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Last Name
Institution

Thomas P. Zwaka

TitleSENIOR FACULTY
InstitutionMount Sinai
DepartmentDevelopmental and Regenerative Biology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wagner RT, Zwaka TP. Development: Sketch for a Theory of Oct4. Curr Biol. 2013 Nov 18; 23(22):R1014-6.
      View in: PubMed
    2. Dejosez M, Ura H, Brandt VL, Zwaka TP. Safeguards for cell cooperation in mouse embryogenesis shown by genome-wide cheater screen. Science. 2013 Sep 27; 341(6153):1511-4.
      View in: PubMed
    3. Zwaka TP. Pluripotency network in embryonic stem cells: maybe Leibniz was right all along. Cell Stem Cell. 2012 Oct 5; 11(4):441-2.
      View in: PubMed
    4. Bao S, Leitch HG, Gillich A, Nichols J, Tang F, Kim S, Lee C, Zwaka T, Li X, Surani MA. The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells. Cell Stem Cell. 2012 Jul 6; 11(1):110-7.
      View in: PubMed
    5. Dejosez M, Zwaka TP. Pluripotency and nuclear reprogramming. Annu Rev Biochem. 2012; 81:737-65.
      View in: PubMed
    6. Jain AK, Allton K, Iacovino M, Mahen E, Milczarek RJ, Zwaka TP, Kyba M, Barton MC. p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells. PLoS Biol. 2012; 10(2):e1001268.
      View in: PubMed
    7. Chu LF, Surani MA, Jaenisch R, Zwaka TP. Blimp1 expression predicts embryonic stem cell development in vitro. Curr Biol. 2011 Oct 25; 21(20):1759-65.
      View in: PubMed
    8. Gu D, Tonthat NK, Lee M, Ji H, Bhat KP, Hollingsworth F, Aldape KD, Schumacher MA, Zwaka TP, McCrea PD. Caspase-3 cleavage links delta-catenin to the novel nuclear protein ZIFCAT. J Biol Chem. 2011 Jul 1; 286(26):23178-88.
      View in: PubMed
    9. Zwaka TP. Unraveling the score of the enhancer symphony. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21240-1.
      View in: PubMed
    10. Zwaka TP. The stem cell "tunnel" effect. Mol Ther. 2010 Dec; 18(12):2043-4.
      View in: PubMed
    11. Zwaka TP. Stem cells: Troublesome memories. Nature. 2010 Sep 16; 467(7313):280-1.
      View in: PubMed
    12. Dejosez M, Levine SS, Frampton GM, Whyte WA, Stratton SA, Barton MC, Gunaratne PH, Young RA, Zwaka TP. Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells. Genes Dev. 2010 Jul 15; 24(14):1479-84.
      View in: PubMed
    13. Zwaka TP. Stem cell vaccination against cancer: fighting fire with fire? Mol Ther. 2010 Jan; 18(1):8-9.
      View in: PubMed
    14. Zwaka TP. Reduce, reuse, reprogram. Nat Methods. 2010 Jan; 7(1):39-40.
      View in: PubMed
    15. McKay RD, van der Kooy D, Zwaka TP, Lin H. Stem cells in 2009. Cell Stem Cell. 2009 Nov 6; 5(5):483-9.
      View in: PubMed
    16. Zwaka TP. Ronin and caspases in embryonic stem cells: a new perspective on regulation of the pluripotent state. Cold Spring Harb Symp Quant Biol. 2008; 73:163-9.
      View in: PubMed
    17. Chen YT, Dejosez M, Zwaka TP, Behringer RR. H1 and H9 human embryonic stem cell lines are heterozygous for the ABO locus. Stem Cells Dev. 2008 Oct; 17(5):853-5.
      View in: PubMed
    18. Dejosez M, Krumenacker JS, Zitur LJ, Passeri M, Chu LF, Songyang Z, Thomson JA, Zwaka TP. Ronin is essential for embryogenesis and the pluripotency of mouse embryonic stem cells. Cell. 2008 Jun 27; 133(7):1162-74.
      View in: PubMed
    19. Fujita J, Crane AM, Souza MK, Dejosez M, Kyba M, Flavell RA, Thomson JA, Zwaka TP. Caspase activity mediates the differentiation of embryonic stem cells. Cell Stem Cell. 2008 Jun 5; 2(6):595-601.
      View in: PubMed
    20. Zwaka TP. Keeping the noise down in ES cells. Cell. 2006 Dec 29; 127(7):1301-2.
      View in: PubMed
    21. Zimmermann O, Kochs M, Zwaka TP, Bienek-Ziolkowski M, Höher M, Hombach V, Torzewski J. Prognostic role of myocardial tumor necrosis factor-alpha and terminal complement complex expression in patients with dilated cardiomyopathy. Eur J Heart Fail. 2007 Jan; 9(1):51-4.
      View in: PubMed
    22. Zimmermann O, Zwaka TP, Marx N, Torzewski M, Bucher A, Guilliard P, Hannekum A, Hombach V, Torzewski J. Serum starvation and growth factor receptor expression in vascular smooth muscle cells. J Vasc Res. 2006; 43(2):157-65.
      View in: PubMed
    23. Zwaka TP. Breathing chromatin in pluripotent stem cells. Dev Cell. 2006 Jan; 10(1):1-2.
      View in: PubMed
    24. Zimmermann O, Kochs M, Zwaka TP, Kaya Z, Lepper PM, Bienek-Ziolkowski M, Hoher M, Hombach V, Torzewski J. Myocardial biopsy based classification and treatment in patients with dilated cardiomyopathy. Int J Cardiol. 2005 Sep 15; 104(1):92-100.
      View in: PubMed
    25. Zwaka TP, Thomson JA. Differentiation of human embryonic stem cells occurs through symmetric cell division. Stem Cells. 2005 Feb; 23(2):146-9.
      View in: PubMed
    26. Zwaka TP, Thomson JA. A germ cell origin of embryonic stem cells? Development. 2005 Jan; 132(2):227-33.
      View in: PubMed
    27. Draper JS, Smith K, Gokhale P, Moore HD, Maltby E, Johnson J, Meisner L, Zwaka TP, Thomson JA, Andrews PW. Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat Biotechnol. 2004 Jan; 22(1):53-4.
      View in: PubMed
    28. Zwaka TP, Torzewski J, Hoeflich A, Déjosez M, Kaiser S, Hombach V, Jehle PM. The terminal complement complex inhibits apoptosis in vascular smooth muscle cells by activating an autocrine IGF-1 loop. FASEB J. 2003 Jul; 17(10):1346-8.
      View in: PubMed
    29. Zwaka TP, Thomson JA. Homologous recombination in human embryonic stem cells. Nat Biotechnol. 2003 Mar; 21(3):319-21.
      View in: PubMed
    30. Xu RH, Chen X, Li DS, Li R, Addicks GC, Glennon C, Zwaka TP, Thomson JA. BMP4 initiates human embryonic stem cell differentiation to trophoblast. Nat Biotechnol. 2002 Dec; 20(12):1261-4.
      View in: PubMed
    31. Zwaka TP, Manolov D, Ozdemir C, Marx N, Kaya Z, Kochs M, Höher M, Hombach V, Torzewski J. Complement and dilated cardiomyopathy: a role of sublytic terminal complement complex-induced tumor necrosis factor-alpha synthesis in cardiac myocytes. Am J Pathol. 2002 Aug; 161(2):449-57.
      View in: PubMed
    32. Zwaka TP, Hombach V, Torzewski J. C-reactive protein-mediated low density lipoprotein uptake by macrophages: implications for atherosclerosis. Circulation. 2001 Mar 6; 103(9):1194-7.
      View in: PubMed
    33. Engers R, Zwaka TP, Gohr L, Weber A, Gerharz CD, Gabbert HE. Tiam1 mutations in human renal-cell carcinomas. Int J Cancer. 2000 Nov 1; 88(3):369-76.
      View in: PubMed
    34. Torzewski M, Rist C, Mortensen RF, Zwaka TP, Bienek M, Waltenberger J, Koenig W, Schmitz G, Hombach V, Torzewski J. C-reactive protein in the arterial intima: role of C-reactive protein receptor-dependent monocyte recruitment in atherogenesis. Arterioscler Thromb Vasc Biol. 2000 Sep; 20(9):2094-9.
      View in: PubMed
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067