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Last Name
Institution

Philippe M. Soriano

TitlePROFESSOR
InstitutionMount Sinai
DepartmentDevelopmental and Regenerative Biology
Address
    Other Positions
    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentOncological Sciences


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. He F, Soriano P. A critical role for PDGFRa signaling in medial nasal process development. PLoS Genet. 2013; 9(9):e1003851.
      View in: PubMed
    2. Friedel RH, Friedel CC, Bonfert T, Shi R, Rad R, Soriano P. Clonal expansion analysis of transposon insertions by high-throughput sequencing identifies candidate cancer genes in a PiggyBac mutagenesis screen. PLoS One. 2013; 8(8):e72338.
      View in: PubMed
    3. Lewis AE, Vasudevan HN, O'Neill AK, Soriano P, Bush JO. The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Dev Biol. 2013 Jul 15; 379(2):229-34.
      View in: PubMed
    4. Olson LE, Soriano P. PDGFRß signaling regulates mural cell plasticity and inhibits fat development. Dev Cell. 2011 Jun 14; 20(6):815-26.
      View in: PubMed
    5. Raymond CS, Soriano P. ROSA26Flpo deleter mice promote efficient inversion of conditional gene traps in vivo. Genesis. 2010 Oct 1; 48(10):603-6.
      View in: PubMed
    6. Bush JO, Soriano P. Ephrin-B1 forward signaling regulates craniofacial morphogenesis by controlling cell proliferation across Eph-ephrin boundaries. Genes Dev. 2010 Sep 15; 24(18):2068-80.
      View in: PubMed
    7. Friedel RH, Soriano P. Gene trap mutagenesis in the mouse. Methods Enzymol. 2010; 477:243-69.
      View in: PubMed
    8. Wassarman PM, Soriano PM. Guide to techniques in mouse development. Preface. Methods Enzymol. 2010; 476:xix.
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    9. Wassarman PM, Soriano PM. Technological advances in mouse development studies. Preface. Methods Enzymol. 2010; 477:xix.
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    10. Bush JO, Soriano P. Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1; 23(13):1586-99.
      View in: PubMed
    11. Olson LE, Soriano P. Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev Cell. 2009 Feb; 16(2):303-13.
      View in: PubMed
    12. Schmahl J, Rizzolo K, Soriano P. The PDGF signaling pathway controls multiple steroid-producing lineages. Genes Dev. 2008 Dec 1; 22(23):3255-67.
      View in: PubMed
    13. Raymond CS, Soriano P. High-efficiency FLP and PhiC31 site-specific recombination in mammalian cells. PLoS One. 2007; 2(1):e162.
      View in: PubMed
    14. Davy A, Soriano P. Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development. Dev Biol. 2007 Apr 1; 304(1):182-93.
      View in: PubMed
    15. Schmahl J, Raymond CS, Soriano P. PDGF signaling specificity is mediated through multiple immediate early genes. Nat Genet. 2007 Jan; 39(1):52-60.
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    16. Raymond CS, Soriano P. Engineering mutations: deconstructing the mouse gene by gene. Dev Dyn. 2006 Sep; 235(9):2424-36.
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    17. Hoch RV, Soriano P. Context-specific requirements for Fgfr1 signaling through Frs2 and Frs3 during mouse development. Development. 2006 Feb; 133(4):663-73.
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    18. Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, Hicks GG, Huang CC, Johns SJ, Kawamoto M, Liu S, Meng EC, Morris JH, Rossant J, Ruiz P, Skarnes WC, Soriano P, Stanford WL, Stryke D, von Melchner H, Wurst W, Yamamura K, Young SG, Babbitt PC, Ferrin TE. The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Res. 2006 Jan 1; 34(Database issue):D642-8.
      View in: PubMed
    19. Xu X, Bringas P, Soriano P, Chai Y. PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis. Dev Dyn. 2005 Jan; 232(1):75-84.
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    20. Ding H, Wu X, Boström H, Kim I, Wong N, Tsoi B, O'Rourke M, Koh GY, Soriano P, Betsholtz C, Hart TC, Marazita ML, Field LL, Tam PP, Nagy A. A specific requirement for PDGF-C in palate formation and PDGFR-alpha signaling. Nat Genet. 2004 Oct; 36(10):1111-6.
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    21. Aubin J, Davy A, Soriano P. In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis. Genes Dev. 2004 Jun 15; 18(12):1482-94.
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    22. Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, Cox T, Young SG, Ruiz P, Soriano P, Tessier-Lavigne M, Conklin BR, Stanford WL, Rossant J. A public gene trap resource for mouse functional genomics. Nat Genet. 2004 Jun; 36(6):543-4.
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    23. Davy A, Aubin J, Soriano P. Ephrin-B1 forward and reverse signaling are required during mouse development. Genes Dev. 2004 Mar 1; 18(5):572-83.
      View in: PubMed
    24. Chen WV, Delrow J, Corrin PD, Frazier JP, Soriano P. Identification and validation of PDGF transcriptional targets by microarray-coupled gene-trap mutagenesis. Nat Genet. 2004 Mar; 36(3):304-12.
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    25. Tallquist MD, French WJ, Soriano P. Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development. PLoS Biol. 2003 Nov; 1(2):E52.
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    26. Awatramani R, Soriano P, Rodriguez C, Mai JJ, Dymecki SM. Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat Genet. 2003 Sep; 35(1):70-5.
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    27. Hamilton TG, Klinghoffer RA, Corrin PD, Soriano P. Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. Mol Cell Biol. 2003 Jun; 23(11):4013-25.
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    28. Tallquist MD, Soriano P. Cell autonomous requirement for PDGFRalpha in populations of cranial and cardiac neural crest cells. Development. 2003 Feb; 130(3):507-18.
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    29. Chen WV, Soriano P. Gene trap mutagenesis in embryonic stem cells. Methods Enzymol. 2003; 365:367-86.
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    30. Komada M, Soriano P. [Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier. J Cell Biol. 2002 Jan 21; 156(2):337-48.
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    31. Klinghoffer RA, Hamilton TG, Hoch R, Soriano P. An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development. Dev Cell. 2002 Jan; 2(1):103-13.
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    32. Awatramani R, Soriano P, Mai JJ, Dymecki S. An Flp indicator mouse expressing alkaline phosphatase from the ROSA26 locus. Nat Genet. 2001 Nov; 29(3):257-9.
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    33. Medico E, Gambarotta G, Gentile A, Comoglio PM, Soriano P. A gene trap vector system for identifying transcriptionally responsive genes. Nat Biotechnol. 2001 Jun; 19(6):579-82.
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    34. Klinghoffer RA, Mueting-Nelsen PF, Faerman A, Shani M, Soriano P. The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions. Mol Cell. 2001 Feb; 7(2):343-54.
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    35. Tallquist MD, Klinghoffer RA, Heuchel R, Mueting-Nelsen PF, Corrin PD, Heldin CH, Johnson RJ, Soriano P. Retention of PDGFR-beta function in mice in the absence of phosphatidylinositol 3'-kinase and phospholipase Cgamma signaling pathways. Genes Dev. 2000 Dec 15; 14(24):3179-90.
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    36. Farley FW, Soriano P, Steffen LS, Dymecki SM. Widespread recombinase expression using FLPeR (flipper) mice. Genesis. 2000 Nov-Dec; 28(3-4):106-10.
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    37. Komada M, McLean DJ, Griswold MD, Russell LD, Soriano P. E-MAP-115, encoding a microtubule-associated protein, is a retinoic acid-inducible gene required for spermatogenesis. Genes Dev. 2000 Jun 1; 14(11):1332-42.
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    38. Jiang X, Rowitch DH, Soriano P, McMahon AP, Sucov HM. Fate of the mammalian cardiac neural crest. Development. 2000 Apr; 127(8):1607-16.
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    39. Tallquist MD, Soriano P. Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. Genesis. 2000 Feb; 26(2):113-5.
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    40. Andrews A, Balciunaite E, Leong FL, Tallquist M, Soriano P, Refojo M, Kazlauskas A. Platelet-derived growth factor plays a key role in proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci. 1999 Oct; 40(11):2683-9.
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    41. Heuchel R, Berg A, Tallquist M, Ahlén K, Reed RK, Rubin K, Claesson-Welsh L, Heldin CH, Soriano P. Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling. Proc Natl Acad Sci U S A. 1999 Sep 28; 96(20):11410-5.
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    42. Ohlsson R, Falck P, Hellström M, Lindahl P, Boström H, Franklin G, Ahrlund-Richter L, Pollard J, Soriano P, Betsholtz C. PDGFB regulates the development of the labyrinthine layer of the mouse fetal placenta. Dev Biol. 1999 Aug 1; 212(1):124-36.
      View in: PubMed
    43. Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 1999 Jan; 21(1):70-1.
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    44. Lindahl P, Hellström M, Kalén M, Karlsson L, Pekny M, Pekna M, Soriano P, Betsholtz C. Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli. Development. 1998 Sep; 125(17):3313-22.
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    45. Crosby JR, Seifert RA, Soriano P, Bowen-Pope DF. Chimaeric analysis reveals role of Pdgf receptors in all muscle lineages. Nat Genet. 1998 Apr; 18(4):385-8.
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    46. Foley KP, McArthur GA, Quéva C, Hurlin PJ, Soriano P, Eisenman RN. Targeted disruption of the MYC antagonist MAD1 inhibits cell cycle exit during granulocyte differentiation. EMBO J. 1998 Feb 2; 17(3):774-85.
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    47. Friedrich GA, Hildebrand JD, Soriano P. The secretory protein Sec8 is required for paraxial mesoderm formation in the mouse. Dev Biol. 1997 Dec 15; 192(2):364-74.
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    48. Zambrowicz BP, Imamoto A, Fiering S, Herzenberg LA, Kerr WG, Soriano P. Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A. 1997 Apr 15; 94(8):3789-94.
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    49. Chen Z, Friedrich GA, Soriano P. Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes Dev. 1994 Oct 1; 8(19):2293-301.
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    50. Grompe M, al-Dhalimy M, Finegold M, Ou CN, Burlingame T, Kennaway NG, Soriano P. Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice. Genes Dev. 1993 Dec; 7(12A):2298-307.
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    51. Imamoto A, Soriano P. Disruption of the csk gene, encoding a negative regulator of Src family tyrosine kinases, leads to neural tube defects and embryonic lethality in mice. Cell. 1993 Jun 18; 73(6):1117-24.
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    52. Friedrich G, Soriano P. Insertional mutagenesis by retroviruses and promoter traps in embryonic stem cells. Methods Enzymol. 1993; 225:681-701.
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    53. Friedrich G, Soriano P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev. 1991 Sep; 5(9):1513-23.
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    54. Soriano P, Montgomery C, Geske R, Bradley A. Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice. Cell. 1991 Feb 22; 64(4):693-702.
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    55. Harbers K, Francke U, Soriano P, Jaenisch R, Müller U. Structure and chromosomal mapping of a highly polymorphic repetitive DNA sequence from the pseudoautosomal region of the mouse sex chromosomes. Cytogenet Cell Genet. 1990; 53(2-3):129-33.
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    56. Soriano P, Gridley T, Jaenisch R. Retroviruses and insertional mutagenesis in mice: proviral integration at the Mov 34 locus leads to early embryonic death. Genes Dev. 1987 Jun; 1(4):366-75.
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    57. Soriano P, Dijkstra J, Legrand A, Spanjer H, Londos-Gagliardi D, Roerdink F, Scherphof G, Nicolau C. Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene. Proc Natl Acad Sci U S A. 1983 Dec; 80(23):7128-31.
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067