Keywords
Last Name
Institution

Michelle Ehrlich

TitlePROFESSOR
InstitutionMount Sinai
DepartmentNeurology
Address
    Other Positions
    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentNeurology

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentGenetics and Genomic Sciences


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Unterwald EM, Page ME, Brown TB, Miller JS, Ruiz M, Pescatore KA, Xu B, Reichardt LF, Beverley J, Tang B, Steiner H, Thomas EA, Ehrlich ME. Behavioral and transcriptome alterations in male and female mice with postnatal deletion of TrkB in dorsal striatal medium spiny neurons. Mol Neurodegener. 2013; 8(1):47.
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    2. Chandwani S, Keilani S, Ortiz-Virumbrales M, Morant A, Bezdecny S, Ehrlich ME. Induction of DARPP-32 by Brain-Derived Neurotrophic Factor in Striatal Neurons In Vitro Is Modified by Histone Deacetylase Inhibitors and Nab2. PLoS One. 2013; 8(10):e76842.
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    3. Kim HA, Jiang L, Madsen H, Parish CL, Massalas J, Smardencas A, O'Leary C, Gantois I, O'Tuathaigh C, Waddington JL, Ehrlich ME, Lawrence AJ, Drago J. Resolving pathobiological mechanisms relating to Huntington disease: Gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cells. Neurobiol Dis. 2014 Feb; 62:323-37.
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    4. Smardencas A, Rizkalla K, Kim HA, Massalas J, O'Leary C, Ehrlich ME, Schütz G, Lawrence AJ, Drago J. Phenotyping dividing cells in mouse models of neurodegenerative basal ganglia diseases. BMC Neurosci. 2013; 14:111.
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    5. Zhu L, Zhong M, Zhao J, Rhee H, Caesar I, Knight EM, Volpicelli-Daley L, Bustos V, Netzer W, Liu L, Lucast L, Ehrlich ME, Robakis NK, Gandy SE, Cai D. Reduction of synaptojanin 1 accelerates aß clearance and attenuates cognitive deterioration in an Alzheimer mouse model. J Biol Chem. 2013 Nov 1; 288(44):32050-63.
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    6. Lane RF, Steele JW, Cai D, Ehrlich ME, Attie AD, Gandy S. Protein sorting motifs in the cytoplasmic tail of SorCS1 control generation of Alzheimer's amyloid-ß peptide. J Neurosci. 2013 Apr 17; 33(16):7099-107.
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    7. Fuchs T, Saunders-Pullman R, Masuho I, Luciano MS, Raymond D, Factor S, Lang AE, Liang TW, Trosch RM, White S, Ainehsazan E, Hervé D, Sharma N, Ehrlich ME, Martemyanov KA, Bressman SB, Ozelius LJ. Mutations in GNAL cause primary torsion dystonia. Nat Genet. 2013 Jan; 45(1):88-92.
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    8. Kovalenko M, Dragileva E, St Claire J, Gillis T, Guide JR, New J, Dong H, Kucherlapati R, Kucherlapati MH, Ehrlich ME, Lee JM, Wheeler VC. Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice. PLoS One. 2012; 7(9):e44273.
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    9. Steele JW, Ju S, Lachenmayer ML, Liken J, Stock A, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Protter AA, Martins RN, Ehrlich ME, Yue Z, Petsko GA, Gandy S. Latrepirdine stimulates autophagy and reduces accumulation of a-synuclein in cells and in mouse brain. Mol Psychiatry. 2013 Aug; 18(8):882-8.
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    10. Steele JW, Lachenmayer ML, Ju S, Stock A, Liken J, Kim SH, Delgado LM, Alfaro IE, Bernales S, Verdile G, Bharadwaj P, Gupta V, Barr R, Friss A, Dolios G, Wang R, Ringe D, Fraser P, Westaway D, St George-Hyslop PH, Szabo P, Relkin NR, Buxbaum JD, Glabe CG, Protter AA, Martins RN, Ehrlich ME, Petsko GA, Yue Z, Gandy S. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Mol Psychiatry. 2013 Aug; 18(8):889-97.
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    11. Hager S, Lösch S, Noll S, Khan-Vaughan L, Ehrlich ME, Kranz H. Red/ET recombination with chimeric oligonucleotides allows rapid generation of BAC transgenes harboring full-length or truncated huntingtin cDNA. Biotechniques. 2012; 2012.
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    12. Keilani S, Chandwani S, Dolios G, Bogush A, Beck H, Hatzopoulos AK, Rao GN, Thomas EA, Wang R, Ehrlich ME. Egr-1 induces DARPP-32 expression in striatal medium spiny neurons via a conserved intragenic element. J Neurosci. 2012 May 16; 32(20):6808-18.
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    13. Ehrlich ME. Huntington's disease and the striatal medium spiny neuron: cell-autonomous and non-cell-autonomous mechanisms of disease. Neurotherapeutics. 2012 Apr; 9(2):270-84.
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    14. Bharadwaj PR, Verdile G, Barr RK, Gupta V, Steele JW, Lachenmayer ML, Yue Z, Ehrlich ME, Petsko G, Ju S, Ringe D, Sankovich SE, Caine JM, Macreadie IG, Gandy S, Martins RN. Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aß42 levels in yeast. J Alzheimers Dis. 2012; 32(4):949-67.
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    15. Ehrlich ME, Gandy S. Chromatin plasticity and the pathogenesis of Huntington disease. Proc Natl Acad Sci U S A. 2011 Oct 11; 108(41):16867-8.
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    16. Madsen HB, Navaratnarajah S, Farrugia J, Djouma E, Ehrlich M, Mantamadiotis T, Van Deursen J, Lawrence AJ. CREB1 and CREB-binding protein in striatal medium spiny neurons regulate behavioural responses to psychostimulants. Psychopharmacology (Berl). 2012 Feb; 219(3):699-713.
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    17. Kim SH, Thomas CA, André VM, Cummings DM, Cepeda C, Levine MS, Ehrlich ME. Forebrain striatal-specific expression of mutant huntingtin protein in vivo induces cell-autonomous age-dependent alterations in sensitivity to excitotoxicity and mitochondrial function. ASN Neuro. 2011; 3(3):e00060.
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    18. Tomiyama K, Kim HA, Kinsella A, Ehrlich ME, Schütz G, Koshikawa N, Lawrence AJ, Waddington JL, Drago J. Phenotypic disruption to orofacial movement topography in conditional mutants with generalized CamKIIa/Cre D1Tox versus striatal-specific DARPP-32/Cre D1Tox ablation of D1 dopamine receptor-expressing cells. Synapse. 2011 Sep; 65(9):835-42.
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    19. Martin JN, Wolken N, Brown T, Dauer WT, Ehrlich ME, Gonzalez-Alegre P. Lethal toxicity caused by expression of shRNA in the mouse striatum: implications for therapeutic design. Gene Ther. 2011 Jul; 18(7):666-73.
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    20. Lane RF, Gatson JW, Small SA, Ehrlich ME, Gandy S. Protein kinase C and rho activated coiled coil protein kinase 2 (ROCK2) modulate Alzheimer's APP metabolism and phosphorylation of the Vps10-domain protein, SorL1. Mol Neurodegener. 2010; 5:62.
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    21. Thomas EA, Coppola G, Tang B, Kuhn A, Kim S, Geschwind DH, Brown TB, Luthi-Carter R, Ehrlich ME. In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons. Hum Mol Genet. 2011 Mar 15; 20(6):1049-60.
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    22. Kraft WK, Dysart K, Greenspan JS, Gibson E, Kaltenbach K, Ehrlich ME. Revised dose schema of sublingual buprenorphine in the treatment of the neonatal opioid abstinence syndrome. Addiction. 2011 Mar; 106(3):574-80.
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    23. Gavarini S, Cayrol C, Fuchs T, Lyons N, Ehrlich ME, Girard JP, Ozelius LJ. Direct interaction between causative genes of DYT1 and DYT6 primary dystonia. Ann Neurol. 2010 Oct; 68(4):549-53.
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    24. Lane RF, Raines SM, Steele JW, Ehrlich ME, Lah JA, Small SA, Tanzi RE, Attie AD, Gandy S. Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex. J Neurosci. 2010 Sep 29; 30(39):13110-5.
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    25. Gandy S, Simon AJ, Steele JW, Lublin AL, Lah JJ, Walker LC, Levey AI, Krafft GA, Levy E, Checler F, Glabe C, Bilker WB, Abel T, Schmeidler J, Ehrlich ME. Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers. Ann Neurol. 2010 Aug; 68(2):220-30.
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    26. Page ME, Bao L, Andre P, Pelta-Heller J, Sluzas E, Gonzalez-Alegre P, Bogush A, Khan LE, Iacovitti L, Rice ME, Ehrlich ME. Cell-autonomous alteration of dopaminergic transmission by wild type and mutant (DeltaE) TorsinA in transgenic mice. Neurobiol Dis. 2010 Sep; 39(3):318-26.
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    27. Kim SH, Fraser PE, Westaway D, St George-Hyslop PH, Ehrlich ME, Gandy S. Group II metabotropic glutamate receptor stimulation triggers production and release of Alzheimer's amyloid(beta)42 from isolated intact nerve terminals. J Neurosci. 2010 Mar 17; 30(11):3870-5.
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    28. Kajiwara Y, Franciosi S, Takahashi N, Krug L, Schmeidler J, Taddei K, Haroutunian V, Fried U, Ehrlich M, Martins RN, Gandy S, Buxbaum JD. Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease. Mol Neurodegener. 2010; 5:1.
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    29. Steele JW, Kim SH, Cirrito JR, Verges DK, Restivo JL, Westaway D, Fraser P, Hyslop PS, Sano M, Bezprozvanny I, Ehrlich ME, Holtzman DM, Gandy S. Acute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivo. Mol Neurodegener. 2009; 4:51.
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    30. Pedrini S, Thomas C, Brautigam H, Schmeidler J, Ho L, Fraser P, Westaway D, Hyslop PS, Martins RN, Buxbaum JD, Pasinetti GM, Dickstein DL, Hof PR, Ehrlich ME, Gandy S. Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology. Mol Neurodegener. 2009; 4:40.
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    31. Fuchs T, Gavarini S, Saunders-Pullman R, Raymond D, Ehrlich ME, Bressman SB, Ozelius LJ. Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia. Nat Genet. 2009 Mar; 41(3):286-8.
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    32. Kraft WK, Gibson E, Dysart K, Damle VS, Larusso JL, Greenspan JS, Moody DE, Kaltenbach K, Ehrlich ME. Sublingual buprenorphine for treatment of neonatal abstinence syndrome: a randomized trial. Pediatrics. 2008 Sep; 122(3):e601-7.
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    33. Brown TB, Bogush AI, Ehrlich ME. Neocortical expression of mutant huntingtin is not required for alterations in striatal gene expression or motor dysfunction in a transgenic mouse. Hum Mol Genet. 2008 Oct 15; 17(20):3095-104.
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    34. Pedrini S, Bogush A, Ehrlich ME. Phosphatidylinositide 3-kinase and protein kinase C zeta mediate retinoic acid induction of DARPP-32 in medium size spiny neurons in vitro. J Neurochem. 2008 Jul; 106(2):917-24.
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    35. Tropea TF, Guerriero RM, Willuhn I, Unterwald EM, Ehrlich ME, Steiner H, Kosofsky BE. Augmented D1 dopamine receptor signaling and immediate-early gene induction in adult striatum after prenatal cocaine. Biol Psychiatry. 2008 Jun 1; 63(11):1066-74.
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    36. Niculescu M, Perrine SA, Miller JS, Ehrlich ME, Unterwald EM. Trk: a neuromodulator of age-specific behavioral and neurochemical responses to cocaine in mice. J Neurosci. 2008 Jan 30; 28(5):1198-207.
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    37. Gandy S, Zhang YW, Ikin A, Schmidt SD, Bogush A, Levy E, Sheffield R, Nixon RA, Liao FF, Mathews PM, Xu H, Ehrlich ME. Alzheimer's presenilin 1 modulates sorting of APP and its carboxyl-terminal fragments in cerebral neurons in vivo. J Neurochem. 2007 Aug; 102(3):619-26.
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    38. Bogush A, Pedrini S, Pelta-Heller J, Chan T, Yang Q, Mao Z, Sluzas E, Gieringer T, Ehrlich ME. AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro. J Biol Chem. 2007 Mar 9; 282(10):7352-9.
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    39. Ehrlich M, Woods CB, Yu MC, Dubeau L, Yang F, Campan M, Weisenberger DJ, Long T, Youn B, Fiala ES, Laird PW. Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors. Oncogene. 2006 Apr 27; 25(18):2636-45.
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    40. Ehrlich M. Cancer-linked DNA hypomethylation and its relationship to hypermethylation. Curr Top Microbiol Immunol. 2006; 310:251-74.
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    41. Carter TL, Pedrini S, Ghiso J, Ehrlich ME, Gandy S. Brain neprilysin activity and susceptibility to transgene-induced Alzheimer amyloidosis. Neurosci Lett. 2006 Jan 16; 392(3):235-9.
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    42. Niculescu M, Ehrlich ME, Unterwald EM. Age-specific behavioral responses to psychostimulants in mice. Pharmacol Biochem Behav. 2005 Oct; 82(2):280-8.
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    43. Bogush AI, McCarthy LE, Tian C, Olm V, Gieringer T, Ivkovic S, Ehrlich ME. DARPP-32 genomic fragments drive Cre expression in postnatal striatum. Genesis. 2005 May; 42(1):37-46.
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    44. Nasir I, Kedees MH, Ehrlich ME, Teitelman G. The role of pregnancy hormones in the regulation of Pdx-1 expression. Mol Cell Endocrinol. 2005 Apr 15; 233(1-2):1-13.
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    45. Pedrini S, Carter TL, Prendergast G, Petanceska S, Ehrlich ME, Gandy S. Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. PLoS Med. 2005 Jan; 2(1):e18.
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    46. McCarthy LE, Mannelli P, Niculescu M, Gingrich K, Unterwald EM, Ehrlich ME. The distribution of cocaine in mice differs by age and strain. Neurotoxicol Teratol. 2004 Nov-Dec; 26(6):839-48.
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    47. Carter TL, Verdile G, Groth D, Bogush A, Thomas S, Shen P, Fraser PE, Mathews P, Nixon RA, Ehrlich ME, Kwok JB, St George-Hyslop P, Schofield P, Li Y, Yang A, Martins RN, Gandy S. Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells. Alzheimer Dis Assoc Disord. 2004 Oct-Dec; 18(4):261-3.
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    48. Parvathy S, Ehrlich M, Pedrini S, Diaz N, Refolo L, Buxbaum JD, Bogush A, Petanceska S, Gandy S. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding. J Neurochem. 2004 Aug; 90(4):1005-10.
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    49. Yao J, Petanceska SS, Montine TJ, Holtzman DM, Schmidt SD, Parker CA, Callahan MJ, Lipinski WJ, Bisgaier CL, Turner BA, Nixon RA, Martins RN, Ouimet C, Smith JD, Davies P, Laska E, Ehrlich ME, Walker LC, Mathews PM, Gandy S. Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits. J Neurochem. 2004 Aug; 90(4):1011-8.
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    50. Stroppolo A, Tian C, Guinea B, Olm V, Sheffield R, Sommer J, Ehrlich ME. 17beta-Estradiol promotes striatal medium size spiny neuronal maturation in vitro. Neuroendocrinology. 2004; 79(5):259-67.
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    51. Unterwald EM, Ivkovic S, Cuntapay M, Stroppolo A, Guinea B, Ehrlich ME. Prenatal exposure to cocaine decreases adenylyl cyclase activity in embryonic mouse striatum. Brain Res Dev Brain Res. 2003 Dec 30; 147(1-2):67-75.
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    52. Guitart J, Camisa C, Ehrlich M, Bergfeld WF. Long-term implications of T-cell receptor gene rearrangement analysis by Southern blot in patients with cutaneous T-cell lymphoma. J Am Acad Dermatol. 2003 May; 48(5):775-9.
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    53. Ehrlich ME, Sommer J, Canas E, Unterwald EM. Periadolescent mice show enhanced DeltaFosB upregulation in response to cocaine and amphetamine. J Neurosci. 2002 Nov 1; 22(21):9155-9.
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    54. Glatz AC, Ehrlich M, Bae RS, Clarke MJ, Quinlan PA, Brown EC, Rada P, Hoebel BG. Inhibition of cocaine self-administration by fluoxetine or D-fenfluramine combined with phentermine. Pharmacol Biochem Behav. 2002 Jan-Feb; 71(1-2):197-204.
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    55. Ehrlich M, Buchanan KL, Tsien F, Jiang G, Sun B, Uicker W, Weemaes CM, Smeets D, Sperling K, Belohradsky BH, Tommerup N, Misek DE, Rouillard JM, Kuick R, Hanash SM. DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes. Hum Mol Genet. 2001 Dec 1; 10(25):2917-31.
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    56. Stroppolo A, Guinea B, Tian C, Sommer J, Ehrlich ME. Role of phosphatidylinositide 3-kinase in brain-derived neurotrophic factor-induced DARPP-32 expression in medium size spiny neurons in vitro. J Neurochem. 2001 Dec; 79(5):1027-32.
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    57. Tsien F, Sun B, Hopkins NE, Vedanarayanan V, Figlewicz D, Winokur S, Ehrlich M. Methylation of the FSHD syndrome-linked subtelomeric repeat in normal and FSHD cell cultures and tissues. Mol Genet Metab. 2001 Nov; 74(3):322-31.
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    58. Sun B, Jiang G, Zaydan MA, La Russa VF, Safah H, Ehrlich M. ABL1 promoter methylation can exist independently of BCR-ABL transcription in chronic myeloid leukemia hematopoietic progenitors. Cancer Res. 2001 Sep 15; 61(18):6931-7.
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    59. Schlechta B, Kocher AA, Ehrlich M, Ankersmit J, Ploner M, Walch K, Nourani F, Czerny M, Wolner E, Wollenek G, Grimm M. Outcome of pediatric heart transplantation: an analysis of 27 cases. Transplant Proc. 2001 Aug; 33(5):2834-5.
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    60. Ehrlich M, Shmuely A, Henis YI. A single internalization signal from the di-leucine family is critical for constitutive endocytosis of the type II TGF-beta receptor. J Cell Sci. 2001 May; 114(Pt 9):1777-86.
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    61. Ehrlich ME, Conti L, Toselli M, Taglietti L, Fiorillo E, Taglietti V, Ivkovic S, Guinea B, Tranberg A, Sipione S, Rigamonti D, Cattaneo E. ST14A cells have properties of a medium-size spiny neuron. Exp Neurol. 2001 Feb; 167(2):215-26.
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    62. Narayan A, Tuck-Muller C, Weissbecker K, Smeets D, Ehrlich M. Hypersensitivity to radiation-induced non-apoptotic and apoptotic death in cell lines from patients with the ICF chromosome instability syndrome. Mutat Res. 2000 Nov 30; 456(1-2):1-15.
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    63. Liu X, Sun Y, Ehrlich M, Lu T, Kloog Y, Weinberg RA, Lodish HF, Henis YI. Disruption of TGF-beta growth inhibition by oncogenic ras is linked to p27Kip1 mislocalization. Oncogene. 2000 Nov 30; 19(51):5926-35.
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    64. Kondo T, Bobek MP, Kuick R, Lamb B, Zhu X, Narayan A, Bourc'his D, Viegas-Péquignot E, Ehrlich M, Hanash SM. Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2. Hum Mol Genet. 2000 Mar 1; 9(4):597-604.
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    65. Shenkman M, Ehrlich M, Lederkremer GZ. Masking of an endoplasmic reticulum retention signal by its presence in the two subunits of the asialoglycoprotein receptor. J Biol Chem. 2000 Jan 28; 275(4):2845-51.
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    66. Sengupta PK, Ehrlich M, Smith BD. A methylation-responsive MDBP/RFX site is in the first exon of the collagen alpha2(I) promoter. J Biol Chem. 1999 Dec 17; 274(51):36649-55.
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    67. Kocher AA, Khazen C, Ankersmit J, Ofner P, Schlechta B, Ehrlich M, Wolner E, Laufer G. Midterm results after combined heart and kidney transplantation. Transplant Proc. 1999 Dec; 31(8):3181-3.
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    68. Kocher AA, Ankersmit J, Khazen C, Ofner P, Zuckermann A, Grimm M, Schlechta B, Ehrlich M, Wolner E, Laufer G, Ehrlich E. Effect of obesity on outcome after cardiac transplantation. Transplant Proc. 1999 Dec; 31(8):3187-9.
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    69. Ivkovic S, Ehrlich ME. Expression of the striatal DARPP-32/ARPP-21 phenotype in GABAergic neurons requires neurotrophins in vivo and in vitro. J Neurosci. 1999 Jul 1; 19(13):5409-19.
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    70. Qu GZ, Ehrlich M. Demethylation and expression of methylated plasmid DNA stably transfected into HeLa cells. Nucleic Acids Res. 1999 Jun 1; 27(11):2332-8.
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    71. Magrassi L, Ehrlich ME, Butti G, Pezzotta S, Govoni S, Cattaneo E. Basal ganglia precursors found in aggregates following embryonic transplantation adopt a striatal phenotype in heterotopic locations. Development. 1998 Aug; 125(15):2847-55.
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    72. Dunn SE, Ehrlich M, Sharp NJ, Reiss K, Solomon G, Hawkins R, Baserga R, Barrett JC. A dominant negative mutant of the insulin-like growth factor-I receptor inhibits the adhesion, invasion, and metastasis of breast cancer. Cancer Res. 1998 Aug 1; 58(15):3353-61.
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    73. Ehrlich M, Grabenwoeger M, Cartes-Zumelzu F, Grimm M, Petzl D, Lammer J, Thurnher S, Wolner E, Havel M. Endovascular stent graft repair for aneurysms on the descending thoracic aorta. Ann Thorac Surg. 1998 Jul; 66(1):19-24; discussion 24-5.
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    74. Ortega S, Ittmann M, Tsang SH, Ehrlich M, Basilico C. Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2. Proc Natl Acad Sci U S A. 1998 May 12; 95(10):5672-7.
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    75. Teitelman G, Guz Y, Ivkovic S, Ehrlich M. Islet injury induces neurotrophin expression in pancreatic cells and reactive gliosis of peri-islet Schwann cells. J Neurobiol. 1998 Mar; 34(4):304-18.
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    76. Ivkovic S, Kanazir S, Rakic L, Ehrlich ME, Ruzdijic S. Enhanced serum response element binding activity correlates with down-regulation of c-fos mRNA expression in the rat brain following repeated cortical lesions. Brain Res Mol Brain Res. 1997 Dec 1; 52(1):62-70.
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    77. Grabenwöger M, Ehrlich M, Cartes-Zumelzu F, Mittlböck M, Weigel G, Laufer G, Wolner E, Havel M. Surgical treatment of aortic arch aneurysms in profound hypothermia and circulatory arrest. Ann Thorac Surg. 1997 Oct; 64(4):1067-71.
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    78. Ivkovic S, Polonskaia O, Fariñas I, Ehrlich ME. Brain-derived neurotrophic factor regulates maturation of the DARPP-32 phenotype in striatal medium spiny neurons: studies in vivo and in vitro. Neuroscience. 1997 Jul; 79(2):509-16.
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    79. Ehrlich M, Grabenwöger M, Luckner D, Cartes-Zumelzu F, Simon P, Laufer G, Wolner E, Havel M. The use of profound hypothermia and circulatory arrest in operations on the thoracic aorta. Eur J Cardiothorac Surg. 1997 Jan; 11(1):176-81.
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    80. Ivkovic S, Blau S, Polanskaya O, Ehrlich ME. ARPP-21: murine gene structure and promoter identification of a neuronal phosphoprotein enriched in the limbic striatum. Brain Res. 1996 Feb 12; 709(1):10-6.
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    81. Blau S, Daly L, Fienberg A, Teitelman G, Ehrlich ME. DARPP-32 promoter directs transgene expression to renal thick ascending limb of loop of Henle. Am J Physiol. 1995 Oct; 269(4 Pt 2):F564-70.
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    82. Saifudeen Z, Desnick RJ, Ehrlich M. A mutation in the 5' untranslated region of the human alpha-galactosidase A gene in high-activity variants inhibits specific protein binding. FEBS Lett. 1995 Sep 4; 371(2):181-4.
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    83. Zhang XY, Ni YS, Saifudeen Z, Asiedu CK, Supakar PC, Ehrlich M. Increasing binding of a transcription factor immediately downstream of the cap site of a cytomegalovirus gene represses expression. Nucleic Acids Res. 1995 Aug 11; 23(15):3026-33.
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    84. Warshamana GS, Qu GZ, Zhang XY, Ji W, Ehrlich M. Reporter gene expression upon stable transfection when only a TATA box or a TATA box plus Sp1 sites are present 5' to the gene. DNA Cell Biol. 1995 Aug; 14(8):709-17.
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    85. Ji W, Qu GZ, Ye P, Zhang XY, Halabi S, Ehrlich M. Frequent detection of bcl-2/JH translocations in human blood and organ samples by a quantitative polymerase chain reaction assay. Cancer Res. 1995 Jul 1; 55(13):2876-82.
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    86. Desdouits F, Cheetham JJ, Huang HB, Kwon YG, da Cruz e Silva EF, Denefle P, Ehrlich ME, Nairn AC, Greengard P, Girault JA. Mechanism of inhibition of protein phosphatase 1 by DARPP-32: studies with recombinant DARPP-32 and synthetic peptides. Biochem Biophys Res Commun. 1995 Jan 17; 206(2):652-8.
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    87. Wainwright MS, Perry BD, Won LA, O'Malley KL, Wang WY, Ehrlich ME, Heller A. Immortalized murine striatal neuronal cell lines expressing dopamine receptors and cholinergic properties. J Neurosci. 1995 Jan; 15(1 Pt 2):676-88.
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    88. Ji W, Zhang XY, Warshamana GS, Qu GZ, Ehrlich M. Effect of internal direct and inverted Alu repeat sequences on PCR. PCR Methods Appl. 1994 Oct; 4(2):109-16.
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    89. Asiedu CK, Scotto L, Assoian RK, Ehrlich M. Binding of AP-1/CREB proteins and of MDBP to contiguous sites downstream of the human TGF-beta 1 gene. Biochim Biophys Acta. 1994 Sep 13; 1219(1):55-63.
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    90. Ehrlich ME, Evinger M, Regunathan S, Teitelman G. Mammalian adrenal chromaffin cells coexpress the epinephrine-synthesizing enzyme and neuronal properties in vivo and in vitro. Dev Biol. 1994 Jun; 163(2):480-90.
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    91. Zhang XY, Ehrlich M. Detection and quantitation of low numbers of chromosomes containing bcl-2 oncogene translocations using semi-nested PCR. Biotechniques. 1994 Mar; 16(3):502-7.
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    92. Brené S, Lindefors N, Ehrlich M, Taubes T, Horiuchi A, Kopp J, Hall H, Sedvall G, Greengard P, Persson H. Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue. J Neurosci. 1994 Mar; 14(3 Pt 1):985-98.
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    93. Zhang XY, Jabrane-Ferrat N, Asiedu CK, Samac S, Peterlin BM, Ehrlich M. The major histocompatibility complex class II promoter-binding protein RFX (NF-X) is a methylated DNA-binding protein. Mol Cell Biol. 1993 Nov; 13(11):6810-8.
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    94. Canoll PD, Barnea G, Levy JB, Sap J, Ehrlich M, Silvennoinen O, Schlessinger J, Musacchio JM. The expression of a novel receptor-type tyrosine phosphatase suggests a role in morphogenesis and plasticity of the nervous system. Brain Res Dev Brain Res. 1993 Oct 15; 75(2):293-8.
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    95. Gustafson EL, Ehrlich ME, Trivedi P, Greengard P. Developmental regulation of phosphoprotein gene expression in the caudate-putamen of rat: an in situ hybridization study. Neuroscience. 1992 Nov; 51(1):65-75.
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    96. Ehrlich KC, Cary JW, Ehrlich M. A broad bean cDNA clone encoding a DNA-binding protein resembling mammalian CREB in its sequence specificity and DNA methylation sensitivity. Gene. 1992 Aug 15; 117(2):169-78.
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    97. Sedvall CG, Farde L, Hall H, Halldin C, Karlsson P, Brene S, Lindefors N, Persson H, Chipkin RE, Ehrlich M, et al. Ligand selection for PET studies of D1 dopamine receptors. Relationship between distribution of binding sites and mRNA for DAARPP32 in the human brain. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:466A-467A.
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    98. Ehrlich ME, Greengard P. Characterization of rat ARPP-21 mRNA: sequence analysis, tissue distribution, and regulation. J Neurochem. 1991 Dec; 57(6):1985-91.
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    99. Asiedu CK, Supakar PC, Ehrlich M. End-filling of an oligonucleotide duplex containing an MDBP site in the human HSP70 promoter inhibits protein-DNA complex formation. Biochem Biophys Res Commun. 1991 Aug 15; 178(3):927-33.
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    100. Inamdar NM, Ehrlich KC, Ehrlich M. CpG methylation inhibits binding of several sequence-specific DNA-binding proteins from pea, wheat, soybean and cauliflower. Plant Mol Biol. 1991 Jul; 17(1):111-23.
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    101. Zhang XY, Inamdar NM, Supakar PC, Wu K, Ehrlich KC, Ehrlich M. Three MDBP sites in the immediate-early enhancer-promoter region of human cytomegalovirus. Virology. 1991 Jun; 182(2):865-9.
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    102. Zhang XY, Asiedu CK, Supakar PC, Khan R, Ehrlich KC, Ehrlich M. Binding sites in mammalian genes and viral gene regulatory regions recognized by methylated DNA-binding protein. Nucleic Acids Res. 1990 Nov 11; 18(21):6253-60.
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    103. Zhang XY, Supakar PC, Wu KZ, Ehrlich KC, Ehrlich M. An MDBP site in the first intron of the human c-myc gene. Cancer Res. 1990 Nov 1; 50(21):6865-9.
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    104. Ehrlich KC, Ehrlich M. Highly repeated sites in the apolipoprotein(a) gene recognized by methylated DNA-binding protein, a sequence-specific DNA-binding protein. Mol Cell Biol. 1990 Sep; 10(9):4957-60.
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    105. Buxbaum JD, Gandy SE, Cicchetti P, Ehrlich ME, Czernik AJ, Fracasso RP, Ramabhadran TV, Unterbeck AJ, Greengard P. Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation. Proc Natl Acad Sci U S A. 1990 Aug; 87(15):6003-6.
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    106. Grebb JA, Girault JA, Ehrlich M, Greengard P. Chronic treatment of rats with SCH-23390 or raclopride does not affect the concentrations of DARPP-32 or its mRNA in dopamine-innervated brain regions. J Neurochem. 1990 Jul; 55(1):204-7.
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    107. Ehrlich ME, Rosen NL, Kurihara T, Shalaby IA, Greengard P. DARPP-32 development in the caudate nucleus is independent of afferent input from the substantia nigra. Brain Res Dev Brain Res. 1990 Jul 1; 54(2):257-63.
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    108. Schalling M, Dagerlind A, Goldstein M, Ehrlich M, Greengard P, Hökfelt T. Comparison of gene expression of the dopamine D-2 receptor and DARPP-32 in rat brain, pituitary and adrenal gland. Eur J Pharmacol. 1990 Apr 25; 188(4-5):277-81.
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    109. Ehrlich ME, Grillo M, Joh TH, Margolis FL, Baker H. Transneuronal regulation of neuronal specific gene expression in the mouse olfactory bulb. Brain Res Mol Brain Res. 1990 Feb; 7(2):115-22.
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    110. Schalling M, Djurfeldt M, Hökfelt T, Ehrlich M, Kurihara T, Greengard P. Distribution and cellular localization of DARPP-32 mRNA in rat brain. Brain Res Mol Brain Res. 1990 Feb; 7(2):139-49.
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    111. Ehrlich ME, Kurihara T, Greengard P. Rat DARPP-32: cloning, sequencing, and characterization of the cDNA. J Mol Neurosci. 1990; 2(1):1-10.
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    112. Meister B, Villar MJ, Schalling M, Ehrlich M, Greengard P, Hökfelt T. Demonstration of DARPP-32 in pituicytes of the neurohypophysis-decreased expression after administration of hyperosmotic stimuli. Acta Physiol Scand. 1989 Nov; 137(3):461-2.
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    113. Ehrlich ME, Evinger MJ, Joh TH, Teitelman G. Do glucocorticoids induce adrenergic differentiation in adrenal cells of neural crest origin? Brain Res Dev Brain Res. 1989 Nov 1; 50(1):129-37.
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    114. Meister B, Fryckstedt J, Schalling M, Cortés R, Hökfelt T, Aperia A, Hemmings HC, Nairn AC, Ehrlich M, Greengard P. Dopamine- and cAMP-regulated phosphoprotein (DARPP-32) and dopamine DA1 agonist-sensitive Na+,K+-ATPase in renal tubule cells. Proc Natl Acad Sci U S A. 1989 Oct; 86(20):8068-72.
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    115. Kurihara T, Ehrlich ME, Horiuchi J, Nasu T, Greengard P. ARPP-21, a cyclic AMP-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Molecular cloning and nucleotide sequence. J Neurosci. 1989 Oct; 9(10):3638-44.
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    116. Zhang XY, Supakar PC, Khan R, Ehrlich KC, Ehrlich M. Related sites in human and herpesvirus DNA recognized by methylated DNA-binding protein from human placenta. Nucleic Acids Res. 1989 Feb 25; 17(4):1459-74.
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    117. Khan R, Zhang XY, Supakar PC, Ehrlich KC, Ehrlich M. Human methylated DNA-binding protein. Determinants of a pBR322 recognition site. J Biol Chem. 1988 Oct 5; 263(28):14374-83.
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    118. Supakar PC, Weist D, Zhang DL, Inamdar N, Zhang XY, Khan R, Ehrlich KC, Ehrlich M. Methylated DNA-binding protein is present in various mammalian cell types. Nucleic Acids Res. 1988 Aug 25; 16(16):8029-44.
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    119. Ehrlich ME, Lavyne MH. Aneurysmal subarachnoid hemorrhage in a child with leukemia. Surg Neurol. 1988 Aug; 30(2):144-7.
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    120. Zhang XY, Loflin PT, Gehrke CW, Andrews PA, Ehrlich M. Hypermethylation of human DNA sequences in embryonal carcinoma cells and somatic tissues but not in sperm. Nucleic Acids Res. 1987 Nov 25; 15(22):9429-49.
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    121. Wang RY, Zhang XY, Khan R, Zhou YW, Huang LH, Ehrlich M. Methylated DNA-binding protein from human placenta recognizes specific methylated sites on several prokaryotic DNAs. Nucleic Acids Res. 1986 Dec 22; 14(24):9843-60.
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    122. Zhang XY, Ehrlich KC, Wang RY, Ehrlich M. Effect of site-specific DNA methylation and mutagenesis on recognition by methylated DNA-binding protein from human placenta. Nucleic Acids Res. 1986 Nov 11; 14(21):8387-97.
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    123. Ehrlich M, Norris KF, Wang RY, Kuo KC, Gehrke CW. DNA cytosine methylation and heat-induced deamination. Biosci Rep. 1986 Apr; 6(4):387-93.
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    124. Wang RY, Zhang XY, Ehrlich M. A human DNA-binding protein is methylation-specific and sequence-specific. Nucleic Acids Res. 1986 Feb 25; 14(4):1599-614.
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    125. Zhang XY, Wang RY, Ehrlich M. Human DNA sequences exhibiting gamete-specific hypomethylation. Nucleic Acids Res. 1985 Jul 11; 13(13):4837-51.
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    126. Ehrlich M, Zhang XY, Wang RY. Human DNA methylation: methylated DNA-binding protein, differentiation and cancer. Prog Clin Biol Res. 1985; 198:255-69.
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    127. Breznik T, Traina-Dorge V, Gama-Sosa M, Gehrke CW, Ehrlich M, Medina D, Butel JS, Cohen JC. Mouse mammary tumor virus DNA methylation: tissue-specific variation. Virology. 1984 Jul 15; 136(1):69-77.
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    128. Wang RY, Huang LH, Ehrlich M. Human placental DNA methyltransferase: DNA substrate and DNA binding specificity. Nucleic Acids Res. 1984 Apr 25; 12(8):3473-90.
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    129. Huang LH, Wang R, Gama-Sosa MA, Shenoy S, Ehrlich M. A protein from human placental nuclei binds preferentially to 5-methylcytosine-rich DNA. Nature. 1984 Mar 15-21; 308(5956):293-5.
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    130. Wang RY, Shenoy S, Ehrlich M. DNA methylation inhibits the transfecting activity of replicative- form phi X174 DNA. J Virol. 1984 Mar; 49(3):674-9.
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    131. Voorhies TM, Ehrlich ME, Duffy TE, Petito CK, Plum F. Acute hyperammonemia in the young primate: physiologic and neuropathologic correlates. Pediatr Res. 1983 Dec; 17(12):970-5.
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    132. Gama-Sosa MA, Wang RY, Kuo KC, Gehrke CW, Ehrlich M. The 5-methylcytosine content of highly repeated sequences in human DNA. Nucleic Acids Res. 1983 May 25; 11(10):3087-95.
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    133. Wang RY, Kuo KC, Gehrke CW, Huang LH, Ehrlich M. Heat- and alkali-induced deamination of 5-methylcytosine and cytosine residues in DNA. Biochim Biophys Acta. 1982 Jun 30; 697(3):371-7.
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    134. Wang RY, Huang LH, Ehrlich M. Enzymatic conversion of deoxycytidine 5'-monophosphate to 5-methyldeoxycytidine 5'-triphosphate. Anal Biochem. 1982 May 1; 122(1):89-93.
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    135. Ehrlich M, Gama-Sosa MA, Huang LH, Midgett RM, Kuo KC, McCune RA, Gehrke C. Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells. Nucleic Acids Res. 1982 Apr 24; 10(8):2709-21.
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    136. Wang RY, Ehrlich M. 5-methyl-dCTP deaminase induced by bacteriophage XP-12. J Virol. 1982 Apr; 42(1):42-8.
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    137. Wang RY, Huang LH, Ehrlich M. A bacteriophage-induced 5-methyldeoxycytidine 5'-monophosphate kinase. Biochim Biophys Acta. 1982 Jan 26; 696(1):31-6.
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    138. Ehrlich M, Ehrlich KC. A novel, highly modified, bacteriophage DNA in which thymine is partly replaced by a phosphoglucuronate moiety covalently bound to 5-(4',5'-dihydroxypentyl)uracil. J Biol Chem. 1981 Oct 10; 256(19):9966-72.
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    139. Ehrlich M, Wang RY. 5-Methylcytosine in eukaryotic DNA. Science. 1981 Jun 19; 212(4501):1350-7.
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    140. Wang RY, Gehrke CW, Ehrlich M. Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues. Nucleic Acids Res. 1980 Oct 24; 8(20):4777-90.
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    141. Ehrlich M, Plum F, Duffy TE. Blood and brain ammonia concentrations after portacaval anastomosis. Effects of acute ammonia loading. J Neurochem. 1980 Jun; 34(6):1538-42.
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    142. Wang RY, Shedlarski JG, Farber MB, Kuebbing D, Ehrlich M. Two sequence-specific endonucleases from Xanthomonas oryzae. Characterization and unusual properties. Biochim Biophys Acta. 1980 Feb 29; 606(2):371-85.
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    143. Ehrlich M, Sarafyan LP, Myers DJ. Interaction of microbial DNA with cultured mammalian cells. Binding of the donor DNA to the cell surface. Biochim Biophys Acta. 1976 Dec 13; 454(3):397-409.
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