Keywords
Last Name
Institution

Larry J. Siever

TitlePROFESSOR
InstitutionMount Sinai
DepartmentPsychiatry
Address5 East 98th Street
Box 1230
New York NY 10029
Phone212-774-1722
Fax718-364-3576

     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. McGurk SR, Mueser KT, Mischel R, Adams R, Harvey PD, McClure MM, Look AE, Leung WW, Siever LJ. Vocational functioning in schizotypal and paranoid personality disorders. Psychiatry Res. 2013 Dec 15; 210(2):498-504.
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    2. Siever L. Paranoid case vignette. Personal Ment Health. 2013 Aug; 7(3):262-3.
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    3. Ripoll LH, Zaki J, Perez-Rodriguez MM, Snyder R, Strike KS, Boussi A, Bartz JA, Ochsner KN, Siever LJ, New AS. Empathic accuracy and cognition in schizotypal personality disorder. Psychiatry Res. 2013 Nov 30; 210(1):232-41.
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    4. Greenwood TA, Swerdlow NR, Gur RE, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Ray A, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Light GA, Braff DL. Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry. 2013 May 1; 170(5):521-32.
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    5. Ripoll LH, Snyder R, Steele H, Siever LJ. The neurobiology of empathy in borderline personality disorder. Curr Psychiatry Rep. 2013 Mar; 15(3):344.
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    6. Calkins ME, Ray A, Gur RC, Freedman R, Green MF, Greenwood TA, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar C, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL, Lazzeroni LC, Gur RE. Sex differences in familiality effects on neurocognitive performance in schizophrenia. Biol Psychiatry. 2013 May 15; 73(10):976-84.
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    7. McClure MM, Harvey PD, Bowie CR, Iacoviello B, Siever LJ. Functional outcomes, functional capacity, and cognitive impairment in schizotypal personality disorder. Schizophr Res. 2013 Mar; 144(1-3):146-50.
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    8. Triebwasser J, Chemerinski E, Roussos P, Siever LJ. Schizoid personality disorder. J Pers Disord. 2012 Dec; 26(6):919-26.
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    9. Roussos P, Katsel P, Davis KL, Siever LJ, Haroutunian V. A system-level transcriptomic analysis of schizophrenia using postmortem brain tissue samples. Arch Gen Psychiatry. 2012 Dec; 69(12):1205-13.
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    10. Chemerinski E, Byne W, Kolaitis JC, Glanton CF, Canfield EL, Newmark RE, Haznedar MM, Novakovic V, Chu KW, Siever LJ, Hazlett EA. Larger putamen size in antipsychotic-naïve individuals with schizotypal personality disorder. Schizophr Res. 2013 Jan; 143(1):158-64.
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    11. Keyes KM, Eaton NR, Krueger RF, Skodol AE, Wall MM, Grant B, Siever LJ, Hasin DS. Thought disorder in the meta-structure of psychopathology. Psychol Med. 2013 Aug; 43(8):1673-83.
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    12. Roussos P, Katsel P, Davis KL, Giakoumaki SG, Lencz T, Malhotra AK, Siever LJ, Bitsios P, Haroutunian V. Convergent findings for abnormalities of the NF-?B signaling pathway in schizophrenia. Neuropsychopharmacology. 2013 Feb; 38(3):533-9.
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    13. New AS, aan het Rot M, Ripoll LH, Perez-Rodriguez MM, Lazarus S, Zipursky E, Weinstein SR, Koenigsberg HW, Hazlett EA, Goodman M, Siever LJ. Empathy and alexithymia in borderline personality disorder: clinical and laboratory measures. J Pers Disord. 2012 Oct; 26(5):660-75.
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    14. Hazlett EA, Collazo T, Zelmanova Y, Entis JJ, Chu KW, Goldstein KE, Roussos P, Haznedar MM, Koenigsberg HW, New AS, Buchsbaum MS, Hershowitz JP, Siever LJ, Byne W. Anterior limb of the internal capsule in schizotypal personality disorder: fiber-tract counting, volume, and anisotropy. Schizophr Res. 2012 Nov; 141(2-3):119-27.
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    15. Roussos P, Bitsios P, Giakoumaki SG, McClure MM, Hazlett EA, New AS, Siever LJ. CACNA1C as a risk factor for schizotypal personality disorder and schizotypy in healthy individuals. Psychiatry Res. 2013 Mar 30; 206(1):122-3.
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    16. Chemerinski E, Triebwasser J, Roussos P, Siever LJ. Schizotypal personality disorder. J Pers Disord. 2013 Oct; 27(5):652-79.
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    17. Triebwasser J, Chemerinski E, Roussos P, Siever LJ. Paranoid personality disorder. J Pers Disord. 2013 Dec; 27(6):795-805.
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    18. Koenigsberg HW, Yuan P, Diaz GA, Guerreri S, Dorantes C, Mayson S, Zamfirescu C, New AS, Goodman M, Manji HK, Siever LJ. Platelet protein kinase C and brain-derived neurotrophic factor levels in borderline personality disorder patients. Psychiatry Res. 2012 Sep 30; 199(2):92-7.
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    19. Hazlett EA, Zhang J, New AS, Zelmanova Y, Goldstein KE, Haznedar MM, Meyerson D, Goodman M, Siever LJ, Chu KW. Potentiated amygdala response to repeated emotional pictures in borderline personality disorder. Biol Psychiatry. 2012 Sep 15; 72(6):448-56.
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    20. Flory JD, Yehuda R, Passarelli V, Siever LJ. Joint Effect of Childhood Abuse and Family History of Major Depressive Disorder on Rates of PTSD in People with Personality Disorders. Depress Res Treat. 2012; 2012:350461.
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    21. Perez-Rodriguez MM, Hazlett EA, Rich EL, Ripoll LH, Weiner DM, Spence N, Goodman M, Koenigsberg HW, Siever LJ, New AS. Striatal activity in borderline personality disorder with comorbid intermittent explosive disorder: sex differences. J Psychiatr Res. 2012 Jun; 46(6):797-804.
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    22. Lyddon R, Dwork AJ, Keddache M, Siever LJ, Dracheva S. Serotonin 2c receptor RNA editing in major depression and suicide. World J Biol Psychiatry. 2013 Dec; 14(8):590-601.
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    23. Bespalova IN, Angelo GW, Ritter BP, Hunter J, Reyes-Rabanillo ML, Siever LJ, Silverman JM. Genetic variations in the ADAMTS12 gene are associated with schizophrenia in Puerto Rican patients of Spanish descent. Neuromolecular Med. 2012 Mar; 14(1):53-64.
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    24. Gabbard GO, Schmahl C, Siever LJ, Iskander EG. Personality disorders. Handb Clin Neurol. 2012; 106:463-75.
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    25. Roussos P, Katsel P, Davis KL, Bitsios P, Giakoumaki SG, Jogia J, Rozsnyai K, Collier D, Frangou S, Siever LJ, Haroutunian V. Molecular and genetic evidence for abnormalities in the nodes of Ranvier in schizophrenia. Arch Gen Psychiatry. 2012 Jan; 69(1):7-15.
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    26. Goodman M, Siever LJ. Hypermentalization in adolescents with borderline personality traits: extending the conceptual framework to younger ages. J Am Acad Child Adolesc Psychiatry. 2011 Jun; 50(6):536-7.
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    27. Mann SL, Hazlett EA, Byne W, Hof PR, Buchsbaum MS, Cohen BH, Goldstein KE, Haznedar MM, Mitsis EM, Siever LJ, Chu KW. Anterior and posterior cingulate cortex volume in healthy adults: effects of aging and gender differences. Brain Res. 2011 Jul 15; 1401:18-29.
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    28. Harvey PD, McClure MM, Patterson TL, McGrath JA, Pulver AE, Bowie CR, Siever LJ. Impairment in functional capacity as an endophenotype candidate in severe mental illness. Schizophr Bull. 2012 Nov; 38(6):1318-26.
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    29. Greenwood TA, Lazzeroni LC, Murray SS, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Gur RE, Gur RC, Hardiman G, Kelsoe JR, Leonard S, Light GA, Nuechterlein KH, Olincy A, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Freedman R, Braff DL. Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry. 2011 Sep; 168(9):930-46.
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    30. Skodol AE, Bender DS, Morey LC, Clark LA, Oldham JM, Alarcon RD, Krueger RF, Verheul R, Bell CC, Siever LJ. Personality disorder types proposed for DSM-5. J Pers Disord. 2011 Apr; 25(2):136-69.
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    31. Ripoll LH, Triebwasser J, Siever LJ. Evidence-based pharmacotherapy for personality disorders. Int J Neuropsychopharmacol. 2011 Oct; 14(9):1257-88.
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    32. Stone WS, Giuliano AJ, Tsuang MT, Braff DL, Cadenhead KS, Calkins ME, Dobie DJ, Faraone SV, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Roe AH, Schork NJ, Siever LJ, Silverman JM, Swerdlow NR, Thomas AR, Tsuang DW, Turetsky BI, Seidman LJ. Group and site differences on the California Verbal Learning Test in persons with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia (COGS). Schizophr Res. 2011 May; 128(1-3):102-10.
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    33. Katsel P, Byne W, Roussos P, Tan W, Siever L, Haroutunian V. Astrocyte and glutamate markers in the superficial, deep, and white matter layers of the anterior cingulate gyrus in schizophrenia. Neuropsychopharmacology. 2011 May; 36(6):1171-7.
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    34. Hazlett EA, Goldstein KE, Tajima-Pozo K, Speidel ER, Zelmanova Y, Entis JJ, Silverman JM, New AS, Koenigsberg HW, Haznedar MM, Byne W, Siever LJ. Cingulate and temporal lobe fractional anisotropy in schizotypal personality disorder. Neuroimage. 2011 Apr 1; 55(3):900-8.
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    35. Skodol AE, Bender DS, Oldham JM, Clark LA, Morey LC, Verheul R, Krueger RF, Siever LJ. Proposed changes in personality and personality disorder assessment and diagnosis for DSM-5 Part II: Clinical application. Personal Disord. 2011 Jan; 2(1):23-40.
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    36. Skodol AE, Clark LA, Bender DS, Krueger RF, Morey LC, Verheul R, Alarcon RD, Bell CC, Siever LJ, Oldham JM. Proposed changes in personality and personality disorder assessment and diagnosis for DSM-5 Part I: Description and rationale. Personal Disord. 2011 Jan; 2(1):4-22.
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    37. Lyddon R, Cuppen E, Haroutunian V, Siever LJ, Dracheva S. No link of serotonin 2C receptor editing to serotonin transporter genotype. Neuroreport. 2010 Dec 8; 21(17):1080-4.
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    38. Goldstein KE, Hazlett EA, Savage KR, Berlin HA, Hamilton HK, Zelmanova Y, Look AE, Koenigsberg HW, Mitsis EM, Tang CY, McNamara M, Siever LJ, Cohen BH, New AS. Dorso- and ventro-lateral prefrontal volume and spatial working memory in schizotypal personality disorder. Behav Brain Res. 2011 Apr 15; 218(2):335-40.
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    39. Mitropoulou V, Friedman L, Zegarelli G, Wajnberg S, Meshberg J, Silverman JM, Siever LJ. Eye tracking performance and the boundaries of the schizophrenia spectrum. Psychiatry Res. 2011 Mar 30; 186(1):18-22.
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    40. Rosell DR, Thompson JL, Slifstein M, Xu X, Frankle WG, New AS, Goodman M, Weinstein SR, Laruelle M, Abi-Dargham A, Siever LJ. Increased serotonin 2A receptor availability in the orbitofrontal cortex of physically aggressive personality disordered patients. Biol Psychiatry. 2010 Jun 15; 67(12):1154-62.
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    41. Kent BW, Weinstein ZA, Passarelli V, Chen Y, Siever LJ. Deficient visual sensitivity in schizotypal personality disorder. Schizophr Res. 2011 Apr; 127(1-3):144-50.
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    42. Perez-Rodriguez MM, Weinstein S, New AS, Bevilacqua L, Yuan Q, Zhou Z, Hodgkinson C, Goodman M, Koenigsberg HW, Goldman D, Siever LJ. Tryptophan-hydroxylase 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy controls. J Psychiatr Res. 2010 Nov; 44(15):1075-81.
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    43. Olincy A, Braff DL, Adler LE, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Wagner BD, Freedman R. Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia. Schizophr Res. 2010 Jun; 119(1-3):175-82.
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    44. Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Meichle SP, Millard SP, Mintz J, Nuechterlein KH, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang MT, Turetsky BI, Tsuang DW. Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study. Psychophysiology. 2010 Sep; 47(5):846-56.
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    45. Goodman M, Patil U, Triebwasser J, Diamond E, Hiller A, Hoffman P, Goldberg S, Koenigsberg H, Siever L, New A. Parental viewpoints of trajectories to borderline personality disorder in female offspring. J Pers Disord. 2010 Apr; 24(2):204-16.
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    46. Koenigsberg HW, Fan J, Ochsner KN, Liu X, Guise K, Pizzarello S, Dorantes C, Tecuta L, Guerreri S, Goodman M, New A, Flory J, Siever LJ. Neural correlates of using distancing to regulate emotional responses to social situations. Neuropsychologia. 2010 May; 48(6):1813-22.
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    47. McClure MM, Harvey PD, Goodman M, Triebwasser J, New A, Koenigsberg HW, Sprung LJ, Flory JD, Siever LJ. Pergolide treatment of cognitive deficits associated with schizotypal personality disorder: continued evidence of the importance of the dopamine system in the schizophrenia spectrum. Neuropsychopharmacology. 2010 May; 35(6):1356-62.
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    48. Steele H, Siever L. An attachment perspective on borderline personality disorder: advances in gene-environment considerations. Curr Psychiatry Rep. 2010 Feb; 12(1):61-7.
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    49. Goodman M, New AS, Triebwasser J, Collins KA, Siever L. Phenotype, endophenotype, and genotype comparisons between borderline personality disorder and major depressive disorder. J Pers Disord. 2010 Feb; 24(1):38-59.
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    50. Stanley B, Siever LJ. The interpersonal dimension of borderline personality disorder: toward a neuropeptide model. Am J Psychiatry. 2010 Jan; 167(1):24-39.
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    51. New AS, Hazlett EA, Newmark RE, Zhang J, Triebwasser J, Meyerson D, Lazarus S, Trisdorfer R, Goldstein KE, Goodman M, Koenigsberg HW, Flory JD, Siever LJ, Buchsbaum MS. Laboratory induced aggression: a positron emission tomography study of aggressive individuals with borderline personality disorder. Biol Psychiatry. 2009 Dec 15; 66(12):1107-14.
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    52. Koenigsberg HW, Fan J, Ochsner KN, Liu X, Guise KG, Pizzarello S, Dorantes C, Guerreri S, Tecuta L, Goodman M, New A, Siever LJ. Neural correlates of the use of psychological distancing to regulate responses to negative social cues: a study of patients with borderline personality disorder. Biol Psychiatry. 2009 Nov 1; 66(9):854-63.
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    53. McClure MM, Koenigsberg HW, Reynolds D, Goodman M, New A, Trestman R, Silverman J, Harvey PD, Siever LJ. The effects of risperidone on the cognitive performance of individuals with schizotypal personality disorder. J Clin Psychopharmacol. 2009 Aug; 29(4):396-8.
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    54. Goldstein KE, Hazlett EA, New AS, Haznedar MM, Newmark RE, Zelmanova Y, Passarelli V, Weinstein SR, Canfield EL, Meyerson DA, Tang CY, Buchsbaum MS, Siever LJ. Smaller superior temporal gyrus volume specificity in schizotypal personality disorder. Schizophr Res. 2009 Jul; 112(1-3):14-23.
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    55. Goodman M, Hazlett EA, New AS, Koenigsberg HW, Siever L. Quieting the affective storm of borderline personality disorder. Am J Psychiatry. 2009 May; 166(5):522-8.
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    56. Koenigsberg HW, Siever LJ, Lee H, Pizzarello S, New AS, Goodman M, Cheng H, Flory J, Prohovnik I. Neural correlates of emotion processing in borderline personality disorder. Psychiatry Res. 2009 Jun 30; 172(3):192-9.
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    57. Siever LJ, Weinstein LN. The neurobiology of personality disorders: implications for psychoanalysis. J Am Psychoanal Assoc. 2009 Apr; 57(2):361-98.
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    58. Freedman R, Lewis DA, Michels R, Pine DS, Schultz SK, Tamminga CA, Andreasen NC, Brady KT, Brent DA, Brzustowicz L, Carter CS, Eisenberg L, Goldman H, Javitt DC, Leibenluft E, Lieberman JA, Milrod B, Oquendo MA, Rosenbaum JF, Rush AJ, Siever LJ, Suppes P, Weissman MM, Roy MD, Scully JH, Yager J. Conflict of interest-- an issue for every psychiatrist. Am J Psychiatry. 2009 Mar; 166(3):274.
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    59. McCloskey MS, New AS, Siever LJ, Goodman M, Koenigsberg HW, Flory JD, Coccaro EF. Evaluation of behavioral impulsivity and aggression tasks as endophenotypes for borderline personality disorder. J Psychiatr Res. 2009 Aug; 43(12):1036-48.
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    60. New AS, Goodman M, Triebwasser J, Siever LJ. Recent advances in the biological study of personality disorders. Psychiatr Clin North Am. 2008 Sep; 31(3):441-61, vii.
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    61. Flory JD, Yehuda R, Grossman R, New AS, Mitropoulou V, Siever LJ. Childhood trauma and basal cortisol in people with personality disorders. Compr Psychiatry. 2009 Jan-Feb; 50(1):34-7.
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    62. Turetsky BI, Greenwood TA, Olincy A, Radant AD, Braff DL, Cadenhead KS, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Calkins ME. Abnormal auditory N100 amplitude: a heritable endophenotype in first-degree relatives of schizophrenia probands. Biol Psychiatry. 2008 Dec 15; 64(12):1051-9.
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    63. Hazlett EA, Buchsbaum MS, Zhang J, Newmark RE, Glanton CF, Zelmanova Y, Haznedar MM, Chu KW, Nenadic I, Kemether EM, Tang CY, New AS, Siever LJ. Frontal-striatal-thalamic mediodorsal nucleus dysfunction in schizophrenia-spectrum patients during sensorimotor gating. Neuroimage. 2008 Sep 1; 42(3):1164-77.
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    64. McClure MM, Barch DM, Flory JD, Harvey PD, Siever LJ. Context processing in schizotypal personality disorder: evidence of specificity of impairment to the schizophrenia spectrum. J Abnorm Psychol. 2008 May; 117(2):342-54.
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    65. Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA, Cook EH, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biol Psychiatry. 2008 Apr 15; 63(8):725-7.
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    66. Horan WP, Braff DL, Nuechterlein KH, Sugar CA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Olincy A, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Green MF. Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. Schizophr Res. 2008 Aug; 103(1-3):218-28.
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    67. Siever LJ. Neurobiology of aggression and violence. Am J Psychiatry. 2008 Apr; 165(4):429-42.
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    68. Henry C, Van den Bulke D, Bellivier F, Roy I, Swendsen J, M'Baïlara K, Siever LJ, Leboyer M. Affective lability and affect intensity as core dimensions of bipolar disorders during euthymic period. Psychiatry Res. 2008 May 30; 159(1-2):1-6.
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    69. Hazlett EA, Buchsbaum MS, Haznedar MM, Newmark R, Goldstein KE, Zelmanova Y, Glanton CF, Torosjan Y, New AS, Lo JN, Mitropoulou V, Siever LJ. Cortical gray and white matter volume in unmedicated schizotypal and schizophrenia patients. Schizophr Res. 2008 Apr; 101(1-3):111-23.
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    70. Flory JD, Xu K, New AS, Finch T, Goldman D, Siever LJ. Irritable assault and variation in the COMT gene. Psychiatr Genet. 2007 Dec; 17(6):344-6.
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    71. Leung WW, McClure MM, Siever LJ, Barch DM, Harvey PD. Catechol-O-methyltransferase Val158Met genotype in healthy and personality disorder individuals: Preliminary results from an examination of cognitive tests hypothetically differentially sensitive to dopamine functions. Neuropsychiatr Dis Treat. 2007 Dec; 3(6):925-34.
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    72. Greenwood TA, Braff DL, Light GA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Schork NJ. Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry. 2007 Nov; 64(11):1242-50.
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    73. Dracheva S, Patel N, Woo DA, Marcus SM, Siever LJ, Haroutunian V. Increased serotonin 2C receptor mRNA editing: a possible risk factor for suicide. Mol Psychiatry. 2008 Nov; 13(11):1001-10.
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    74. Minzenberg MJ, Fan J, New AS, Tang CY, Siever LJ. Frontolimbic structural changes in borderline personality disorder. J Psychiatr Res. 2008 Jul; 42(9):727-33.
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    75. Freedman R, Ross R, Michels R, Appelbaum P, Siever L, Binder R, Carpenter W, Friedman SH, Resnick P, Rosenbaum J. Psychiatrists, mental illness, and violence. Am J Psychiatry. 2007 Sep; 164(9):1315-7.
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    76. Minzenberg MJ, Fan J, New AS, Tang CY, Siever LJ. Fronto-limbic dysfunction in response to facial emotion in borderline personality disorder: an event-related fMRI study. Psychiatry Res. 2007 Aug 15; 155(3):231-43.
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    77. Hazlett EA, Romero MJ, Haznedar MM, New AS, Goldstein KE, Newmark RE, Siever LJ, Buchsbaum MS. Deficient attentional modulation of startle eyeblink is associated with symptom severity in the schizophrenia spectrum. Schizophr Res. 2007 Jul; 93(1-3):288-95.
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    78. Swerdlow NR, Sprock J, Light GA, Cadenhead K, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Mintz J, Olincy A, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophr Res. 2007 May; 92(1-3):237-51.
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    79. Hazlett EA, Speiser LJ, Goodman M, Roy M, Carrizal M, Wynn JK, Williams WC, Romero M, Minzenberg MJ, Siever LJ, New AS. Exaggerated affect-modulated startle during unpleasant stimuli in borderline personality disorder. Biol Psychiatry. 2007 Aug 1; 62(3):250-5.
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    80. New AS, Hazlett EA, Buchsbaum MS, Goodman M, Mitelman SA, Newmark R, Trisdorfer R, Haznedar MM, Koenigsberg HW, Flory J, Siever LJ. Amygdala-prefrontal disconnection in borderline personality disorder. Neuropsychopharmacology. 2007 Jul; 32(7):1629-40.
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    81. Herpertz SC, Zanarini M, Schulz CS, Siever L, Lieb K, Möller HJ. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of personality disorders. World J Biol Psychiatry. 2007; 8(4):212-44.
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    82. McClure MM, Romero MJ, Bowie CR, Reichenberg A, Harvey PD, Siever LJ. Visual-spatial learning and memory in schizotypal personality disorder: continued evidence for the importance of working memory in the schizophrenia spectrum. Arch Clin Neuropsychol. 2007 Jan; 22(1):109-16.
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    83. Calkins ME, Dobie DJ, Cadenhead KS, Olincy A, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophr Bull. 2007 Jan; 33(1):33-48.
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    84. Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Light GA, Meichle SP, Mintz J, Nuechterlein KH, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang MT, Turetsky BI, Tsuang DW. Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophr Res. 2007 Jan; 89(1-3):320-9.
      View in: PubMed
    85. McClure MM, Barch DM, Romero MJ, Minzenberg MJ, Triebwasser J, Harvey PD, Siever LJ. The effects of guanfacine on context processing abnormalities in schizotypal personality disorder. Biol Psychiatry. 2007 May 15; 61(10):1157-60.
      View in: PubMed
    86. Harvey PD, Reichenberg A, Romero M, Granholm E, Siever LJ. Dual-task information processing in schizotypal personality disorder: evidence of impaired processing capacity. Neuropsychology. 2006 Jul; 20(4):453-60.
      View in: PubMed
    87. Minzenberg MJ, Xu K, Mitropoulou V, Harvey PD, Finch T, Flory JD, New AS, Goldman D, Siever LJ. Catechol-O-methyltransferase Val158Met genotype variation is associated with prefrontal-dependent task performance in schizotypal personality disorder patients and comparison groups. Psychiatr Genet. 2006 Jun; 16(3):117-24.
      View in: PubMed
    88. Flory JD, Harvey PD, Mitropoulou V, New AS, Silverman JM, Siever LJ, Manuck SB. Dispositional impulsivity in normal and abnormal samples. J Psychiatr Res. 2006 Aug; 40(5):438-47.
      View in: PubMed
    89. Minzenberg MJ, Grossman R, New AS, Mitropoulou V, Yehuda R, Goodman M, Reynolds DA, Silverman JM, Coccaro EF, Marcus S, Siever LJ. Blunted hormone responses to Ipsapirone are associated with trait impulsivity in personality disorder patients. Neuropsychopharmacology. 2006 Jan; 31(1):197-203.
      View in: PubMed
    90. Mitropoulou V, Harvey PD, Zegarelli G, New AS, Silverman JM, Siever LJ. Neuropsychological performance in schizotypal personality disorder: importance of working memory. Am J Psychiatry. 2005 Oct; 162(10):1896-903.
      View in: PubMed
    91. Bespalova IN, Angelo GW, Durner M, Smith CJ, Siever LJ, Buxbaum JD, Silverman JM. Fine mapping of the 5p13 locus linked to schizophrenia and schizotypal personality disorder in a Puerto Rican family. Psychiatr Genet. 2005 Sep; 15(3):205-10.
      View in: PubMed
    92. Hazlett EA, New AS, Newmark R, Haznedar MM, Lo JN, Speiser LJ, Chen AD, Mitropoulou V, Minzenberg M, Siever LJ, Buchsbaum MS. Reduced anterior and posterior cingulate gray matter in borderline personality disorder. Biol Psychiatry. 2005 Oct 15; 58(8):614-23.
      View in: PubMed
    93. Koenigsberg HW, Buchsbaum MS, Buchsbaum BR, Schneiderman JS, Tang CY, New A, Goodman M, Siever LJ. Functional MRI of visuospatial working memory in schizotypal personality disorder: a region-of-interest analysis. Psychol Med. 2005 Jul; 35(7):1019-30.
      View in: PubMed
    94. Frankle WG, Lombardo I, New AS, Goodman M, Talbot PS, Huang Y, Hwang DR, Slifstein M, Curry S, Abi-Dargham A, Laruelle M, Siever LJ. Brain serotonin transporter distribution in subjects with impulsive aggressivity: a positron emission study with [11C]McN 5652. Am J Psychiatry. 2005 May; 162(5):915-23.
      View in: PubMed
    95. Leboyer M, Slama F, Siever L, Bellivier F. Suicidal disorders: a nosological entity per se? Am J Med Genet C Semin Med Genet. 2005 Feb 15; 133C(1):3-7.
      View in: PubMed
    96. Siever LJ. Endophenotypes in the personality disorders. Dialogues Clin Neurosci. 2005; 7(2):139-51.
      View in: PubMed
    97. Goodman M, New A, Siever L. Trauma, genes, and the neurobiology of personality disorders. Ann N Y Acad Sci. 2004 Dec; 1032:104-16.
      View in: PubMed
    98. Haznedar MM, Buchsbaum MS, Hazlett EA, Shihabuddin L, New A, Siever LJ. Cingulate gyrus volume and metabolism in the schizophrenia spectrum. Schizophr Res. 2004 Dec 1; 71(2-3):249-62.
      View in: PubMed
    99. Barch DM, Mitropoulou V, Harvey PD, New AS, Silverman JM, Siever LJ. Context-processing deficits in schizotypal personality disorder. J Abnorm Psychol. 2004 Nov; 113(4):556-68.
      View in: PubMed
    100. Grossman R, Reynolds D, Goodman M, New A, Silverman J, Schmeidler J, Mitropoulou V, Siever LJ. Efficacy of open-label venlafaxine in subjects with major depressive disorder: associations with neuroendocrine response to serotonergic and noradrenergic probes. Psychiatry Res. 2004 Sep 30; 128(2):203-6.
      View in: PubMed
    101. Mitropoulou V, Goodman M, Sevy S, Elman I, New AS, Iskander EG, Silverman JM, Breier A, Siever LJ. Effects of acute metabolic stress on the dopaminergic and pituitary-adrenal axis activity in patients with schizotypal personality disorder. Schizophr Res. 2004 Sep 1; 70(1):27-31.
      View in: PubMed
    102. Koenigsberg HW, Teicher MH, Mitropoulou V, Navalta C, New AS, Trestman R, Siever LJ. 24-h Monitoring of plasma norepinephrine, MHPG, cortisol, growth hormone and prolactin in depression. J Psychiatr Res. 2004 Sep-Oct; 38(5):503-11.
      View in: PubMed
    103. New AS, Buchsbaum MS, Hazlett EA, Goodman M, Koenigsberg HW, Lo J, Iskander L, Newmark R, Brand J, O'Flynn K, Siever LJ. Fluoxetine increases relative metabolic rate in prefrontal cortex in impulsive aggression. Psychopharmacology (Berl). 2004 Nov; 176(3-4):451-8.
      View in: PubMed
    104. Abi-Dargham A, Kegeles LS, Zea-Ponce Y, Mawlawi O, Martinez D, Mitropoulou V, O'Flynn K, Koenigsberg HW, Van Heertum R, Cooper T, Laruelle M, Siever LJ. Striatal amphetamine-induced dopamine release in patients with schizotypal personality disorder studied with single photon emission computed tomography and [123I]iodobenzamide. Biol Psychiatry. 2004 May 15; 55(10):1001-6.
      View in: PubMed
    105. New AS, Trestman RF, Mitropoulou V, Goodman M, Koenigsberg HH, Silverman J, Siever LJ. Low prolactin response to fenfluramine in impulsive aggression. J Psychiatr Res. 2004 May-Jun; 38(3):223-30.
      View in: PubMed
    106. Goldman-Rakic PS, Castner SA, Svensson TH, Siever LJ, Williams GV. Targeting the dopamine D1 receptor in schizophrenia: insights for cognitive dysfunction. Psychopharmacology (Berl). 2004 Jun; 174(1):3-16.
      View in: PubMed
    107. Siever LJ, Davis KL. The pathophysiology of schizophrenia disorders: perspectives from the spectrum. Am J Psychiatry. 2004 Mar; 161(3):398-413.
      View in: PubMed
    108. Dracheva S, Elhakem SL, Marcus SM, Siever LJ, McGurk SR, Haroutunian V. RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia. J Neurochem. 2003 Dec; 87(6):1402-12.
      View in: PubMed
    109. Golier JA, Yehuda R, Bierer LM, Mitropoulou V, New AS, Schmeidler J, Silverman JM, Siever LJ. The relationship of borderline personality disorder to posttraumatic stress disorder and traumatic events. Am J Psychiatry. 2003 Nov; 160(11):2018-24.
      View in: PubMed
    110. Siever LJ. Refining the approaches to personality disorders. CNS Spectr. 2003 Oct; 8(10):724.
      View in: PubMed
    111. Bierer LM, Yehuda R, Schmeidler J, Mitropoulou V, New AS, Silverman JM, Siever LJ. Abuse and neglect in childhood: relationship to personality disorder diagnoses. CNS Spectr. 2003 Oct; 8(10):737-54.
      View in: PubMed
    112. Goodman M, Weiss DS, Koenigsberg H, Kotlyarevsky V, New AS, Mitropoulou V, Silverman JM, O'Flynn K, Siever LJ. The role of childhood trauma in differences in affective instability in those with personality disorders. CNS Spectr. 2003 Oct; 8(10):763-70.
      View in: PubMed
    113. Mitropoulou V, Trestman RL, New AS, Flory JD, Silverman JM, Siever LJ. Neurobiologic function and temperament in subjects with personality disorders. CNS Spectr. 2003 Oct; 8(10):725-30.
      View in: PubMed
    114. Hazlett EA, Levine J, Buchsbaum MS, Silverman JM, New A, Sevin EM, Maldari LA, Siever LJ. Deficient attentional modulation of the startle response in patients with schizotypal personality disorder. Am J Psychiatry. 2003 Sep; 160(9):1621-6.
      View in: PubMed
    115. Grossman R, Yehuda R, New A, Schmeidler J, Silverman J, Mitropoulou V, Sta Maria N, Golier J, Siever L. Dexamethasone suppression test findings in subjects with personality disorders: associations with posttraumatic stress disorder and major depression. Am J Psychiatry. 2003 Jul; 160(7):1291-8.
      View in: PubMed
    116. Koenigsberg HW, Reynolds D, Goodman M, New AS, Mitropoulou V, Trestman RL, Silverman J, Siever LJ. Risperidone in the treatment of schizotypal personality disorder. J Clin Psychiatry. 2003 Jun; 64(6):628-34.
      View in: PubMed
    117. Moriarty PJ, Harvey PD, Mitropoulou V, Granholm E, Silverman JM, Siever LJ. Reduced processing resource availability in schizotypal personality disorder: evidence from a dual-task CPT study. J Clin Exp Neuropsychol. 2003 May; 25(3):335-47.
      View in: PubMed
    118. Halperin JM, Newcorn JH, McKay KE, Siever LJ, Sharma V. Growth hormone response to guanfacine in boys with attention deficit hyperactivity disorder: a preliminary study. J Child Adolesc Psychopharmacol. 2003; 13(3):283-94.
      View in: PubMed
    119. New AS, Siever LJ. Biochemical endophenotypes in personality disorders. Methods Mol Med. 2003; 77:199-213.
      View in: PubMed
    120. Mitropoulou V, Harvey PD, Maldari LA, Moriarty PJ, New AS, Silverman JM, Siever LJ. Neuropsychological performance in schizotypal personality disorder: evidence regarding diagnostic specificity. Biol Psychiatry. 2002 Dec 15; 52(12):1175-82.
      View in: PubMed
    121. Bernstein ME, Reich DB, Zanarini MC, Siever LJ. "Late-onset" borderline personality disorder: a life unraveling. Harv Rev Psychiatry. 2002 Sep-Oct; 10(5):292-301.
      View in: PubMed
    122. New AS, Hazlett EA, Buchsbaum MS, Goodman M, Reynolds D, Mitropoulou V, Sprung L, Shaw RB, Koenigsberg H, Platholi J, Silverman J, Siever LJ. Blunted prefrontal cortical 18fluorodeoxyglucose positron emission tomography response to meta-chlorophenylpiperazine in impulsive aggression. Arch Gen Psychiatry. 2002 Jul; 59(7):621-9.
      View in: PubMed
    123. Skodol AE, Gunderson JG, Pfohl B, Widiger TA, Livesley WJ, Siever LJ. The borderline diagnosis I: psychopathology, comorbidity, and personality structure. Biol Psychiatry. 2002 Jun 15; 51(12):936-50.
      View in: PubMed
    124. Skodol AE, Siever LJ, Livesley WJ, Gunderson JG, Pfohl B, Widiger TA. The borderline diagnosis II: biology, genetics, and clinical course. Biol Psychiatry. 2002 Jun 15; 51(12):951-63.
      View in: PubMed
    125. Siever LJ, Torgersen S, Gunderson JG, Livesley WJ, Kendler KS. The borderline diagnosis III: identifying endophenotypes for genetic studies. Biol Psychiatry. 2002 Jun 15; 51(12):964-8.
      View in: PubMed
    126. Koenigsberg HW, Harvey PD, Mitropoulou V, Schmeidler J, New AS, Goodman M, Silverman JM, Serby M, Schopick F, Siever LJ. Characterizing affective instability in borderline personality disorder. Am J Psychiatry. 2002 May; 159(5):784-8.
      View in: PubMed
    127. Buchsbaum MS, Nenadic I, Hazlett EA, Spiegel-Cohen J, Fleischman MB, Akhavan A, Silverman JM, Siever LJ. Differential metabolic rates in prefrontal and temporal Brodmann areas in schizophrenia and schizotypal personality disorder. Schizophr Res. 2002 Mar 1; 54(1-2):141-50.
      View in: PubMed
    128. Siever LJ, Koenigsberg HW, Harvey P, Mitropoulou V, Laruelle M, Abi-Dargham A, Goodman M, Buchsbaum M. Cognitive and brain function in schizotypal personality disorder. Schizophr Res. 2002 Mar 1; 54(1-2):157-67.
      View in: PubMed
    129. Henry C, Mitropoulou V, New AS, Koenigsberg HW, Silverman J, Siever LJ. Affective instability and impulsivity in borderline personality and bipolar II disorders: similarities and differences. J Psychiatr Res. 2001 Nov-Dec; 35(6):307-12.
      View in: PubMed
    130. Shihabuddin L, Buchsbaum MS, Hazlett EA, Silverman J, New A, Brickman AM, Mitropoulou V, Nunn M, Fleischman MB, Tang C, Siever LJ. Striatal size and relative glucose metabolic rate in schizotypal personality disorder and schizophrenia. Arch Gen Psychiatry. 2001 Sep; 58(9):877-84.
      View in: PubMed
    131. Koenigsberg HW, Harvey PD, Mitropoulou V, New AS, Goodman M, Silverman J, Serby M, Schopick F, Siever LJ. Are the interpersonal and identity disturbances in the borderline personality disorder criteria linked to the traits of affective instability and impulsivity? J Pers Disord. 2001 Aug; 15(4):358-70.
      View in: PubMed
    132. New AS, Gelernter J, Goodman M, Mitropoulou V, Koenigsberg H, Silverman J, Siever LJ. Suicide, impulsive aggression, and HTR1B genotype. Biol Psychiatry. 2001 Jul 1; 50(1):62-5.
      View in: PubMed
    133. Downhill JE, Buchsbaum MS, Hazlett EA, Barth S, Lees Roitman S, Nunn M, Lekarev O, Wei T, Shihabuddin L, Mitropoulou V, Silverman J, Siever LJ. Temporal lobe volume determined by magnetic resonance imaging in schizotypal personality disorder and schizophrenia. Schizophr Res. 2001 Mar 30; 48(2-3):187-99.
      View in: PubMed
    134. Kirrane RM, Mitropoulou V, Nunn M, Silverman J, Siever LJ. Physostigmine and cognition in schizotypal personality disorder. Schizophr Res. 2001 Mar 1; 48(1):1-5.
      View in: PubMed
    135. Hollander E, Allen A, Lopez RP, Bienstock CA, Grossman R, Siever LJ, Merkatz L, Stein DJ. A preliminary double-blind, placebo-controlled trial of divalproex sodium in borderline personality disorder. J Clin Psychiatry. 2001 Mar; 62(3):199-203.
      View in: PubMed
    136. Schulz KP, Newcorn JH, McKay KE, Himelstein J, Koda VH, Siever LJ, Sharma V, Halperin JM. Relationship between central serotonergic function and aggression in prepubertal boys: effect of age and attention-deficit/hyperactivity disorder. Psychiatry Res. 2001 Feb 14; 101(1):1-10.
      View in: PubMed
    137. Byne W, Buchsbaum MS, Kemether E, Hazlett EA, Shinwari A, Mitropoulou V, Siever LJ. Magnetic resonance imaging of the thalamic mediodorsal nucleus and pulvinar in schizophrenia and schizotypal personality disorder. Arch Gen Psychiatry. 2001 Feb; 58(2):133-40.
      View in: PubMed
    138. Golier JA, Yehuda R, Schmeidler J, Siever LJ. Variability and severity of depression and anxiety in post traumatic stress disorder and major depressive disorder. Depress Anxiety. 2001; 13(2):97-100.
      View in: PubMed
    139. Siever LJ. Antidepressant selection in the postgenomic era. Biol Psychiatry. 2000 Nov 1; 48(9):875-7.
      View in: PubMed
    140. Downhill JE, Buchsbaum MS, Wei T, Spiegel-Cohen J, Hazlett EA, Haznedar MM, Silverman J, Siever LJ. Shape and size of the corpus callosum in schizophrenia and schizotypal personality disorder. Schizophr Res. 2000 May 5; 42(3):193-208.
      View in: PubMed
    141. Nancarrow DJ, Levinson DF, Taylor JM, Hayward NK, Walters MK, Lennon DP, Nertney DA, Jones HL, Mahtani MM, Kirby A, Kruglyak L, Brown DM, Crowe RR, Andreasen NC, Black DW, Silverman JM, Mohs RC, Siever LJ, Endicott J, Sharpe L, Mowry BJ. No support for linkage to the bipolar regions on chromosomes 4p, 18p, or 18q in 43 schizophrenia pedigrees. Am J Med Genet. 2000 Apr 3; 96(2):224-7.
      View in: PubMed
    142. Gurvits IG, Koenigsberg HW, Siever LJ. Neurotransmitter dysfunction in patients with borderline personality disorder. Psychiatr Clin North Am. 2000 Mar; 23(1):27-40, vi.
      View in: PubMed
    143. Roitman SE, Mitropoulou V, Keefe RS, Silverman JM, Serby M, Harvey PD, Reynolds DA, Mohs RC, Siever LJ. Visuospatial working memory in schizotypal personality disorder patients. Schizophr Res. 2000 Feb 14; 41(3):447-55.
      View in: PubMed
    144. Kirrane RM, Siever LJ. New perspectives on schizotypal personality disorder. Curr Psychiatry Rep. 2000 Feb; 2(1):62-6.
      View in: PubMed
    145. Kirrane RM, Mitropoulou V, Nunn M, New AS, Harvey PD, Schopick F, Silverman J, Siever LJ. Effects of amphetamine on visuospatial working memory performance in schizophrenia spectrum personality disorder. Neuropsychopharmacology. 2000 Jan; 22(1):14-8.
      View in: PubMed
    146. Bergman AJ, Silverman JM, Harvey PD, Smith CJ, Siever LJ. Schizotypal symptoms in the relatives of schizophrenia patients: an empirical analysis of the factor structure. Schizophr Bull. 2000; 26(3):577-86.
      View in: PubMed
    147. New AS, Woo-Ming A, Mitropoulou V, Silverman J, Reynolds D, Schopick F, Trestman RL, Siever LJ. Serotonin and the prediction of response time to fluoxetine in patients with mild depression. Psychiatry Res. 1999 Nov 8; 88(2):89-93.
      View in: PubMed
    148. Hazlett EA, Buchsbaum MS, Byne W, Wei TC, Spiegel-Cohen J, Geneve C, Kinderlehrer R, Haznedar MM, Shihabuddin L, Siever LJ. Three-dimensional analysis with MRI and PET of the size, shape, and function of the thalamus in the schizophrenia spectrum. Am J Psychiatry. 1999 Aug; 156(8):1190-9.
      View in: PubMed
    149. Siever LJ, Buchsbaum MS, New AS, Spiegel-Cohen J, Wei T, Hazlett EA, Sevin E, Nunn M, Mitropoulou V. d,l-fenfluramine response in impulsive personality disorder assessed with [18F]fluorodeoxyglucose positron emission tomography. Neuropsychopharmacology. 1999 May; 20(5):413-23.
      View in: PubMed
    150. Amin F, Silverman JM, Siever LJ, Smith CJ, Knott PJ, Davis KL. Genetic antecedents of dopamine dysfunction in schizophrenia. Biol Psychiatry. 1999 May 1; 45(9):1143-50.
      View in: PubMed
    151. New AS, Sevin EM, Mitropoulou V, Reynolds D, Novotny SL, Callahan A, Trestman RL, Siever LJ. Serum cholesterol and impulsivity in personality disorders. Psychiatry Res. 1999 Feb 22; 85(2):145-50.
      View in: PubMed
    152. Koenigsberg HW, Anwunah I, New AS, Mitropoulou V, Schopick F, Siever LJ. Relationship between depression and borderline personality disorder. Depress Anxiety. 1999; 10(4):158-67.
      View in: PubMed
    153. Gelernter J, Kranzler H, Coccaro EF, Siever LJ, New AS. Serotonin transporter protein gene polymorphism and personality measures in African American and European American subjects. Am J Psychiatry. 1998 Oct; 155(10):1332-8.
      View in: PubMed
    154. Handelsman L, Kahn RS, Sturiano C, Rinaldi PJ, Gabriel S, Schmeidler JP, Bernstein DP, Siever L, Cooper TB. Hostility is associated with a heightened prolactin response to meta-chlorophenylpiperazine in abstinent cocaine addicts. Psychiatry Res. 1998 Jul 27; 80(1):1-12.
      View in: PubMed
    155. Yehuda R, Siever LJ, Teicher MH, Levengood RA, Gerber DK, Schmeidler J, Yang RK. Plasma norepinephrine and 3-methoxy-4-hydroxyphenylglycol concentrations and severity of depression in combat posttraumatic stress disorder and major depressive disorder. Biol Psychiatry. 1998 Jul 1; 44(1):56-63.
      View in: PubMed
    156. Levinson DF, Mahtani MM, Nancarrow DJ, Brown DM, Kruglyak L, Kirby A, Hayward NK, Crowe RR, Andreasen NC, Black DW, Silverman JM, Endicott J, Sharpe L, Mohs RC, Siever LJ, Walters MK, Lennon DP, Jones HL, Nertney DA, Daly MJ, Gladis M, Mowry BJ. Genome scan of schizophrenia. Am J Psychiatry. 1998 Jun; 155(6):741-50.
      View in: PubMed
    157. Yehuda R, Schmeidler J, Giller EL, Siever LJ, Binder-Brynes K. Relationship between posttraumatic stress disorder characteristics of Holocaust survivors and their adult offspring. Am J Psychiatry. 1998 Jun; 155(6):841-3.
      View in: PubMed
    158. New AS, Gelernter J, Yovell Y, Trestman RL, Nielsen DA, Silverman J, Mitropoulou V, Siever LJ. Tryptophan hydroxylase genotype is associated with impulsive-aggression measures: a preliminary study. Am J Med Genet. 1998 Feb 7; 81(1):13-7.
      View in: PubMed
    159. Silverman JM, Smith CJ, Guo SL, Mohs RC, Siever LJ, Davis KL. Lateral ventricular enlargement in schizophrenic probands and their siblings with schizophrenia-related disorders. Biol Psychiatry. 1998 Jan 15; 43(2):97-106.
      View in: PubMed
    160. Bergman AJ, Harvey PD, Roitman SL, Mohs RC, Marder D, Silverman JM, Siever LJ. Verbal learning and memory in schizotypal personality disorder. Schizophr Bull. 1998; 24(4):635-41.
      View in: PubMed
    161. Coccaro EF, Kavoussi RJ, Trestman RL, Gabriel SM, Cooper TB, Siever LJ. Serotonin function in human subjects: intercorrelations among central 5-HT indices and aggressiveness. Psychiatry Res. 1997 Nov 14; 73(1-2):1-14.
      View in: PubMed
    162. Gelernter J, Kranzler H, Coccaro E, Siever L, New A, Mulgrew CL. D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects. Am J Hum Genet. 1997 Nov; 61(5):1144-52.
      View in: PubMed
    163. Buchsbaum MS, Yang S, Hazlett E, Siegel BV, Germans M, Haznedar M, O'Flaithbheartaigh S, Wei T, Silverman J, Siever LJ. Ventricular volume and asymmetry in schizotypal personality disorder and schizophrenia assessed with magnetic resonance imaging. Schizophr Res. 1997 Oct 17; 27(1):45-53.
      View in: PubMed
    164. Buchsbaum MS, Trestman RL, Hazlett E, Siegel BV, Schaefer CH, Luu-Hsia C, Tang C, Herrera S, Solimando AC, Losonczy M, Serby M, Silverman J, Siever LJ. Regional cerebral blood flow during the Wisconsin Card Sort Test in schizotypal personality disorder. Schizophr Res. 1997 Oct 17; 27(1):21-8.
      View in: PubMed
    165. Steinberg BJ, Trestman R, Mitropoulou V, Serby M, Silverman J, Coccaro E, Weston S, de Vegvar M, Siever LJ. Depressive response to physostigmine challenge in borderline personality disorder patients. Neuropsychopharmacology. 1997 Oct; 17(4):264-73.
      View in: PubMed
    166. Halperin JM, Newcorn JH, Kopstein I, McKay KE, Schwartz ST, Siever LJ, Sharma V. Serotonin, aggression, and parental psychopathology in children with attention-deficit hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 1997 Oct; 36(10):1391-8.
      View in: PubMed
    167. Roitman SE, Keefe RS, Harvey PD, Siever LJ, Mohs RC. Attentional and eye tracking deficits correlate with negative symptoms in schizophrenia. Schizophr Res. 1997 Aug 29; 26(2-3):139-46.
      View in: PubMed
    168. Yehuda R, Schmeidler J, Siever LJ, Binder-Brynes K, Elkin A. Individual differences in posttraumatic stress disorder symptom profiles in Holocaust survivors in concentration camps or in hiding. J Trauma Stress. 1997 Jul; 10(3):453-63.
      View in: PubMed
    169. Grossman R, Yehuda R, Siever L. The dexamethasone suppression test and glucocorticoid receptors in borderline personality disorder. Ann N Y Acad Sci. 1997 Jun 21; 821:459-64.
      View in: PubMed
    170. Roitman SE, Cornblatt BA, Bergman A, Obuchowski M, Mitropoulou V, Keefe RS, Silverman JM, Siever LJ. Attentional functioning in schizotypal personality disorder. Am J Psychiatry. 1997 May; 154(5):655-60.
      View in: PubMed
    171. Li G, Silverman JM, Smith CJ, Zaccario ML, Wentzel-Bell C, Siever LJ, Mohs RC, Davis KL. Validity of the family history method for identifying schizophrenia-related disorders. Psychiatry Res. 1997 Apr 18; 70(1):39-48.
      View in: PubMed
    172. Halperin JM, Newcorn JH, Schwartz ST, Sharma V, Siever LJ, Koda VH, Gabriel S. Age-related changes in the association between serotonergic function and aggression in boys with ADHD. Biol Psychiatry. 1997 Mar 15; 41(6):682-9.
      View in: PubMed
    173. New AS, Trestman RL, Mitropoulou V, Benishay DS, Coccaro E, Silverman J, Siever LJ. Serotonergic function and self-injurious behavior in personality disorder patients. Psychiatry Res. 1997 Mar 3; 69(1):17-26.
      View in: PubMed
    174. Keefe RS, Silverman JM, Mohs RC, Siever LJ, Harvey PD, Friedman L, Roitman SE, DuPre RL, Smith CJ, Schmeidler J, Davis KL. Eye tracking, attention, and schizotypal symptoms in nonpsychotic relatives of patients with schizophrenia. Arch Gen Psychiatry. 1997 Feb; 54(2):169-76.
      View in: PubMed
    175. Bernstein DP, Kasapis C, Bergman A, Weld E, Mitropoulou V, Horvath T, Klar HM, Silverman J, Siever LJ. Assessing axis II disorders by informant interview. J Pers Disord. 1997; 11(2):158-67.
      View in: PubMed
    176. Handelsman L, Holloway K, Kahn RS, Sturiano C, Rinaldi PJ, Bernstein DP, Siever L, Gabriel S, Cooper TB. Hostility is associated with a low prolactin response to meta-chlorophenylpiperazine in abstinent alcoholics. Alcohol Clin Exp Res. 1996 Aug; 20(5):824-9.
      View in: PubMed
    177. Yehuda R, Teicher MH, Trestman RL, Levengood RA, Siever LJ. Cortisol regulation in posttraumatic stress disorder and major depression: a chronobiological analysis. Biol Psychiatry. 1996 Jul 15; 40(2):79-88.
      View in: PubMed
    178. Coccaro EF, Kavoussi RJ, Trestman RL, Gabriel SM, Cooper TB, Siever LJ. Hormonal responses to meta-chlorophenylpiperazine (m-CPP) are undiminished by acute m-CPP pretreatment. Psychiatry Res. 1996 May 17; 62(2):139-45.
      View in: PubMed
    179. Siegel BV, Trestman RL, O'Flaithbheartaigh S, Mitropoulou V, Amin F, Kirrane R, Silverman J, Schmeidler J, Keefe RS, Siever LJ. D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder. Schizophr Res. 1996 May; 20(1-2):29-32.
      View in: PubMed
    180. Milrod B, Busch FN, Hollander E, Aronson A, Siever L. A 23-year-old woman with panic disorder treated with psychodynamic psychotherapy. Am J Psychiatry. 1996 May; 153(5):698-703.
      View in: PubMed
    181. Silverman JM, Greenberg DA, Altstiel LD, Siever LJ, Mohs RC, Smith CJ, Zhou G, Hollander TE, Yang XP, Kedache M, Li G, Zaccario ML, Davis KL. Evidence of a locus for schizophrenia and related disorders on the short arm of chromosome 5 in a large pedigree. Am J Med Genet. 1996 Apr 9; 67(2):162-71.
      View in: PubMed
    182. Trestman RL, Horvath T, Kalus O, Peterson AE, Coccaro E, Mitropoulou V, Apter S, Davidson M, Siever LJ. Event-related potentials in schizotypal personality disorder. J Neuropsychiatry Clin Neurosci. 1996; 8(1):33-40.
      View in: PubMed
    183. Bergman AJ, Harvey PD, Mitropoulou V, Aronson A, Marder D, Silverman J, Trestman R, Siever LJ. The factor structure of schizotypal symptoms in a clinical population. Schizophr Bull. 1996; 22(3):501-9.
      View in: PubMed
    184. Stein DJ, Trestman RL, Mitropoulou V, Coccaro EF, Hollander E, Siever LJ. Impulsivity and serotonergic function in compulsive personality disorder. J Neuropsychiatry Clin Neurosci. 1996; 8(4):393-8.
      View in: PubMed
    185. Trestman RL, Keefe RS, Mitropoulou V, Harvey PD, deVegvar ML, Lees-Roitman S, Davidson M, Aronson A, Silverman J, Siever LJ. Cognitive function and biological correlates of cognitive performance in schizotypal personality disorder. Psychiatry Res. 1995 Nov 29; 59(1-2):127-36.
      View in: PubMed
    186. Mowry BJ, Nancarrow DJ, Lennon DP, Sandkuijl LA, Crowe RR, Silverman JM, Mohs RC, Siever LJ, Endicott J, Sharpe L, et al. Schizophrenia susceptibility and chromosome 6p24-22. Nat Genet. 1995 Nov; 11(3):233-4.
      View in: PubMed
    187. Siever LJ, Rotter M, Losonczy M, Guo SL, Mitropoulou V, Trestman R, Apter S, Zemishlany Z, Silverman J, Horvath TB. Lateral ventricular enlargement in schizotypal personality disorder. Psychiatry Res. 1995 Jul 28; 57(2):109-18.
      View in: PubMed
    188. Trestman RL, Yehuda R, Coccaro E, Horvath T, Knott P, Gabriel S, Siever LJ. Diurnal neuroendocrine and autonomic function in acute and remitted depressed male patients. Biol Psychiatry. 1995 Apr 1; 37(7):448-56.
      View in: PubMed
    189. Friedman L, Jesberger JA, Siever LJ, Thompson P, Mohs R, Meltzer HY. Smooth pursuit performance in patients with affective disorders or schizophrenia and normal controls: analysis with specific oculomotor measures, RMS error and qualitative ratings. Psychol Med. 1995 Mar; 25(2):387-403.
      View in: PubMed
    190. Yehuda R, Keefe RS, Harvey PD, Levengood RA, Gerber DK, Geni J, Siever LJ. Learning and memory in combat veterans with posttraumatic stress disorder. Am J Psychiatry. 1995 Jan; 152(1):137-9.
      View in: PubMed
    191. Yehuda R, Teicher MH, Levengood RA, Trestman RL, Siever LJ. Circadian regulation of basal cortisol levels in posttraumatic stress disorder. Ann N Y Acad Sci. 1994 Nov 30; 746:378-80.
      View in: PubMed
    192. Coccaro EF, Klar H, Siever LJ. Reduced prolactin response to fenfluramine challenge in personality disorder patients is not due to deficiency of pituitary lactotrophs. Biol Psychiatry. 1994 Sep 1; 36(5):344-6.
      View in: PubMed
    193. Siever LJ, Friedman L, Moskowitz J, Mitropoulou V, Keefe R, Roitman SL, Merhige D, Trestman R, Silverman J, Mohs R. Eye movement impairment and schizotypal psychopathology. Am J Psychiatry. 1994 Aug; 151(8):1209-15.
      View in: PubMed
    194. Keefe RS, Silverman JM, Roitman SE, Harvey PD, Duncan MA, Alroy D, Siever LJ, Davis KL, Mohs RC. Performance of nonpsychotic relatives of schizophrenic patients on cognitive tests. Psychiatry Res. 1994 Jul; 53(1):1-12.
      View in: PubMed
    195. Kahn RS, Davidson M, Siever LJ, Sevy S, Davis KL. Clozapine treatment and its effect on neuroendocrine responses induced by the serotonin agonist, m-chlorophenylpiperazine. Biol Psychiatry. 1994 Jun 15; 35(12):909-12.
      View in: PubMed
    196. Coccaro EF, Silverman JM, Klar HM, Horvath TB, Siever LJ. Familial correlates of reduced central serotonergic system function in patients with personality disorders. Arch Gen Psychiatry. 1994 Apr; 51(4):318-24.
      View in: PubMed
    197. Halperin JM, Sharma V, Siever LJ, Schwartz ST, Matier K, Wornell G, Newcorn JH. Serotonergic function in aggressive and nonaggressive boys with attention deficit hyperactivity disorder. Am J Psychiatry. 1994 Feb; 151(2):243-8.
      View in: PubMed
    198. Kahn RS, Trestman R, Lawlor BA, Gabriel S, Davidson M, Siever L. Effects of ipsapirone in healthy subjects: a dose-response study. Psychopharmacology (Berl). 1994 Feb; 114(1):155-60.
      View in: PubMed
    199. Siever LJ. Biologic factors in schizotypal personal disorders. Acta Psychiatr Scand Suppl. 1994; 384:45-50.
      View in: PubMed
    200. Trestman RL, Coccaro EF, Lawrence T, Knott P, Gabriel SM, Siever LJ. The stability of plasma growth hormone and MHPG responses to repeated clonidine challenge in normal males. Psychoneuroendocrinology. 1994; 19(1):13-20.
      View in: PubMed
    201. Siever L, Trestman RL. The serotonin system and aggressive personality disorder. Int Clin Psychopharmacol. 1993 Nov; 8 Suppl 2:33-9.
      View in: PubMed
    202. Trestman RL, Coccaro EF, Mitropoulou V, Gabriel SM, Horvath T, Siever LJ. The cortisol response to clonidine in acute and remitted depressed men. Biol Psychiatry. 1993 Sep 15; 34(6):373-9.
      View in: PubMed
    203. Kahn RS, Davidson M, Siever L, Gabriel S, Apter S, Davis KL. Serotonin function and treatment response to clozapine in schizophrenic patients. Am J Psychiatry. 1993 Sep; 150(9):1337-42.
      View in: PubMed
    204. Kavoussi RJ, Coccaro EF, Klar H, Lesser J, Siever LJ. The TRH-stimulation test in DSM-III personality disorder. Biol Psychiatry. 1993 Aug 15; 34(4):234-9.
      View in: PubMed
    205. Bernstein DP, Cohen P, Velez CN, Schwab-Stone M, Siever LJ, Shinsato L. Prevalence and stability of the DSM-III-R personality disorders in a community-based survey of adolescents. Am J Psychiatry. 1993 Aug; 150(8):1237-43.
      View in: PubMed
    206. Trestman RL, Coccaro EF, Apovian M, Bernstein D, Lawrence T, Knott P, Horvath TB, Siever LJ. Norepinephrine responses to postural and isometric stressors in acute and remitted depression. Psychiatry Res. 1993 Jun; 47(3):291-3.
      View in: PubMed
    207. Siever LJ, Kalus OF, Keefe RS. The boundaries of schizophrenia. Psychiatr Clin North Am. 1993 Jun; 16(2):217-44.
      View in: PubMed
    208. Silverman JM, Siever LJ, Horvath TB, Coccaro EF, Klar H, Davidson M, Pinkham L, Apter SH, Mohs RC, Davis KL. Schizophrenia-related and affective personality disorder traits in relatives of probands with schizophrenia and personality disorders. Am J Psychiatry. 1993 Mar; 150(3):435-42.
      View in: PubMed
    209. Siever LJ, Amin F, Coccaro EF, Trestman R, Silverman J, Horvath TB, Mahon TR, Knott P, Altstiel L, Davidson M, et al. CSF homovanillic acid in schizotypal personality disorder. Am J Psychiatry. 1993 Jan; 150(1):149-51.
      View in: PubMed
    210. Kahn RS, Siever L, Davidson M, Greenwald C, Moore C. Haloperidol and clozapine treatment and their effect on M-chlorophenylpiperazine-mediated responses in schizophrenia: implications for the mechanism of action of clozapine. Psychopharmacology (Berl). 1993; 112(1 Suppl):S90-4.
      View in: PubMed
    211. Kahn RS, Siever LJ, Gabriel S, Amin F, Stern RG, DuMont K, Apter S, Davidson M. Serotonin function in schizophrenia: effects of meta-chlorophenylpiperazine in schizophrenic patients and healthy subjects. Psychiatry Res. 1992 Jul; 43(1):1-12.
      View in: PubMed
    212. Siever LJ, Trestman RL, Coccaro EF, Bernstein D, Gabriel SM, Owen K, Moran M, Lawrence T, Rosenthal J, Horvath TB. The growth hormone response to clonidine in acute and remitted depressed male patients. Neuropsychopharmacology. 1992 May; 6(3):165-77.
      View in: PubMed
    213. Siever LJ, Trestman RL, Coccaro E, Amin F, Lawrence T, Gabriel S, Mitropoulou V. Monoamines in personality disorder. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:231A-232A.
      View in: PubMed
    214. Siever LJ, Coccaro EF, Trestman RL, Gabriel S. Use of serotonin-active agents in other psychiatric disorders. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:355A-356A.
      View in: PubMed
    215. Kavoussi RJ, Siever LJ. Overlap between borderline and schizotypal personality disorders. Compr Psychiatry. 1992 Jan-Feb; 33(1):7-12.
      View in: PubMed
    216. Siever LJ, Kahn RS, Lawlor BA, Trestman RL, Lawrence TL, Coccaro EF. Critical issues in defining the role of serotonin in psychiatric disorders. Pharmacol Rev. 1991 Dec; 43(4):509-25.
      View in: PubMed
    217. Siever LJ, Davis KL. A psychobiological perspective on the personality disorders. Am J Psychiatry. 1991 Dec; 148(12):1647-58.
      View in: PubMed
    218. Coccaro EF, Lawrence T, Trestman R, Gabriel S, Klar HM, Siever LJ. Growth hormone responses to intravenous clonidine challenge correlate with behavioral irritability in psychiatric patients and healthy volunteers. Psychiatry Res. 1991 Nov; 39(2):129-39.
      View in: PubMed
    219. Keefe RS, Silverman JM, Siever LJ, Cornblatt BA. Refining phenotype characterization in genetic linkage studies of schizophrenia. Soc Biol. 1991 Fall-Winter; 38(3-4):197-218.
      View in: PubMed
    220. Silverman JM, Pinkham L, Horvath TB, Coccaro EF, Klar H, Schear S, Apter S, Davidson M, Mohs RC, Siever LJ. Affective and impulsive personality disorder traits in the relatives of patients with borderline personality disorder. Am J Psychiatry. 1991 Oct; 148(10):1378-85.
      View in: PubMed
    221. Siever LJ, Amin F, Coccaro EF, Bernstein D, Kavoussi RJ, Kalus O, Horvath TB, Warne P, Davidson M, Davis KL. Plasma homovanillic acid in schizotypal personality disorder. Am J Psychiatry. 1991 Sep; 148(9):1246-8.
      View in: PubMed
    222. Trestman RL, Coccaro EF, Bernstein D, Lawrence T, Gabriel SM, Horvath TB, Siever LJ. Cortisol responses to mental arithmetic in acute and remitted depression. Biol Psychiatry. 1991 May 15; 29(10):1051-4.
      View in: PubMed
    223. Kavoussi RJ, Coccaro EF, Klar HM, Bernstein D, Siever LJ. Structured interviews for borderline personality disorder. Am J Psychiatry. 1990 Nov; 147(11):1522-5.
      View in: PubMed
    224. Siever LJ, Silverman JM, Horvath TB, Klar H, Coccaro E, Keefe RS, Pinkham L, Rinaldi P, Mohs RC, Davis KL. Increased morbid risk for schizophrenia-related disorders in relatives of schizotypal personality disordered patients. Arch Gen Psychiatry. 1990 Jul; 47(7):634-40.
      View in: PubMed
    225. Siever LJ, Keefe R, Bernstein DP, Coccaro EF, Klar HM, Zemishlany Z, Peterson AE, Davidson M, Mahon T, Horvath T, et al. Eye tracking impairment in clinically identified patients with schizotypal personality disorder. Am J Psychiatry. 1990 Jun; 147(6):740-5.
      View in: PubMed
    226. Coccaro EF, Gabriel S, Mahon T, Macaluso J, Siever LJ. Preliminary evidence of a serotonin (5-HT-1-like) component to the prolactin response to buspirone challenge in humans. Arch Gen Psychiatry. 1990 Jun; 47(6):594-5.
      View in: PubMed
    227. Coccaro EF, Gabriel S, Siever LJ. Buspirone challenge: preliminary evidence for a role for central 5-HT1a receptor function in impulsive aggressive behavior in humans. Psychopharmacol Bull. 1990; 26(3):393-405.
      View in: PubMed
    228. Coccaro EF, Siever LJ, Klar HM, Maurer G, Cochrane K, Cooper TB, Mohs RC, Davis KL. Serotonergic studies in patients with affective and personality disorders. Correlates with suicidal and impulsive aggressive behavior. Arch Gen Psychiatry. 1989 Jul; 46(7):587-99.
      View in: PubMed
    229. Siever LJ, Coursey RD, Alterman IS, Zahn T, Brody L, Bernad P, Buchsbaum M, Lake CR, Murphy DL. Clinical, psychophysiological, and neurological characteristics of volunteers with impaired smooth pursuit eye movements. Biol Psychiatry. 1989 May; 26(1):35-51.
      View in: PubMed
    230. Coursey RD, Lees RW, Siever LJ. The relationship between smooth pursuit eye movement impairment and psychological measures of psychopathology. Psychol Med. 1989 May; 19(2):343-58.
      View in: PubMed
    231. Kanof PD, Coccaro EF, Johns CA, Davidson M, Siever LJ, Davis KL. Cyclic-AMP production by polymorphonuclear leukocytes in psychiatric disorders. Biol Psychiatry. 1989 Feb 15; 25(4):413-20.
      View in: PubMed
    232. Uhde TW, Stein MB, Vittone BJ, Siever LJ, Boulenger JP, Klein E, Mellman TA. Behavioral and physiologic effects of short-term and long-term administration of clonidine in panic disorder. Arch Gen Psychiatry. 1989 Feb; 46(2):170-7.
      View in: PubMed
    233. Keefe RS, Siever LJ, Mohs RC, Peterson AE, Mahon TR, Bergman RL, Davis KL. Eye tracking, schizophrenic symptoms, and schizotypal personality disorder. Eur Arch Psychiatry Neurol Sci. 1989; 239(1):39-42.
      View in: PubMed
    234. Davis KL, Davidson M, Yang RK, Davis BM, Siever LJ, Mohs RC, Ryan T, Coccaro E, Bierer L, Targum SD. CSF somatostatin in Alzheimer's disease, depressed patients, and control subjects. Biol Psychiatry. 1988 Oct; 24(6):710-2.
      View in: PubMed
    235. Coccaro EF, Siever LJ, Kourides IA, Adan F, Campbell G, Davis KL. Central serotoninergic stimulation by fenfluramine challenge does not affect plasma thyrotropin-stimulating hormone levels in man. Neuroendocrinology. 1988 Apr; 47(4):273-6.
      View in: PubMed
    236. Sorokin JE, Giordani B, Mohs RC, Losonczy MF, Davidson M, Siever LJ, Ryan TA, Davis KL. Memory impairment in schizophrenic patients with tardive dyskinesia. Biol Psychiatry. 1988 Jan 15; 23(2):129-35.
      View in: PubMed
    237. Andreasen NC, Shore D, Burke JD, Grove WM, Lieberman JA, Oltmanns TF, Pettegrew JW, Pulver AE, Siever LJ, Tsuang MT, et al. Clinical phenomenology. Schizophr Bull. 1988; 14(3):345-63.
      View in: PubMed
    238. Kanof PD, Johns CA, Davidson M, Siever LJ, Coccaro EF, Davis KL. Platelet alpha 2-adrenergic receptor function in psychiatric disorders. Psychiatry Res. 1988 Jan; 23(1):11-22.
      View in: PubMed
    239. Hauger RL, Scheinin M, Siever LJ, Linnoila M, Potter WZ. Dissociation of norepinephrine turnover from alpha-2 responses after clorgiline. Clin Pharmacol Ther. 1988 Jan; 43(1):32-8.
      View in: PubMed
    240. Zemishlany Z, Siever LJ, Coccaro EF. Biologic factors in personality disorders. Isr J Psychiatry Relat Sci. 1988; 25(1):12-23.
      View in: PubMed
    241. Coccaro EF, Siever LJ, Klar H, Rubenstein K, Benjamin E, Davis KL. Diminished prolactin responses to repeated fenfluramine challenge in man. Psychiatry Res. 1987 Nov; 22(3):257-9.
      View in: PubMed
    242. Davidson M, Keefe RS, Mohs RC, Siever LJ, Losonczy MF, Horvath TB, Davis KL. L-dopa challenge and relapse in schizophrenia. Am J Psychiatry. 1987 Jul; 144(7):934-8.
      View in: PubMed
    243. Kanof PD, Coccaro EF, Johns CA, Siever LJ, Davis KL. Platelet [3H]imipramine binding in psychiatric disorders. Biol Psychiatry. 1987 Mar; 22(3):278-86.
      View in: PubMed
    244. Siever LJ, Tamminga C, Pert A. Increased growth hormone response to clonidine in 6-hydroxydopamine-treated rats. Psychopharmacology (Berl). 1987; 91(3):342-4.
      View in: PubMed
    245. Siever LJ, Insel TR, Hamilton J, Nurnberger J, Alterman I, Murphy DL. Eye-tracking, attention and amphetamine challenge. J Psychiatr Res. 1987; 21(2):129-35.
      View in: PubMed
    246. Siever LJ, Coccaro EF, Zemishlany Z, Silverman J, Klar H, Losonczy MF, Davidson M, Friedman R, Mohs RC, Davis KL. Psychobiology of personality disorders: pharmacologic implications. Psychopharmacol Bull. 1987; 23(3):333-6.
      View in: PubMed
    247. Siever LJ, van Kammen DP, Linnoila M, Alterman I, Hare T, Murphy DL. Smooth pursuit eye movement disorder and its psychobiologic correlates in unmedicated schizophrenics. Biol Psychiatry. 1986 Oct; 21(12):1167-74.
      View in: PubMed
    248. Kanof PD, Johns C, Davidson M, Siever LJ, Coccaro EF, Davis KL. Prostaglandin receptor sensitivity in psychiatric disorders. Arch Gen Psychiatry. 1986 Oct; 43(10):987-93.
      View in: PubMed
    249. Uhde TW, Vittone BJ, Siever LJ, Kaye WH, Post RM. Blunted growth hormone response to clonidine in panic disorder patients. Biol Psychiatry. 1986 Sep; 21(11):1081-5.
      View in: PubMed
    250. Siever LJ, Uhde TW, Jimerson DC, Lake CR, Kopin IJ, Murphy DL. Indices of noradrenergic output in depression. Psychiatry Res. 1986 Sep; 19(1):59-73.
      View in: PubMed
    251. Lewy AJ, Siever LJ, Uhde TW, Markey SP. Clonidine reduces plasma melatonin levels. J Pharm Pharmacol. 1986 Jul; 38(7):555-6.
      View in: PubMed
    252. Kafka MS, Nurnberger JI, Siever L, Targum S, Uhde TW, Gershon ES. Alpha 2-adrenergic receptor function in patients with unipolar and bipolar affective disorders. J Affect Disord. 1986 Mar-Apr; 10(2):163-9.
      View in: PubMed
    253. Siever LJ, Coccaro EF, Benjamin E, Rubinstein K, Davis KL. Adrenergic and serotonergic receptor responsiveness in depression. Ciba Found Symp. 1986; 123:148-63.
      View in: PubMed
    254. Siever LJ, Insel TR, Hamilton JA, Aloi J, Murphy DL. A comparison between the growth hormone responses to amphetamine and clonidine. Psychiatry Res. 1985 Sep; 16(1):79-82.
      View in: PubMed
    255. Siever LJ, Davis KL. Overview: toward a dysregulation hypothesis of depression. Am J Psychiatry. 1985 Sep; 142(9):1017-31.
      View in: PubMed
    256. Coccaro EF, Siever LJ. Second generation antidepressants: a comparative review. J Clin Pharmacol. 1985 May-Jun; 25(4):241-60.
      View in: PubMed
    257. Buchsbaum MS, Haier RJ, Sostek AJ, Weingartner H, Zahn TP, Siever LJ, Murphy DL. Attention dysfunction and psychopathology in college men. Arch Gen Psychiatry. 1985 Apr; 42(4):354-60.
      View in: PubMed
    258. Siever LJ. Biological markers in schizotypal personality disorder. Schizophr Bull. 1985; 11(4):564-75.
      View in: PubMed
    259. Insel TR, Mueller EA, Gillin JC, Siever LJ, Murphy DL. Tricyclic response in obsessive compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 1985; 9(1):25-31.
      View in: PubMed
    260. Siever LJ, Uhde TW, Insel TR, Kaye WH, Jimerson DC, Lake CR, Kafka M, Targum S, Murphy DL. Biological alterations in the primary affective disorders and other tricyclic-responsive disorders. Prog Neuropsychopharmacol Biol Psychiatry. 1985; 9(1):15-24.
      View in: PubMed
    261. Kafka MS, Siever LJ, Nurnberger JI, Uhde TW, Targum S, Cooper DM, van Kammen DP, Tokola NS. Platelet alpha-adrenergic receptor function in affective disorders and schizophrenia. Psychopharmacol Bull. 1985; 21(3):599-602.
      View in: PubMed
    262. Kaye WH, Gwirtsman HE, Lake CR, Siever LJ, Jimerson DC, Ebert MH, Murphy DL. Disturbances of norepinephrine metabolism and alpha-2 adrenergic receptor activity in anorexia nervosa: relationship to nutritional state. Psychopharmacol Bull. 1985; 21(3):419-23.
      View in: PubMed
    263. Siever LJ, Coursey RD. Biological markers for schizophrenia and the biological high-risk approach. J Nerv Ment Dis. 1985 Jan; 173(1):4-16.
      View in: PubMed
    264. Ross RJ, Scheinin M, Lesieur P, Rudorfer MV, Hauger RL, Siever LJ, Linnoila M, Potter WZ. The effect of clorgyline on noradrenergic function. Psychopharmacology (Berl). 1985; 85(2):227-30.
      View in: PubMed
    265. Gunderson JG, Siever LJ. Relatedness of schizotypal to schizophrenic disorders: editors' introduction. Schizophr Bull. 1985; 11(4):532-7.
      View in: PubMed
    266. Murphy DL, Siever LJ, Insel TR. Therapeutic responses to tricyclic antidepressants and related drugs in non-affective disorder patient populations. Prog Neuropsychopharmacol Biol Psychiatry. 1985; 9(1):3-13.
      View in: PubMed
    267. Siever LJ, Coursey RD, Alterman IS, Buchsbaum MS, Murphy DL. Impaired smooth pursuit eye movement: vulnerability marker for schizotypal personality disorder in a normal volunteer population. Am J Psychiatry. 1984 Dec; 141(12):1560-6.
      View in: PubMed
    268. Klar H, Siever LJ. The psychopharmacologic treatment of personality disorders. Psychiatr Clin North Am. 1984 Dec; 7(4):791-801.
      View in: PubMed
    269. Mirsky AF, DeLisi LE, Buchsbaum MS, Quinn OW, Schwerdt P, Siever LJ, Mann L, Weingartner H, Zec R, Sostek A, et al. The Genain Quadruplets: psychological studies. Psychiatry Res. 1984 Sep; 13(1):77-93.
      View in: PubMed
    270. Siever LJ, Uhde TW, Jimerson DC, Lake CR, Silberman ER, Post RM, Murphy DL. Differential inhibitory noradrenergic responses to clonidine in 25 depressed patients and 25 normal control subjects. Am J Psychiatry. 1984 Jun; 141(6):733-41.
      View in: PubMed
    271. Siever LJ, Kafka MS, Targum S, Lake CR. Platelet alpha-adrenergic binding and biochemical responsiveness in depressed patients and controls. Psychiatry Res. 1984 Apr; 11(4):287-302.
      View in: PubMed
    272. Siever LJ, Murphy DL, Slater S, de la Vega E, Lipper S. Plasma prolactin changes following fenfluramine in depressed patients compared to controls: an evaluation of central serotonergic responsivity in depression. Life Sci. 1984 Mar 12; 34(11):1029-39.
      View in: PubMed
    273. Siever LJ, Uhde TW. New studies and perspectives on the noradrenergic receptor system in depression: effects of the alpha 2-adrenergic agonist clonidine. Biol Psychiatry. 1984 Feb; 19(2):131-56.
      View in: PubMed
    274. Insel TR, Mueller EA, Gillin JC, Siever LJ, Murphy DL. Biological markers in obsessive-compulsive and affective disorders. J Psychiatr Res. 1984; 18(4):407-23.
      View in: PubMed
    275. Siever LJ, Davis KL. Dysregulation of the noradrenergic system in depression. Psychopharmacol Bull. 1984; 20(3):500-4.
      View in: PubMed
    276. Uhde TW, Boulenger JP, Post RM, Siever LJ, Vittone BJ, Jimerson DC, Roy-Byrne PP. Fear and anxiety: relationship to noradrenergic function. Psychopathology. 1984; 17 Suppl 3:8-23.
      View in: PubMed
    277. Siever LJ, Uhde TW, Jimerson DC, Post RM, Lake CR, Murphy DL. Plasma cortisol responses to clonidine in depressed patients and controls. Evidence for a possible alteration in noradrenergic-neuroendocrine relationships. Arch Gen Psychiatry. 1984 Jan; 41(1):63-8.
      View in: PubMed
    278. Siever LJ, Kafka MS, Insel TR, Lake CR, Murphy DL. Effect of long-term clorgyline administration on human platelet alpha-adrenergic receptor binding and platelet cyclic AMP responses. Psychiatry Res. 1983 May; 9(1):37-44.
      View in: PubMed
    279. Siever LJ, Gunderson JG. The search for a schizotypal personality: historical origins and current status. Compr Psychiatry. 1983 May-Jun; 24(3):199-212.
      View in: PubMed
    280. Siever LJ, Pickar D, Lake CR, Cohen RM, Uhde TW, Murphy DL. Extreme elevations in plasma norepinephrine associated with decreased alpha-adrenergic responsiveness in major depressive disorder: two case reports. J Clin Psychopharmacol. 1983 Feb; 3(1):39-41.
      View in: PubMed
    281. Siever LJ, Insel TR, Jimerson DC, Lake CR, Uhde TW, Aloi J, Murphy DL. Growth hormone response to clonidine in obsessive-compulsive patients. Br J Psychiatry. 1983 Feb; 142:184-7.
      View in: PubMed
    282. Siever LJ, Uhde TW, Jimerson DC, Kafka MS, Lake CR, Targum S, Murphy DL. Clinical studies of monoamine receptors in the affective disorders and receptor changes with antidepressant treatment. Prog Neuropsychopharmacol Biol Psychiatry. 1983; 7(2-3):249-61.
      View in: PubMed
    283. Gunderson JG, Siever LJ, Spaulding E. The search for a schizotype. Crossing the border again. Arch Gen Psychiatry. 1983 Jan; 40(1):15-22.
      View in: PubMed
    284. Murphy DL, Cohen RM, Siever LJ, Roy B, Karoum F, Wyatt RJ, Garrick NA, Linnoila M. Clinical and laboratory studies with selective monoamine-oxidase-inhibiting drugs. Implications for hypothesized neurotransmitter changes associated with depression and antidepressant drug effects. Mod Probl Pharmacopsychiatry. 1983; 19:287-303.
      View in: PubMed
    285. Siever LJ, Uhde TW, Insel TR, Kaye WH, Jimerson DC, Lake CR, Kafka M, Targum S, Murphy L. Abnormalities in the primary affective disorders compared to other tricyclic-responsive disorders. Psychopharmacol Bull. 1983; 19(3):435-6.
      View in: PubMed
    286. Risch SC, Janowsky DS, Siever LJ, Judd LL, Rausch JL, Huey LY, Beckman KA, Cohen RM, Murphy DL. Cholinomimetic-induced co-release of prolactin and beta-endorphin in man. Psychopharmacol Bull. 1982 Oct; 18(4):21-5.
      View in: PubMed
    287. Siever LJ, Uhde TW, Insel TR, Roy BF, Murphy DL. Growth hormone response to clonidine unchanged by chronic clorgyline treatment. Psychiatry Res. 1982 Oct; 7(2):139-44.
      View in: PubMed
    288. Lewy AJ, Wehr TA, Rosenthal NE, Nurnberger JI, Siever LJ, Uhde TW, Newsome DA, Becker LE, Markey SP, Kopin IJ, Goodwin FK. Melatonin secretion as a neurobiological "marker" and effects of light in humans. Psychopharmacol Bull. 1982 Oct; 18(4):127-9.
      View in: PubMed
    289. Uhde TW, Boulenger JP, Siever LJ, DuPont RL, Post RM. Animal models of anxiety: implications for research in humans. Psychopharmacol Bull. 1982 Oct; 18(4):47-52.
      View in: PubMed
    290. Uhde TW, Siever LJ, Post RM, Jimerson DC, Boulenger JP, Buchsbaum MS. The relationship of plasma free MHPG to anxiety and psycho-physical pain in normal volunteers. Psychopharmacol Bull. 1982 Oct; 18(4):129-32.
      View in: PubMed
    291. Siever LJ, Uhde TW, Silberman EK, Lake CR, Jimerson DC, Risch SC, Kalin NH, Murphy DL. Evaluation of alpha-adrenergic responsiveness to clonidine challenge and noradrenergic metabolism in the affective disorders and their treatment. Psychopharmacol Bull. 1982 Oct; 18(4):118-9.
      View in: PubMed
    292. Siever LJ, Haier RJ, Coursey RD, Sostek AJ, Murphy DL, Holzman PS, Buchsbaum MS. Smooth pursuit eye tracking impairment: relation to other 'markers' of schizophrenia and psychologic correlates. Arch Gen Psychiatry. 1982 Sep; 39(9):1001-5.
      View in: PubMed
    293. Siever LJ, Uhde TW, Murphy DL. Possible subsensitization of alpha 2-adrenergic receptors by chronic monoamine oxidase inhibitor treatment in psychiatric patients. Psychiatry Res. 1982 Jun; 6(3):293-302.
      View in: PubMed
    294. Risch SC, Janowsky DS, Siever LJ, Judd LJ, Rausch JL, Huey LY, Beckman KA, Cohen RM, Murphy DL. Correlated cholinomimetic-stimulated beta-endorphin and prolactin release in humans. Peptides. 1982 May-Jun; 3(3):319-22.
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    295. Siever LJ, Uhde TW, Silberman EK, Jimerson DC, Aloi JA, Post RM, Murphy DL. Growth hormone response to clonidine as a probe of noradrenergic receptor responsiveness in affective disorder patients and controls. Psychiatry Res. 1982 Apr; 6(2):171-83.
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    296. Siever LJ, Risch SC, Murphy DL. Central cholinergic-adrenergic imbalance in the regulation of affective state. Psychiatry Res. 1981 Aug; 5(1):108-9.
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    297. Siever L, Insel T, Uhde T. Noradrenergic challenges in the affective disorders. J Clin Psychopharmacol. 1981 Jul; 1(4):193-206.
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    298. Insel TR, Siever LJ. The dopamine system challenge in affective disorders: a review of behavioral and neuroendocrine responses. J Clin Psychopharmacol. 1981 Jul; 1(4):207-13.
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    299. Siever LJ, Cohen RM, Murphy DL. Antidepressants and alpha 2-adrenergic autoreceptor desensitization. Am J Psychiatry. 1981 May; 138(5):681-2.
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    300. Siever LJ. The effect of amantadine on prolactin levels and galactorrhea on neuroleptic-treated patients. J Clin Psychopharmacol. 1981 Jan; 1(1):2-7.
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    301. Siever L, Cohen R, Pert A. Assessing pharmacologically induced dopamine receptor sensitivity changes with the Ungerstedt turning model. Psychopharmacology (Berl). 1981; 75(2):212-3.
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    302. Uhde TW, Post RM, Siever LJ, Buchsbaum MS. Clonidine and psychophysical pain. Lancet. 1980 Dec 20-27; 2(8208-8209):1375.
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    303. Cohen RM, Campbell IC, Cohen MR, Torda T, Pickar D, Siever LJ, Murphy DL. Presynaptic noradrenergic regulation during depression and antidepressant drug treatment. Psychiatry Res. 1980 Sep; 3(1):93-105.
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    304. Kafka MS, van Kammen DP, Kleinman JE, Nurnberger JI, Siever LJ, Uhde TW, Polinsky RJ. Alpha-adrenergic receptor function in schizophrenia, affective disorders and some neurological diseases. Commun Psychopharmacol. 1980; 4(6):477-86.
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    305. Siever LJ, Gunderson JG. Genetic determinants of borderline conditions. Schizophr Bull. 1979; 5(1):59-86.
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    306. Siever L, Kraemer H, Sack R, Angwin P, Berger P, Zarcone V, Barchas J, Brodie HK. Gradients of biogenic amine metabolites in cerebrospinal fluid. Dis Nerv Syst. 1975 Jan; 36(1):13-6.
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