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Benjamin R. tenOever

TitlePROFESSOR
InstitutionMount Sinai
DepartmentMicrobiology
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     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Schmid S, Sachs D, Tenoever BR. Mitogen-activated Protein Kinase-mediated Licensing of Interferon Regulatory Factor 3/7 Reinforces the Cell Response to Virus. J Biol Chem. 2014 Jan 3; 289(1):299-311.
      View in: PubMed
    2. Cullen BR, Cherry S, tenOever BR. Is RNA interference a physiologically relevant innate antiviral immune response in mammals? Cell Host Microbe. 2013 Oct 16; 14(4):374-8.
      View in: PubMed
    3. Varble A, Benitez AA, Schmid S, Sachs D, Shim JV, Rodriguez-Barrueco R, Panis M, Crumiller M, Silva JM, Sachidanandam R, tenOever BR. An in vivo RNAi screening approach to identify host determinants of virus replication. Cell Host Microbe. 2013 Sep 11; 14(3):346-56.
      View in: PubMed
    4. Langlois RA, Albrecht RA, Kimble B, Sutton T, Shapiro JS, Finch C, Angel M, Chua MA, Gonzalez-Reiche AS, Xu K, Perez D, García-Sastre A, tenOever BR. MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies. Nat Biotechnol. 2013 Sep; 31(9):844-7.
      View in: PubMed
    5. tenOever BR. RNA viruses and the host microRNA machinery. Nat Rev Microbiol. 2013 Mar; 11(3):169-80.
      View in: PubMed
    6. Chua MA, Schmid S, Perez JT, Langlois RA, Tenoever BR. Influenza A virus utilizes suboptimal splicing to coordinate the timing of infection. Cell Rep. 2013 Jan 31; 3(1):23-9.
      View in: PubMed
    7. Perez JT, Zlatev I, Aggarwal S, Subramanian S, Sachidanandam R, Kim B, Manoharan M, tenOever BR. A small-RNA enhancer of viral polymerase activity. J Virol. 2012 Dec; 86(24):13475-85.
      View in: PubMed
    8. Backes S, Shapiro JS, Sabin LR, Pham AM, Reyes I, Moss B, Cherry S, tenOever BR. Degradation of host microRNAs by poxvirus poly(A) polymerase reveals terminal RNA methylation as a protective antiviral mechanism. Cell Host Microbe. 2012 Aug 16; 12(2):200-10.
      View in: PubMed
    9. Langlois RA, Varble A, Chua MA, García-Sastre A, tenOever BR. Hematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responses. Proc Natl Acad Sci U S A. 2012 Jul 24; 109(30):12117-22.
      View in: PubMed
    10. Shapiro JS, Langlois RA, Pham AM, Tenoever BR. Evidence for a cytoplasmic microprocessor of pri-miRNAs. RNA. 2012 Jul; 18(7):1338-46.
      View in: PubMed
    11. Pham AM, Langlois RA, TenOever BR. Replication in cells of hematopoietic origin is necessary for Dengue virus dissemination. PLoS Pathog. 2012 Jan; 8(1):e1002465.
      View in: PubMed
    12. Ng SL, Friedman BA, Schmid S, Gertz J, Myers RM, Tenoever BR, Maniatis T. I?B kinase epsilon (IKK(epsilon)) regulates the balance between type I and type II interferon responses. Proc Natl Acad Sci U S A. 2011 Dec 27; 108(52):21170-5.
      View in: PubMed
    13. Langlois RA, Shapiro JS, Pham AM, tenOever BR. In vivo delivery of cytoplasmic RNA virus-derived miRNAs. Mol Ther. 2012 Feb; 20(2):367-75.
      View in: PubMed
    14. Schmid S, Mordstein M, Kochs G, García-Sastre A, Tenoever BR. Transcription factor redundancy ensures induction of the antiviral state. J Biol Chem. 2010 Dec 31; 285(53):42013-22.
      View in: PubMed
    15. Shapiro JS, Varble A, Pham AM, Tenoever BR. Noncanonical cytoplasmic processing of viral microRNAs. RNA. 2010 Nov; 16(11):2068-74.
      View in: PubMed
    16. Varble A, Chua MA, Perez JT, Manicassamy B, García-Sastre A, tenOever BR. Engineered RNA viral synthesis of microRNAs. Proc Natl Acad Sci U S A. 2010 Jun 22; 107(25):11519-24.
      View in: PubMed
    17. Perez JT, Varble A, Sachidanandam R, Zlatev I, Manoharan M, García-Sastre A, tenOever BR. Influenza A virus-generated small RNAs regulate the switch from transcription to replication. Proc Natl Acad Sci U S A. 2010 Jun 22; 107(25):11525-30.
      View in: PubMed
    18. Zaslavsky E, Hershberg U, Seto J, Pham AM, Marquez S, Duke JL, Wetmur JG, Tenoever BR, Sealfon SC, Kleinstein SH. Antiviral response dictated by choreographed cascade of transcription factors. J Immunol. 2010 Mar 15; 184(6):2908-17.
      View in: PubMed
    19. Pham AM, Tenoever BR. The IKK Kinases: Operators of Antiviral Signaling. Viruses. 2010 Jan; 2(1):55-72.
      View in: PubMed
    20. Tenoever B. MicroManipulating viral-based therapeutics. Discov Med. 2009 Aug; 8(41):51-4.
      View in: PubMed
    21. Perez JT, Pham AM, Lorini MH, Chua MA, Steel J, tenOever BR. MicroRNA-mediated species-specific attenuation of influenza A virus. Nat Biotechnol. 2009 Jun; 27(6):572-6.
      View in: PubMed
    22. Tenoever BR, Ng SL, Chua MA, McWhirter SM, García-Sastre A, Maniatis T. Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science. 2007 Mar 2; 315(5816):1274-8.
      View in: PubMed
    23. Tenoever BR, Maniatis T. Parallel pathways of virus recognition. Immunity. 2006 May; 24(5):510-2.
      View in: PubMed
    24. McWhirter SM, Tenoever BR, Maniatis T. Connecting mitochondria and innate immunity. Cell. 2005 Sep 9; 122(5):645-7.
      View in: PubMed
    25. Grandvaux N, Gaboriau F, Harris J, tenOever BR, Lin R, Hiscott J. Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response. FEBS J. 2005 Jun; 272(12):3120-31.
      View in: PubMed
    26. tenOever BR, Sharma S, Zou W, Sun Q, Grandvaux N, Julkunen I, Hemmi H, Yamamoto M, Akira S, Yeh WC, Lin R, Hiscott J. Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunity. J Virol. 2004 Oct; 78(19):10636-49.
      View in: PubMed
    27. Sgarbanti M, Arguello M, tenOever BR, Battistini A, Lin R, Hiscott J. A requirement for NF-kappaB induction in the production of replication-competent HHV-8 virions. Oncogene. 2004 Jul 29; 23(34):5770-80.
      View in: PubMed
    28. Miller K, McArdle S, Gale MJ, Geller DA, Tenoever B, Hiscott J, Gretch DR, Polyak SJ. Effects of the hepatitis C virus core protein on innate cellular defense pathways. J Interferon Cytokine Res. 2004 Jul; 24(7):391-402.
      View in: PubMed
    29. Hiscott J, Grandvaux N, Sharma S, Tenoever BR, Servant MJ, Lin R. Convergence of the NF-kappaB and interferon signaling pathways in the regulation of antiviral defense and apoptosis. Ann N Y Acad Sci. 2003 Dec; 1010:237-48.
      View in: PubMed
    30. Stojdl DF, Lichty BD, tenOever BR, Paterson JM, Power AT, Knowles S, Marius R, Reynard J, Poliquin L, Atkins H, Brown EG, Durbin RK, Durbin JE, Hiscott J, Bell JC. VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents. Cancer Cell. 2003 Oct; 4(4):263-75.
      View in: PubMed
    31. Sharma S, tenOever BR, Grandvaux N, Zhou GP, Lin R, Hiscott J. Triggering the interferon antiviral response through an IKK-related pathway. Science. 2003 May 16; 300(5622):1148-51.
      View in: PubMed
    32. Servant MJ, Grandvaux N, tenOever BR, Duguay D, Lin R, Hiscott J. Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA. J Biol Chem. 2003 Mar 14; 278(11):9441-7.
      View in: PubMed
    33. Slack A, Bovenzi V, Bigey P, Ivanov MA, Ramchandani S, Bhattacharya S, tenOever B, Lamrihi B, Scherman D, Szyf M. Antisense MBD2 gene therapy inhibits tumorigenesis. J Gene Med. 2002 Jul-Aug; 4(4):381-9.
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    34. Grandvaux N, Servant MJ, tenOever B, Sen GC, Balachandran S, Barber GN, Lin R, Hiscott J. Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes. J Virol. 2002 Jun; 76(11):5532-9.
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    35. Grandvaux N, tenOever BR, Servant MJ, Hiscott J. The interferon antiviral response: from viral invasion to evasion. Curr Opin Infect Dis. 2002 Jun; 15(3):259-67.
      View in: PubMed
    36. tenOever BR, Servant MJ, Grandvaux N, Lin R, Hiscott J. Recognition of the measles virus nucleocapsid as a mechanism of IRF-3 activation. J Virol. 2002 Apr; 76(8):3659-69.
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    37. Servant MJ, Tenoever B, Lin R. Overlapping and distinct mechanisms regulating IRF-3 and IRF-7 function. J Interferon Cytokine Res. 2002 Jan; 22(1):49-58.
      View in: PubMed
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