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Last Name
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Konstantina Alexandropoulos

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentClinical Immunology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Bonito AJ, Aloman C, Fiel MI, Danzl NM, Cha S, Weinstein EG, Jeong S, Choi Y, Walsh MC, Alexandropoulos K. Medullary thymic epithelial cell depletion leads to autoimmune hepatitis. J Clin Invest. 2013 Aug 1; 123(8):3510-24.
      View in: PubMed
    2. Alexandropoulos K, Danzl NM. Thymic epithelial cells: antigen presenting cells that regulate T cell repertoire and tolerance development. Immunol Res. 2012 Dec; 54(1-3):177-90.
      View in: PubMed
    3. Danzl NM, Donlin LT, Alexandropoulos K. Regulation of medullary thymic epithelial cell differentiation and function by the signaling protein Sin. J Exp Med. 2010 May 10; 207(5):999-1013.
      View in: PubMed
    4. Alexandropoulos K, Regelmann AG. Regulation of T-lymphocyte physiology by the Chat-H/CasL adapter complex. Immunol Rev. 2009 Nov; 232(1):160-74.
      View in: PubMed
    5. Regelmann AG, Danzl NM, Wanjalla C, Alexandropoulos K. The hematopoietic isoform of Cas-Hef1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking. Immunity. 2006 Dec; 25(6):907-18.
      View in: PubMed
    6. Natarajan M, Stewart JE, Golemis EA, Pugacheva EN, Alexandropoulos K, Cox BD, Wang W, Grammer JR, Gladson CL. HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells. Oncogene. 2006 Mar 16; 25(12):1721-32.
      View in: PubMed
    7. Donlin LT, Danzl NM, Wanjalla C, Alexandropoulos K. Deficiency in expression of the signaling protein Sin/Efs leads to T-lymphocyte activation and mucosal inflammation. Mol Cell Biol. 2005 Dec; 25(24):11035-46.
      View in: PubMed
    8. Xing L, Donlin LT, Miller RH, Alexandropoulos K. The adapter molecule Sin regulates T-cell-receptor-mediated signal transduction by modulating signaling substrate availability. Mol Cell Biol. 2004 May; 24(10):4581-92.
      View in: PubMed
    9. Alexandropoulos K, Donlin LT, Xing L, Regelmann AG. Sin: good or bad? A T lymphocyte perspective. Immunol Rev. 2003 Apr; 192:181-95.
      View in: PubMed
    10. Donlin LT, Roman CA, Adlam M, Regelmann AG, Alexandropoulos K. Defective thymocyte maturation by transgenic expression of a truncated form of the T lymphocyte adapter molecule and Fyn substrate, Sin. J Immunol. 2002 Dec 15; 169(12):6900-9.
      View in: PubMed
    11. Yang LT, Alexandropoulos K, Sap J. c-SRC mediates neurite outgrowth through recruitment of Crk to the scaffolding protein Sin/Efs without altering the kinetics of ERK activation. J Biol Chem. 2002 May 17; 277(20):17406-14.
      View in: PubMed
    12. Xing L, Ge C, Zeltser R, Maskevitch G, Mayer BJ, Alexandropoulos K. c-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase. Mol Cell Biol. 2000 Oct; 20(19):7363-77.
      View in: PubMed
    13. Alexandropoulos K, Baltimore D. Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin. Genes Dev. 1996 Jun 1; 10(11):1341-55.
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    14. Baltimore D, Ren R, Cheng G, Alexandropoulos K, Cicchetti P. A nuclear tyrosine kinase becomes a cytoplasmic oncogene. Ann N Y Acad Sci. 1995 Jun 30; 758:339-44.
      View in: PubMed
    15. Alexandropoulos K, Cheng G, Baltimore D. Proline-rich sequences that bind to Src homology 3 domains with individual specificities. Proc Natl Acad Sci U S A. 1995 Apr 11; 92(8):3110-4.
      View in: PubMed
    16. Jiang H, Alexandropoulos K, Song J, Foster DA. Evidence that v-Src-induced phospholipase D activity is mediated by a G protein. Mol Cell Biol. 1994 Jun; 14(6):3676-82.
      View in: PubMed
    17. Alexandropoulos K, Qureshi SA, Foster DA. Ha-Ras functions downstream from protein kinase C in v-Fps-induced gene expression mediated by TPA response elements. Oncogene. 1993 Mar; 8(3):803-7.
      View in: PubMed
    18. Alexandropoulos K, Qureshi SA, Bruder JT, Rapp U, Foster DA. The induction of Egr-1 expression by v-Fps is via a protein kinase C-independent intracellular signal that is sequentially dependent upon HaRas and Raf-1. Cell Growth Differ. 1992 Oct; 3(10):731-7.
      View in: PubMed
    19. Qureshi SA, Alexandropoulos K, Rim M, Joseph CK, Bruder JT, Rapp UR, Foster DA. Evidence that Ha-Ras mediates two distinguishable intracellular signals activated by v-Src. J Biol Chem. 1992 Sep 5; 267(25):17635-9.
      View in: PubMed
    20. Alexandropoulos K, Qureshi SA, Rim M, Sukhatme VP, Foster DA. v-Fps-responsiveness in the Egr-1 promoter is mediated by serum response elements. Nucleic Acids Res. 1992 May 11; 20(9):2355-9.
      View in: PubMed
    21. Qureshi SA, Rim MH, Alexandropoulos K, Berg K, Sukhatme VP, Foster DA. Sustained induction of egr-1 by v-src correlates with a lack of fos-mediated repression of the egr-1 promoter. Oncogene. 1992 Jan; 7(1):121-5.
      View in: PubMed
    22. Alexandropoulos K, Joseph CK, Spangler R, Foster DA. Evidence that a G-protein transduces signals initiated by the protein-tyrosine kinase v-Fps. J Biol Chem. 1991 Aug 25; 266(24):15583-6.
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    23. Qureshi SA, Alexandropoulos K, Joseph CK, Spangler R, Foster DA. Cholera toxin induces expression of the immediate-early response gene JE via a cyclic AMP-independent signaling pathway. Mol Cell Biol. 1991 Jan; 11(1):102-7.
      View in: PubMed
    24. Dauphinais ID, DeLisi LE, Crow TJ, Alexandropoulos K, Colter N, Tuma I, Gershon ES. Reduction in temporal lobe size in siblings with schizophrenia: a magnetic resonance imaging study. Psychiatry Res. 1990 Dec; 35(2):137-47.
      View in: PubMed
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