Keywords
Last Name
Institution

Peter S. Heeger

TitlePROFESSOR
InstitutionMount Sinai
DepartmentNephrology
Address

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kalache S, Lakhani P, Heeger PS. Effects of Preexisting Autoimmunity on Heart Graft Prolongation After Donor-Specific Transfusion and Anti-CD154. Transplantation. 2014 Jan 15; 97(1):12-9.
      View in: PubMed
    2. Tinckam KJ, Heeger PS. Transplantation: Complementing donor-specific antibody testing. Nat Rev Nephrol. 2013 Dec; 9(12):713-4.
      View in: PubMed
    3. Cravedi P, van der Touw W, Heeger PS. Complement regulation of T-cell alloimmunity. Semin Nephrol. 2013 Nov; 33(6):565-74.
      View in: PubMed
    4. Reed EF, Rao P, Zhang Z, Gebel H, Bray RA, Guleria I, Lunz J, Mohanakumar T, Nickerson P, Tambur AR, Zeevi A, Heeger PS, Gjertson D. Comprehensive assessment and standardization of solid phase multiplex-bead arrays for the detection of antibodies to HLA-drilling down on key sources of variation. Am J Transplant. 2013 Nov; 13(11):3050-1.
      View in: PubMed
    5. Cravedi P, Leventhal J, Lakhani P, Ward SC, Donovan MJ, Heeger PS. Immune cell-derived C3a and C5a costimulate human T cell alloimmunity. Am J Transplant. 2013 Oct; 13(10):2530-9.
      View in: PubMed
    6. Hricik DE, Nickerson P, Formica RN, Poggio ED, Rush D, Newell KA, Goebel J, Gibson IW, Fairchild RL, Riggs M, Spain K, Ikle D, Bridges ND, Heeger PS. Multicenter validation of urinary CXCL9 as a risk-stratifying biomarker for kidney transplant injury. Am J Transplant. 2013 Oct; 13(10):2634-44.
      View in: PubMed
    7. Cravedi P, Lessman DA, Heeger PS. Eosinophils are not required for the induction and maintenance of an alloantibody response. Am J Transplant. 2013 Oct; 13(10):2696-702.
      View in: PubMed
    8. Suthanthiran M, Schwartz JE, Ding R, Abecassis M, Dadhania D, Samstein B, Knechtle SJ, Friedewald J, Becker YT, Sharma VK, Williams NM, Chang CS, Hoang C, Muthukumar T, August P, Keslar KS, Fairchild RL, Hricik DE, Heeger PS, Han L, Liu J, Riggs M, Ikle DN, Bridges ND, Shaked A. Urinary-cell mRNA profile and acute cellular rejection in kidney allografts. N Engl J Med. 2013 Jul 4; 369(1):20-31.
      View in: PubMed
    9. Keslar KS, Lin M, Zmijewska AA, Sigdel TK, Tran TQ, Ma L, Bhasin M, Rao P, Ding R, Iklé DN, Mannon RB, Sarwal MM, Strom TB, Reed EF, Heeger PS, Suthanthiran M, Fairchild RL. Multicenter evaluation of a standardized protocol for noninvasive gene expression profiling. Am J Transplant. 2013 Jul; 13(7):1891-7.
      View in: PubMed
    10. Reed EF, Rao P, Zhang Z, Gebel H, Bray RA, Guleria I, Lunz J, Mohanakumar T, Nickerson P, Tambur AR, Zeevi A, Heeger PS, Gjertson D. Comprehensive assessment and standardization of solid phase multiplex-bead arrays for the detection of antibodies to HLA. Am J Transplant. 2013 Jul; 13(7):1859-70.
      View in: PubMed
    11. Hricik DE, Poggio ED, Woodside KJ, Sarabu N, Sanchez EQ, Schulak JA, Padiyar A, Heeger PS, Augustine JJ. Effects of cellular sensitization and donor age on acute rejection and graft function after deceased-donor kidney transplantation. Transplantation. 2013 May 27; 95(10):1254-8.
      View in: PubMed
    12. Ashoor I, Najafian N, Korin Y, Reed EF, Mohanakumar T, Ikle D, Heeger PS, Lin M. Standardization and cross validation of alloreactive IFN? ELISPOT assays within the clinical trials in organ transplantation consortium. Am J Transplant. 2013 Jul; 13(7):1871-9.
      View in: PubMed
    13. van der Touw W, Cravedi P, Kwan WH, Paz-Artal E, Merad M, Heeger PS. Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells. J Immunol. 2013 Jun 15; 190(12):5921-5.
      View in: PubMed
    14. Khan MA, Maasch C, Vater A, Klussmann S, Morser J, Leung LL, Atkinson C, Tomlinson S, Heeger PS, Nicolls MR. Targeting complement component 5a promotes vascular integrity and limits airway remodeling. Proc Natl Acad Sci U S A. 2013 Apr 9; 110(15):6061-6.
      View in: PubMed
    15. Reid-Adam J, Yang N, Song Y, Cravedi P, Li XM, Heeger P. Immunosuppressive effects of the traditional Chinese herb Qu Mai on human alloreactive T cells. Am J Transplant. 2013 May; 13(5):1159-67.
      View in: PubMed
    16. Kwan WH, van der Touw W, Paz-Artal E, Li MO, Heeger PS. Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells. J Exp Med. 2013 Feb 11; 210(2):257-68.
      View in: PubMed
    17. Kwan WH, van der Touw W, Heeger PS. Complement regulation of T cell immunity. Immunol Res. 2012 Dec; 54(1-3):247-53.
      View in: PubMed
    18. Nair V, Heeger PS. Sequestration and suppression of anti-HLA antibodies by a failed kidney allograft. Clin J Am Soc Nephrol. 2012 Aug; 7(8):1209-10.
      View in: PubMed
    19. Kwan WH, Hashimoto D, Paz-Artal E, Ostrow K, Greter M, Raedler H, Medof ME, Merad M, Heeger PS. Antigen-presenting cell-derived complement modulates graft-versus-host disease. J Clin Invest. 2012 Jun 1; 122(6):2234-8.
      View in: PubMed
    20. Heeger PS, Dinavahi R. Transplant immunology for non-immunologist. Mt Sinai J Med. 2012 May-Jun; 79(3):376-87.
      View in: PubMed
    21. Nair V, Sawinski D, Akalin E, Friedlander R, Ebcioglu Z, Sehgal V, Dinavahi R, Khaim R, Ames S, Lerner S, Murphy B, Bromberg JS, Heeger PS, Schröppel B. Effect of high-dose intravenous immunoglobulin on anti-HLA antibodies in sensitized kidney transplant candidates. Clin Transplant. 2012 May-Jun; 26(3):E261-8.
      View in: PubMed
    22. Cravedi P, Heeger PS. Immunologic monitoring in transplantation revisited. Curr Opin Organ Transplant. 2012 Feb; 17(1):26-32.
      View in: PubMed
    23. Heeger PS, Kemper C. Novel roles of complement in T effector cell regulation. Immunobiology. 2012 Feb; 217(2):216-24.
      View in: PubMed
    24. Vieyra M, Leisman S, Raedler H, Kwan WH, Yang M, Strainic MG, Medof ME, Heeger PS. Complement regulates CD4 T-cell help to CD8 T cells required for murine allograft rejection. Am J Pathol. 2011 Aug; 179(2):766-74.
      View in: PubMed
    25. Kalache S, Dinavahi R, Pinney S, Mehrotra A, Cunningham MW, Heeger PS. Anticardiac myosin immunity and chronic allograft vasculopathy in heart transplant recipients. J Immunol. 2011 Jul 15; 187(2):1023-30.
      View in: PubMed
    26. Raedler H, Vieyra MB, Leisman S, Lakhani P, Kwan W, Yang M, Johnson K, Faas SJ, Tamburini P, Heeger PS. Anti-complement component C5 mAb synergizes with CTLA4Ig to inhibit alloreactive T cells and prolong cardiac allograft survival in mice. Am J Transplant. 2011 Jul; 11(7):1397-406.
      View in: PubMed
    27. Dinavahi R, George A, Tretin A, Akalin E, Ames S, Bromberg JS, Deboccardo G, Dipaola N, Lerner SM, Mehrotra A, Murphy BT, Nadasdy T, Paz-Artal E, Salomon DR, Schröppel B, Sehgal V, Sachidanandam R, Heeger PS. Antibodies reactive to non-HLA antigens in transplant glomerulopathy. J Am Soc Nephrol. 2011 Jun; 22(6):1168-78.
      View in: PubMed
    28. Hashimoto D, Chow A, Greter M, Saenger Y, Kwan WH, Leboeuf M, Ginhoux F, Ochando JC, Kunisaki Y, van Rooijen N, Liu C, Teshima T, Heeger PS, Stanley ER, Frenette PS, Merad M. Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation. J Exp Med. 2011 May 9; 208(5):1069-82.
      View in: PubMed
    29. Raedler H, Heeger PS. Complement regulation of T-cell alloimmunity. Curr Opin Organ Transplant. 2011 Feb; 16(1):54-60.
      View in: PubMed
    30. Sawinski D, Uribarri J, Peace D, Yao T, Wauhop P, Trzcinka P, Ostrow K, Poggio ED, Heeger PS. 25-OH-vitamin D deficiency and cellular alloimmunity as measured by panel of reactive T cell testing in dialysis patients. Am J Transplant. 2010 Oct; 10(10):2287-95.
      View in: PubMed
    31. Gurkan S, Luan Y, Dhillon N, Allam SR, Montague T, Bromberg JS, Ames S, Lerner S, Ebcioglu Z, Nair V, Dinavahi R, Sehgal V, Heeger P, Schroppel B, Murphy B. Immune reconstitution following rabbit antithymocyte globulin. Am J Transplant. 2010 Sep; 10(9):2132-41.
      View in: PubMed
    32. Heeger PS. A complementary approach to treating antibody-mediated transplant rejection. Kidney Int. 2010 Jul; 78(2):125-7.
      View in: PubMed
    33. Lin M, Yin N, Murphy B, Medof ME, Segerer S, Heeger PS, Schröppel B. Immune cell-derived c3 is required for autoimmune diabetes induced by multiple low doses of streptozotocin. Diabetes. 2010 Sep; 59(9):2247-52.
      View in: PubMed
    34. Schröppel B, Heeger PS. Gazing into a crystal ball to predict kidney transplant outcome. J Clin Invest. 2010 Jun; 120(6):1803-6.
      View in: PubMed
    35. Danziger-Isakov L, Cherkassky L, Siegel H, McManamon M, Kramer K, Budev M, Sawinski D, Augustine JJ, Hricik DE, Fairchild R, Heeger PS, Poggio ED. Effects of influenza immunization on humoral and cellular alloreactivity in humans. Transplantation. 2010 Apr 15; 89(7):838-44.
      View in: PubMed
    36. Bromberg JS, Heeger PS, Li XC. Evolving paradigms that determine the fate of an allograft. Am J Transplant. 2010 May; 10(5):1143-8.
      View in: PubMed
    37. Esposito A, Suedekum B, Liu J, An F, Lass J, Strainic MG, Lin F, Heeger P, Medof ME. Decay accelerating factor is essential for successful corneal engraftment. Am J Transplant. 2010 Mar; 10(3):527-34.
      View in: PubMed
    38. Vieyra MB, Heeger PS. Novel aspects of complement in kidney injury. Kidney Int. 2010 Mar; 77(6):495-9.
      View in: PubMed
    39. Dinavahi R, Heeger PS. T-cell immune monitoring in organ transplantation. Transplantation. 2009 Nov 27; 88(10):1157-8.
      View in: PubMed
    40. Raedler H, Yang M, Lalli PN, Medof ME, Heeger PS. Primed CD8(+) T-cell responses to allogeneic endothelial cells are controlled by local complement activation. Am J Transplant. 2009 Aug; 9(8):1784-95.
      View in: PubMed
    41. Lalli PN, Zhou W, Sacks S, Medof ME, Heeger PS. Locally produced and activated complement as a mediator of alloreactive T cells. Front Biosci (Schol Ed). 2009; 1:117-24.
      View in: PubMed
    42. Danziger-Isakov L, Heeger PS. Clinical utility of measuring T-cell immunity to CMV in transplant recipients. Am J Transplant. 2009 May; 9(5):987-8.
      View in: PubMed
    43. Krüger B, Krick S, Dhillon N, Lerner SM, Ames S, Bromberg JS, Lin M, Walsh L, Vella J, Fischereder M, Krämer BK, Colvin RB, Heeger PS, Murphy BT, Schröppel B. Donor Toll-like receptor 4 contributes to ischemia and reperfusion injury following human kidney transplantation. Proc Natl Acad Sci U S A. 2009 Mar 3; 106(9):3390-5.
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    44. Nickerson P, Heeger PS. Proteomic portrayal of transplant pathologies. J Am Soc Nephrol. 2009 Feb; 20(2):236-8.
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    45. Zang W, Lin M, Kalache S, Zhang N, Krüger B, Waaga-Gasser AM, Grimm M, Hancock W, Heeger P, Schröppel B, Murphy B. Inhibition of the alloimmune response through the generation of regulatory T cells by a MHC class II-derived peptide. J Immunol. 2008 Dec 1; 181(11):7499-506.
      View in: PubMed
    46. Keslar K, Rodriguez ER, Tan CD, Starling RC, Heeger PS. Complement gene expression in human cardiac allograft biopsies as a correlate of histologic grade of injury. Transplantation. 2008 Nov 15; 86(9):1319-21.
      View in: PubMed
    47. Pavlov V, Raedler H, Yuan S, Leisman S, Kwan WH, Lalli PN, Medof ME, Heeger PS. Donor deficiency of decay-accelerating factor accelerates murine T cell-mediated cardiac allograft rejection. J Immunol. 2008 Oct 1; 181(7):4580-9.
      View in: PubMed
    48. Augustine JJ, Poggio ED, Heeger PS, Hricik DE. Preferential benefit of antibody induction therapy in kidney recipients with high pretransplant frequencies of donor-reactive interferon-gamma enzyme-linked immunosorbent spots. Transplantation. 2008 Aug 27; 86(4):529-34.
      View in: PubMed
    49. Dinavahi R, Heeger PS. T-cell immune monitoring in organ transplantation. Curr Opin Organ Transplant. 2008 Aug; 13(4):419-24.
      View in: PubMed
    50. Lalli PN, Strainic MG, Yang M, Lin F, Medof ME, Heeger PS. Locally produced C5a binds to T cell-expressed C5aR to enhance effector T-cell expansion by limiting antigen-induced apoptosis. Blood. 2008 Sep 1; 112(5):1759-66.
      View in: PubMed
    51. Liu J, Lin F, Strainic MG, An F, Miller RH, Altuntas CZ, Heeger PS, Tuohy VK, Medof ME. IFN-gamma and IL-17 production in experimental autoimmune encephalomyelitis depends on local APC-T cell complement production. J Immunol. 2008 May 1; 180(9):5882-9.
      View in: PubMed
    52. Strainic MG, Liu J, Huang D, An F, Lalli PN, Muqim N, Shapiro VS, Dubyak GR, Heeger PS, Medof ME. Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells. Immunity. 2008 Mar; 28(3):425-35.
      View in: PubMed
    53. Lalli PN, Strainic MG, Lin F, Medof ME, Heeger PS. Decay accelerating factor can control T cell differentiation into IFN-gamma-producing effector cells via regulating local C5a-induced IL-12 production. J Immunol. 2007 Nov 1; 179(9):5793-802.
      View in: PubMed
    54. Akalin E, Dinavahi R, Dikman S, de Boccardo G, Friedlander R, Schroppel B, Sehgal V, Bromberg JS, Heeger P, Murphy B. Transplant glomerulopathy may occur in the absence of donor-specific antibody and C4d staining. Clin J Am Soc Nephrol. 2007 Nov; 2(6):1261-7.
      View in: PubMed
    55. Zhou W, Medof ME, Heeger PS, Sacks S. Graft-derived complement as a mediator of transplant injury. Curr Opin Immunol. 2007 Oct; 19(5):569-76.
      View in: PubMed
    56. Heeger PS. Frontiers in nephrology: tolerance. J Am Soc Nephrol. 2007 Aug; 18(8):2240-1.
      View in: PubMed
    57. Poggio ED, Augustine JJ, Clemente M, Danzig JM, Volokh N, Zand MS, Hricik DE, Heeger PS. Pretransplant cellular alloimmunity as assessed by a panel of reactive T cells assay correlates with acute renal graft rejection. Transplantation. 2007 Apr 15; 83(7):847-52.
      View in: PubMed
    58. Yonkers NL, Rodriguez B, Milkovich KA, Asaad R, Lederman MM, Heeger PS, Anthony DD. TLR ligand-dependent activation of naive CD4 T cells by plasmacytoid dendritic cells is impaired in hepatitis C virus infection. J Immunol. 2007 Apr 1; 178(7):4436-44.
      View in: PubMed
    59. Augustine JJ, Poggio ED, Clemente M, Aeder MI, Bodziak KA, Schulak JA, Heeger PS, Hricik DE. Hemodialysis vintage, black ethnicity, and pretransplantation antidonor cellular immunity in kidney transplant recipients. J Am Soc Nephrol. 2007 May; 18(5):1602-6.
      View in: PubMed
    60. Issa N, Stephany B, Fatica R, Nurko S, Krishnamurthi V, Goldfarb DA, Braun WE, Dennis VW, Heeger PS, Poggio ED. Donor factors influencing graft outcomes in live donor kidney transplantation. Transplantation. 2007 Mar 15; 83(5):593-9.
      View in: PubMed
    61. Poggio ED, Hila S, Stephany B, Fatica R, Krishnamurthi V, del Bosque C, Goldfarb D, Herts B, Dennis VW, Heeger PS, Braun W. Donor kidney volume and outcomes following live donor kidney transplantation. Am J Transplant. 2006 Mar; 6(3):616-24.
      View in: PubMed
    62. Valujskikh A, Zhang Q, Heeger PS. CD8 T cells specific for a donor-derived, self-restricted transplant antigen are nonpathogenic bystanders after vascularized heart transplantation in mice. J Immunol. 2006 Feb 15; 176(4):2190-6.
      View in: PubMed
    63. Zhang Q, Chen Y, Fairchild RL, Heeger PS, Valujskikh A. Lymphoid sequestration of alloreactive memory CD4 T cells promotes cardiac allograft survival. J Immunol. 2006 Jan 15; 176(2):770-7.
      View in: PubMed
    64. Poggio ED, Clemente M, Hricik DE, Heeger PS. Panel of reactive T cells as a measurement of primed cellular alloimmunity in kidney transplant candidates. J Am Soc Nephrol. 2006 Feb; 17(2):564-72.
      View in: PubMed
    65. Poggio ED, Roddy M, Riley J, Clemente M, Hricik DE, Starling R, Young JB, Gus B, Yamani MH, Heeger PS. Analysis of immune markers in human cardiac allograft recipients and association with coronary artery vasculopathy. J Heart Lung Transplant. 2005 Oct; 24(10):1606-13.
      View in: PubMed
    66. Roddy M, Clemente M, Poggio ED, Bukowski R, Thakkar S, Waxenecker G, Loibner H, Himmler G, Hricik DE, Heeger PS. Heterogeneous alterations in human alloimmunity associated with immunization. Transplantation. 2005 Aug 15; 80(3):297-302.
      View in: PubMed
    67. Augustine JJ, Siu DS, Clemente MJ, Schulak JA, Heeger PS, Hricik DE. Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients. Am J Transplant. 2005 Aug; 5(8):1971-5.
      View in: PubMed
    68. Bagai R, Valujskikh A, Canaday DH, Bailey E, Lalli PN, Harding CV, Heeger PS. Mouse endothelial cells cross-present lymphocyte-derived antigen on class I MHC via a TAP1- and proteasome-dependent pathway. J Immunol. 2005 Jun 15; 174(12):7711-5.
      View in: PubMed
    69. Heeger PS, Lalli PN, Lin F, Valujskikh A, Liu J, Muqim N, Xu Y, Medof ME. Decay-accelerating factor modulates induction of T cell immunity. J Exp Med. 2005 May 16; 201(10):1523-30.
      View in: PubMed
    70. Schenk S, Kish DD, He C, El-Sawy T, Chiffoleau E, Chen C, Chen C, Wu Z, Sandner S, Gorbachev AV, Fukamachi K, Heeger PS, Sayegh MH, Turka LA, Fairchild RL. Alloreactive T cell responses and acute rejection of single class II MHC-disparate heart allografts are under strict regulation by CD4+ CD25+ T cells. J Immunol. 2005 Mar 15; 174(6):3741-8.
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    71. Heeger PS. Amnion and chorion cells as therapeutic agents for transplantation and tissue regeneration: a field in its infancy. Transplantation. 2004 Nov 27; 78(10):1411-2.
      View in: PubMed
    72. Poggio ED, Clemente M, Riley J, Roddy M, Greenspan NS, Dejelo C, Najafian N, Sayegh MH, Hricik DE, Heeger PS. Alloreactivity in renal transplant recipients with and without chronic allograft nephropathy. J Am Soc Nephrol. 2004 Jul; 15(7):1952-60.
      View in: PubMed
    73. He C, Heeger PS. CD8 T cells can reject major histocompatibility complex class I-deficient skin allografts. Am J Transplant. 2004 May; 4(5):698-704.
      View in: PubMed
    74. Chen Y, Heeger PS, Valujskikh A. In vivo helper functions of alloreactive memory CD4+ T cells remain intact despite donor-specific transfusion and anti-CD40 ligand therapy. J Immunol. 2004 May 1; 172(9):5456-66.
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    75. Chen Y, Demir Y, Valujskikh A, Heeger PS. Antigen location contributes to the pathological features of a transplanted heart graft. Am J Pathol. 2004 Apr; 164(4):1407-15.
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    76. Bayer J, Gomer A, Demir Y, Amano H, Kish DD, Fairchild R, Heeger PS. Effects of green tea polyphenols on murine transplant-reactive T cell immunity. Clin Immunol. 2004 Jan; 110(1):100-8.
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    77. He C, Schenk S, Zhang Q, Valujskikh A, Bayer J, Fairchild RL, Heeger PS. Effects of T cell frequency and graft size on transplant outcome in mice. J Immunol. 2004 Jan 1; 172(1):240-7.
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    78. Chen Y, Demir Y, Valujskikh A, Heeger PS. The male minor transplantation antigen preferentially activates recipient CD4+ T cells through the indirect presentation pathway in vivo. J Immunol. 2003 Dec 15; 171(12):6510-8.
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    79. Heeger PS. What's new and what's hot in transplantation: basic science ATC 2003. Am J Transplant. 2003 Dec; 3(12):1474-80.
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    80. Valujskikh A, Heeger PS. Emerging roles of endothelial cells in transplant rejection. Curr Opin Immunol. 2003 Oct; 15(5):493-8.
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    81. Demir Y, Chen Y, Metz C, Renz H, Heeger PS. Cardiac allograft rejection in the absence of macrophage migration inhibitory factor. Transplantation. 2003 Jul 15; 76(1):244-7.
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    82. Hricik DE, Rodriguez V, Riley J, Bryan K, Tary-Lehmann M, Greenspan N, Dejelo C, Schulak JA, Heeger PS. Enzyme linked immunosorbent spot (ELISPOT) assay for interferon-gamma independently predicts renal function in kidney transplant recipients. Am J Transplant. 2003 Jul; 3(7):878-84.
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    83. Heeger PS. T-cell allorecognition and transplant rejection: a summary and update. Am J Transplant. 2003 May; 3(5):525-33.
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    84. Illigens BM, Yamada A, Fedoseyeva EV, Anosova N, Boisgerault F, Valujskikh A, Heeger PS, Sayegh MH, Boehm B, Benichou G. The relative contribution of direct and indirect antigen recognition pathways to the alloresponse and graft rejection depends upon the nature of the transplant. Hum Immunol. 2002 Oct; 63(10):912-25.
      View in: PubMed
    85. Gebauer BS, Hricik DE, Atallah A, Bryan K, Riley J, Tary-Lehmann M, Greenspan NS, Dejelo C, Boehm BO, Hering BJ, Heeger PS. Evolution of the enzyme-linked immunosorbent spot assay for post-transplant alloreactivity as a potentially useful immune monitoring tool. Am J Transplant. 2002 Oct; 2(9):857-66.
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    86. Pantenburg B, Heinzel F, Das L, Heeger PS, Valujskikh A. T cells primed by Leishmania major infection cross-react with alloantigens and alter the course of allograft rejection. J Immunol. 2002 Oct 1; 169(7):3686-93.
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    87. Valujskikh A, Lantz O, Celli S, Matzinger P, Heeger PS. Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway. Nat Immunol. 2002 Sep; 3(9):844-51.
      View in: PubMed
    88. Fedoseyeva EV, Kishimoto K, Rolls HK, Illigens BM, Dong VM, Valujskikh A, Heeger PS, Sayegh MH, Benichou G. Modulation of tissue-specific immune response to cardiac myosin can prolong survival of allogeneic heart transplants. J Immunol. 2002 Aug 1; 169(3):1168-74.
      View in: PubMed
    89. Valujskikh A, Pantenburg B, Heeger PS. Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice. Am J Transplant. 2002 Jul; 2(6):501-9.
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    90. Anthony DD, Valdez H, Post AB, Carlson NL, Heeger PS, Lehmann PV. Comprehensive determinant mapping of the hepatitis C-specific CD8 cell repertoire reveals unpredicted immune hierarchy. Clin Immunol. 2002 Jun; 103(3 Pt 1):264-76.
      View in: PubMed
    91. Valdez H, Carlson NL, Post AB, Asaad R, Heeger PS, Lederman MM, Lehmann PV, Anthony DD. HIV long-term non-progressors maintain brisk CD8 T cell responses to other viral antigens. AIDS. 2002 May 24; 16(8):1113-8.
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    92. Valujskikh A, Fedoseyeva E, Benichou G, Heeger PS. Development of autoimmunity after skin graft rejection via an indirect alloresponse. Transplantation. 2002 Apr 15; 73(7):1130-7.
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    93. Heeger PS, Hricik D. Immune monitoring in kidney transplant recipients revisited. J Am Soc Nephrol. 2002 Jan; 13(1):288-90.
      View in: PubMed
    94. Hou G, Valujskikh A, Bayer J, Stavitsky AB, Metz C, Heeger PS. In vivo blockade of macrophage migration inhibitory factor prevents skin graft destruction after indirect allorecognition. Transplantation. 2001 Dec 27; 72(12):1890-7.
      View in: PubMed
    95. Wang D, Gong X, Heeger PS, Rininsland F, Bazan GC, Heeger AJ. Biosensors from conjugated polyelectrolyte complexes. Proc Natl Acad Sci U S A. 2002 Jan 8; 99(1):49-53.
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    96. Hricik DE, Heeger PS. Minimization of immunosuppression in kidney transplantation. The need for immune monitoring. Transplantation. 2001 Oct 27; 72(8 Suppl):S32-5.
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    97. Thomson AW, Mazariegos GV, Reyes J, Donnenberg VS, Donnenberg AD, Bentlejewski C, Zahorchak AF, O'Connell PJ, Fung JJ, Jankowska-Gan E, Burlingham WJ, Heeger PS, Zeevi A. Monitoring the patient off immunosuppression. Conceptual framework for a proposed tolerance assay study in liver transplant recipients. Transplantation. 2001 Oct 27; 72(8 Suppl):S13-22.
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    98. Valujskikh A, VanBuskirk AM, Orosz CG, Heeger PS. A role for TGFbeta and B cells in immunologic tolerance after intravenous injection of soluble antigen. Transplantation. 2001 Aug 27; 72(4):685-93.
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    99. Anthony DD, Heeger PS, Haqqi TM. Immunization with TCR Vbeta10 peptide reduces the frequency of type-II collagen-specific Th1 type T cells in BUB/BnJ (H-2q) mice. Clin Exp Rheumatol. 2001 Jul-Aug; 19(4):385-94.
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    100. Anthony DD, Post AB, Valdez H, Peterson DL, Murphy M, Heeger PS. ELISPOT analysis of hepatitis C virus protein-specific IFN-gamma-producing peripheral blood lymphocytes in infected humans with and without cirrhosis. Clin Immunol. 2001 May; 99(2):232-40.
      View in: PubMed
    101. Baron ED, Heeger PS, Hricik DE, Schulak JA, Tary-Lehmann M, Stevens SR. Immunomodulatory effect of extracorporeal photopheresis after successful treatment of resistant renal allograft rejection. Photodermatol Photoimmunol Photomed. 2001 Apr; 17(2):79-82.
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    102. Valujskikh A, Hartig C, Heeger PS. Indirectly primed CD8+ T cells are a prominent component of the allogeneic T-cell repertoire after skin graft rejection in mice. Transplantation. 2001 Feb 15; 71(3):418-21.
      View in: PubMed
    103. Gorbachev AV, Heeger PS, Fairchild RL. CD4+ and CD8+ T cell priming for contact hypersensitivity occurs independently of CD40-CD154 interactions. J Immunol. 2001 Feb 15; 166(4):2323-32.
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    104. Valdez H, Anthony D, Farukhi F, Patki A, Salkowitz J, Heeger P, Peterson DL, Post AB, Asaad R, Lederman MM. Immune responses to hepatitis C and non-hepatitis C antigens in hepatitis C virus infected and HIV-1 coinfected patients. AIDS. 2000 Oct 20; 14(15):2239-46.
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    105. Heeger PS, Valujskikh A, Lehmann PV. Comprehensive assessment of determinant specificity, frequency, and cytokine signature of the primed CD8 cell repertoire induced by a minor transplantation antigen. J Immunol. 2000 Aug 1; 165(3):1278-84.
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    106. Truett GE, Heeger P, Mynatt RL, Truett AA, Walker JA, Warman ML. Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT). Biotechniques. 2000 Jul; 29(1):52, 54.
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    107. Heeger PS, Forsthuber T, Shive C, Biekert E, Genain C, Hofstetter HH, Karulin A, Lehmann PV. Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant. J Immunol. 2000 Jun 1; 164(11):5771-81.
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    108. Engeman TM, Gorbachev AV, Gladue RP, Heeger PS, Fairchild RL. Inhibition of functional T cell priming and contact hypersensitivity responses by treatment with anti-secondary lymphoid chemokine antibody during hapten sensitization. J Immunol. 2000 May 15; 164(10):5207-14.
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    109. Valujskikh A, Heeger PS. CD4+ T cells responsive through the indirect pathway can mediate skin graft rejection in the absence of interferon-gamma. Transplantation. 2000 Mar 15; 69(5):1016-9.
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    110. Hartig CV, Haller GW, Sachs DH, Kuhlenschmidt S, Heeger PS. Naturally developing memory T cell xenoreactivity to swine antigens in human peripheral blood lymphocytes. J Immunol. 2000 Mar 1; 164(5):2790-6.
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    111. Heeger PS, Heeger AJ. Making sense of polymer-based biosensors. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12219-21.
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    112. Valujskikh A, Matesic D, Heeger PS. Characterization and manipulation of T cell immunity to skin grafts expressing a transgenic minor antigen. Transplantation. 1999 Oct 15; 68(7):1029-36.
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    113. Heeger PS, Greenspan NS, Kuhlenschmidt S, Dejelo C, Hricik DE, Schulak JA, Tary-Lehmann M. Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J Immunol. 1999 Aug 15; 163(4):2267-75.
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    114. Yip HC, Karulin AY, Tary-Lehmann M, Hesse MD, Radeke H, Heeger PS, Trezza RP, Heinzel FP, Forsthuber T, Lehmann PV. Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response. J Immunol. 1999 Apr 1; 162(7):3942-9.
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    115. Benichou G, Valujskikh A, Heeger PS. Contributions of direct and indirect T cell alloreactivity during allograft rejection in mice. J Immunol. 1999 Jan 1; 162(1):352-8.
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    116. Matesic D, Valujskikh A, Pearlman E, Higgins AW, Gilliam AC, Heeger PS. Type 2 immune deviation has differential effects on alloreactive CD4+ and CD8+ T cells. J Immunol. 1998 Nov 15; 161(10):5236-44.
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    117. Benichou G, Malloy KM, Tam RC, Heeger PS, Fedoseyeva EV. The presentation of self and allogeneic MHC peptides to T lymphocytes. Hum Immunol. 1998 Sep; 59(9):540-8.
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    118. Tary-Lehmann M, Hricik DE, Justice AC, Potter NS, Heeger PS. Enzyme-linked immunosorbent assay spot detection of interferon-gamma and interleukin 5-producing cells as a predictive marker for renal allograft failure. Transplantation. 1998 Jul 27; 66(2):219-24.
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    119. Matesic D, Lehmann PV, Heeger PS. High-resolution characterization of cytokine-producing alloreactivity in naive and allograft-primed mice. Transplantation. 1998 Apr 15; 65(7):906-14.
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    120. Valujskikh A, Matesic D, Gilliam A, Anthony D, Haqqi TM, Heeger PS. T cells reactive to a single immunodominant self-restricted allopeptide induce skin graft rejection in mice. J Clin Invest. 1998 Mar 15; 101(6):1398-407.
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    121. Xu H, Heeger PS, Fairchild RL. Distinct roles for B7-1 and B7-2 determinants during priming of effector CD8+ Tc1 and regulatory CD4+ Th2 cells for contact hypersensitivity. J Immunol. 1997 Nov 1; 159(9):4217-26.
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    122. Lehmann PV, Matesic D, Benichou G, Heeger PS. Induction of T helper 2 immunity to an immunodominant allopeptide. Transplantation. 1997 Jul 27; 64(2):292-6.
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    123. Heeger PS, Smoyer WE, Jones M, Hopfer S, Neilson EG. Heterogeneous T cell receptor V beta gene repertoire in murine interstitial nephritis. Kidney Int. 1996 May; 49(5):1222-30.
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    124. Heeger PS, Smoyer WE, Saad T, Albert S, Kelly CJ, Neilson EG. Molecular analysis of the helper T cell response in murine interstitial nephritis. T cells recognizing an immunodominant epitope use multiple T cell receptor V beta genes with similarities across CDR3. J Clin Invest. 1994 Nov; 94(5):2084-92.
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    125. Heeger PS, Neilson EG. Overcoming tolerance in autoimmune renal disease. Curr Opin Nephrol Hypertens. 1994 Mar; 3(2):123-32.
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    126. Danoff TM, Lalley PA, Chang YS, Heeger PS, Neilson EG. Cloning, genomic organization, and chromosomal localization of the Scya5 gene encoding the murine chemokine RANTES. J Immunol. 1994 Feb 1; 152(3):1182-9.
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    127. Heeger P, Wolf G, Meyers C, Sun MJ, O'Farrell SC, Krensky AM, Neilson EG. Isolation and characterization of cDNA from renal tubular epithelium encoding murine Rantes. Kidney Int. 1992 Jan; 41(1):220-5.
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    128. Szerlip HM, Heeger P, Feldman GM. Comparison between acetate and bicarbonate dialysis for the treatment of lithium intoxication. Am J Nephrol. 1992; 12(1-2):116-20.
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    129. Krishna GG, Newell G, Miller E, Heeger P, Smith R, Polansky M, Kapoor S, Hoeldtke R. Protein-induced glomerular hyperfiltration: role of hormonal factors. Kidney Int. 1988 Feb; 33(2):578-83.
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    130. Friedman AC, Ramchandani P, Black M, Caroline DF, Radecki PD, Heeger P. Magnetic resonance imaging diagnosis of Budd-Chiari syndrome. Gastroenterology. 1986 Nov; 91(5):1289-95.
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    131. Heeger PS, Backstrom JT. Heparin flushes and thrombocytopenia. Ann Intern Med. 1986 Jul; 105(1):143.
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    132. Fleisher G, Heeger P, Topf P. Hemophilus influenzae cellulitis. Am J Emerg Med. 1983 Nov; 1(3):274-7.
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    133. Heeger P, Rosenbloom J. Biosynthesis of tropoelastin by elastic cartilage. Connect Tissue Res. 1980; 8(1):21-5.
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