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Marc Birtwistle

TitleASSISTANT PROFESSOR
InstitutionMount Sinai
DepartmentPharmacology and Systems Therapeutics
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     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. von Thun A, Preisinger C, Rath O, Schwarz JP, Ward C, Monsefi N, Rodríguez J, Garcia-Munoz A, Birtwistle M, Bienvenut W, Anderson KI, Kolch W, von Kriegsheim A. Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity. Mol Cell Biol. 2013 Nov; 33(22):4526-37.
      View in: PubMed
    2. Greene J, Birtwistle MR, Ignatowicz L, Rempala GA. Bayesian multivariate Poisson abundance models for T-cell receptor data. J Theor Biol. 2013 Jun 7; 326:1-10.
      View in: PubMed
    3. Birtwistle MR, von Kriegsheim A, Dobrzynski M, Kholodenko BN, Kolch W. Mammalian protein expression noise: scaling principles and the implications for knockdown experiments. Mol Biosyst. 2012 Nov; 8(11):3068-76.
      View in: PubMed
    4. Birtwistle MR, Rauch J, Kiyatkin A, Aksamitiene E, Dobrzynski M, Hoek JB, Kolch W, Ogunnaike BA, Kholodenko BN. Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise. BMC Syst Biol. 2012; 6:109.
      View in: PubMed
    5. Shull AY, Latham-Schwark A, Ramasamy P, Leskoske K, Oroian D, Birtwistle MR, Buckhaults PJ. Novel somatic mutations to PI3K pathway genes in metastatic melanoma. PLoS One. 2012; 7(8):e43369.
      View in: PubMed
    6. von Thun A, Birtwistle M, Kalna G, Grindlay J, Strachan D, Kolch W, von Kriegsheim A, Norman JC. ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-ß2. J Cell Sci. 2012 Mar 15; 125(Pt 6):1465-77.
      View in: PubMed
    7. Birtwistle MR, von Kriegsheim A, Kida K, Schwarz JP, Anderson KI, Kolch W. Linear approaches to intramolecular Förster resonance energy transfer probe measurements for quantitative modeling. PLoS One. 2011; 6(11):e27823.
      View in: PubMed
    8. Bruning U, Fitzpatrick SF, Frank T, Birtwistle M, Taylor CT, Cheong A. NF?B and HIF display synergistic behaviour during hypoxic inflammation. Cell Mol Life Sci. 2012 Apr; 69(8):1319-29.
      View in: PubMed
    9. Birtwistle MR, Kolch W. Biology using engineering tools: the negative feedback amplifier. Cell Cycle. 2011 Jul 1; 10(13):2069-76.
      View in: PubMed
    10. Matallanas D, Birtwistle M, Romano D, Zebisch A, Rauch J, von Kriegsheim A, Kolch W. Raf family kinases: old dogs have learned new tricks. Genes Cancer. 2011 Mar; 2(3):232-60.
      View in: PubMed
    11. Sturm OE, Orton R, Grindlay J, Birtwistle M, Vyshemirsky V, Gilbert D, Calder M, Pitt A, Kholodenko B, Kolch W. The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier. Sci Signal. 2010; 3(153):ra90.
      View in: PubMed
    12. Nakakuki T, Birtwistle MR, Saeki Y, Yumoto N, Ide K, Nagashima T, Brusch L, Ogunnaike BA, Okada-Hatakeyama M, Kholodenko BN. Ligand-specific c-Fos expression emerges from the spatiotemporal control of ErbB network dynamics. Cell. 2010 May 28; 141(5):884-96.
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    13. von Kriegsheim A, Baiocchi D, Birtwistle M, Sumpton D, Bienvenut W, Morrice N, Yamada K, Lamond A, Kalna G, Orton R, Gilbert D, Kolch W. Cell fate decisions are specified by the dynamic ERK interactome. Nat Cell Biol. 2009 Dec; 11(12):1458-64.
      View in: PubMed
    14. Kholodenko BN, Birtwistle MR. Four-dimensional dynamics of MAPK information processing systems. Wiley Interdiscip Rev Syst Biol Med. 2009 Jul-Aug; 1(1):28-44.
      View in: PubMed
    15. Birtwistle MR, Kholodenko BN. Endocytosis and signalling: a meeting with mathematics. Mol Oncol. 2009 Aug; 3(4):308-20.
      View in: PubMed
    16. Birtwistle MR, Hatakeyama M, Yumoto N, Ogunnaike BA, Hoek JB, Kholodenko BN. Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses. Mol Syst Biol. 2007; 3:144.
      View in: PubMed
    17. Birtwistle M, Ottridge M. General practice and drug misuse. Br J Gen Pract. 1992 Oct; 42(363):442.
      View in: PubMed
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067