. 1987 Jun; 11(3):309-14.
      View in: PubMed
    247. Cederbaum AI. Microsomal generation of hydroxyl radicals: its role in microsomal ethanol oxidizing system (MEOS) activity and requirement for iron. Ann N Y Acad Sci. 1987; 492:35-49.
      View in: PubMed
    248. Dicker E, Cederbaum AI. Inhibition of the low-Km mitochondrial aldehyde dehydrogenase by diethyl maleate and phorone in vivo and in vitro. Implications for formaldehyde metabolism. Biochem J. 1986 Dec 15; 240(3):821-7.
      View in: PubMed
    249. Krikun G, Cederbaum AI. Effect of chronic ethanol consumption on microsomal lipid peroxidation. Role of iron and comparison between controls. FEBS Lett. 1986 Nov 24; 208(2):292-6.
      View in: PubMed
    250. Winston GW, Cederbaum AI. Differential effects of the cytochrome P-450/reductase ratio on the oxidation of ethanol and the hydroxyl radical scavenging agent 2-keto-4-thiomethylbutyric acid (KMBA). Biochem Pharmacol. 1986 Nov 15; 35(22):4053-8.
      View in: PubMed
    251. Feierman DE, Cederbaum AI. Inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole in vitro. Increased effectiveness after induction by pyrazole and 4-methylpyrazole. Biochem J. 1986 Nov 1; 239(3):671-7.
      View in: PubMed
    252. Beloqui O, Cederbaum AI. Prevention of microsomal production of hydroxyl radicals, but not lipid peroxidation, by the glutathione-glutathione peroxidase system. Biochem Pharmacol. 1986 Aug 15; 35(16):2663-9.
      View in: PubMed
    253. Dicker E, Cederbaum AI. Inhibition of CO2 production from aminopyrine or methanol by cyanamide or crotonaldehyde and the role of mitochondrial aldehyde dehydrogenase in formaldehyde oxidation. Biochim Biophys Acta. 1986 Aug 6; 883(1):91-7.
      View in: PubMed
    254. Krikun G, Feierman DE, Cederbaum AI. Rat liver microsomal induction of the oxidation of drugs and alcohols, and sodium dodecyl sulfate-gel profiles after in vivo treatment with pyrazole or 4-methylpyrazole. J Pharmacol Exp Ther. 1986 Jun; 237(3):1012-9.
      View in: PubMed
    255. Winston GW, Eibschutz OM, Strekas T, Cederbaum AI. Complex-formation and reduction of ferric iron by 2-oxo-4-thiomethylbutyric acid, and the production of hydroxyl radicals. Biochem J. 1986 Apr 15; 235(2):521-9.
      View in: PubMed
    256. Cederbaum AI, Dicker E. Inhibition of the peroxidatic activity of catalase towards alcohols by the aldehyde dehydrogenase inhibitor cyanamide. Toxicol Lett. 1985 Dec; 29(2-3):107-14.
      View in: PubMed
    257. Dicker E, Cederbaum AI. Inhibition of mitochondrial aldehyde dehydrogenase and acetaldehyde oxidation by the glutathione-depleting agents diethylmaleate and phorone. Biochim Biophys Acta. 1985 Nov 22; 843(1-2):107-13.
      View in: PubMed
    258. Beloqui O, Cederbaum AI. Microsomal interactions between iron, paraquat, and menadione: effect on hydroxyl radical production and alcohol oxidation. Arch Biochem Biophys. 1985 Oct; 242(1):187-96.
      View in: PubMed
    259. Feierman DE, Cederbaum AI. Interaction of pyrazole and 4-methylpyrazole with hepatic microsomes: effect on cytochrome P-450 content, microsomal oxidation of alcohols, and binding spectra. Alcohol Clin Exp Res. 1985 Sep-Oct; 9(5):421-8.
      View in: PubMed
    260. Krikun G, Cederbaum AI. Evaluation of microsomal pathways of oxidation of alcohols and hydroxyl radical scavenging agents with carbon monoxide and cobalt protoporphyrin IX. Biochem Pharmacol. 1985 Aug 15; 34(16):2929-35.
      View in: PubMed
    261. Feierman DE, Winston GW, Cederbaum AI. Ethanol oxidation by hydroxyl radicals: role of iron chelates, superoxide, and hydrogen peroxide. Alcohol Clin Exp Res. 1985 Mar-Apr; 9(2):95-102.
      View in: PubMed
    262. Feierman DE, Cederbaum AI. Increased content of cytochrome P-450 and 4-methylpyrazole binding spectrum after 4-methylpyrazole treatment. Biochem Biophys Res Commun. 1985 Feb 15; 126(3):1076-81.
      View in: PubMed
    263. Feierman DE, Cederbaum AI. Ethylene production from alpha-keto-4-thiomethylbutyric acid by isolated rat liver cells, suspension medium, and perfusates in the absence and presence of iron. J Free Radic Biol Med. 1985; 1(2):155-62.
      View in: PubMed
    264. Brettler DB, Forsberg AD, O'Connell FD, Cederbaum AI, Chaitman AK, Levine PH. A long-term study of hemophilic arthropathy of the knee joint on a program of Factor VIII replacement given at time of each hemarthrosis. Am J Hematol. 1985 Jan; 18(1):13-8.
      View in: PubMed
    265. Krikun G, Cederbaum AI. Stereochemical studies on the cytochrome P-450 and hydroxyl radical dependent pathways of 2-butanol oxidation by microsomes from chow-fed, phenobarbital-treated, and ethanol-treated rats. Biochemistry. 1984 Nov 6; 23(23):5489-94.
      View in: PubMed
    266. Krikun G, Lieber CS, Cederbaum AI. Increased microsomal oxidation of ethanol by cytochrome P-450 and hydroxyl radical-dependent pathways after chronic ethanol consumption. Biochem Pharmacol. 1984 Oct 15; 33(20):3306-9.
      View in: PubMed
    267. Dicker E, Cederbaum AI. Inhibition of the oxidation of acetaldehyde and formaldehyde by hepatocytes and mitochondria by crotonaldehyde. Arch Biochem Biophys. 1984 Oct; 234(1):187-96.
      View in: PubMed
    268. Krikun G, Cederbaum AI. Increased microsomal oxidation of alcohols after pyrazole treatment and its similarities to the induction by ethanol consumption. Biochim Biophys Acta. 1984 Sep 7; 801(1):131-7.
      View in: PubMed
    269. Winston GW, Feierman DE, Cederbaum AI. The role of iron chelates in hydroxyl radical production by rat liver microsomes, NADPH-cytochrome P-450 reductase and xanthine oxidase. Arch Biochem Biophys. 1984 Jul; 232(1):378-90.
      View in: PubMed
    270. Dicker E, Cederbaum AI. Effect of acetaldehyde and cyanamide on the metabolism of formaldehyde by hepatocytes, mitochondria, and soluble supernatant from rat liver. Arch Biochem Biophys. 1984 Jul; 232(1):179-88.
      View in: PubMed
    271. Cederbaum AI, Cohen G. Microsomal oxidant radical production and ethanol oxidation. Methods Enzymol. 1984; 105:516-22.
      View in: PubMed
    272. Cederbaum AI, Qureshi A, Cohen G. Production of formaldehyde and acetone by hydroxyl-radical generating systems during the metabolism of tertiary butyl alcohol. Biochem Pharmacol. 1983 Dec 1; 32(23):3517-24.
      View in: PubMed
    273. Dicker E, Cederbaum AI. Effect of ethanol and metabolic substrates on the oxidation of aminopyrine, formaldehyde and formate by isolated hepatocytes. J Pharmacol Exp Ther. 1983 Dec; 227(3):687-93.
      View in: PubMed
    274. Winston GW, Harvey W, Berl L, Cederbaum AI. The generation of hydroxyl and alkoxyl radicals from the interaction of ferrous bipyridyl with peroxides. Biochem J. 1983 Nov 15; 216(2):415-21.
      View in: PubMed
    275. Cederbaum AI. Organic hydroperoxide-dependent oxidation of ethanol by microsomes: lack of a role for free hydroxyl radicals. Arch Biochem Biophys. 1983 Nov; 227(1):329-38.
      View in: PubMed
    276. Feierman DE, Cederbaum AI. The effect of EDTA and iron on the oxidation of hydroxyl radical scavenging agents and ethanol by rat liver microsomes. Biochem Biophys Res Commun. 1983 Oct 31; 116(2):765-70.
      View in: PubMed
    277. Klein SM, Cohen G, Lieber CS, Cederbaum AI. Increased microsomal oxidation of hydroxyl radical scavenging agents and ethanol after chronic consumption of ethanol. Arch Biochem Biophys. 1983 Jun; 223(2):425-32.
      View in: PubMed
    278. Winston GW, Cederbaum AI. NADPH-dependent production of oxy radicals by purified components of the rat liver mixed function oxidase system. II. Role in microsomal oxidation of ethanol. J Biol Chem. 1983 Feb 10; 258(3):1514-9.
      View in: PubMed
    279. Winston GW, Cederbaum AI. NADPH-dependent production of oxy radicals by purified components of the rat liver mixed function oxidase system. I. Oxidation of hydroxyl radical scavenging agents. J Biol Chem. 1983 Feb 10; 258(3):1508-13.
      View in: PubMed
    280. Cederbaum AI, Dicker E. Inhibition of microsomal oxidation of alcohols and of hydroxyl-radical-scavenging agents by the iron-chelating agent desferrioxamine. Biochem J. 1983 Jan 15; 210(1):107-13.
      View in: PubMed
    281. Winston GW, Cederbaum AI. Evidence for two ethanol oxidizing pathways in reconstituted mixed-function oxidase systems. Pharmacol Biochem Behav. 1983; 18 Suppl 1:189-94.
      View in: PubMed
    282. Dicker E, Cederbaum A. Evaluation of a role of acetaldehyde in the mechanism of inhibition of p-nitroanisole O-demethylation in isolated hepatocytes by ethanol. Arch Biochem Biophys. 1982 Sep; 217(2):441-51.
      View in: PubMed
    283. Winston GW, Cederbaum AI. Oxidative decarboxylation of benzoate to carbon dioxide by rat liver microsomes: a probe for oxygen radical production during microsomal electron transfer. Biochemistry. 1982 Aug 31; 21(18):4265-70.
      View in: PubMed
    284. Cederbaum AI, Berl L. Pyrazole and 4-methylpyrazole inhibit oxidation of ethanol and dimethyl sulfoxide by hydroxyl radicals generated from ascorbate, xanthine oxidase, and rat liver microsomes. Arch Biochem Biophys. 1982 Jul; 216(2):530-43.
      View in: PubMed
    285. Winston GW, Cederbaum AI. A correlation between hydroxyl radical generation and ethanol oxidation by liver, lung and kidney microsomes. Biochem Pharmacol. 1982 Jun 1; 31(11):2031-7.
      View in: PubMed
    286. Cederbaum AI, Blatt PM, Levine PH. Abnormal serum transaminase levels in patients with hemophilia A. Arch Intern Med. 1982 Mar; 142(3):481-4.
      View in: PubMed
    287. Cederbaum AI, Qureshi A. Role of catalase and hydroxyl radicals in the oxidation of methanol by rat liver microsomes. Biochem Pharmacol. 1982 Feb 1; 31(3):329-35.
      View in: PubMed
    288. Cederbaum AI, Dicker E. Evaluation of the role of acetaldehyde in the actions of ethanol on gluconeogenesis by comparison with the effects of crotonol and crotonaldehyde. Alcohol Clin Exp Res. 1982; 6(1):100-9.
      View in: PubMed
    289. Cederbaum AI, Dicker E. Effect of cyanamide on the metabolism of ethanol and acetaldehyde and on gluconeogenesis by isolated rat hepatocytes. Biochem Pharmacol. 1981 Nov 15; 30(22):3079-88.
      View in: PubMed
    290. Klein SM, Cohen G, Cederbaum AI. Production of formaldehyde during metabolism of dimethyl sulfoxide by hydroxyl radical generating systems. Biochemistry. 1981 Oct 13; 20(21):6006-12.
      View in: PubMed
    291. Cederbaum AI, Qureshi A, Messenger P. Oxidation of isopropanol by rat liver microsomes: possible role of hydroxyl radicals. Biochem Pharmacol. 1981 Apr 15; 30(8):825-31.
      View in: PubMed
    292. Cederbaum AI. The effect of cyanamide on acetaldehyde oxidation by isolated rat liver mitochondria and on the inhibition of pyruvate oxidation by acetaldehyde. Alcohol Clin Exp Res. 1981 Jan; 5(1):38-44.
      View in: PubMed
    293. Sun AS, Cederbaum AI. Oxidoreductase activities in normal rat liver, tumor-bearing rat liver, and hepatoma HC-252. Cancer Res. 1980 Dec; 40(12):4677-81.
      View in: PubMed
    294. Cederbaum AI, Cohen G. Oxidative demethylation of t-butyl alcohol by rat liver microsomes. Biochem Biophys Res Commun. 1980 Nov 28; 97(2):730-6.
      View in: PubMed
    295. Kumar S, Cederbaum AI, Pletka PG. Renal cell carcinoma in polycystic kidneys: case report and review of literature. J Urol. 1980 Nov; 124(5):708-9.
      View in: PubMed
    296. Cederbaum AI, Dicker E, Cohen G. Role of hydroxyl radicals in the iron-ethylenediaminetetraacetic acid mediated stimulation of microsomal oxidation of ethanol. Biochemistry. 1980 Aug 5; 19(16):3698-704.
      View in: PubMed
    297. Klein SM, Cohen G, Cederbaum AI. The interaction of hydroxyl radicals with dimethylsulfoxide produces formaldehyde. FEBS Lett. 1980 Jul 28; 116(2):220-2.
      View in: PubMed
    298. Cederbaum AI. Regulation of pathways of alcohol metabolism by the liver. Mt Sinai J Med. 1980 May-Jun; 47(3):317-28.
      View in: PubMed
    299. Cohen G, Cederbaum AI. Microsomal metabolism of hydroxyl radical scavenging agents: relationship to the microsomal oxidation of alcohols. Arch Biochem Biophys. 1980 Feb; 199(2):438-47.
      View in: PubMed
    300. Cederbaum AI, Dicker E, Cohen G. Role of hydroxyl radicals in microsomal oxidation of alcohols. Adv Exp Med Biol. 1980; 132:1-10.
      View in: PubMed
    301. Cederbaum AI, Miwa G, Cohen G, Lu AY. Production of hydroxyl radicals and their role in the oxidation of ethanol by a reconstituted microsomal system containing cytochrome P-450 purified from phenobarbital-treated rats. Biochem Biophys Res Commun. 1979 Dec 14; 91(3):747-54.
      View in: PubMed
    302. Cederbaum AI, Dicker E. The effect of acetaldehyde on gluconeogenesis from xylitol, sorbitol, and fructose by isolated rat liver cells. Arch Biochem Biophys. 1979 Oct 15; 197(2):415-23.
      View in: PubMed
    303. Cohen G, Cederbaum AI. Chemical evidence for production of hydroxyl radicals during microsomal electron transfer. Science. 1979 Apr 6; 204(4388):66-8.
      View in: PubMed
    304. Cederbaum AI, Dicker E, Rubin E, Cohen G. Effect of thiourea on microsomal oxidation of alcohols and associated microsomal functions. Biochemistry. 1979 Apr 3; 18(7):1187-91.
      View in: PubMed
    305. Cederbaum AI, Dicker E. The effect of pargyline on the metabolism of ethanol and acetaldehyde by isolated rat liver cells. Arch Biochem Biophys. 1979 Apr 1; 193(2):551-9.
      View in: PubMed
    306. Cederbaum AI, Dicker E. A comparison of the effects of ethanol and acetaldehyde on glucose production from various precursors by isolated rat liver cells. Curr Alcohol. 1979; 7:71-81.
      View in: PubMed
    307. Cederbaum AI, Dicker E, Cohen G. Effect of hydroxyl radical scavengers on microsomal oxidation of alcohols and on associated microsomal reactions. Biochemistry. 1978 Jul 25; 17(15):3058-64.
      View in: PubMed
    308. Cederbaum AI, Zimbler S. Bleeding diatheses in the orthopedic patient. Orthop Clin North Am. 1978 Jul; 9(3):781-90.
      View in: PubMed
    309. Cederbaum AI. The effect of calcium on the oxidation of acetaldehyde by rat liver mitochondria. Life Sci. 1978 Jan; 22(1):111-25.
      View in: PubMed
    310. Cederbaum AI, Dicker E, Lieber CS, Rubin E. Ethanol oxidation by isolated hepatocytes from ethanol-treated and control rats; factors contributing to the metabolic adaptation after chronic ethanol consumption. Biochem Pharmacol. 1978 Jan 1; 27(1):7-15.
      View in: PubMed
    311. Cederbaum AI, Dicker E, Rubin E, Cohen G. The effect of dimethylsulfoxide and other hydroxyl radical scavengers on the oxidation of ethanol by rat liver microsomes. Biochem Biophys Res Commun. 1977 Oct 24; 78(4):1254-62.
      View in: PubMed
    312. Cederbaum AI, Dicker E, Rubin E. Transfer and reoxidation of reducing equivalents as the rate-limiting steps in the oxidation of ethanol by liver cells isolated from fed and fasted rats. Arch Biochem Biophys. 1977 Oct; 183(2):638-46.
      View in: PubMed
    313. Pope RM, Cederbaum AI, Lewis W, Mannik M. Immunoblastic lymphadenopathy presenting as respiratory insufficiency. Am J Med Sci. 1977 Sep-Oct; 274(2):213-9.
      View in: PubMed
    314. Cederbaum AI, Rubin E. The oxidation of acetaldehyde by isolated mitochondria from various organs of the rat and hepatocellular carcinoma. Arch Biochem Biophys. 1977 Feb; 179(1):46-66.
      View in: PubMed
    315. Cederbaum AI, Dicker E, Lieber CS, Rubin E. Factors contributing to the adaptive increase in ethanol metabolism due to chronic consumption of ethanol. Alcohol Clin Exp Res. 1977 Jan; 1(1):27-31.
      View in: PubMed
    316. Cederbaum AI, Rubin E. Mechanism of the protective action of cysteine and penicillamine against acetaldehyde-induced mitochondrial injury. Biochem Pharmacol. 1976 Oct 1; 25(19):2179-85.
      View in: PubMed
    317. Cederbaum AI, Lieber CS, Rubin E. Effect of chronic ethanol consumption and acetaldehyde on partial reactions of oxidative phosphorylation and CO2 production from citric acid cycle intermediates. Arch Biochem Biophys. 1976 Oct; 176(2):525-38.
      View in: PubMed
    318. Cederbaum AI, Becker FF, Rubin E. Ethanol metabolism by a transplantable hepatocellular carcinoma. Role of microsomes and mitochondria. J Biol Chem. 1976 Sep 10; 251(17):5366-74.
      View in: PubMed
    319. Cederbaum AI, Rubin E. Fatty acid oxidation, substrate shuttles, and activity of the citric acid cycle in hepatocellular carcinomas of varying differentiation. Cancer Res. 1976 Sep; 36(9 pt.1):2980-7.
      View in: PubMed
    320. Cederbaum AI, Rubin E. Kinetic properties of alcohol dehydrogenase in hepatocellular carcinoma and normal tissues of rat. Cancer Res. 1976 Jul; 36(7 PT 1):2274-7.
      View in: PubMed
    321. Cederbaum AI, Madhavan TV, Rubin E. Effect of chronic clofibrate administration on mitochondrial fatty acid oxidation. Biochem Pharmacol. 1976 Jun 1; 25(11):1285-92.
      View in: PubMed
    322. Cederbaum AI, Blatt PM, Roberts HR. Intravascular coagulation with use of human prothrombin complex concentrates. Ann Intern Med. 1976 Jun; 84(6):683-7.
      View in: PubMed
    323. Cederbaum AI, Rubin E. Protective effect of cysteine on the inhibition of mitochondrial functions by acetaldehyde. Biochem Pharmacol. 1976 Apr 15; 25(8):963-73.
      View in: PubMed
    324. Cederbaum AI, Pietrusko R, Hempel J, Becker FF, Rubin E. Characterization of a nonhepatic alcohol dehydrogenase from rat hepatocellular carcinoma and stomach. Arch Biochem Biophys. 1975 Nov; 171(1):348-60.
      View in: PubMed
    325. Cederbaum AI, Rubin E. Molecular injury to mitochondria produced by ethanol and acetaldehyde. Fed Proc. 1975 Oct; 34(11):2045-51.
      View in: PubMed
    326. Graham JB, Barrow ES, Roberts HR, Webster WP, Blatt PM, Buchanan P, Cederbaum AI, Allain JP, Barrett DA, Gralnick HR. Dominant inheritance of hemophilia A in three generations of women. Blood. 1975 Aug; 46(2):175-88.
      View in: PubMed
    327. Cederbaum AI, Lieber CS, Beattie DS, Rubin E. Effect of chronic ethanol ingestion on fatty acid oxidation by hepatic mitochondria. J Biol Chem. 1975 Jul 10; 250(13):5122-9.
      View in: PubMed
    328. Cederbaum AI, Lieber CS, Rubin E. Effect of acetaldehyde on fatty acid oxidation and ketogenesis by hepatic mitochondria. Arch Biochem Biophys. 1975 Jul; 169(1):29-41.
      View in: PubMed
    329. Cederbaum AI, Rubin E. Differential effects of acetate on palmitate and octanoate oxidation: segregation of acetyl CoA pools. Arch Biochem Biophys. 1975 Feb; 166(2):618-28.
      View in: PubMed
    330. Cederbaum AI, Lieber CS, Rubin E. Effects of chronic ethanol treatment of mitochondrial functions damage to coupling site I. Arch Biochem Biophys. 1974 Dec; 165(2):560-9.
      View in: PubMed
    331. Cederbaum AI, Rubin E. Effects of clofibrate on mitochondrial function. Biochem Pharmacol. 1974 Jul 15; 23(14):1985-96.
      View in: PubMed
    332. Cederbaum AI, Rubin E. Effects of pyrazole, 4-bromopyrazole and 4-methylpyrazole on mitochondrial function. Biochem Pharmacol. 1974 Jan 15; 23(2):203-13.
      View in: PubMed
    333. Cederbaum AI, Lieber CS, Rubin E. Effect of acetaldehyde on activity of shuttles for the transport of reducing equivalents into the mitochondria. FEBS Lett. 1973 Nov 15; 37(1):89-92.
      View in: PubMed
    334. Weiss AE, Cederbaum AI. Diagnosis and treatment of intravascular coagulation. Am Fam Physician. 1973 Nov; 8(5):110-9.
      View in: PubMed
    335. Cederbaum AI, Lieber CS, Beattie DS, Rubin E. Characterization of shuttle mechanisms for the transport of reducing equivalents into mitochondria. Arch Biochem Biophys. 1973 Oct; 158(2):763-81.
      View in: PubMed
    336. Gang H, Cederbaum AI, Rubin E. Stereospecificity of ethanol oxidation. Biochem Biophys Res Commun. 1973 Sep 5; 54(1):264-9.
      View in: PubMed
    337. Cederbaum AI, Lieber CS, Toth A, Beattie DS, Rubin E. Effects of ethanol and fat on the transport of reducing equivalents into rat liver mitochondria. J Biol Chem. 1973 Jul 25; 248(14):4977-86.
      View in: PubMed
    338. Neal WR, Tayloe DT, Cederbaum AI, Roberts HR. Detection of genetic variants of haemophilia B with an immunosorbent technique. Br J Haematol. 1973 Jul; 25(1):63-8.
      View in: PubMed
    339. Cederbaum AI, Rubin E. Role of citrate in stimulation of the fatty acid shuttle for the transport of reducing equivalents into mitochondria. Biochem Biophys Res Commun. 1973 Jun 8; 52(3):980-6.
      View in: PubMed
    340. Butow RA, Ferguson MJ, Cederbaum A. Low-temperature induction of respiratory deficiency in yeast mutants. Biochemistry. 1973 Jan 2; 12(1):158-64.
      View in: PubMed
    341. Cederbaum AI, Lieber CS, Beattie DS, Rubin E. Effect of chronic ethanol ingestion on mitochondrial permeability and the transport of reducing equivalents. Biochem Biophys Res Commun. 1972 Nov 1; 49(3):649-55.
      View in: PubMed
    342. Roberts HR, Cederbaum AI. The liver and blood coagulation: physiology and pathology. Gastroenterology. 1972 Aug; 63(2):297-320.
      View in: PubMed
    343. Cederbaum AI, Wainio WW. Binding of iron and copper to bovine heart mitochondria. I. Quantitative aspects and stability. J Biol Chem. 1972 Jul 25; 247(14):4593-603.
      View in: PubMed
    344. Cederbaum AI, Wainio WW. Binding of iron and copper to bovine heart mitochondria. 3. Role of mitochondrial phospholipids and thiols. J Biol Chem. 1972 Jul 25; 247(14):4615-20.
      View in: PubMed
    345. Cederbaum AI, Wainio WW. Binding of iron and copper to bovine heart mitochondria. II. Effect of mitochondrial metabolism. J Biol Chem. 1972 Jul 25; 247(14):4604-14.
      View in: PubMed
    Cederbaum's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts
    _
    Co-Authors
    _
    Similar People
    _
    Same Department
     
    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067