Keywords
Last Name
Institution

Stephen Ward

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentPathology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Weinstock B, Ward SC, Harpaz N, Warner RR, Itzkowitz S, Kim MK. Clinical and prognostic features of rectal neuroendocrine tumors. Neuroendocrinology. 2013; 98(3):180-7.
      View in: PubMed
    2. Kim MK, Warner RR, Roayaie S, Harpaz N, Ward SC, Itzkowitz S, Wisnivesky JP. Revised staging classification improves outcome prediction for small intestinal neuroendocrine tumors. J Clin Oncol. 2013 Oct 20; 31(30):3776-81.
      View in: PubMed
    3. Cravedi P, Leventhal J, Lakhani P, Ward SC, Donovan MJ, Heeger PS. Immune cell-derived C3a and C5a costimulate human T cell alloimmunity. Am J Transplant. 2013 Oct; 13(10):2530-9.
      View in: PubMed
    4. Lewis S, Roayaie S, Ward SC, Shyknevsky I, Jibara G, Taouli B. Hepatocellular carcinoma in chronic hepatitis C in the absence of advanced fibrosis or cirrhosis. AJR Am J Roentgenol. 2013 Jun; 200(6):W610-6.
      View in: PubMed
    5. Lu Y, Ward SC, Cederbaum AI. Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver. Alcohol. 2013 Aug; 47(5):353-7.
      View in: PubMed
    6. Im GY, Sehgal V, Ward SC. A case of undulating fevers and elevated liver tests after pancreas-kidney transplantation. Semin Liver Dis. 2013 Feb; 33(1):89-93.
      View in: PubMed
    7. Harpaz N, Ward SC, Mescoli C, Itzkowitz SH, Polydorides AD. Precancerous lesions in inflammatory bowel disease. Best Pract Res Clin Gastroenterol. 2013 Apr; 27(2):257-67.
      View in: PubMed
    8. Eisenstein S, Coakley BA, Briley-Saebo K, Ma G, Chen HM, Meseck M, Ward S, Divino C, Woo S, Chen SH, Pan PY. Myeloid-derived suppressor cells as a vehicle for tumor-specific oncolytic viral therapy. Cancer Res. 2013 Aug 15; 73(16):5003-15.
      View in: PubMed
    9. Foster JG, Carter E, Kilty I, MacKenzie AB, Ward SG. Mitochondrial superoxide generation enhances P2X7R-mediated loss of cell surface CD62L on naive human CD4+ T lymphocytes. J Immunol. 2013 Feb 15; 190(4):1551-9.
      View in: PubMed
    10. Harris SJ, Ciuclan L, Finan PM, Wymann MP, Walker C, Westwick J, Ward SG, Thomas MJ. Genetic ablation of PI3K? results in defective IL-17RA signalling in T lymphocytes and increased IL-17 levels. Eur J Immunol. 2012 Dec; 42(12):3394-404.
      View in: PubMed
    11. Shrager B, Jibara GA, Tabrizian P, Roayaie S, Ward SC. Resection of nonalcoholic steatohepatitis-associated hepatocellular carcinoma: a Western experience. Int J Surg Oncol. 2012; 2012:915128.
      View in: PubMed
    12. Bhasin D, Zhang X, Ward SC, Chang CY. A case of quadruple viral infections and elevated aminotransferase activities. Semin Liver Dis. 2012 Aug; 32(3):262-6.
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    13. Ko HM, Hernandez-Prera JC, Zhu H, Dikman SH, Sidhu HK, Ward SC, Thung SN. Morphologic features of extrahepatic manifestations of hepatitis C virus infection. Clin Dev Immunol. 2012; 2012:740138.
      View in: PubMed
    14. Lachenmayer A, Alsinet C, Savic R, Cabellos L, Toffanin S, Hoshida Y, Villanueva A, Minguez B, Newell P, Tsai HW, Barretina J, Thung S, Ward SC, Bruix J, Mazzaferro V, Schwartz M, Friedman SL, Llovet JM. Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib. Clin Cancer Res. 2012 Sep 15; 18(18):4997-5007.
      View in: PubMed
    15. Leung TM, Lu Y, Yan W, Morón-Concepción JA, Ward SC, Ge X, Conde de la Rosa L, Nieto N. Argininosuccinate synthase conditions the response to acute and chronic ethanol-induced liver injury in mice. Hepatology. 2012 May; 55(5):1596-609.
      View in: PubMed
    16. Lewis JR, Itzkowitz S, Zhu H, Ward SC, Anandasabapathy S. Sequential downgrading of dysplasia in ulcerative colitis using carbon dioxide-based cryotherapy. Endoscopy. 2012; 44 Suppl 2 UCTN:E96-7.
      View in: PubMed
    17. Ward SC, Rosen A. Magnetic resonance imaging characterization of hepatocellular carcinoma expressing progenitor cell markers. Liver Int. 2012 Mar; 32(3):349-51.
      View in: PubMed
    18. Requena-Méndez A, Davies G, Ardrey A, Jave O, López-Romero SL, Ward SA, Moore DA. Pharmacokinetics of rifampin in Peruvian tuberculosis patients with and without comorbid diabetes or HIV. Antimicrob Agents Chemother. 2012 May; 56(5):2357-63.
      View in: PubMed
    19. Lachenmayer A, Toffanin S, Cabellos L, Alsinet C, Hoshida Y, Villanueva A, Minguez B, Tsai HW, Ward SC, Thung S, Friedman SL, Llovet JM. Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib. J Hepatol. 2012 Jun; 56(6):1343-50.
      View in: PubMed
    20. Lu Y, Leung TM, Ward SC, Nieto N. Partial deletion of argininosuccinate synthase protects from pyrazole plus lipopolysaccharide-induced liver injury by decreasing nitrosative stress. Am J Physiol Gastrointest Liver Physiol. 2012 Feb 1; 302(3):G287-95.
      View in: PubMed
    21. Curran T, Tulin-Silver S, Patel K, Ward S, Schneiderman M, Harpaz N, Schwartz M, Itzkowitz S, Warner RR, Kim MK. Prognostic clinicopathologic factors in longitudinally followed patients with metastatic small bowel carcinoid tumors. Pancreas. 2011 Nov; 40(8):1253-7.
      View in: PubMed
    22. Sempoux C, Jibara G, Ward SC, Fan C, Qin L, Roayaie S, Fiel MI, Schwartz M, Thung SN. Intrahepatic cholangiocarcinoma: new insights in pathology. Semin Liver Dis. 2011 Feb; 31(1):49-60.
      View in: PubMed
    23. Ward SC, Waxman S. Fibrolamellar carcinoma: a review with focus on genetics and comparison to other malignant primary liver tumors. Semin Liver Dis. 2011 Feb; 31(1):61-70.
      View in: PubMed
    24. Toffanin S, Hoshida Y, Lachenmayer A, Villanueva A, Cabellos L, Minguez B, Savic R, Ward SC, Thung S, Chiang DY, Alsinet C, Tovar V, Roayaie S, Schwartz M, Bruix J, Waxman S, Friedman SL, Golub T, Mazzaferro V, Llovet JM. MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a. Gastroenterology. 2011 May; 140(5):1618-28.e16.
      View in: PubMed
    25. Zhu H, Sun K, Ward SC, Schwartz M, Thung SN, Qin L. Primary hepatic signet ring cell neuroendocrine tumor: a case report with literature review. Semin Liver Dis. 2010 Nov; 30(4):422-8.
      View in: PubMed
    26. Lu Y, Wu D, Wang X, Ward SC, Cederbaum AI. Chronic alcohol-induced liver injury and oxidant stress are decreased in cytochrome P4502E1 knockout mice and restored in humanized cytochrome P4502E1 knock-in mice. Free Radic Biol Med. 2010 Nov 15; 49(9):1406-16.
      View in: PubMed
    27. Ward SC, Huang J, Tickoo SK, Thung SN, Ladanyi M, Klimstra DS. Fibrolamellar carcinoma of the liver exhibits immunohistochemical evidence of both hepatocyte and bile duct differentiation. Mod Pathol. 2010 Sep; 23(9):1180-90.
      View in: PubMed
    28. Dhillon N, Walsh L, Krüger B, Ward SC, Godbold JH, Radwan M, Schiano T, Murphy BT, Schröppel B. A single nucleotide polymorphism of Toll-like receptor 4 identifies the risk of developing graft failure after liver transplantation. J Hepatol. 2010 Jul; 53(1):67-72.
      View in: PubMed
    29. Dhillon N, Walsh L, Krüger B, Mehrotra A, Ward SC, Godbold J, Radwan M, Schiano T, Murphy B, Schröppel B. Complement component C3 allotypes and outcomes in liver transplantation. Liver Transpl. 2010 Feb; 16(2):198-203.
      View in: PubMed
    30. Ward SC, Schiano TD, Thung SN, Fiel MI. Plasma cell hepatitis in hepatitis C virus patients post-liver transplantation: case-control study showing poor outcome and predictive features in the liver explant. Liver Transpl. 2009 Dec; 15(12):1826-33.
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    31. Tiono AB, Dicko A, Ndububa DA, Agbenyega T, Pitmang S, Awobusuyi J, Pamba A, Duparc S, Goh LE, Harrell E, Carter N, Ward SA, Greenwood B, Winstanley PA. Chlorproguanil-dapsone-artesunate versus chlorproguanil-dapsone: a randomized, double-blind, phase III trial in African children, adolescents, and adults with uncomplicated Plasmodium falciparum malaria. Am J Trop Med Hyg. 2009 Dec; 81(6):969-78.
      View in: PubMed
    32. Ward SC, Thung SN, Lim KH, Tran TT, Hong TK, Hoang PL, Jang JJ, Park YN, Abe K. Hepatic progenitor cells in liver cancers from Asian children. Liver Int. 2010 Jan; 30(1):102-11.
      View in: PubMed
    33. Weatherburn G, Ward S, Johnston G, Chisholm S. Off-site expert support for nurses undertaking ECGs in primary care. Br J Nurs. 2009 May 14-27; 18(9):551-4.
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    34. Ward SC, Chang CY, Peng L, Liu LU. Patient with hepatitis B and alcoholic liver disease before and after liver transplantation. Semin Liver Dis. 2009 May; 29(2):233-7.
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    35. O'Neill PM, Shone AE, Stanford D, Nixon G, Asadollahy E, Park BK, Maggs JL, Roberts P, Stocks PA, Biagini G, Bray PG, Davies J, Berry N, Hall C, Rimmer K, Winstanley PA, Hindley S, Bambal RB, Davis CB, Bates M, Gresham SL, Brigandi RA, Gomez-de-Las-Heras FM, Gargallo DV, Parapini S, Vivas L, Lander H, Taramelli D, Ward SA. Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable "back-up" compound for N-tert-butyl isoquine. J Med Chem. 2009 Apr 9; 52(7):1828-44.
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    36. Jones M, Mercer AE, Stocks PA, La Pensée LJ, Cosstick R, Park BK, Kennedy ME, Piantanida I, Ward SA, Davies J, Bray PG, Rawe SL, Baird J, Charidza T, Janneh O, O'Neill PM. Antitumour and antimalarial activity of artemisinin-acridine hybrids. Bioorg Med Chem Lett. 2009 Apr 1; 19(7):2033-7.
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    37. Saland JM, Shneider BL, Bromberg JS, Shi PA, Ward SC, Magid MS, Benchimol C, Seikaly MG, Emre SH, Bresin E, Remuzzi G. Successful split liver-kidney transplant for factor H associated hemolytic uremic syndrome. Clin J Am Soc Nephrol. 2009 Jan; 4(1):201-6.
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    38. Lim KH, Ward SC, Roayaie S, Cohen E, Schwartz M, Fiel MI, Thung SN. Multiple inflammatory and serum amyloid A positive telangiectatic hepatic adenomas with glycogenated nuclei arising in a background of nonalcoholic steatohepatitis. Semin Liver Dis. 2008 Nov; 28(4):434-9.
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    39. Ochong E, Bell DJ, Johnson DJ, D'Alessandro U, Mulenga M, Muangnoicharoen S, Van Geertruyden JP, Winstanley PA, Bray PG, Ward SA, Owen A. Plasmodium falciparum strains harboring dihydrofolate reductase with the I164L mutation are absent in Malawi and Zambia even under antifolate drug pressure. Antimicrob Agents Chemother. 2008 Nov; 52(11):3883-8.
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    40. Whitt KN, Ward SC, Deniz K, Liu L, Odin JA, Qin L. Cholestatic liver injury associated with whey protein and creatine supplements. Semin Liver Dis. 2008 May; 28(2):226-31.
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    41. Wright KL, Robertson DA, Moyer MP, Ward SG. Long term cannabinoid receptor (CB1) blockade in obesity: implications for the development of colorectal cancer. Int J Cancer. 2008 Apr 15; 122(8):1920-1.
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    42. Deniz K, Ward SC, Rosen A, Grewal P, Xu R. Budd-Chiari syndrome in sarcoidosis involving liver. Liver Int. 2008 Apr; 28(4):580-1.
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    43. Wootton DG, Opara H, Biagini GA, Kanjala MK, Duparc S, Kirby PL, Woessner M, Neate C, Nyirenda M, Blencowe H, Dube-Mbeye Q, Kanyok T, Ward S, Molyneux M, Dunyo S, Winstanley PA. Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria. PLoS One. 2008; 3(3):e1779.
      View in: PubMed
    44. Ward SC, Deniz K, Roayaie S, Qin L. Multifocal hepatocellular carcinoma and precancerous lesions in a patient with autoimmune hepatitis-related cirrhosis. Semin Liver Dis. 2008 Feb; 28(1):123-7.
      View in: PubMed
    45. Hartkoorn RC, Khoo S, Back DJ, Tjia JF, Waitt CJ, Chaponda M, Davies G, Ardrey A, Ashleigh S, Ward SA. A rapid and sensitive HPLC-MS method for the detection of plasma and cellular rifampicin. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 15; 857(1):76-82.
      View in: PubMed
    46. Hartkoorn RC, Chandler B, Owen A, Ward SA, Bertel Squire S, Back DJ, Khoo SH. Differential drug susceptibility of intracellular and extracellular tuberculosis, and the impact of P-glycoprotein. Tuberculosis (Edinb). 2007 May; 87(3):248-55.
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    47. Graham SM, Bell DJ, Nyirongo S, Hartkoorn R, Ward SA, Molyneux EM. Low levels of pyrazinamide and ethambutol in children with tuberculosis and impact of age, nutritional status, and human immunodeficiency virus infection. Antimicrob Agents Chemother. 2006 Feb; 50(2):407-13.
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    48. Wain CM, Westwick J, Ward SG. Heterologous regulation of chemokine receptor signaling by the lipid phosphatase SHIP in lymphocytes. Cell Signal. 2005 Oct; 17(10):1194-202.
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    49. Fuld JP, Kilduff LP, Neder JA, Pitsiladis Y, Lean ME, Ward SA, Cotton MM. Creatine supplementation during pulmonary rehabilitation in chronic obstructive pulmonary disease. Thorax. 2005 Jul; 60(7):531-7.
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    50. Kolios G, Valatas V, Ward SG. Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle. Immunology. 2004 Dec; 113(4):427-37.
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    51. Winstanley P, Ward S, Snow R, Breckenridge A. Therapy of falciparum malaria in sub-saharan Africa: from molecule to policy. Clin Microbiol Rev. 2004 Jul; 17(3):612-37, table of contents.
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    52. Alloueche A, Bailey W, Barton S, Bwika J, Chimpeni P, Falade CO, Fehintola FA, Horton J, Jaffar S, Kanyok T, Kremsner PG, Kublin JG, Lang T, Missinou MA, Mkandala C, Oduola AM, Premji Z, Robertson L, Sowunmi A, Ward SA, Winstanley PA. Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial. Lancet. 2004 Jun 5; 363(9424):1843-8.
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    53. Heit JA, Phelps MA, Ward SA, Slusser JP, Petterson TM, De Andrade M. Familial segregation of venous thromboembolism. J Thromb Haemost. 2004 May; 2(5):731-6.
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    54. Curnock AP, Sotsios Y, Wright KL, Ward SG. Optimal chemotactic responses of leukemic T cells to stromal cell-derived factor-1 requires the activation of both class IA and IB phosphoinositide 3-kinases. J Immunol. 2003 Apr 15; 170(8):4021-30.
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    55. O'Neill LA, Brown Z, Ward SG. Toll-like receptors in the spotlight. Nat Immunol. 2003 Apr; 4(4):299.
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    56. Freeburn RW, Wright KL, Burgess SJ, Astoul E, Cantrell DA, Ward SG. Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors. J Immunol. 2002 Nov 15; 169(10):5441-50.
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    57. Ward SA, Bray PG. Is reversal of chloroquine resistance ready for the clinic? Lancet. 2001 Mar 24; 357(9260):904.
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    58. Rawden HC, Kokwaro GO, Ward SA, Edwards G. Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes. Br J Clin Pharmacol. 2000 Apr; 49(4):313-22.
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    59. Helsby NA, Ward SA, Parslew RA, Friedmann PS, Rhodes LE. Hepatic cytochrome P450 CYP2C activity in psoriasis: studies using proguanil as a probe compound. Acta Derm Venereol. 1998 Mar; 78(2):81-3.
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    60. McLean WG, Ward SA. In vitro neurotoxicity of artemisinin derivatives. Med Trop (Mars). 1998; 58(3 Suppl):28-31.
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    61. Ndifor AM, Howells RE, Bray PG, Ngu JL, Ward SA. Enhancement of drug susceptibility in Plasmodium falciparum in vitro and Plasmodium berghei in vivo by mixed-function oxidase inhibitors. Antimicrob Agents Chemother. 1993 Jun; 37(6):1318-23.
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    62. Kokwaro GO, Glazier AP, Ward SA, Breckenridge AM, Edwards G. Effect of malaria infection and endotoxin-induced fever on phenacetin O-deethylation by rat liver microsomes. Biochem Pharmacol. 1993 Mar 24; 45(6):1235-41.
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    63. Helsby NA, Watkins WM, Mberu E, Ward SA. Inter-individual variation in the metabolic activation of the antimalarial biguanides. Parasitol Today. 1991 May; 7(5):120-3.
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067