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Last Name
Institution

John Roboz

TitlePROFESSOR
InstitutionMount Sinai
DepartmentHematology and Medical Oncology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ohnuma T, Lehrer D, Ren C, Cho SY, Maniar M, Silverman L, Sung M, Gretz HF, Benisovich V, Navada S, Akahoho E, Wilck E, Taft DR, Roboz J, Wilhelm F, Holland JF. Phase 1 study of intravenous rigosertib (ON 01910.Na), a novel benzyl styryl sulfone structure producing G2/M arrest and apoptosis, in adult patients with advanced cancer. Am J Cancer Res. 2013; 3(3):323-38.
      View in: PubMed
    2. Cho SY, Cosenza SC, Pallela V, Panda G, Reddy MV, Reddy EP, Roboz J. Determination of the glucuronide metabolite of ON 013100, a benzylstyrylsulfone antineoplastic drug, in colon cancer cells using LC/MS/MS. J Pharm Biomed Anal. 2013 Mar 5; 75:138-44.
      View in: PubMed
    3. Cho SY, Ohnuma T, Silverman LR, Holland JF, Roboz J. Discontinuous drug binding to proteins: binding of an antineoplastic benzyl styryl sulfone to albumin and enzymes in vitro and in phase I clinical trials. Drug Metab Dispos. 2010 Sep; 38(9):1480-5.
      View in: PubMed
    4. Cho SY, Xu M, Roboz J, Lu M, Mascarenhas J, Hoffman R. The effect of CXCL12 processing on CD34+ cell migration in myeloproliferative neoplasms. Cancer Res. 2010 Apr 15; 70(8):3402-10.
      View in: PubMed
    5. Wang H, Li H, Moore LB, Johnson MD, Maglich JM, Goodwin B, Ittoop OR, Wisely B, Creech K, Parks DJ, Collins JL, Willson TM, Kalpana GV, Venkatesh M, Xie W, Cho SY, Roboz J, Redinbo M, Moore JT, Mani S. The phytoestrogen coumestrol is a naturally occurring antagonist of the human pregnane X receptor. Mol Endocrinol. 2008 Apr; 22(4):838-57.
      View in: PubMed
    6. Roboz J. Mass spectrometry in diagnostic oncoproteomics. Cancer Invest. 2005; 23(5):465-78.
      View in: PubMed
    7. Schlesinger M, Jiang JD, Roboz JP, Denner L, Ling YH, Holland JF, Bekesi JG. 3-m-bromoacetylamino benzoic acid ethyl ester: a new cancericidal agent that activates the apoptotic pathway through caspase-9. Biochem Pharmacol. 2000 Dec 1; 60(11):1693-702.
      View in: PubMed
    8. Jiang JD, Schlesinger M, Sacks H, Mildvan D, Roboz JP, Bekesi JG. Concentrations of soluble CD95 and CD8 antigens in the plasma and levels of CD8+CD95+, CD8+CD38+, and CD4+CD95+ T cells are markers for HIV-1 infection and clinical status. J Clin Immunol. 1997 Mar; 17(2):185-92.
      View in: PubMed
    9. Schlesinger M, Peters V, Jiang JD, Roboz JP, Bekesi JG. Increased expression of activation markers on CD8 lymphocytes in children with human immunodeficiency virus-1 infection. Pediatr Res. 1995 Sep; 38(3):390-6.
      View in: PubMed
    10. Schlesinger M, Chu FN, Badamchian M, Jiang JD, Roboz JP, Goldstein AL, Bekesi JG. A distinctive form of soluble CD8 is secreted by stimulated CD8+ cells in HIV-1-infected and high-risk individuals. Clin Immunol Immunopathol. 1994 Nov; 73(2):252-60.
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    11. Fischbein A, Tsang P, Luo JC, Roboz JP, Jiang JD, Bekesi JG. Phenotypic aberrations of CD3+ and CD4+ cells and functional impairments of lymphocytes at low-level occupational exposure to lead. Clin Immunol Immunopathol. 1993 Feb; 66(2):163-8.
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    12. Yagi MJ, Joesten ME, Wallace J, Roboz JP, Bekesi JG. Human immunodeficiency virus type 1 (HIV-1) genomic sequences and distinct changes in CD8+ lymphocytes precede detectable levels of HIV-1 antibodies in high-risk homosexuals. J Infect Dis. 1991 Jul; 164(1):183-8.
      View in: PubMed
    13. Sei Y, Tsang PH, Chu FN, Wallace I, Roboz JP, Sarin PS, Bekesi JG. Inverse relationship between HIV-1 p24 antigenemia, anti-p24 antibody and neutralizing antibody response in all stages of HIV-1 infection. Immunol Lett. 1989 Feb; 20(3):223-30.
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    14. Sei Y, Tsang PH, Roboz JP, Sarin PS, Wallace JI, Bekesi JG. Neutralizing antibodies as a prognostic indicator in the progression of acquired immune deficiency syndrome (AIDS)-related disorders: a double-blind study. J Clin Immunol. 1988 Nov; 8(6):464-72.
      View in: PubMed
    15. Tsang PH, Roboz JP, Holland JF, Bekesi JG. Effector lymphocyte response to homologous tumor antigens in various stages of malignant disease as monitored by leukocyte adherence inhibition--cell mediated immunity (LAI-CMI). Immunol Lett. 1988 Jan; 17(1):63-70.
      View in: PubMed
    16. Bekesi JG, Tsang PH, Wallace JI, Roboz JP. Immunorestorative properties of isoprinosine in the treatment of patients at high risk of developing ARC or AIDS. J Clin Lab Immunol. 1987 Dec; 24(4):155-61.
      View in: PubMed
    17. Tsang PH, Wallace JI, Roboz JP, Sei Y, Bekesi JG. Immune dysfunctions and therapeutic interventions in patients with acquired immune deficiency syndrome and AIDS-related complex. Mt Sinai J Med. 1987 Feb; 54(2):121-8.
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    18. Tsang PH, Roboz JP, Bekesi JG. Recent advances in cellular aberrations in the acquired immune deficiency syndrome. J Exp Pathol. 1987; 3(4):633-51.
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    19. Bekesi JG, Roboz JP, Fischbein A, Mason P. Immunotoxicology: environmental contamination by polybrominated biphenyls and immune dysfunction among residents of the State of Michigan. Cancer Detect Prev Suppl. 1987; 1:29-37.
      View in: PubMed
    20. Bekesi JG, Tsang P, Roboz JP. The mechanism and modulation of immune dysfunction in AIDS associated syndromes. Adv Exp Med Biol. 1985; 187:141-50.
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    21. Bekesi JG, Tsang P, Lew F, Roboz JP, Teirstein A, Selikoff IJ. Functional integrity of T, B, and natural killer cells in homosexual subjects with prodromata and in patients with AIDS. Ann N Y Acad Sci. 1984; 437:28-38.
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    22. Bekesi JG, Roboz JP. Prophylactic and therapeutic application of interferon in spontaneous leukemia in AKR mice. Tex Rep Biol Med. 1981-1982; 41:614-20.
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    23. Bekesi JG, Anderson HA, Roboz JP, Roboz J, Fischbein A, Selikoff IJ, Holland JF. Immunologic dysfunction among PBB-exposed Michigan dairy farmers. Ann N Y Acad Sci. 1979 May 31; 320:717-28.
      View in: PubMed
    24. Bekesi JG, Roboz J, Anderson HA, Roboz JP, Fischbein AS, Selikoff IJ, Holland JF. Impaired immune function and identification of polybrominated biphenyls (PBB) in blood compartments of exposed Michigan dairy farmers and chemical workers. Drug Chem Toxicol. 1979; 2(1-2):179-91.
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    25. Bekesi JG, Holland JF, Roboz JP. Specific immunotherapy with neuraminidase-modified leukemic cells: experimental and clinical trials. Med Clin North Am. 1977 Sep; 61(5):1083-100.
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    26. Bekesi JG, Roboz JP, Holland JF. Characteristics of immunity induced by neuraminidase-treated lymphosarcoma cells in C3H (MTV+) and C3H (MTV-) mice. Isr J Med Sci. 1976 Apr-May; 12(4-5):288-303.
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    27. Bekesi JG, Roboz JP, Zimmerman E, Holland JF. Treatment of spontaneous leukemia in AKR mice with chemotherapy, immunotherapy, or interferon. Cancer Res. 1976 Feb; 36(2 pt 2):631-9.
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    28. Bekesi JG, Roboz JP, Holland JF. Therapeutic effectiveness of neuraminidase-treated tumor cells as an immunogen in man and experimental animals with leukemia. Ann N Y Acad Sci. 1976; 277(00):313-31.
      View in: PubMed
    29. Bekesi JG, Roboz JP, Holland JF. Chemoimmunotherapy in human and experimental leukemia. Bibl Haematol. 1975 Oct; (43):524-5.
      View in: PubMed
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