Keywords
Last Name
Institution

Robert Fisher

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentStructural and Chemical Biology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Sansó M, Fisher RP. Modelling the CDK-dependent transcription cycle in fission yeast. Biochem Soc Trans. 2013 Dec 1; 41(6):1660-5.
      View in: PubMed
    2. Schachter MM, Fisher RP. The CDK-activating kinase Cdk7: taking yes for an answer. Cell Cycle. 2013 Oct 15; 12(20):3239-40.
      View in: PubMed
    3. Schachter MM, Merrick KA, Larochelle S, Hirschi A, Zhang C, Shokat KM, Rubin SM, Fisher RP. A Cdk7-Cdk4 T-loop phosphorylation cascade promotes G1 progression. Mol Cell. 2013 Apr 25; 50(2):250-60.
      View in: PubMed
    4. Fisher RP. The CDK Network: Linking Cycles of Cell Division and Gene Expression. Genes Cancer. 2012 Nov; 3(11-12):731-8.
      View in: PubMed
    5. Larochelle S, Amat R, Glover-Cutter K, Sansó M, Zhang C, Allen JJ, Shokat KM, Bentley DL, Fisher RP. Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II. Nat Struct Mol Biol. 2012 Nov; 19(11):1108-15.
      View in: PubMed
    6. Wohlbold L, Merrick KA, De S, Amat R, Kim JH, Larochelle S, Allen JJ, Zhang C, Shokat KM, Petrini JH, Fisher RP. Chemical genetics reveals a specific requirement for Cdk2 activity in the DNA damage response and identifies Nbs1 as a Cdk2 substrate in human cells. PLoS Genet. 2012 Aug; 8(8):e1002935.
      View in: PubMed
    7. Sansó M, Lee KM, Viladevall L, Jacques PÉ, Pagé V, Nagy S, Racine A, St Amour CV, Zhang C, Shokat KM, Schwer B, Robert F, Fisher RP, Tanny JC. A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast. PLoS Genet. 2012; 8(8):e1002822.
      View in: PubMed
    8. Merrick KA, Fisher RP. Why minimal is not optimal: driving the mammalian cell cycle--and drug discovery--with a physiologic CDK control network. Cell Cycle. 2012 Jul 15; 11(14):2600-5.
      View in: PubMed
    9. St Amour CV, Sansó M, Bösken CA, Lee KM, Larochelle S, Zhang C, Shokat KM, Geyer M, Fisher RP. Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition. Mol Cell Biol. 2012 Jul; 32(13):2372-83.
      View in: PubMed
    10. Merrick KA, Wohlbold L, Zhang C, Allen JJ, Horiuchi D, Huskey NE, Goga A, Shokat KM, Fisher RP. Switching Cdk2 on or off with small molecules to reveal requirements in human cell proliferation. Mol Cell. 2011 Jun 10; 42(5):624-36.
      View in: PubMed
    11. Osawa R, Alexander BD, Forrest GN, Lyon GM, Somani J, del Busto R, Pruett TL, Sifri CD, Limaye AP, Klintmalm GB, Pursell K, Stosor V, Morris MI, Dowdy LA, Kalil AC, Garcia-Diaz J, Orloff SL, Houston SH, Wray D, Huprikar S, Johnson LB, Razonable RR, Fisher RA, Wagener MM, Husain S, Singh N. Geographic differences in disease expression of cryptococcosis in solid organ transplant recipients in the United States. Ann Transplant. 2010 Oct-Dec; 15(4):77-83.
      View in: PubMed
    12. Merrick KA, Fisher RP. Putting one step before the other: distinct activation pathways for Cdk1 and Cdk2 bring order to the mammalian cell cycle. Cell Cycle. 2010 Feb 15; 9(4):706-14.
      View in: PubMed
    13. Fisher RP. Coming full circle: cyclin-dependent kinases as anti-cancer drug targets. Subcell Biochem. 2010; 50:1-15.
      View in: PubMed
    14. Fujii K, Munshi UM, Ablan SD, Demirov DG, Soheilian F, Nagashima K, Stephen AG, Fisher RJ, Freed EO. Functional role of Alix in HIV-1 replication. Virology. 2009 Sep 1; 391(2):284-92.
      View in: PubMed
    15. Wohlbold L, Fisher RP. Behind the wheel and under the hood: functions of cyclin-dependent kinases in response to DNA damage. DNA Repair (Amst). 2009 Sep 2; 8(9):1018-24.
      View in: PubMed
    16. Park EJ, Kong D, Fisher R, Cardellina J, Shoemaker RH, Melillo G. Targeting the PAS-A domain of HIF-1alpha for development of small molecule inhibitors of HIF-1. Cell Cycle. 2006 Aug; 5(16):1847-53.
      View in: PubMed
    17. Liu Y, Graham C, Li A, Fisher RJ, Shaw S. Phosphorylation of the protein kinase C-theta activation loop and hydrophobic motif regulates its kinase activity, but only activation loop phosphorylation is critical to in vivo nuclear-factor-kappaB induction. Biochem J. 2002 Jan 15; 361(Pt 2):255-65.
      View in: PubMed
    18. Chatterjee TK, Fisher RA. Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs. J Biol Chem. 2000 Aug 4; 275(31):24013-21.
      View in: PubMed
    19. Soteriou B, Fisher RA, Khan IM, Kessling AM, Archard LC, Buluwela L. Conserved gene sequences for species identification: PCR analysis of the 3' UTR of the SON gene distinguishes human and other mammalian DNAs. Forensic Sci Int. 1995 Jun 21; 73(3):171-81.
      View in: PubMed
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067