Keywords
Last Name
Institution

Dennis S. Charney

TitleDEAN
InstitutionMount Sinai
DepartmentIcahn School of Medicine at Mount Sinai
Address
    Other Positions
    TitlePRESIDENT FOR ACADEMIC AFFAIRS, MOUNT SINAI HEALTH SYSTEM
    InstitutionMount Sinai

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentPsychiatry

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentNeuroscience

    TitlePROFESSOR
    InstitutionMount Sinai
    DepartmentPharmacology and Systems Therapeutics


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Niciu MJ, Henter ID, Luckenbaugh DA, Zarate CA, Charney DS. Glutamate receptor antagonists as fast-acting therapeutic alternatives for the treatment of depression: ketamine and other compounds. Annu Rev Pharmacol Toxicol. 2014 Jan 6; 54:119-39.
      View in: PubMed
    2. Haile CN, Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Foulkes A, Iqbal S, Mahoney JJ, De La Garza R, Charney DS, Newton TF, Mathew SJ. Plasma brain derived neurotrophic factor (BDNF) and response to ketamine in treatment-resistant depression. Int J Neuropsychopharmacol. 2014 Feb; 17(2):331-6.
      View in: PubMed
    3. Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Green CE, Perez AM, Iqbal S, Pillemer S, Foulkes A, Shah A, Charney DS, Mathew SJ. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial. Am J Psychiatry. 2013 Oct 1; 170(10):1134-42.
      View in: PubMed
    4. Wald I, Degnan KA, Gorodetsky E, Charney DS, Fox NA, Fruchter E, Goldman D, Lubin G, Pine DS, Bar-Haim Y. Attention to threats and combat-related posttraumatic stress symptoms: prospective associations and moderation by the serotonin transporter gene. JAMA Psychiatry. 2013 Apr; 70(4):401-8.
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    5. Russo SJ, Charney DS. Next generation antidepressants. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4441-2.
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    6. Nugent AC, Bain EE, Carlson PJ, Neumeister A, Bonne O, Carson RE, Eckelman W, Herscovitch P, Zarate CA, Charney DS, Drevets WC. Reduced post-synaptic serotonin type 1A receptor binding in bipolar depression. Eur Neuropsychopharmacol. 2013 Aug; 23(8):822-9.
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    7. Wu G, Feder A, Cohen H, Kim JJ, Calderon S, Charney DS, Mathé AA. Understanding resilience. Front Behav Neurosci. 2013; 7:10.
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    8. Murrough JW, Charney DS. Is there anything really novel on the antidepressant horizon? Curr Psychiatry Rep. 2012 Dec; 14(6):643-9.
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    9. Feder A, Ahmad S, Lee EJ, Morgan JE, Singh R, Smith BW, Southwick SM, Charney DS. Coping and PTSD symptoms in Pakistani earthquake survivors: purpose in life, religious coping and social support. J Affect Disord. 2013 May; 147(1-3):156-63.
      View in: PubMed
    10. Russo SJ, Murrough JW, Han MH, Charney DS, Nestler EJ. Neurobiology of resilience. Nat Neurosci. 2012 Nov; 15(11):1475-84.
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    11. Southwick SM, Charney DS. The science of resilience: implications for the prevention and treatment of depression. Science. 2012 Oct 5; 338(6103):79-82.
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    12. Murrough JW, Perez AM, Pillemer S, Stern J, Parides MK, aan het Rot M, Collins KA, Mathew SJ, Charney DS, Iosifescu DV. Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression. Biol Psychiatry. 2013 Aug 15; 74(4):250-6.
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    13. Aan Het Rot M, Zarate CA, Charney DS, Mathew SJ. Ketamine for depression: where do we go from here? Biol Psychiatry. 2012 Oct 1; 72(7):537-47.
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    14. Blair KS, Vythilingam M, Crowe SL, McCaffrey DE, Ng P, Wu CC, Scaramozza M, Mondillo K, Pine DS, Charney DS, Blair RJ. Cognitive control of attention is differentially affected in trauma-exposed individuals with and without post-traumatic stress disorder. Psychol Med. 2013 Jan; 43(1):85-95.
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    15. Gold PW, Pavlatou MG, Carlson PJ, Luckenbaugh DA, Costello R, Bonne O, Csako G, Drevets WC, Remaley AT, Charney DS, Neumeister A, Kling MA. Unmedicated, remitted patients with major depression have decreased serum immunoglobulin A. Neurosci Lett. 2012 Jun 27; 520(1):1-5.
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    16. Wu G, Feder A, Wegener G, Bailey C, Saxena S, Charney D, Mathé AA. Central functions of neuropeptide Y in mood and anxiety disorders. Expert Opin Ther Targets. 2011 Nov; 15(11):1317-31.
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    17. Savitz JB, Bonne O, Nugent AC, Vythilingam M, Bogers W, Charney DS, Drevets WC. Habenula volume in post-traumatic stress disorder measured with high-resolution MRI. Biol Mood Anxiety Disord. 2011; 1(1):7.
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    18. Murrough JW, Iacoviello B, Neumeister A, Charney DS, Iosifescu DV. Cognitive dysfunction in depression: neurocircuitry and new therapeutic strategies. Neurobiol Learn Mem. 2011 Nov; 96(4):553-63.
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    19. Murrough JW, Charney DS. The serotonin transporter and emotionality: risk, resilience, and new therapeutic opportunities. Biol Psychiatry. 2011 Mar 15; 69(6):510-2.
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    20. Feder A, Skipper J, Blair JR, Buchholz K, Mathew SJ, Schwarz M, Doucette JT, Alonso A, Collins KA, Neumeister A, Charney DS. Tryptophan depletion and emotional processing in healthy volunteers at high risk for depression. Biol Psychiatry. 2011 Apr 15; 69(8):804-7.
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    21. Wald I, Shechner T, Bitton S, Holoshitz Y, Charney DS, Muller D, Fox NA, Pine DS, Bar-Haim Y. Attention bias away from threat during life threatening danger predicts PTSD symptoms at one-year follow-up. Depress Anxiety. 2011 May; 28(5):406-11.
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    22. Murrough JW, Perez AM, Mathew SJ, Charney DS. A case of sustained remission following an acute course of ketamine in treatment-resistant depression. J Clin Psychiatry. 2011 Mar; 72(3):414-5.
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    23. Mathew SJ, Vythilingam M, Murrough JW, Zarate CA, Feder A, Luckenbaugh DA, Kinkead B, Parides MK, Trist DG, Bani MS, Bettica PU, Ratti EM, Charney DS. A selective neurokinin-1 receptor antagonist in chronic PTSD: a randomized, double-blind, placebo-controlled, proof-of-concept trial. Eur Neuropsychopharmacol. 2011 Mar; 21(3):221-9.
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    24. Bonne O, Gill JM, Luckenbaugh DA, Collins C, Owens MJ, Alesci S, Neumeister A, Yuan P, Kinkead B, Manji HK, Charney DS, Vythilingam M. Corticotropin-releasing factor, interleukin-6, brain-derived neurotrophic factor, insulin-like growth factor-1, and substance P in the cerebrospinal fluid of civilians with posttraumatic stress disorder before and after treatment with paroxetine. J Clin Psychiatry. 2011 Aug; 72(8):1124-8.
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    25. Murrough JW, Charney DS. Cracking the moody brain: lifting the mood with ketamine. Nat Med. 2010 Dec; 16(12):1384-5.
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    26. Wald I, Lubin G, Holoshitz Y, Muller D, Fruchter E, Pine DS, Charney DS, Bar-Haim Y. Battlefield-like stress following simulated combat and suppression of attention bias to threat. Psychol Med. 2011 Apr; 41(4):699-707.
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    27. Savitz JB, Nugent AC, Bogers W, Roiser JP, Bain EE, Neumeister A, Zarate CA, Manji HK, Cannon DM, Marrett S, Henn F, Charney DS, Drevets WC. Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study. Biol Psychiatry. 2011 Feb 15; 69(4):336-43.
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    28. Gill J, Luckenbaugh D, Charney D, Vythilingam M. Sustained elevation of serum interleukin-6 and relative insensitivity to hydrocortisone differentiates posttraumatic stress disorder with and without depression. Biol Psychiatry. 2010 Dec 1; 68(11):999-1006.
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    29. Krystal JH, Mathew SJ, D'Souza DC, Garakani A, Gunduz-Bruce H, Charney DS. Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists. CNS Drugs. 2010 Aug; 24(8):669-93.
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    30. Ahmad S, Feder A, Lee EJ, Wang Y, Southwick SM, Schlackman E, Buchholz K, Alonso A, Charney DS. Earthquake impact in a remote South Asian population: psychosocial factors and posttraumatic symptoms. J Trauma Stress. 2010 Jun; 23(3):408-12.
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    31. Bar-Haim Y, Holoshitz Y, Eldar S, Frenkel TI, Muller D, Charney DS, Pine DS, Fox NA, Wald I. Life-threatening danger and suppression of attention bias to threat. Am J Psychiatry. 2010 Jun; 167(6):694-8.
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    32. aan het Rot M, Collins KA, Murrough JW, Perez AM, Reich DL, Charney DS, Mathew SJ. Safety and efficacy of repeated-dose intravenous ketamine for treatment-resistant depression. Biol Psychiatry. 2010 Jan 15; 67(2):139-45.
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    33. Zuo L, Luo X, Kranzler HR, Lu L, Rosenheck RA, Cramer J, van Kammen DP, Erdos J, Charney DS, Krystal J, Gelernter J. Association study of DTNBP1 with schizophrenia in a US sample. Psychiatr Genet. 2009 Dec; 19(6):292-304.
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    34. Savitz J, Nugent AC, Bogers W, Liu A, Sills R, Luckenbaugh DA, Bain EE, Price JL, Zarate C, Manji HK, Cannon DM, Marrett S, Charney DS, Drevets WC. Amygdala volume in depressed patients with bipolar disorder assessed using high resolution 3T MRI: the impact of medication. Neuroimage. 2010 Feb 15; 49(4):2966-76.
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    35. Iyengar R, Wang Y, Chow J, Charney DS. An integrated approach to evaluate faculty members' research performance. Acad Med. 2009 Nov; 84(11):1610-6.
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    36. Vythilingam M, Gill JM, Luckenbaugh DA, Gold PW, Collin C, Bonne O, Plumb K, Polignano E, West K, Charney D. Low early morning plasma cortisol in posttraumatic stress disorder is associated with co-morbid depression but not with enhanced glucocorticoid feedback inhibition. Psychoneuroendocrinology. 2010 Apr; 35(3):442-50.
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    37. Price RB, Nock MK, Charney DS, Mathew SJ. Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatment-resistant depression. Biol Psychiatry. 2009 Sep 1; 66(5):522-6.
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    38. New AS, Fan J, Murrough JW, Liu X, Liebman RE, Guise KG, Tang CY, Charney DS. A functional magnetic resonance imaging study of deliberate emotion regulation in resilience and posttraumatic stress disorder. Biol Psychiatry. 2009 Oct 1; 66(7):656-64.
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    39. Feder A, Nestler EJ, Charney DS. Psychobiology and molecular genetics of resilience. Nat Rev Neurosci. 2009 Jun; 10(6):446-57.
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    40. Zuo L, Luo X, Krystal JH, Cramer J, Charney DS, Gelernter J. The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation. Pharmacogenet Genomics. 2009 Jun; 19(6):437-46.
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    41. Hasler G, Luckenbaugh DA, Snow J, Meyers N, Waldeck T, Geraci M, Roiser J, Knutson B, Charney DS, Drevets WC. Reward processing after catecholamine depletion in unmedicated, remitted subjects with major depressive disorder. Biol Psychiatry. 2009 Aug 1; 66(3):201-5.
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    42. Zuo L, Luo X, Listman JB, Kranzler HR, Wang S, Anton RF, Blumberg HP, Stein MB, Pearlson GD, Covault J, Charney DS, van Kammen DP, Price LH, Lappalainen J, Cramer J, Krystal JH, Gelernter J. Population admixture modulates risk for alcohol dependence. Hum Genet. 2009 Jun; 125(5-6):605-13.
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    43. Mathew SJ, Murrough JW, aan het Rot M, Collins KA, Reich DL, Charney DS. Riluzole for relapse prevention following intravenous ketamine in treatment-resistant depression: a pilot randomized, placebo-controlled continuation trial. Int J Neuropsychopharmacol. 2010 Feb; 13(1):71-82.
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    44. Vasa RA, Pine DS, Masten CL, Vythilingam M, Collin C, Charney DS, Neumeister A, Mogg K, Bradley BP, Bruck M, Monk CS. Effects of yohimbine and hydrocortisone on panic symptoms, autonomic responses, and attention to threat in healthy adults. Psychopharmacology (Berl). 2009 Jun; 204(3):445-55.
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    45. Vythilingam M, Nelson EE, Scaramozza M, Waldeck T, Hazlett G, Southwick SM, Pine DS, Drevets W, Charney DS, Ernst M. Reward circuitry in resilience to severe trauma: an fMRI investigation of resilient special forces soldiers. Psychiatry Res. 2009 Apr 30; 172(1):75-7.
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    46. aan het Rot M, Mathew SJ, Charney DS. Neurobiological mechanisms in major depressive disorder. CMAJ. 2009 Feb 3; 180(3):305-13.
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    47. Haglund ME, aan het Rot M, Cooper NS, Nestadt PS, Muller D, Southwick SM, Charney DS. Resilience in the third year of medical school: a prospective study of the associations between stressful events occurring during clinical rotations and student well-being. Acad Med. 2009 Feb; 84(2):258-68.
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    48. Mathew SJ, Charney DS. Publication bias and the efficacy of antidepressants. Am J Psychiatry. 2009 Feb; 166(2):140-5.
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    49. Mellman TA, Alim T, Brown DD, Gorodetsky E, Buzas B, Lawson WB, Goldman D, Charney DS. Serotonin polymorphisms and posttraumatic stress disorder in a trauma exposed African American population. Depress Anxiety. 2009; 26(11):993-7.
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    50. Price RB, Shungu DC, Mao X, Nestadt P, Kelly C, Collins KA, Murrough JW, Charney DS, Mathew SJ. Amino acid neurotransmitters assessed by proton magnetic resonance spectroscopy: relationship to treatment resistance in major depressive disorder. Biol Psychiatry. 2009 May 1; 65(9):792-800.
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    51. Alim TN, Feder A, Graves RE, Wang Y, Weaver J, Westphal M, Alonso A, Aigbogun NU, Smith BW, Doucette JT, Mellman TA, Lawson WB, Charney DS. Trauma, resilience, and recovery in a high-risk African-American population. Am J Psychiatry. 2008 Dec; 165(12):1566-75.
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    52. Stellman JM, Smith RP, Katz CL, Sharma V, Charney DS, Herbert R, Moline J, Luft BJ, Markowitz S, Udasin I, Harrison D, Baron S, Landrigan PJ, Levin SM, Southwick S. Enduring mental health morbidity and social function impairment in world trade center rescue, recovery, and cleanup workers: the psychological dimension of an environmental health disaster. Environ Health Perspect. 2008 Sep; 116(9):1248-53.
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    53. Ozbay F, Fitterling H, Charney D, Southwick S. Social support and resilience to stress across the life span: a neurobiologic framework. Curr Psychiatry Rep. 2008 Aug; 10(4):304-10.
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    54. Nugent AC, Neumeister A, Goldman D, Herscovitch P, Charney DS, Drevets WC. Serotonin transporter genotype and depressive phenotype determination by discriminant analysis of glucose metabolism under acute tryptophan depletion. Neuroimage. 2008 Dec; 43(4):764-74.
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    55. Bonne O, Vythilingam M, Inagaki M, Wood S, Neumeister A, Nugent AC, Snow J, Luckenbaugh DA, Bain EE, Drevets WC, Charney DS. Reduced posterior hippocampal volume in posttraumatic stress disorder. J Clin Psychiatry. 2008 Jul; 69(7):1087-91.
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    56. New AS, Triebwasser J, Charney DS. The case for shifting borderline personality disorder to Axis I. Biol Psychiatry. 2008 Oct 15; 64(8):653-9.
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    57. Mathew SJ, Price RB, Charney DS. Recent advances in the neurobiology of anxiety disorders: implications for novel therapeutics. Am J Med Genet C Semin Med Genet. 2008 May 15; 148C(2):89-98.
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    58. Blair K, Shaywitz J, Smith BW, Rhodes R, Geraci M, Jones M, McCaffrey D, Vythilingam M, Finger E, Mondillo K, Jacobs M, Charney DS, Blair RJ, Drevets WC, Pine DS. Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders. Am J Psychiatry. 2008 Sep; 165(9):1193-202.
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    59. Mathew S, Charney D. Anxiety and depression: leading edge of therapy. Mt Sinai J Med. 2008 May-Jun; 75(3):171-3.
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    60. Hasler G, Fromm S, Carlson PJ, Luckenbaugh DA, Waldeck T, Geraci M, Roiser JP, Neumeister A, Meyers N, Charney DS, Drevets WC. Neural response to catecholamine depletion in unmedicated subjects with major depressive disorder in remission and healthy subjects. Arch Gen Psychiatry. 2008 May; 65(5):521-31.
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    61. Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA, Cook EH, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biol Psychiatry. 2008 Apr 15; 63(8):725-7.
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    62. Jacobs M, Snow J, Geraci M, Vythilingam M, Blair RJ, Charney DS, Pine DS, Blair KS. Association between level of emotional intelligence and severity of anxiety in generalized social phobia. J Anxiety Disord. 2008 Dec; 22(8):1487-95.
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    63. Horn TL, Harder JB, Johnson WD, Curry PT, Parchment RE, Morrissey RL, Mellick PW, Calis KA, Gold PW, Rice KC, Contoreggi C, Charney DS, Cizza G, Glaze ER, Tomaszewski JE, McCormick DL. Integration of in vivo and in vitro approaches to characterize the toxicity of Antalarmin, a corticotropin-releasing hormone receptor antagonist. Toxicology. 2008 Jun 3; 248(1):8-17.
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    64. Bills CB, Levy NA, Sharma V, Charney DS, Herbert R, Moline J, Katz CL. Mental health of workers and volunteers responding to events of 9/11: review of the literature. Mt Sinai J Med. 2008 Mar-Apr; 75(2):115-27.
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    65. Czermak C, Hauger R, Drevets WC, Luckenbaugh DA, Geraci M, Charney DS, Neumeister A. Plasma NPY concentrations during tryptophan and sham depletion in medication-free patients with remitted depression. J Affect Disord. 2008 Oct; 110(3):277-81.
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    66. Krishnamurthy P, Romagni P, Torvik S, Gold PW, Charney DS, Detera-Wadleigh S, Cizza G. Glucocorticoid receptor gene polymorphisms in premenopausal women with major depression. Horm Metab Res. 2008 Mar; 40(3):194-8.
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    67. Lekman M, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji H, McMahon FJ, Paddock S. The FKBP5-gene in depression and treatment response--an association study in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Cohort. Biol Psychiatry. 2008 Jun 15; 63(12):1103-10.
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    68. Mathew SJ, Manji HK, Charney DS. Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology. 2008 Aug; 33(9):2080-92.
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    69. Feder A, Southwick SM, Goetz RR, Wang Y, Alonso A, Smith BW, Buchholz KR, Waldeck T, Ameli R, Moore J, Hain R, Charney DS, Vythilingam M. Posttraumatic growth in former Vietnam prisoners of war. Psychiatry. 2008; 71(4):359-70.
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    70. Masten CL, Guyer AE, Hodgdon HB, McClure EB, Charney DS, Ernst M, Kaufman J, Pine DS, Monk CS. Recognition of facial emotions among maltreated children with high rates of post-traumatic stress disorder. Child Abuse Negl. 2008 Jan; 32(1):139-53.
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    71. Mathew SJ, Price RB, Mao X, Smith EL, Coplan JD, Charney DS, Shungu DC. Hippocampal N-acetylaspartate concentration and response to riluzole in generalized anxiety disorder. Biol Psychiatry. 2008 May 1; 63(9):891-8.
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    72. Laje G, Paddock S, Manji H, Rush AJ, Wilson AF, Charney D, McMahon FJ. Genetic markers of suicidal ideation emerging during citalopram treatment of major depression. Am J Psychiatry. 2007 Oct; 164(10):1530-8.
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    73. Cannon DM, Ichise M, Rollis D, Klaver JM, Gandhi SK, Charney DS, Manji HK, Drevets WC. Elevated serotonin transporter binding in major depressive disorder assessed using positron emission tomography and [11C]DASB; comparison with bipolar disorder. Biol Psychiatry. 2007 Oct 15; 62(8):870-7.
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    74. Paddock S, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji H, McMahon FJ. Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort. Am J Psychiatry. 2007 Aug; 164(8):1181-8.
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    75. Hu XZ, Rush AJ, Charney D, Wilson AF, Sorant AJ, Papanicolaou GJ, Fava M, Trivedi MH, Wisniewski SR, Laje G, Paddock S, McMahon FJ, Manji H, Lipsky RH. Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. Arch Gen Psychiatry. 2007 Jul; 64(7):783-92.
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    76. Vythilingam M, Blair KS, McCaffrey D, Scaramozza M, Jones M, Nakic M, Mondillo K, Hadd K, Bonne O, Mitchell DG, Pine DS, Charney DS, Blair RJ. Biased emotional attention in post-traumatic stress disorder: a help as well as a hindrance? Psychol Med. 2007 Oct; 37(10):1445-55.
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    77. Graves RE, Alim TN, Aigbogun N, Chrishon K, Mellman TA, Charney DS, Lawson WB. Diagnosing bipolar disorder in trauma exposed primary care patients. Bipolar Disord. 2007 Jun; 9(4):318-23.
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    78. Ozbay F, Johnson DC, Dimoulas E, Morgan CA, Charney D, Southwick S. Social support and resilience to stress: from neurobiology to clinical practice. Psychiatry (Edgmont). 2007 May; 4(5):35-40.
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    79. Nemeroff CB, Kalali A, Keller MB, Charney DS, Lenderts SE, Cascade EF, Stephenson H, Schatzberg AF. Impact of publicity concerning pediatric suicidality data on physician practice patterns in the United States. Arch Gen Psychiatry. 2007 Apr; 64(4):466-72.
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    80. McClure EB, Monk CS, Nelson EE, Parrish JM, Adler A, Blair RJ, Fromm S, Charney DS, Leibenluft E, Ernst M, Pine DS. Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder. Arch Gen Psychiatry. 2007 Jan; 64(1):97-106.
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    81. Haglund ME, Nestadt PS, Cooper NS, Southwick SM, Charney DS. Psychobiological mechanisms of resilience: relevance to prevention and treatment of stress-related psychopathology. Dev Psychopathol. 2007; 19(3):889-920.
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    82. Bremner JD, Vythilingam M, Vermetten E, Charney DS. Effects of antidepressant treatment on neural correlates of emotional and neutral declarative verbal memory in depression. J Affect Disord. 2007 Aug; 101(1-3):99-111.
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    83. Kling MA, Alesci S, Csako G, Costello R, Luckenbaugh DA, Bonne O, Duncko R, Drevets WC, Manji HK, Charney DS, Gold PW, Neumeister A. Sustained low-grade pro-inflammatory state in unmedicated, remitted women with major depressive disorder as evidenced by elevated serum levels of the acute phase proteins C-reactive protein and serum amyloid A. Biol Psychiatry. 2007 Aug 15; 62(4):309-13.
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    84. Garakani A, Mathew SJ, Charney DS. Neurobiology of anxiety disorders and implications for treatment. Mt Sinai J Med. 2006 Nov; 73(7):941-9.
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    85. Alim TN, Graves E, Mellman TA, Aigbogun N, Gray E, Lawson W, Charney DS. Trauma exposure, posttraumatic stress disorder and depression in an African-American primary care population. J Natl Med Assoc. 2006 Oct; 98(10):1630-6.
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    86. Neumeister A, Hu XZ, Luckenbaugh DA, Schwarz M, Nugent AC, Bonne O, Herscovitch P, Goldman D, Drevets WC, Charney DS. Differential effects of 5-HTTLPR genotypes on the behavioral and neural responses to tryptophan depletion in patients with major depression and controls. Arch Gen Psychiatry. 2006 Sep; 63(9):978-86.
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    87. Rasmusson AM, Pinna G, Paliwal P, Weisman D, Gottschalk C, Charney D, Krystal J, Guidotti A. Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder. Biol Psychiatry. 2006 Oct 1; 60(7):704-13.
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    88. Cannon DM, Ichise M, Fromm SJ, Nugent AC, Rollis D, Gandhi SK, Klaver JM, Charney DS, Manji HK, Drevets WC. Serotonin transporter binding in bipolar disorder assessed using [11C]DASB and positron emission tomography. Biol Psychiatry. 2006 Aug 1; 60(3):207-17.
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    89. Zarate CA, Singh JB, Carlson PJ, Brutsche NE, Ameli R, Luckenbaugh DA, Charney DS, Manji HK. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Arch Gen Psychiatry. 2006 Aug; 63(8):856-64.
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    90. Alim TN, Charney DS, Mellman TA. An overview of posttraumatic stress disorder in African Americans. J Clin Psychol. 2006 Jul; 62(7):801-13.
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    91. Vermetten E, Vythilingam M, Schmahl C, DE Kloet C, Southwick SM, Charney DS, Bremner JD. Alterations in stress reactivity after long-term treatment with paroxetine in women with posttraumatic stress disorder. Ann N Y Acad Sci. 2006 Jul; 1071:184-202.
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    92. Yehuda R, Flory JD, Southwick S, Charney DS. Developing an agenda for translational studies of resilience and vulnerability following trauma exposure. Ann N Y Acad Sci. 2006 Jul; 1071:379-96.
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    93. Kaplan JS, Erickson K, Luckenbaugh DA, Weiland-Fiedler P, Geraci M, Sahakian BJ, Charney D, Drevets WC, Neumeister A. Differential performance on tasks of affective processing and decision-making in patients with Panic Disorder and Panic Disorder with comorbid Major Depressive Disorder. J Affect Disord. 2006 Oct; 95(1-3):165-71.
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    94. Zhang H, Ozbay F, Lappalainen J, Kranzler HR, van Dyck CH, Charney DS, Price LH, Southwick S, Yang BZ, Rasmussen A, Gelernter J. Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence. Am J Med Genet B Neuropsychiatr Genet. 2006 Jun 5; 141B(4):387-93.
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    95. Monk CS, Nelson EE, McClure EB, Mogg K, Bradley BP, Leibenluft E, Blair RJ, Chen G, Charney DS, Ernst M, Pine DS. Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder. Am J Psychiatry. 2006 Jun; 163(6):1091-7.
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    96. Nemeroff CB, Mayberg HS, Krahl SE, McNamara J, Frazer A, Henry TR, George MS, Charney DS, Brannan SK. VNS therapy in treatment-resistant depression: clinical evidence and putative neurobiological mechanisms. Neuropsychopharmacology. 2006 Jul; 31(7):1345-55.
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    97. Roberson-Nay R, McClure EB, Monk CS, Nelson EE, Guyer AE, Fromm SJ, Charney DS, Leibenluft E, Blair J, Ernst M, Pine DS. Increased amygdala activity during successful memory encoding in adolescent major depressive disorder: An FMRI study. Biol Psychiatry. 2006 Nov 1; 60(9):966-73.
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    98. McMahon FJ, Buervenich S, Charney D, Lipsky R, Rush AJ, Wilson AF, Sorant AJ, Papanicolaou GJ, Laje G, Fava M, Trivedi MH, Wisniewski SR, Manji H. Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. Am J Hum Genet. 2006 May; 78(5):804-14.
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    99. Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, Martin L, Gerard E, Charney DS, Peterson BS. Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study. Biol Psychiatry. 2006 Apr 1; 59(7):611-8.
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    100. Neumeister A, Drevets WC, Belfer I, Luckenbaugh DA, Henry S, Bonne O, Herscovitch P, Goldman D, Charney DS. Effects of a alpha 2C-adrenoreceptor gene polymorphism on neural responses to facial expressions in depression. Neuropsychopharmacology. 2006 Aug; 31(8):1750-6.
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    101. Zarate CA, Singh JB, Quiroz JA, De Jesus G, Denicoff KK, Luckenbaugh DA, Manji HK, Charney DS. A double-blind, placebo-controlled study of memantine in the treatment of major depression. Am J Psychiatry. 2006 Jan; 163(1):153-5.
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    102. Vythilingam M, Lawley M, Collin C, Bonne O, Agarwal R, Hadd K, Charney DS, Grillon C. Hydrocortisone impairs hippocampal-dependent trace eyeblink conditioning in post-traumatic stress disorder. Neuropsychopharmacology. 2006 Jan; 31(1):182-8.
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    103. Zhou Z, Peters EJ, Hamilton SP, McMahon F, Thomas C, McGrath PJ, Rush J, Trivedi MH, Charney DS, Roy A, Wisniewski S, Lipsky R, Goldman D. Response to Zhang et al. (2005): loss-of-function mutation in tryptophan hydroxylase-2 identified in unipolar major depression. Neuron 45, 11-16. Neuron. 2005 Dec 8; 48(5):702-3; author reply 705-6.
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    104. Erickson K, Drevets WC, Clark L, Cannon DM, Bain EE, Zarate CA, Charney DS, Sahakian BJ. Mood-congruent bias in affective go/no-go performance of unmedicated patients with major depressive disorder. Am J Psychiatry. 2005 Nov; 162(11):2171-3.
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    105. McClure EB, Treland JE, Snow J, Schmajuk M, Dickstein DP, Towbin KE, Charney DS, Pine DS, Leibenluft E. Deficits in social cognition and response flexibility in pediatric bipolar disorder. Am J Psychiatry. 2005 Sep; 162(9):1644-51.
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    106. Staley JK, Sanacora G, Tamagnan G, Maciejewski PK, Malison RT, Berman RM, Vythilingam M, Kugaya A, Baldwin RM, Seibyl JP, Charney D, Innis RB. Sex differences in diencephalon serotonin transporter availability in major depression. Biol Psychiatry. 2006 Jan 1; 59(1):40-7.
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    107. Evans DL, Charney DS, Lewis L, Golden RN, Gorman JM, Krishnan KR, Nemeroff CB, Bremner JD, Carney RM, Coyne JC, Delong MR, Frasure-Smith N, Glassman AH, Gold PW, Grant I, Gwyther L, Ironson G, Johnson RL, Kanner AM, Katon WJ, Kaufmann PG, Keefe FJ, Ketter T, Laughren TP, Leserman J, Lyketsos CG, McDonald WM, McEwen BS, Miller AH, Musselman D, O'Connor C, Petitto JM, Pollock BG, Robinson RG, Roose SP, Rowland J, Sheline Y, Sheps DS, Simon G, Spiegel D, Stunkard A, Sunderland T, Tibbits P, Valvo WJ. Mood disorders in the medically ill: scientific review and recommendations. Biol Psychiatry. 2005 Aug 1; 58(3):175-89.
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    108. Easter J, McClure EB, Monk CS, Dhanani M, Hodgdon H, Leibenluft E, Charney DS, Pine DS, Ernst M. Emotion recognition deficits in pediatric anxiety disorders: implications for amygdala research. J Child Adolesc Psychopharmacol. 2005 Aug; 15(4):563-70.
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    109. Vythilingam M, Luckenbaugh DA, Lam T, Morgan CA, Lipschitz D, Charney DS, Bremner JD, Southwick SM. Smaller head of the hippocampus in Gulf War-related posttraumatic stress disorder. Psychiatry Res. 2005 Jul 30; 139(2):89-99.
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    110. Grillon C, Pine DS, Baas JM, Lawley M, Ellis V, Charney DS. Cortisol and DHEA-S are associated with startle potentiation during aversive conditioning in humans. Psychopharmacology (Berl). 2006 Jun; 186(3):434-41.
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    111. Hasler G, Neumeister A, van der Veen JW, Tumonis T, Bain EE, Shen J, Drevets WC, Charney DS. Normal prefrontal gamma-aminobutyric acid levels in remitted depressed subjects determined by proton magnetic resonance spectroscopy. Biol Psychiatry. 2005 Dec 15; 58(12):969-73.
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    112. Dickstein DP, Milham MP, Nugent AC, Drevets WC, Charney DS, Pine DS, Leibenluft E. Frontotemporal alterations in pediatric bipolar disorder: results of a voxel-based morphometry study. Arch Gen Psychiatry. 2005 Jul; 62(7):734-41.
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    113. Bremner JD, Vermetten E, Schmahl C, Vaccarino V, Vythilingam M, Afzal N, Grillon C, Charney DS. Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder. Psychol Med. 2005 Jun; 35(6):791-806.
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    114. Neumeister A, Charney DS, Drevets WC. Hippocampus, VI. Depression and the Hippocampus. Am J Psychiatry. 2005 Jun; 162(6):1057.
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    115. Gold PW, Wong ML, Goldstein DS, Gold HK, Ronsaville DS, Esler M, Alesci S, Masood A, Licinio J, Geracioti TD, Perini G, DeBellis MD, Holmes C, Vgontzas AN, Charney DS, Chrousos GP, McCann SM, Kling MA. Cardiac implications of increased arterial entry and reversible 24-h central and peripheral norepinephrine levels in melancholia. Proc Natl Acad Sci U S A. 2005 Jun 7; 102(23):8303-8.
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    116. McClure EB, Treland JE, Snow J, Dickstein DP, Towbin KE, Charney DS, Pine DS, Leibenluft E. Memory and learning in pediatric bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2005 May; 44(5):461-9.
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    117. Milham MP, Nugent AC, Drevets WC, Dickstein DP, Leibenluft E, Ernst M, Charney D, Pine DS. Selective reduction in amygdala volume in pediatric anxiety disorders: a voxel-based morphometry investigation. Biol Psychiatry. 2005 May 1; 57(9):961-6.
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    118. Neumeister A, Wood S, Bonne O, Nugent AC, Luckenbaugh DA, Young T, Bain EE, Charney DS, Drevets WC. Reduced hippocampal volume in unmedicated, remitted patients with major depression versus control subjects. Biol Psychiatry. 2005 Apr 15; 57(8):935-7.
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    119. Neumeister A, Yuan P, Young TA, Bonne O, Luckenbaugh DA, Charney DS, Manji H. Effects of tryptophan depletion on serum levels of brain-derived neurotrophic factor in unmedicated patients with remitted depression and healthy subjects. Am J Psychiatry. 2005 Apr; 162(4):805-7.
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    120. Neumeister A, Charney DS, Belfer I, Geraci M, Holmes C, Sharabi Y, Alim T, Bonne O, Luckenbaugh DA, Manji H, Goldman D, Goldstein DS. Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans. Pharmacogenet Genomics. 2005 Mar; 15(3):143-9.
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    121. Zarate CA, Quiroz JA, Singh JB, Denicoff KD, De Jesus G, Luckenbaugh DA, Charney DS, Manji HK. An open-label trial of the glutamate-modulating agent riluzole in combination with lithium for the treatment of bipolar depression. Biol Psychiatry. 2005 Feb 15; 57(4):430-2.
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    122. Bonne O, Bain E, Neumeister A, Nugent AC, Vythilingam M, Carson RE, Luckenbaugh DA, Eckelman W, Herscovitch P, Drevets WC, Charney DS. No change in serotonin type 1A receptor binding in patients with posttraumatic stress disorder. Am J Psychiatry. 2005 Feb; 162(2):383-5.
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    123. Pine DS, Mogg K, Bradley BP, Montgomery L, Monk CS, McClure E, Guyer AE, Ernst M, Charney DS, Kaufman J. Attention bias to threat in maltreated children: implications for vulnerability to stress-related psychopathology. Am J Psychiatry. 2005 Feb; 162(2):291-6.
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    124. Neumeister A, Daher RJ, Charney DS. Anxiety disorders: noradrenergic neurotransmission. Handb Exp Pharmacol. 2005; (169):205-23.
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    125. Southwick SM, Vythilingam M, Charney DS. The psychobiology of depression and resilience to stress: implications for prevention and treatment. Annu Rev Clin Psychol. 2005; 1:255-91.
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    126. Bremner JD, Vythilingam M, Vermetten E, Afzal N, Nazeer A, Newcomer JW, Charney DS. Effects of dexamethasone on declarative memory function in posttraumatic stress disorder. Psychiatry Res. 2004 Nov 30; 129(1):1-10.
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    127. O'Brien CP, Charney DS, Lewis L, Cornish JW, Post RM, Woody GE, Zubieta JK, Anthony JC, Blaine JD, Bowden CL, Calabrese JR, Carroll K, Kosten T, Rounsaville B, Childress AR, Oslin DW, Pettinati HM, Davis MA, Demartino R, Drake RE, Fleming MF, Fricks L, Glassman AH, Levin FR, Nunes EV, Johnson RL, Jordan C, Kessler RC, Laden SK, Regier DA, Renner JA, Ries RK, Sklar-Blake T, Weisner C. Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to action. Biol Psychiatry. 2004 Nov 15; 56(10):703-13.
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    128. Monk CS, Nelson EE, Woldehawariat G, Montgomery LA, Zarahn E, McClure EB, Guyer AE, Leibenluft E, Charney DS, Ernst M, Pine DS. Experience-dependent plasticity for attention to threat: Behavioral and neurophysiological evidence in humans. Biol Psychiatry. 2004 Oct 15; 56(8):607-10.
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    129. Weiland-Fiedler P, Erickson K, Waldeck T, Luckenbaugh DA, Pike D, Bonne O, Charney DS, Neumeister A. Evidence for continuing neuropsychological impairments in depression. J Affect Disord. 2004 Oct 15; 82(2):253-8.
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    130. Kugaya A, Sanacora G, Staley JK, Malison RT, Bozkurt A, Khan S, Anand A, Van Dyck CH, Baldwin RM, Seibyl JP, Charney D, Innis RB. Brain serotonin transporter availability predicts treatment response to selective serotonin reuptake inhibitors. Biol Psychiatry. 2004 Oct 1; 56(7):497-502.
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    131. Hasler G, Drevets WC, Manji HK, Charney DS. Discovering endophenotypes for major depression. Neuropsychopharmacology. 2004 Oct; 29(10):1765-81.
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    132. Grillon C, Cordova J, Morgan CA, Charney DS, Davis M. Effects of the beta-blocker propranolol on cued and contextual fear conditioning in humans. Psychopharmacology (Berl). 2004 Sep; 175(3):342-52.
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    133. Rasmusson AM, Vasek J, Lipschitz DS, Vojvoda D, Mustone ME, Shi Q, Gudmundsen G, Morgan CA, Wolfe J, Charney DS. An increased capacity for adrenal DHEA release is associated with decreased avoidance and negative mood symptoms in women with PTSD. Neuropsychopharmacology. 2004 Aug; 29(8):1546-57.
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    134. Neumeister A, Nugent AC, Waldeck T, Geraci M, Schwarz M, Bonne O, Bain EE, Luckenbaugh DA, Herscovitch P, Charney DS, Drevets WC. Neural and behavioral responses to tryptophan depletion in unmedicated patients with remitted major depressive disorder and controls. Arch Gen Psychiatry. 2004 Aug; 61(8):765-73.
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    135. Morgan CA, Southwick S, Hazlett G, Rasmusson A, Hoyt G, Zimolo Z, Charney D. Relationships among plasma dehydroepiandrosterone sulfate and cortisol levels, symptoms of dissociation, and objective performance in humans exposed to acute stress. Arch Gen Psychiatry. 2004 Aug; 61(8):819-25.
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    136. Cheema SR, Arif F, Charney D, Meisels IS, Cheema SS. IgA-dominant glomerulonephritis associated with hepatitis A. Clin Nephrol. 2004 Aug; 62(2):138-43.
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    137. Vythilingam M, Vermetten E, Anderson GM, Luckenbaugh D, Anderson ER, Snow J, Staib LH, Charney DS, Bremner JD. Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment. Biol Psychiatry. 2004 Jul 15; 56(2):101-12.
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    138. Zarate CA, Payne JL, Singh J, Quiroz JA, Luckenbaugh DA, Denicoff KD, Charney DS, Manji HK. Pramipexole for bipolar II depression: a placebo-controlled proof of concept study. Biol Psychiatry. 2004 Jul 1; 56(1):54-60.
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    139. McClure EB, Monk CS, Nelson EE, Zarahn E, Leibenluft E, Bilder RM, Charney DS, Ernst M, Pine DS. A developmental examination of gender differences in brain engagement during evaluation of threat. Biol Psychiatry. 2004 Jun 1; 55(11):1047-55.
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    140. Blumberg HP, Kaufman J, Martin A, Charney DS, Krystal JH, Peterson BS. Significance of adolescent neurodevelopment for the neural circuitry of bipolar disorder. Ann N Y Acad Sci. 2004 Jun; 1021:376-83.
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    141. Sanacora G, Berman RM, Cappiello A, Oren DA, Kugaya A, Liu N, Gueorguieva R, Fasula D, Charney DS. Addition of the alpha2-antagonist yohimbine to fluoxetine: effects on rate of antidepressant response. Neuropsychopharmacology. 2004 Jun; 29(6):1166-71.
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    142. Charney DS, Dejesus G, Manji HK. Cellular plasticity and resilience and the pathophysiology of severe mood disorders. Dialogues Clin Neurosci. 2004 Jun; 6(2):217-25.
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    143. Bremner JD, Vythilingam M, Vermetten E, Anderson G, Newcomer JW, Charney DS. Effects of glucocorticoids on declarative memory function in major depression. Biol Psychiatry. 2004 Apr 15; 55(8):811-5.
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    144. Bremner JD, Vythilingam M, Vermetten E, Vaccarino V, Charney DS. Deficits in hippocampal and anterior cingulate functioning during verbal declarative memory encoding in midlife major depression. Am J Psychiatry. 2004 Apr; 161(4):637-45.
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    145. Charney DS, Manji HK. Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention. Sci STKE. 2004 Mar 23; 2004(225):re5.
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    146. Bremner JD, Vermetten E, Vythilingam M, Afzal N, Schmahl C, Elzinga B, Charney DS. Neural correlates of the classic color and emotional stroop in women with abuse-related posttraumatic stress disorder. Biol Psychiatry. 2004 Mar 15; 55(6):612-20.
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    147. Bonne O, Grillon C, Vythilingam M, Neumeister A, Charney DS. Adaptive and maladaptive psychobiological responses to severe psychological stress: implications for the discovery of novel pharmacotherapy. Neurosci Biobehav Rev. 2004 Mar; 28(1):65-94.
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    148. Luo X, Kranzler H, Lappalainen J, Rosenheck R, Charney D, Zuo L, Erdos J, van Kammen DP, Gelernter J. CALCYON gene variation, schizophrenia, and cocaine dependence. Am J Med Genet B Neuropsychiatr Genet. 2004 Feb 15; 125B(1):25-30.
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    149. Perry EB, Berman RM, Sanacora G, Anand A, Lynch-Colonese K, Charney DS. Pindolol augmentation in depressed patients resistant to selective serotonin reuptake inhibitors: a double-blind, randomized, controlled trial. J Clin Psychiatry. 2004 Feb; 65(2):238-43.
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    150. Charney DS. Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress. Am J Psychiatry. 2004 Feb; 161(2):195-216.
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    151. Neumeister A, Bain E, Nugent AC, Carson RE, Bonne O, Luckenbaugh DA, Eckelman W, Herscovitch P, Charney DS, Drevets WC. Reduced serotonin type 1A receptor binding in panic disorder. J Neurosci. 2004 Jan 21; 24(3):589-91.
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    152. Luo X, Klempan TA, Lappalainen J, Rosenheck RA, Charney DS, Erdos J, van Kammen DP, Kranzler HR, Kennedy JL, Gelernter J. NOTCH4 gene haplotype is associated with schizophrenia in African Americans. Biol Psychiatry. 2004 Jan 15; 55(2):112-7.
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    153. Southwick SM, Charney DS. Responses to trauma: normal reactions or pathological symptoms. Psychiatry. 2004; 67(2):170-3.
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    154. Charney DS. Discovering the neural basis of human social anxiety: a diagnostic and therapeutic imperative. Am J Psychiatry. 2004 Jan; 161(1):1-2.
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    155. Zarate CA, Payne JL, Quiroz J, Sporn J, Denicoff KK, Luckenbaugh D, Charney DS, Manji HK. An open-label trial of riluzole in patients with treatment-resistant major depression. Am J Psychiatry. 2004 Jan; 161(1):171-4.
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    156. Ernst M, Nelson EE, McClure EB, Monk CS, Munson S, Eshel N, Zarahn E, Leibenluft E, Zametkin A, Towbin K, Blair J, Charney D, Pine DS. Choice selection and reward anticipation: an fMRI study. Neuropsychologia. 2004; 42(12):1585-97.
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    157. Bonne O, Charney DS. Neuropathology of stress: prospects and caveats. Psychiatry. 2004; 67(4):407-11.
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    158. Friedman MJ, Hamblen JL, Foa EB, Charney DS. Fighting the psychological war on terrorism. Psychiatry. 2004; 67(2):123-36.
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    159. Monk CS, Grillon C, Baas JM, McClure EB, Nelson EE, Zarahn E, Charney DS, Ernst M, Pine DS. A neuroimaging method for the study of threat in adolescents. Dev Psychobiol. 2003 Dec; 43(4):359-66.
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    160. Leibenluft E, Blair RJ, Charney DS, Pine DS. Irritability in pediatric mania and other childhood psychopathology. Ann N Y Acad Sci. 2003 Dec; 1008:201-18.
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    161. Blumberg HP, Kaufman J, Martin A, Whiteman R, Zhang JH, Gore JC, Charney DS, Krystal JH, Peterson BS. Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder. Arch Gen Psychiatry. 2003 Dec; 60(12):1201-8.
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    162. Coyle JT, Pine DS, Charney DS, Lewis L, Nemeroff CB, Carlson GA, Joshi PT, Reiss D, Todd RD, Hellander M. Depression and bipolar support alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in children and adolescents. J Am Acad Child Adolesc Psychiatry. 2003 Dec; 42(12):1494-503.
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    163. Zarate CA, Du J, Quiroz J, Gray NA, Denicoff KD, Singh J, Charney DS, Manji HK. Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system. Ann N Y Acad Sci. 2003 Nov; 1003:273-91.
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    164. Krystal JH, Petrakis IL, Limoncelli D, Webb E, Gueorgueva R, D'Souza DC, Boutros NN, Trevisan L, Charney DS. Altered NMDA glutamate receptor antagonist response in recovering ethanol-dependent patients. Neuropsychopharmacology. 2003 Nov; 28(11):2020-8.
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    165. Kugaya A, Sanacora G, Verhoeff NP, Fujita M, Mason GF, Seneca NM, Bozkurt A, Khan SA, Anand A, Degen K, Charney DS, Zoghbi SS, Baldwin RM, Seibyl JP, Innis RB. Cerebral benzodiazepine receptors in depressed patients measured with [123I]iomazenil SPECT. Biol Psychiatry. 2003 Oct 15; 54(8):792-9.
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    166. Vermetten E, Vythilingam M, Southwick SM, Charney DS, Bremner JD. Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder. Biol Psychiatry. 2003 Oct 1; 54(7):693-702.
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    167. Bremner JD, Vythilingam M, Anderson G, Vermetten E, McGlashan T, Heninger G, Rasmusson A, Southwick SM, Charney DS. Assessment of the hypothalamic-pituitary-adrenal axis over a 24-hour diurnal period and in response to neuroendocrine challenges in women with and without childhood sexual abuse and posttraumatic stress disorder. Biol Psychiatry. 2003 Oct 1; 54(7):710-8.
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    168. Monk CS, McClure EB, Nelson EE, Zarahn E, Bilder RM, Leibenluft E, Charney DS, Ernst M, Pine DS. Adolescent immaturity in attention-related brain engagement to emotional facial expressions. Neuroimage. 2003 Sep; 20(1):420-8.
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    169. Charney DS. The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment. Dialogues Clin Neurosci. 2003 Sep; 5(3):207-21.
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    170. Evans DL, Charney DS. Mood disorders and medical illness: a major public health problem. Biol Psychiatry. 2003 Aug 1; 54(3):177-80.
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    171. Bremner JD, Vythilingam M, Vermetten E, Adil J, Khan S, Nazeer A, Afzal N, McGlashan T, Elzinga B, Anderson GM, Heninger G, Southwick SM, Charney DS. Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse. Psychoneuroendocrinology. 2003 Aug; 28(6):733-50.
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    172. Charney DS, Reynolds CF, Lewis L, Lebowitz BD, Sunderland T, Alexopoulos GS, Blazer DG, Katz IR, Meyers BS, Arean PA, Borson S, Brown C, Bruce ML, Callahan CM, Charlson ME, Conwell Y, Cuthbert BN, Devanand DP, Gibson MJ, Gottlieb GL, Krishnan KR, Laden SK, Lyketsos CG, Mulsant BH, Niederehe G, Olin JT, Oslin DW, Pearson J, Persky T, Pollock BG, Raetzman S, Reynolds M, Salzman C, Schulz R, Schwenk TL, Scolnick E, Unutzer J, Weissman MM, Young RC. Depression and Bipolar Support Alliance consensus statement on the unmet needs in diagnosis and treatment of mood disorders in late life. Arch Gen Psychiatry. 2003 Jul; 60(7):664-72.
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    173. Blumberg HP, Martin A, Kaufman J, Leung HC, Skudlarski P, Lacadie C, Fulbright RK, Gore JC, Charney DS, Krystal JH, Peterson BS. Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI. Am J Psychiatry. 2003 Jul; 160(7):1345-7.
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    174. Bremner JD, Vythilingam M, Ng CK, Vermetten E, Nazeer A, Oren DA, Berman RM, Charney DS. Regional brain metabolic correlates of alpha-methylparatyrosine-induced depressive symptoms: implications for the neural circuitry of depression. JAMA. 2003 Jun 18; 289(23):3125-34.
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    175. Insel TR, Charney DS. Research on major depression: strategies and priorities. JAMA. 2003 Jun 18; 289(23):3167-8.
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    176. Leibenluft E, Charney DS, Pine DS. Researching the pathophysiology of pediatric bipolar disorder. Biol Psychiatry. 2003 Jun 1; 53(11):1009-20.
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    177. Blumberg HP, Leung HC, Skudlarski P, Lacadie CM, Fredericks CA, Harris BC, Charney DS, Gore JC, Krystal JH, Peterson BS. A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices. Arch Gen Psychiatry. 2003 Jun; 60(6):601-9.
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    178. Bremner JD, Vythilingam M, Vermetten E, Southwick SM, McGlashan T, Staib LH, Soufer R, Charney DS. Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse. Biol Psychiatry. 2003 May 15; 53(10):879-89.
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    179. Friedman MJ, Foa EB, Charney DS. Toward evidence-based early interventions for acutely traumatized adults and children. Biol Psychiatry. 2003 May 1; 53(9):765-8.
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    180. Bremner JD, Vythilingam M, Vermetten E, Southwick SM, McGlashan T, Nazeer A, Khan S, Vaccarino LV, Soufer R, Garg PK, Ng CK, Staib LH, Duncan JS, Charney DS. MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder. Am J Psychiatry. 2003 May; 160(5):924-32.
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    181. Kupfer DJ, Charney DS. "Difficult-to-treat depression". Biol Psychiatry. 2003 Apr 15; 53(8):633-4.
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    182. Manji HK, Quiroz JA, Sporn J, Payne JL, Denicoff K, A Gray N, Zarate CA, Charney DS. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biol Psychiatry. 2003 Apr 15; 53(8):707-42.
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    183. Southwick SM, Axelrod SR, Wang S, Yehuda R, Morgan CA, Charney D, Rosenheck R, Mason JW. Twenty-four-hour urine cortisol in combat veterans with PTSD and comorbid borderline personality disorder. J Nerv Ment Dis. 2003 Apr; 191(4):261-2.
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    184. Leibenluft E, Charney DS, Towbin KE, Bhangoo RK, Pine DS. Defining clinical phenotypes of juvenile mania. Am J Psychiatry. 2003 Mar; 160(3):430-7.
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    185. Charney DS. Neuroanatomical circuits modulating fear and anxiety behaviors. Acta Psychiatr Scand Suppl. 2003; (417):38-50.
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    186. Vythilingam M, Heim C, Newport J, Miller AH, Anderson E, Bronen R, Brummer M, Staib L, Vermetten E, Charney DS, Nemeroff CB, Bremner JD. Childhood trauma associated with smaller hippocampal volume in women with major depression. Am J Psychiatry. 2002 Dec; 159(12):2072-80.
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    187. Gold PW, Charney DS. Diseases of the mind and brain: depression: a disease of the mind, brain, and body. Am J Psychiatry. 2002 Nov; 159(11):1826.
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    188. Pine D, Charney D. Children, stress, and sensitization: an integration of basic and clinical research on emotion? Biol Psychiatry. 2002 Oct 15; 52(8):773.
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    189. Blumberg HP, Charney DS, Krystal JH. Frontotemporal neural systems in bipolar disorder. Semin Clin Neuropsychiatry. 2002 Oct; 7(4):243-54.
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    190. Blumberg HP, Charney DS. The neuroanatomy of mood disorders. Introduction. Semin Clin Neuropsychiatry. 2002 Oct; 7(4):221-2.
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    191. Charney DS, Babich KS. Foundation for the NIMH strategic plan for mood disorders research. Biol Psychiatry. 2002 Sep 15; 52(6):455-6.
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    192. Gold PW, Drevets WC, Charney DS. New insights into the role of cortisol and the glucocorticoid receptor in severe depression. Biol Psychiatry. 2002 Sep 1; 52(5):381-5.
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    193. Lappalainen J, Kranzler HR, Malison R, Price LH, Van Dyck C, Rosenheck RA, Cramer J, Southwick S, Charney D, Krystal J, Gelernter J. A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States. Arch Gen Psychiatry. 2002 Sep; 59(9):825-31.
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    194. Stine SM, Southwick SM, Petrakis IL, Kosten TR, Charney DS, Krystal JH. Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients. Biol Psychiatry. 2002 Apr 15; 51(8):642-51.
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    195. Abi-Saab W, Seibyl JP, D'Souza DC, Karper LP, Gueorgueva R, Abi-Dargham A, Wong ML, Rajhans S, Erdos JP, Heninger GR, Charney DS, Krystal JH. Ritanserin antagonism of m-chlorophenylpiperazine effects in neuroleptic-free schizophrenics patients: support for serotonin-2 receptor modulation of schizophrenia symptoms. Psychopharmacology (Berl). 2002 Jun; 162(1):55-62.
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    196. Monk CS, Pine DS, Charney DS. A developmental and neurobiological approach to early trauma research. Semin Clin Neuropsychiatry. 2002 Apr; 7(2):137-46.
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    197. Berman RM, Sanacora G, Anand A, Roach LM, Fasula MK, Finkelstein CO, Wachen RM, Oren DA, Heninger GR, Charney DS. Monoamine depletion in unmedicated depressed subjects. Biol Psychiatry. 2002 Mar 15; 51(6):469-73.
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    198. Charney DS, Nemeroff CB, Lewis L, Laden SK, Gorman JM, Laska EM, Borenstein M, Bowden CL, Caplan A, Emslie GJ, Evans DL, Geller B, Grabowski LE, Herson J, Kalin NH, Keck PE, Kirsch I, Krishnan KR, Kupfer DJ, Makuch RW, Miller FG, Pardes H, Post R, Reynolds MM, Roberts L, Rosenbaum JF, Rosenstein DL, Rubinow DR, Rush AJ, Ryan ND, Sachs GS, Schatzberg AF, Solomon S. National Depressive and Manic-Depressive Association consensus statement on the use of placebo in clinical trials of mood disorders. Arch Gen Psychiatry. 2002 Mar; 59(3):262-70.
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    199. Oren DA, Desan PH, Boutros N, Anand A, Charney DS. Effects of light on low nocturnal bilirubin in winter depression: a preliminary report. Biol Psychiatry. 2002 Mar 1; 51(5):422-5.
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    200. Sporn J, Charney D. Monoamine and neuropeptide-related function: prospects for novel therapeutics of depression. Expert Rev Neurother. 2002 Mar; 2(2):217-32.
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    201. Mason JW, Wang S, Yehuda R, Lubin H, Johnson D, Bremner JD, Charney D, Southwick S. Marked lability in urinary cortisol levels in subgroups of combat veterans with posttraumatic stress disorder during an intensive exposure treatment program. Psychosom Med. 2002 Mar-Apr; 64(2):238-46.
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    202. Bremner JD, Vythilingam M, Vermetten E, Nazeer A, Adil J, Khan S, Staib LH, Charney DS. Reduced volume of orbitofrontal cortex in major depression. Biol Psychiatry. 2002 Feb 15; 51(4):273-9.
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    203. Krystal JH, Sanacora G, Blumberg H, Anand A, Charney DS, Marek G, Epperson CN, Goddard A, Mason GF. Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments. Mol Psychiatry. 2002; 7 Suppl 1:S71-80.
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    204. Charney DS, Grothe DR, Smith SL, Brady KT, Kaltsounis-Puckett J, Wright CW, Laird LK, Rush AJ. Overview of psychiatric disorders and the role of newer antidepressants. J Clin Psychiatry. 2002; 63 Suppl 1:3-9.
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    205. Rasmusson AM, Lipschitz DS, Wang S, Hu S, Vojvoda D, Bremner JD, Southwick SM, Charney DS. Increased pituitary and adrenal reactivity in premenopausal women with posttraumatic stress disorder. Biol Psychiatry. 2001 Dec 15; 50(12):965-77.
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    206. Ree HJ, Yang WI, Kim CW, Huh J, Lee SS, Cho EY, Ko YH, Charney D. Coexpression of Bcl-6 and CD10 in diffuse large B-cell lymphomas: significance of Bcl-6 expression patterns in identifying germinal center B-cell lymphoma. Hum Pathol. 2001 Sep; 32(9):954-62.
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    207. Messias NC, Eustace JA, Zachary AA, Tucker PC, Charney D, Racusen LC. Cohort study of the prognostic significance of acute transplant glomerulitis in acutely rejecting renal allografts. Transplantation. 2001 Aug 27; 72(4):655-60.
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    208. Leffell MS, Kraus E, Racusen LC, Ratner LE, Charney D, Zachary AA. Effect of Bw4 and Bw6 epitope mismatches on antibody production, acute and chronic rejection, and graft survival in renal allografts. Transplantation. 2001 Aug 15; 72(3):433-7.
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    209. Potenza MN, Charney DS. Pathological gambling: a current perspective. Semin Clin Neuropsychiatry. 2001 Jul; 6(3):153-4.
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    210. Goddard AW, Brouette T, Almai A, Jetty P, Woods SW, Charney D. Early coadministration of clonazepam with sertraline for panic disorder. Arch Gen Psychiatry. 2001 Jul; 58(7):681-6.
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    211. Kaufman J, Martin A, King RA, Charney D. Are child-, adolescent-, and adult-onset depression one and the same disorder? Biol Psychiatry. 2001 Jun 15; 49(12):980-1001.
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    212. Goddard AW, Mason GF, Almai A, Rothman DL, Behar KL, Petroff OA, Charney DS, Krystal JH. Reductions in occipital cortex GABA levels in panic disorder detected with 1h-magnetic resonance spectroscopy. Arch Gen Psychiatry. 2001 Jun; 58(6):556-61.
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    213. Morgan CA, Wang S, Rasmusson A, Hazlett G, Anderson G, Charney DS. Relationship among plasma cortisol, catecholamines, neuropeptide Y, and human performance during exposure to uncontrollable stress. Psychosom Med. 2001 May-Jun; 63(3):412-22.
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    214. Mason JW, Wang S, Yehuda R, Riney S, Charney DS, Southwick SM. Psychogenic lowering of urinary cortisol levels linked to increased emotional numbing and a shame-depressive syndrome in combat-related posttraumatic stress disorder. Psychosom Med. 2001 May-Jun; 63(3):387-401.
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    215. Manji HK, Drevets WC, Charney DS. The cellular neurobiology of depression. Nat Med. 2001 May; 7(5):541-7.
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    216. Krystal JH, D'Souza DC, Sanacora G, Goddard AW, Charney DS. Current perspectives on the pathophysiology of schizophrenia, depression, and anxiety disorders. Med Clin North Am. 2001 May; 85(3):559-77.
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    217. Stine SM, Grillon CG, Morgan CA, Kosten TR, Charney DS, Krystal JH. Methadone patients exhibit increased startle and cortisol response after intravenous yohimbine. Psychopharmacology (Berl). 2001 Mar; 154(3):274-81.
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    218. Jetty PV, Charney DS, Goddard AW. Neurobiology of generalized anxiety disorder. Psychiatr Clin North Am. 2001 Mar; 24(1):75-97.
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    219. Oren DA, Charney DS, Lavie R, Sinyakov M, Lubart R. Stimulation of reactive oxygen species production by an antidepressant visible light source. Biol Psychiatry. 2001 Mar 1; 49(5):464-7.
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    220. Frank DK, Charney D, Kashani A. Plasma cell variant of Castleman's disease occurring concurrently with Hodgkin's disease in the neck. Head Neck. 2001 Feb; 23(2):166-9.
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    221. Woods SW, Stolar M, Sernyak MJ, Charney DS. Consistency of atypical antipsychotic superiority to placebo in recent clinical trials. Biol Psychiatry. 2001 Jan 1; 49(1):64-70.
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    222. Bremner JD, Soufer R, McCarthy G, Delaney R, Staib LH, Duncan JS, Charney DS. Gender differences in cognitive and neural correlates of remembrance of emotional words. Psychopharmacol Bull. 2001; 35(3):55-78.
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    223. Kaufman J, Charney D. Effects of early stress on brain structure and function: implications for understanding the relationship between child maltreatment and depression. Dev Psychopathol. 2001; 13(3):451-71.
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    224. Cramer J, Rosenheck R, Xu W, Henderson W, Thomas J, Charney D. Detecting improvement in quality of life and symptomatology in schizophrenia. Schizophr Bull. 2001; 27(2):227-34.
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    225. van Dyck CH, Soares JC, Tan PZ, Staley JK, Baldwin RM, Amici LA, Fu X, Garg PK, Seibyl JP, Charney DS, Innis RB. Equilibrium modeling of 5-HT(2A) receptors with [18F]deuteroaltanserin and PET: feasibility of a constant infusion paradigm. Nucl Med Biol. 2000 Nov; 27(8):715-22.
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    226. Vythilingam M, Anderson GM, Owens MJ, Halaszynski TM, Bremner JD, Carpenter LL, Heninger GR, Nemeroff CB, Charney DS. Cerebrospinal fluid corticotropin-releasing hormone in healthy humans: effects of yohimbine and naloxone. J Clin Endocrinol Metab. 2000 Nov; 85(11):4138-45.
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    227. Fujita M, Charney DS, Innis RB. Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations. Biol Psychiatry. 2000 Oct 15; 48(8):801-12.
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    228. Kaufman J, Plotsky PM, Nemeroff CB, Charney DS. Effects of early adverse experiences on brain structure and function: clinical implications. Biol Psychiatry. 2000 Oct 15; 48(8):778-90.
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    229. Charney DS. Bipolar disorder: can studies of natural history help us define clinically and neurobiologically relevant subtypes? Biol Psychiatry. 2000 Sep 15; 48(6):427.
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    230. Rosenheck R, Cramer J, Jurgis G, Perlick D, Xu W, Thomas J, Henderson W, Charney D. Clinical and psychopharmacologic factors influencing family burden in refractory schizophrenia. The Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. J Clin Psychiatry. 2000 Sep; 61(9):671-6.
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    231. Vythilingam M, Anderson ER, Goddard A, Woods SW, Staib LH, Charney DS, Bremner JD. Temporal lobe volume in panic disorder--a quantitative magnetic resonance imaging study. Psychiatry Res. 2000 Aug 28; 99(2):75-82.
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    232. Varrone A, Fujita M, Verhoeff NP, Zoghbi SS, Baldwin RM, Rajeevan N, Charney DS, Seibyl JP, Innis RB. Test-retest reproducibility of extrastriatal dopamine D2 receptor imaging with [123I]epidepride SPECT in humans. J Nucl Med. 2000 Aug; 41(8):1343-51.
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    233. Oren DA, Berman RM, Anand A, Charney DS. No effect of light on basal glucagon levels in winter seasonal depressives and comparison subjects. Psychiatry Res. 2000 Jul 17; 94(3):263-6.
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    234. Bremner JD, Innis RB, Southwick SM, Staib L, Zoghbi S, Charney DS. Decreased benzodiazepine receptor binding in prefrontal cortex in combat-related posttraumatic stress disorder. Am J Psychiatry. 2000 Jul; 157(7):1120-6.
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    235. Anand A, Verhoeff P, Seneca N, Zoghbi SS, Seibyl JP, Charney DS, Innis RB. Brain SPECT imaging of amphetamine-induced dopamine release in euthymic bipolar disorder patients. Am J Psychiatry. 2000 Jul; 157(7):1108-14.
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    236. Desan PH, Oren DA, Malison R, Price LH, Rosenbaum J, Smoller J, Charney DS, Gelernter J. Genetic polymorphism at the CLOCK gene locus and major depression. Am J Med Genet. 2000 Jun 12; 96(3):418-21.
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    237. Ripple MG, Charney D, Nadasdy T. Cholesterol embolization in renal allografts. Transplantation. 2000 May 27; 69(10):2221-5.
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    238. Morgan CA, Wang S, Mason J, Southwick SM, Fox P, Hazlett G, Charney DS, Greenfield G. Hormone profiles in humans experiencing military survival training. Biol Psychiatry. 2000 May 15; 47(10):891-901.
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    239. Morgan CA, Wang S, Southwick SM, Rasmusson A, Hazlett G, Hauger RL, Charney DS. Plasma neuropeptide-Y concentrations in humans exposed to military survival training. Biol Psychiatry. 2000 May 15; 47(10):902-9.
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    240. Rosenheck R, Chang S, Choe Y, Cramer J, Xu W, Thomas J, Henderson W, Charney D. Medication continuation and compliance: a comparison of patients treated with clozapine and haloperidol. J Clin Psychiatry. 2000 May; 61(5):382-6.
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    241. Charney DS. The use of placebos in randomized clinical trials of mood disorders: well justified, but improvements in design are indicated. Biol Psychiatry. 2000 Apr 15; 47(8):687-8.
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    242. Hoffman RE, Boutros NN, Hu S, Berman RM, Krystal JH, Charney DS. Transcranial magnetic stimulation and auditory hallucinations in schizophrenia. Lancet. 2000 Mar 25; 355(9209):1073-5.
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    243. Rasmusson AM, Hauger RL, Morgan CA, Bremner JD, Charney DS, Southwick SM. Low baseline and yohimbine-stimulated plasma neuropeptide Y (NPY) levels in combat-related PTSD. Biol Psychiatry. 2000 Mar 15; 47(6):526-39.
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    244. D'Souza DC, Gil R, Cassello K, Morrissey K, Abi-Saab D, White J, Sturwold R, Bennett A, Karper LP, Zuzarte E, Charney DS, Krystal JH. IV glycine and oral D-cycloserine effects on plasma and CSF amino acids in healthy humans. Biol Psychiatry. 2000 Mar 1; 47(5):450-62.
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    245. Anand A, Charney DS, Oren DA, Berman RM, Hu XS, Cappiello A, Krystal JH. Attenuation of the neuropsychiatric effects of ketamine with lamotrigine: support for hyperglutamatergic effects of N-methyl-D-aspartate receptor antagonists. Arch Gen Psychiatry. 2000 Mar; 57(3):270-6.
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    246. Berman RM, Cappiello A, Anand A, Oren DA, Heninger GR, Charney DS, Krystal JH. Antidepressant effects of ketamine in depressed patients. Biol Psychiatry. 2000 Feb 15; 47(4):351-4.
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    247. Berman RM, Narasimhan M, Sanacora G, Miano AP, Hoffman RE, Hu XS, Charney DS, Boutros NN. A randomized clinical trial of repetitive transcranial magnetic stimulation in the treatment of major depression. Biol Psychiatry. 2000 Feb 15; 47(4):332-7.
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    248. van Dyck CH, Tan PZ, Baldwin RM, Amici LA, Garg PK, Ng CK, Soufer R, Charney DS, Innis RB. PET quantification of 5-HT2A receptors in the human brain: a constant infusion paradigm with [18F]altanserin. J Nucl Med. 2000 Feb; 41(2):234-41.
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    249. Krystal JH, Bennett A, Abi-Saab D, Belger A, Karper LP, D'Souza DC, Lipschitz D, Abi-Dargham A, Charney DS. Dissociation of ketamine effects on rule acquisition and rule implementation: possible relevance to NMDA receptor contributions to executive cognitive functions. Biol Psychiatry. 2000 Jan 15; 47(2):137-43.
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    250. Bremner JD, Innis RB, White T, Fujita M, Silbersweig D, Goddard AW, Staib L, Stern E, Cappiello A, Woods S, Baldwin R, Charney DS. SPECT [I-123]iomazenil measurement of the benzodiazepine receptor in panic disorder. Biol Psychiatry. 2000 Jan 15; 47(2):96-106.
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    251. Bremner JD, Narayan M, Anderson ER, Staib LH, Miller HL, Charney DS. Hippocampal volume reduction in major depression. Am J Psychiatry. 2000 Jan; 157(1):115-8.
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    252. Ovuworie C, Volmar K, Charney D, Kravet S, Racusen L. Rapidly progressive renal failure with nephrotic syndrome in a patient with type 2 diabetes mellitus: the differential of fibrillary deposits. Am J Kidney Dis. 2000 Jan; 35(1):173-7.
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    253. Bremner JD, Horti A, Staib LH, Zea-Ponce Y, Soufer R, Charney DS, Baldwin R. Kinetic modeling of benzodiazepine receptor binding with PET and high specific activity [(11)C]Iomazenil in healthy human subjects. Synapse. 2000 Jan; 35(1):68-77.
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    254. Anand A, Charney DS. Norepinephrine dysfunction in depression. J Clin Psychiatry. 2000; 61 Suppl 10:16-24.
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    255. Kaufman J, Charney D. Comorbidity of mood and anxiety disorders. Depress Anxiety. 2000; 12 Suppl 1:69-76.
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    256. Cramer JA, Rosenheck R, Xu W, Thomas J, Henderson W, Charney DS. Quality of life in schizophrenia: a comparison of instruments. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Schizophr Bull. 2000; 26(3):659-66.
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    257. Martin A, Kaufman J, Charney D. Pharmacotherapy of early-onset depression. Update and new directions. Child Adolesc Psychiatr Clin N Am. 2000 Jan; 9(1):135-57.
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    258. Fujita M, Seibyl JP, Verhoeff NP, Ichise M, Baldwin RM, Zoghbi SS, Burger C, Staley JK, Rajeevan N, Charney DS, Innis RB. Kinetic and equilibrium analyses of [(123)I]epidepride binding to striatal and extrastriatal dopamine D(2) receptors. Synapse. 1999 Dec 15; 34(4):290-304.
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    259. Ichise M, Fujita M, Seibyl JP, Verhoeff NP, Baldwin RM, Zoghbi SS, Rajeevan N, Charney DS, Innis RB. Graphical analysis and simplified quantification of striatal and extrastriatal dopamine D2 receptor binding with [123I]epidepride SPECT. J Nucl Med. 1999 Nov; 40(11):1902-12.
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    260. Bremner JD, Narayan M, Staib LH, Southwick SM, McGlashan T, Charney DS. Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder. Am J Psychiatry. 1999 Nov; 156(11):1787-95.
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    261. Sanacora G, Mason GF, Rothman DL, Behar KL, Hyder F, Petroff OA, Berman RM, Charney DS, Krystal JH. Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy. Arch Gen Psychiatry. 1999 Nov; 56(11):1043-7.
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    262. Southwick SM, Bremner JD, Rasmusson A, Morgan CA, Arnsten A, Charney DS. Role of norepinephrine in the pathophysiology and treatment of posttraumatic stress disorder. Biol Psychiatry. 1999 Nov 1; 46(9):1192-204.
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    263. D'Souza DC, Berman RM, Krystal JH, Charney DS. Symptom provocation studies in psychiatric disorders: scientific value, risks, and future. Biol Psychiatry. 1999 Oct 15; 46(8):1060-80.
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    264. Verhoeff NP, Soares JC, D'Souza CD, Gil R, Degen K, Abi-Dargham A, Zoghbi SS, Fujita M, Rajeevan N, Seibyl JP, Krystal JH, van Dyck CH, Charney DS, Innis RB. [123I]Iomazenil SPECT benzodiazepine receptor imaging in schizophrenia. Psychiatry Res. 1999 Oct 11; 91(3):163-73.
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    265. Chambers RA, Bremner JD, Moghaddam B, Southwick SM, Charney DS, Krystal JH. Glutamate and post-traumatic stress disorder: toward a psychobiology of dissociation. Semin Clin Neuropsychiatry. 1999 Oct; 4(4):274-81.
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    266. Southwick SM, Paige S, Morgan CA, Bremner JD, Krystal JH, Charney DS. Neurotransmitter alterations in PTSD: catecholamines and serotonin. Semin Clin Neuropsychiatry. 1999 Oct; 4(4):242-8.
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    267. Krystal JH, D'Souza DC, Petrakis IL, Belger A, Berman RM, Charney DS, Abi-Saab W, Madonick S. NMDA agonists and antagonists as probes of glutamatergic dysfunction and pharmacotherapies in neuropsychiatric disorders. Harv Rev Psychiatry. 1999 Sep-Oct; 7(3):125-43.
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    268. Bremner JD, Baldwin R, Horti A, Staib LH, Ng CK, Tan PZ, Zea-Ponce Y, Zoghbi S, Seibyl JP, Soufer R, Charney DS, Innis RB. Quantitation of benzodiazepine receptor binding with PET [11C]iomazenil and SPECT [123I]iomazenil: preliminary results of a direct comparison in healthy human subjects. Psychiatry Res. 1999 Aug 31; 91(2):79-91.
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    269. Charney DS. The National Bioethics Advisory Commission report: the response of the psychiatric research community is critical to restoring public trust. Arch Gen Psychiatry. 1999 Aug; 56(8):699-700.
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    270. Southwick SM, Morgan CA, Charney DS, High JR. Yohimbine use in a natural setting: effects on posttraumatic stress disorder. Biol Psychiatry. 1999 Aug 1; 46(3):442-4.
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    271. Tan PZ, Baldwin RM, Van Dyck CH, Al-Tikriti M, Roth B, Khan N, Charney DS, Innis RB. Characterization of radioactive metabolites of 5-HT2A receptor PET ligand [18F]altanserin in human and rodent. Nucl Med Biol. 1999 Aug; 26(6):601-8.
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    272. Delgado PL, Miller HL, Salomon RM, Licinio J, Krystal JH, Moreno FA, Heninger GR, Charney DS. Tryptophan-depletion challenge in depressed patients treated with desipramine or fluoxetine: implications for the role of serotonin in the mechanism of antidepressant action. Biol Psychiatry. 1999 Jul 15; 46(2):212-20.
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    273. Hoffman RE, Boutros NN, Berman RM, Roessler E, Belger A, Krystal JH, Charney DS. Transcranial magnetic stimulation of left temporoparietal cortex in three patients reporting hallucinated "voices". Biol Psychiatry. 1999 Jul 1; 46(1):130-2.
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    274. Krystal JH, D'Souza DC, Karper LP, Bennett A, Abi-Dargham A, Abi-Saab D, Cassello K, Bowers MB, Vegso S, Heninger GR, Charney DS. Interactive effects of subanesthetic ketamine and haloperidol in healthy humans. Psychopharmacology (Berl). 1999 Jul; 145(2):193-204.
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    275. Charney DS, Innis RB, Nestler EJ, Davis KL, Nemeroff CB, Weinberger DR. Increasing public trust and confidence in psychiatric research. Biol Psychiatry. 1999 Jul 1; 46(1):1-2.
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    276. Behar KL, Rothman DL, Petersen KF, Hooten M, Delaney R, Petroff OA, Shulman GI, Navarro V, Petrakis IL, Charney DS, Krystal JH. Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients. Am J Psychiatry. 1999 Jun; 156(6):952-4.
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    277. Abi-Dargham A, Laruelle M, Krystal J, D'Souza C, Zoghbi S, Baldwin RM, Seibyl J, Mawlawi O, de Erasquin G, Charney D, Innis RB. No evidence of altered in vivo benzodiazepine receptor binding in schizophrenia. Neuropsychopharmacology. 1999 Jun; 20(6):650-61.
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    278. Rosenheck R, Cramer J, Allan E, Erdos J, Frisman LK, Xu W, Thomas J, Henderson W, Charney D. Cost-effectiveness of clozapine in patients with high and low levels of hospital use. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Arch Gen Psychiatry. 1999 Jun; 56(6):565-72.
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    279. Kaufman J, Charney DS. Neurobiological correlates of child abuse. Biol Psychiatry. 1999 May 15; 45(10):1235-6.
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    280. Duman RS, Charney DS. Cell atrophy and loss in major depression. Biol Psychiatry. 1999 May 1; 45(9):1083-4.
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    281. Berman RM, Anand A, Cappiello A, Miller HL, Hu XS, Oren DA, Charney DS. The use of pindolol with fluoxetine in the treatment of major depression: final results from a double-blind, placebo-controlled trial. Biol Psychiatry. 1999 May 1; 45(9):1170-7.
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    282. Tan PZ, Baldwin RM, Soufer R, Garg PK, Charney DS, Innis RB. A complete remote-control system for reliable preparation of [18F]altanserin. Appl Radiat Isot. 1999 May; 50(5):923-7.
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    283. Cicchetti DV, Rosenheck R, Showalter D, Charney D, Cramer J. Interrater reliability levels of multiple clinical examiners in the evaluation of a schizophrenic patient: quality of life, level of functioning, and neuropsychological symptomatology. Clin Neuropsychol. 1999 May; 13(2):157-70.
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    284. Berman RM, Narasimhan M, Miller HL, Anand A, Cappiello A, Oren DA, Heninger GR, Charney DS. Transient depressive relapse induced by catecholamine depletion: potential phenotypic vulnerability marker? Arch Gen Psychiatry. 1999 May; 56(5):395-403.
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    285. Anand A, Darnell A, Miller HL, Berman RM, Cappiello A, Oren DA, Woods SW, Charney DS. Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder. Biol Psychiatry. 1999 Apr 15; 45(8):972-8.
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    286. Bremner JD, Staib LH, Kaloupek D, Southwick SM, Soufer R, Charney DS. Neural correlates of exposure to traumatic pictures and sound in Vietnam combat veterans with and without posttraumatic stress disorder: a positron emission tomography study. Biol Psychiatry. 1999 Apr 1; 45(7):806-16.
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    287. Goddard AW, Woods SW, Money R, Pande AC, Charney DS, Goodman WK, Heninger GR, Price LH. Effects of the CCK(B) antagonist CI-988 on responses to mCPP in generalized anxiety disorder. Psychiatry Res. 1999 Mar 22; 85(3):225-40.
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    288. Fujita M, Woods SW, Verhoeff NP, Abi-Dargham A, Baldwin RM, Zoghbi SS, Soares JC, Jatlow PA, Krystal JH, Rajeevan N, Charney DS, Seibyl JP, Innis RB. Changes of benzodiazepine receptors during chronic benzodiazepine administration in humans. Eur J Pharmacol. 1999 Mar 5; 368(2-3):161-72.
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    289. Gelernter J, Southwick S, Goodson S, Morgan A, Nagy L, Charney DS. No association between D2 dopamine receptor (DRD2) "A" system alleles, or DRD2 haplotypes, and posttraumatic stress disorder. Biol Psychiatry. 1999 Mar 1; 45(5):620-5.
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    290. Johnson DR, Lubin H, Rosenheck R, Fontana A, Charney D, Southwick S. Comparison of outcome between homogeneous and heterogeneous treatment environments in combat-related posttraumatic stress disorder. J Nerv Ment Dis. 1999 Feb; 187(2):88-95.
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    291. Rosenheck R, Charney D, Cramer J. Clozapine and hospitalization. Psychiatr Serv. 1999 Jan; 50(1):114-6.
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    292. Rosenheck R, Dunn L, Peszke M, Cramer J, Xu W, Thomas J, Charney D. Impact of clozapine on negative symptoms and on the deficit syndrome in refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Am J Psychiatry. 1999 Jan; 156(1):88-93.
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    293. Berman RM, Charney DS. Models of antidepressant action. J Clin Psychiatry. 1999; 60 Suppl 14:16-20; discussion 31-5.
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    294. Rosenheck R, Evans D, Herz L, Cramer J, Xu W, Thomas J, Henderson W, Charney D. How long to wait for a response to clozapine: a comparison of time course of response to clozapine and conventional antipsychotic medication in refractory schizophrenia. Schizophr Bull. 1999; 25(4):709-19.
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    295. Rosenheck R, Cramer J, Xu W, Grabowski J, Douyon R, Thomas J, Henderson W, Charney D. Multiple outcome assessment in a study of the cost-effectiveness of clozapine in the treatment of refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Health Serv Res. 1998 Dec; 33(5 Pt 1):1237-61.
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    296. Malison RT, Price LH, Berman R, van Dyck CH, Pelton GH, Carpenter L, Sanacora G, Owens MJ, Nemeroff CB, Rajeevan N, Baldwin RM, Seibyl JP, Innis RB, Charney DS. Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography. Biol Psychiatry. 1998 Dec 1; 44(11):1090-8.
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    297. Abi-Dargham A, Krystal JH, Anjilvel S, Scanley BE, Zoghbi S, Baldwin RM, Rajeevan N, Ellis S, Petrakis IL, Seibyl JP, Charney DS, Laruelle M, Innis RB. Alterations of benzodiazepine receptors in type II alcoholic subjects measured with SPECT and [123I]iomazenil. Am J Psychiatry. 1998 Nov; 155(11):1550-5.
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    298. Rosenheck R, Lawson W, Crayton J, Cramer J, Xu W, Thomas J, Stolar M, Charney D. Predictors of differential response to clozapine and haloperidol. Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Biol Psychiatry. 1998 Sep 15; 44(6):475-82.
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    299. Cappiello A, McDougle CJ, Delgado PL, Malison RT, Jatlow P, Charney DS, Heninger GR, Price LH. Lithium and desipramine versus desipramine alone in the treatment of severe major depression: a preliminary study. Int Clin Psychopharmacol. 1998 Sep; 13(5):191-8.
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    300. Seibyl JP, Marek K, Sheff K, Zoghbi S, Baldwin RM, Charney DS, van Dyck CH, Innis RB. Iodine-123-beta-CIT and iodine-123-FPCIT SPECT measurement of dopamine transporters in healthy subjects and Parkinson's patients. J Nucl Med. 1998 Sep; 39(9):1500-8.
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    301. Rasmusson AM, Southwick SM, Hauger RL, Charney DS. Plasma neuropeptide Y (NPY) increases in humans in response to the alpha 2 antagonist yohimbine. Neuropsychopharmacology. 1998 Jul; 19(1):95-8.
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    302. Rosenheck R, Tekell J, Peters J, Cramer J, Fontana A, Xu W, Thomas J, Henderson W, Charney D. Does participation in psychosocial treatment augment the benefit of clozapine? Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. Arch Gen Psychiatry. 1998 Jul; 55(7):618-25.
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    303. Abi-Dargham A, Gil R, Krystal J, Baldwin RM, Seibyl JP, Bowers M, van Dyck CH, Charney DS, Innis RB, Laruelle M. Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort. Am J Psychiatry. 1998 Jun; 155(6):761-7.
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    304. Sernyak MJ, Glazer WM, Heninger GR, Charney DS, Woods SW, Petrakis IL, Krystal JH, Price LH. Naltrexone augmentation of neuroleptics in schizophrenia. J Clin Psychopharmacol. 1998 Jun; 18(3):248-51.
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    305. Krystal JH, Petrakis IL, Webb E, Cooney NL, Karper LP, Namanworth S, Stetson P, Trevisan LA, Charney DS. Dose-related ethanol-like effects of the NMDA antagonist, ketamine, in recently detoxified alcoholics. Arch Gen Psychiatry. 1998 Apr; 55(4):354-60.
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    306. Krystal JH, Karper LP, Bennett A, D'Souza DC, Abi-Dargham A, Morrissey K, Abi-Saab D, Bremner JD, Bowers MB, Suckow RF, Stetson P, Heninger GR, Charney DS. Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans. Psychopharmacology (Berl). 1998 Feb; 135(3):213-29.
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    307. Bremner JD, Krystal JH, Putnam FW, Southwick SM, Marmar C, Charney DS, Mazure CM. Measurement of dissociative states with the Clinician-Administered Dissociative States Scale (CADSS). J Trauma Stress. 1998 Jan; 11(1):125-36.
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    308. Goddard AW, Charney DS. SSRIs in the treatment of panic disorder. Depress Anxiety. 1998; 8 Suppl 1:114-20.
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    309. Charney DS. Monoamine dysfunction and the pathophysiology and treatment of depression. J Clin Psychiatry. 1998; 59 Suppl 14:11-4.
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    310. Gelernter J, Van Dyck C, van Kammen DP, Malison R, Price LH, Cubells JF, Berman R, Charney DS, Heninger G. Ciliary neurotrophic factor null allele frequencies in schizophrenia, affective disorders, and Alzheimer's disease. Am J Med Genet. 1997 Sep 19; 74(5):497-500.
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    311. Rosenheck R, Cramer J, Xu W, Thomas J, Henderson W, Frisman L, Fye C, Charney D. A comparison of clozapine and haloperidol in hospitalized patients with refractory schizophrenia. Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia. N Engl J Med. 1997 Sep 18; 337(12):809-15.
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    312. Seibyl JP, Marek K, Sheff K, Baldwin RM, Zoghbi S, Zea-Ponce Y, Charney DS, van Dyck CH, Hoffer PB, Innis RB. Test/retest reproducibility of iodine-123-betaCIT SPECT brain measurement of dopamine transporters in Parkinson's patients. J Nucl Med. 1997 Sep; 38(9):1453-9.
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    313. Laruelle M, D'Souza CD, Baldwin RM, Abi-Dargham A, Kanes SJ, Fingado CL, Seibyl JP, Zoghbi SS, Bowers MB, Jatlow P, Charney DS, Innis RB. Imaging D2 receptor occupancy by endogenous dopamine in humans. Neuropsychopharmacology. 1997 Sep; 17(3):162-74.
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    314. Stine SM, Krystal JH, Petrakis IL, Jatlow PI, Heninger GR, Kosten TR, Charney DS. Effect of alpha-methyl-para-tyrosine on response to cocaine challenge. Biol Psychiatry. 1997 Aug 1; 42(3):181-90.
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    315. Southwick SM, Krystal JH, Bremner JD, Morgan CA, Nicolaou AL, Nagy LM, Johnson DR, Heninger GR, Charney DS. Noradrenergic and serotonergic function in posttraumatic stress disorder. Arch Gen Psychiatry. 1997 Aug; 54(8):749-58.
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    316. Southwick SM, Morgan CA, Bremner AD, Grillon CG, Krystal JH, Nagy LM, Charney DS. Noradrenergic alterations in posttraumatic stress disorder. Ann N Y Acad Sci. 1997 Jun 21; 821:125-41.
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    317. Rasmusson AM, Charney DS. Animal models of relevance to PTSD. Ann N Y Acad Sci. 1997 Jun 21; 821:332-51.
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    318. Krystal JH, Webb E, Grillon C, Cooney N, Casal L, Morgan CA, Southwick SM, Davis M, Charney DS. Evidence of acoustic startle hyperreflexia in recently detoxified early onset male alcoholics: modulation by yohimbine and m-chlorophenylpiperazine (mCPP). Psychopharmacology (Berl). 1997 Jun; 131(3):207-15.
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    319. Bremner JD, Licinio J, Darnell A, Krystal JH, Owens MJ, Southwick SM, Nemeroff CB, Charney DS. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. Am J Psychiatry. 1997 May; 154(5):624-9.
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    320. Barr LC, Heninger GR, Goodman W, Charney DS, Price LH. Effects of fluoxetine administration on mood response to tryptophan depletion in healthy subjects. Biol Psychiatry. 1997 May 1; 41(9):949-54.
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    321. Bremner JD, Innis RB, Salomon RM, Staib LH, Ng CK, Miller HL, Bronen RA, Krystal JH, Duncan J, Rich D, Price LH, Malison R, Dey H, Soufer R, Charney DS. Positron emission tomography measurement of cerebral metabolic correlates of tryptophan depletion-induced depressive relapse. Arch Gen Psychiatry. 1997 Apr; 54(4):364-74.
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    322. Johnson DR, Lubin H, Rosenheck R, Fontana A, Southwick S, Charney D. The impact of the homecoming reception on the development of posttraumatic stress disorder. The West Haven Homecoming Stress Scale (WHHSS). J Trauma Stress. 1997 Apr; 10(2):259-77.
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    323. Abi-Dargham A, Zea-Ponce Y, Terriere D, al-Tikriti M, Baldwin RM, Hoffer P, Charney D, Leysen JE, Laruelle M, Mertens J, Innis RB. Preclinical evaluation of [123I]R93274 as a SPECT radiotracer for imaging 5-HT2A receptors. Eur J Pharmacol. 1997 Mar 5; 321(3):285-93.
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    324. Bremner JD, Innis RB, Ng CK, Staib LH, Salomon RM, Bronen RA, Duncan J, Southwick SM, Krystal JH, Rich D, Zubal G, Dey H, Soufer R, Charney DS. Positron emission tomography measurement of cerebral metabolic correlates of yohimbine administration in combat-related posttraumatic stress disorder. Arch Gen Psychiatry. 1997 Mar; 54(3):246-54.
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    325. Southwick SM, Morgan CA, Nicolaou AL, Charney DS. Consistency of memory for combat-related traumatic events in veterans of Operation Desert Storm. Am J Psychiatry. 1997 Feb; 154(2):173-7.
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    326. Wang S, Mason J, Charney D, Yehuda R, Riney S, Southwick S. Relationships between hormonal profile and novelty seeking in combat-related posttraumatic stress disorder. Biol Psychiatry. 1997 Jan 15; 41(2):145-51.
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    327. Goddard AW, Charney DS. Toward an integrated neurobiology of panic disorder. J Clin Psychiatry. 1997; 58 Suppl 2:4-11; discussion 11-2.
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    328. Berman RM, Darnell AM, Miller HL, Anand A, Charney DS. Effect of pindolol in hastening response to fluoxetine in the treatment of major depression: a double-blind, placebo-controlled trial. Am J Psychiatry. 1997 Jan; 154(1):37-43.
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    329. Salomon RM, Miller HL, Krystal JH, Heninger GR, Charney DS. Lack of behavioral effects of monoamine depletion in healthy subjects. Biol Psychiatry. 1997 Jan 1; 41(1):58-64.
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    330. Laruelle M, Iyer RN, al-Tikriti MS, Zea-Ponce Y, Malison R, Zoghbi SS, Baldwin RM, Kung HF, Charney DS, Hoffer PB, Innis RB, Bradberry CW. Microdialysis and SPECT measurements of amphetamine-induced dopamine release in nonhuman primates. Synapse. 1997 Jan; 25(1):1-14.
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    331. Bremner JD, Randall P, Vermetten E, Staib L, Bronen RA, Mazure C, Capelli S, McCarthy G, Innis RB, Charney DS. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report. Biol Psychiatry. 1997 Jan 1; 41(1):23-32.
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    332. Abi-Dargham A, Laruelle M, Aghajanian GK, Charney D, Krystal J. The role of serotonin in the pathophysiology and treatment of schizophrenia. J Neuropsychiatry Clin Neurosci. 1997; 9(1):1-17.
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    333. Berman RM, Narasimhan M, Charney DS. Treatment-refractory depression: definitions and characteristics. Depress Anxiety. 1997; 5(4):154-64.
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    334. Cappiello A, Malison RT, McDougle CJ, Vegso SJ, Charney DS, Heninger GR, Price LH. Seasonal variation in neuroendocrine and mood responses to i.v. L-tryptophan in depressed patients and healthy subjects. Neuropsychopharmacology. 1996 Nov; 15(5):475-83.
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    335. Grillon C, Morgan CA, Southwick SM, Davis M, Charney DS. Baseline startle amplitude and prepulse inhibition in Vietnam veterans with posttraumatic stress disorder. Psychiatry Res. 1996 Oct 16; 64(3):169-78.
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    336. Grillon C, Southwick SM, Charney DS. The psychobiological basis of posttraumatic stress disorder. Mol Psychiatry. 1996 Sep; 1(4):278-97.
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    337. Laruelle M, Abi-Dargham A, van Dyck CH, Gil R, D'Souza CD, Erdos J, McCance E, Rosenblatt W, Fingado C, Zoghbi SS, Baldwin RM, Seibyl JP, Krystal JH, Charney DS, Innis RB. Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc Natl Acad Sci U S A. 1996 Aug 20; 93(17):9235-40.
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    338. Abi-Dargham A, Gandelman MS, DeErausquin GA, Zea-Ponce Y, Zoghbi SS, Baldwin RM, Laruelle M, Charney DS, Hoffer PB, Neumeyer JL, Innis RB. SPECT imaging of dopamine transporters in human brain with iodine-123-fluoroalkyl analogs of beta-CIT. J Nucl Med. 1996 Jul; 37(7):1129-33.
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    339. Bremner JD, Krystal JH, Charney DS, Southwick SM. Neural mechanisms in dissociative amnesia for childhood abuse: relevance to the current controversy surrounding the "false memory syndrome". Am J Psychiatry. 1996 Jul; 153(7 Suppl):71-82.
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    340. Johnson DR, Rosenheck R, Fontana A, Lubin H, Charney D, Southwick S. Outcome of intensive inpatient treatment for combat-related posttraumatic stress disorder. Am J Psychiatry. 1996 Jun; 153(6):771-7.
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    341. Mason J, Weizman R, Laor N, Wang S, Schujovitsky A, Abramovitz-Schneider P, Feiler D, Charney D. Serum triiodothyronine elevation with posttraumatic stress disorder: a cross-cultural study. Biol Psychiatry. 1996 May 15; 39(10):835-8.
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    342. Bremner JD, Krystal JH, Southwick SM, Charney DS. Noradrenergic mechanisms in stress and anxiety: I. Preclinical studies. Synapse. 1996 May; 23(1):28-38.
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    343. Bremner JD, Krystal JH, Southwick SM, Charney DS. Noradrenergic mechanisms in stress and anxiety: II. Clinical studies. Synapse. 1996 May; 23(1):39-51.
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    344. Miller HL, Delgado PL, Salomon RM, Heninger GR, Charney DS. Effects of alpha-methyl-para-tyrosine (AMPT) in drug-free depressed patients. Neuropsychopharmacology. 1996 Mar; 14(3):151-7.
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    345. Bremner JD, Southwick SM, Darnell A, Charney DS. Chronic PTSD in Vietnam combat veterans: course of illness and substance abuse. Am J Psychiatry. 1996 Mar; 153(3):369-75.
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    346. Miller HL, Delgado PL, Salomon RM, Berman R, Krystal JH, Heninger GR, Charney DS. Clinical and biochemical effects of catecholamine depletion on antidepressant-induced remission of depression. Arch Gen Psychiatry. 1996 Feb; 53(2):117-28.
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    347. Seibyl JP, Laruelle M, van Dyck CH, Wallace E, Baldwin RM, Zoghbi S, Zea-Ponce Y, Neumeyer JL, Charney DS, Hoffer PB, Innis RB. Reproducibility of iodine-123-beta-CIT SPECT brain measurement of dopamine transporters. J Nucl Med. 1996 Feb; 37(2):222-8.
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    348. Marek KL, Seibyl JP, Zoghbi SS, Zea-Ponce Y, Baldwin RM, Fussell B, Charney DS, van Dyck C, Hoffer PB, Innis RP. [123I] beta-CIT/SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease. Neurology. 1996 Jan; 46(1):231-7.
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    349. Charney DS, Deutch A. A functional neuroanatomy of anxiety and fear: implications for the pathophysiology and treatment of anxiety disorders. Crit Rev Neurobiol. 1996; 10(3-4):419-46.
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    350. van Dyck CH, Seibyl JP, Stubbs JB, Zoghbi S, Wisniewski G, Baldwin RM, Zea-Ponce Y, Charney DS, Hoffer PB, Innis RB. Human biodistribution and dosimetry of the SPECT D2 dopamine receptor radioligand [123I]IBF. Nucl Med Biol. 1996 Jan; 23(1):9-16.
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    351. Lam RW, Zis AP, Grewal A, Delgado PL, Charney DS, Krystal JH. Effects of rapid tryptophan depletion in patients with seasonal affective disorder in remission after light therapy. Arch Gen Psychiatry. 1996 Jan; 53(1):41-4.
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    352. Morgan CA, Grillon C, Southwick SM, Davis M, Charney DS. Exaggerated acoustic startle reflex in Gulf War veterans with posttraumatic stress disorder. Am J Psychiatry. 1996 Jan; 153(1):64-8.
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    353. Karper LP, Freeman GK, Grillon C, Morgan CA, Charney DS, Krystal JH. Preliminary evidence of an association between sensorimotor gating and distractibility in psychosis. J Neuropsychiatry Clin Neurosci. 1996; 8(1):60-6.
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    354. Freimer M, Kranzler H, Satel S, Lacobelle J, Skipsey K, Charney D, Gelernter J. No association between D3 dopamine receptor (DRD3) alleles and cocaine dependence. Addict Biol. 1996; 1(3):281-7.
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    355. Heninger GR, Delgado PL, Charney DS. The revised monoamine theory of depression: a modulatory role for monoamines, based on new findings from monoamine depletion experiments in humans. Pharmacopsychiatry. 1996 Jan; 29(1):2-11.
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    356. Krystal JH, Deutsch DN, Charney DS. The biological basis of panic disorder. J Clin Psychiatry. 1996; 57 Suppl 10:23-31; discussion 32-3.
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    357. Krystal JH, Webb E, Cooney NL, Kranzler HR, Southwick SW, Heninger GR, Charney DS. Serotonergic and noradrenergic dysregulation in alcoholism: m-chlorophenylpiperazine and yohimbine effects in recently detoxified alcoholics and healthy comparison subjects. Am J Psychiatry. 1996 Jan; 153(1):83-92.
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    358. Seibyl JP, Zea-Ponce Y, Brenner L, Baldwin RM, Krystal JH, Offord SJ, Mochoviak S, Charney DS, Hoffer PB, Innis RB. Continuous intravenous infusion of iodine-123-IBZM for SPECT determination of human brain dopamine receptor occupancy by antipsychotic agent RWJ-37796. J Nucl Med. 1996 Jan; 37(1):11-5.
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    359. Bremner JD, Randall P, Scott TM, Capelli S, Delaney R, McCarthy G, Charney DS. Deficits in short-term memory in adult survivors of childhood abuse. Psychiatry Res. 1995 Nov 29; 59(1-2):97-107.
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    360. Stine SM, Krystal JH, Kosten TR, Charney DS. Mazindol treatment for cocaine dependence. Drug Alcohol Depend. 1995 Oct; 39(3):245-52.
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    361. Bremner JD, Krystal JH, Southwick SM, Charney DS. Functional neuroanatomical correlates of the effects of stress on memory. J Trauma Stress. 1995 Oct; 8(4):527-53.
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    362. Seibyl JP, Marek KL, Quinlan D, Sheff K, Zoghbi S, Zea-Ponce Y, Baldwin RM, Fussell B, Smith EO, Charney DS, van Dyck C, et al. Decreased single-photon emission computed tomographic [123I]beta-CIT striatal uptake correlates with symptom severity in Parkinson's disease. Ann Neurol. 1995 Oct; 38(4):589-98.
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    363. Morgan CA, Grillon C, Southwick SM, Davis M, Charney DS. Fear-potentiated startle in posttraumatic stress disorder. Biol Psychiatry. 1995 Sep 15; 38(6):378-85.
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    364. Randall PK, Bremner JD, Krystal JH, Nagy LM, Heninger GR, Nicolaou AL, Charney DS. Effects of the benzodiazepine antagonist flumazenil in PTSD. Biol Psychiatry. 1995 Sep 1; 38(5):319-24.
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    365. Goodman WK, McDougle CJ, Price LH, Barr LC, Hills OF, Caplik JF, Charney DS, Heninger GR. m-Chlorophenylpiperazine in patients with obsessive-compulsive disorder: absence of symptom exacerbation. Biol Psychiatry. 1995 Aug 1; 38(3):138-49.
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    366. Southwick SM, Morgan CA, Darnell A, Bremner D, Nicolaou AL, Nagy LM, Charney DS. Trauma-related symptoms in veterans of Operation Desert Storm: a 2-year follow-up. Am J Psychiatry. 1995 Aug; 152(8):1150-5.
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    367. Goddard AW, Charney DS, Germine M, Woods SW, Heninger GR, Krystal JH, Goodman WK, Price LH. Effects of tryptophan depletion on responses to yohimbine in healthy human subjects. Biol Psychiatry. 1995 Jul 15; 38(2):74-85.
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    368. al-Tikriti MS, Zea-Ponce Y, Baldwin RM, Zoghbi SS, Laruelle M, Seibyl JP, Giddings SS, Scanley BE, Charney DS, Hoffer PB, et al. Characterization of the dopamine transporter in nonhuman primate brain: homogenate binding, whole body imaging, and ex vivo autoradiography using [125I] and [123I]IPCIT. Nucl Med Biol. 1995 Jul; 22(5):649-58.
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    369. van Dyck CH, Seibyl JP, Malison RT, Laruelle M, Wallace E, Zoghbi SS, Zea-Ponce Y, Baldwin RM, Charney DS, Hoffer PB. Age-related decline in striatal dopamine transporter binding with iodine-123-beta-CITSPECT. J Nucl Med. 1995 Jul; 36(7):1175-81.
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    370. Bremner JD, Randall P, Scott TM, Bronen RA, Seibyl JP, Southwick SM, Delaney RC, McCarthy G, Charney DS, Innis RB. MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder. Am J Psychiatry. 1995 Jul; 152(7):973-81.
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    371. Laruelle M, Abi-Dargham A, van Dyck CH, Rosenblatt W, Zea-Ponce Y, Zoghbi SS, Baldwin RM, Charney DS, Hoffer PB, Kung HF, et al. SPECT imaging of striatal dopamine release after amphetamine challenge. J Nucl Med. 1995 Jul; 36(7):1182-90.
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    372. Wang S, Mason J, Southwick S, Johnson D, Lubin H, Charney D. Relationships between thyroid hormones and symptoms in combat-related posttraumatic stress disorder. Psychosom Med. 1995 Jul-Aug; 57(4):398-402.
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    373. Satel SL, Krystal JH, Delgado PL, Kosten TR, Charney DS. Tryptophan depletion and attenuation of cue-induced craving for cocaine. Am J Psychiatry. 1995 May; 152(5):778-83.
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    374. McDougle CJ, Krystal JH, Price LH, Heninger GR, Charney DS. Noradrenergic response to acute ethanol administration in healthy subjects: comparison with intravenous yohimbine. Psychopharmacology (Berl). 1995 Mar; 118(2):127-35.
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    375. Abi-Dargham A, Gandelman M, Zoghbi SS, Laruelle M, Baldwin RM, Randall P, Zea-Ponce Y, Charney DS, Hoffer PB, Innis RB. Reproducibility of SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil. J Nucl Med. 1995 Feb; 36(2):167-75.
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    376. Morgan CA, Grillon C, Southwick SM, Nagy LM, Davis M, Krystal JH, Charney DS. Yohimbine facilitated acoustic startle in combat veterans with post-traumatic stress disorder. Psychopharmacology (Berl). 1995 Feb; 117(4):466-71.
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    377. Krystal JH, Woods SW, Kosten TR, Rosen MI, Seibyl JP, van Dyck CC, Price LH, Zubal IG, Hoffer PB, Charney DS. Opiate dependence and withdrawal: preliminary assessment using single photon emission computerized tomography (SPECT). Am J Drug Alcohol Abuse. 1995 Feb; 21(1):47-63.
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    378. Baldwin RM, Zea-Ponce Y, al-Tikriti MS, Zoghbi SS, Seibyl JP, Charney DS, Hoffer PB, Wang S, Milius RA, Neumeyer JL, et al. Regional brain uptake and pharmacokinetics of [123I]N-omega-fluoroalkyl-2 beta-carboxy-3 beta-(4-iodophenyl)nortropane esters in baboons. Nucl Med Biol. 1995 Feb; 22(2):211-9.
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    379. Scanley BE, al-Tikriti MS, Gandelman MS, Laruelle M, Zea-Ponce Y, Baldwin RM, Zoghbi SS, Hoffer PB, Charney DS, Wang S, et al. Comparison of [123I]beta-CIT and [123I]IPCIT as single-photon emission tomography radiotracers for the dopamine transporter in nonhuman primates. Eur J Nucl Med. 1995 Jan; 22(1):4-11.
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    380. Blake DD, Weathers FW, Nagy LM, Kaloupek DG, Gusman FD, Charney DS, Keane TM. The development of a Clinician-Administered PTSD Scale. J Trauma Stress. 1995 Jan; 8(1):75-90.
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    381. Rosenheck R, Charney DS, Frisman LK, Cramer J. Clozapine's cost effectiveness. Am J Psychiatry. 1995 Jan; 152(1):152-3.
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    382. Salomon RM, Delgado PL, Licinio J, Krystal JH, Heninger GR, Charney DS. Effects of sleep deprivation on serotonin function in depression. Biol Psychiatry. 1994 Dec 15; 36(12):840-6.
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    383. Goddard AW, Sholomskas DE, Walton KE, Augeri FM, Charney DS, Heninger GR, Goodman WK, Price LH. Effects of tryptophan depletion in panic disorder. Biol Psychiatry. 1994 Dec 1; 36(11):775-7.
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    384. Anand A, Charney DS, Delgado PL, McDougle CJ, Heninger GR, Price LH. Neuroendocrine and behavioral responses to intravenous m-chlorophenylpiperazine (mCPP) in depressed patients and healthy comparison subjects. Am J Psychiatry. 1994 Nov; 151(11):1626-30.
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    385. Krystal JH, Webb E, Cooney N, Kranzler HR, Charney DS. Specificity of ethanollike effects elicited by serotonergic and noradrenergic mechanisms. Arch Gen Psychiatry. 1994 Nov; 51(11):898-911.
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    386. Delgado PL, Price LH, Miller HL, Salomon RM, Aghajanian GK, Heninger GR, Charney DS. Serotonin and the neurobiology of depression. Effects of tryptophan depletion in drug-free depressed patients. Arch Gen Psychiatry. 1994 Nov; 51(11):865-74.
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    387. Laruelle M, Wallace E, Seibyl JP, Baldwin RM, Zea-Ponce Y, Zoghbi SS, Neumeyer JL, Charney DS, Hoffer PB, Innis RB. Graphical, kinetic, and equilibrium analyses of in vivo [123I] beta-CIT binding to dopamine transporters in healthy human subjects. J Cereb Blood Flow Metab. 1994 Nov; 14(6):982-94.
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    388. Germine M, Goddard AW, Sholomskas DE, Woods SW, Charney DS, Heninger GR. Response to meta-chlorophenylpiperazine in panic disorder patients and healthy subjects: influence of reduction in intravenous dosage. Psychiatry Res. 1994 Nov; 54(2):115-33.
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    389. Baldwin RM, Zea-Ponce Y, Zoghbi SS, al-Tikriti MS, Seibyl JP, Sybirska EH, Malison RT, Laruelle M, Charney DS, Hoffer PB, et al. Pharmacokinetics of the three radioiodinated dopamine D2 receptor ligands [123I]IBF, [123I]epidepride and [123I]2'-ISP in nonhuman primates. Nucl Med Biol. 1994 Oct; 21(7):969-76.
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    390. Laruelle M, al-Tikriti MS, Zea-Ponce Y, Zoghbi SS, Baldwin RM, Charney DS, Hoffer PB, Kung HF, Innis RB. In vivo quantification of dopamine D2 receptor parameters in nonhuman primates with [123I]iodobenzofuran and single photon emission computerized tomography. Eur J Pharmacol. 1994 Sep 22; 263(1-2):39-51.
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    391. Southwick SM, Bremner D, Krystal JH, Charney DS. Psychobiologic research in post-traumatic stress disorder. Psychiatr Clin North Am. 1994 Jun; 17(2):251-64.
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    392. Laruelle M, Baldwin RM, Rattner Z, al-Tikriti MS, Zea-Ponce Y, Zoghbi SS, Charney DS, Price JC, Frost JJ, Hoffer PB, et al. SPECT quantification of [123I]iomazenil binding to benzodiazepine receptors in nonhuman primates: I. Kinetic modeling of single bolus experiments. J Cereb Blood Flow Metab. 1994 May; 14(3):439-52.
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    393. Laruelle M, Abi-Dargham A, al-Tikriti MS, Baldwin RM, Zea-Ponce Y, Zoghbi SS, Charney DS, Hoffer PB, Innis RB. SPECT quantification of [123I]iomazenil binding to benzodiazepine receptors in nonhuman primates: II. Equilibrium analysis of constant infusion experiments and correlation with in vitro parameters. J Cereb Blood Flow Metab. 1994 May; 14(3):453-65.
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    394. Goldstein RB, Weissman MM, Adams PB, Horwath E, Lish JD, Charney D, Woods SW, Sobin C, Wickramaratne PJ. Psychiatric disorders in relatives of probands with panic disorder and/or major depression. Arch Gen Psychiatry. 1994 May; 51(5):383-94.
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    395. Laruelle M, van Dyck C, Abi-Dargham A, Zea-Ponce Y, Zoghbi SS, Charney DS, Baldwin RM, Hoffer PB, Kung HF, Innis RB. Compartmental modeling of iodine-123-iodobenzofuran binding to dopamine D2 receptors in healthy subjects. J Nucl Med. 1994 May; 35(5):743-54.
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    396. Salomon RM, Mazure CM, Delgado PL, Mendia P, Charney DS. Serotonin function in aggression: the effect of acute plasma tryptophan depletion in aggressive patients. Biol Psychiatry. 1994 Apr 15; 35(8):570-2.
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    397. Johnson DR, Feldman SC, Southwick SM, Charney DS. The concept of the Second Generation program in the treatment of post-traumatic stress disorder among Vietnam veterans. J Trauma Stress. 1994 Apr; 7(2):217-35.
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    398. Barr LC, Goodman WK, McDougle CJ, Delgado PL, Heninger GR, Charney DS, Price LH. Tryptophan depletion in patients with obsessive-compulsive disorder who respond to serotonin reuptake inhibitors. Arch Gen Psychiatry. 1994 Apr; 51(4):309-17.
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    399. Laruelle M, Giddings SS, Zea-Ponce Y, Charney DS, Neumeyer JL, Baldwin RM, Innis RB. Methyl 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylate in vitro binding to dopamine and serotonin transporters under "physiological" conditions. J Neurochem. 1994 Mar; 62(3):978-86.
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    400. Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB, Charney DS. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry. 1994 Mar; 51(3):199-214.
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    401. Dey HM, Seibyl JP, Stubbs JB, Zoghbi SS, Baldwin RM, Smith EO, Zubal IG, Zea-Ponce Y, Olson C, Charney DS, et al. Human biodistribution and dosimetry of the SPECT benzodiazepine receptor radioligand iodine-123-iomazenil. J Nucl Med. 1994 Mar; 35(3):399-404.
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    402. al-Tikriti MS, Baldwin RM, Zea-Ponce Y, Sybirska E, Zoghbi SS, Laruelle M, Malison RT, Kung HF, Kessler RM, Charney DS, et al. Comparison of three high affinity SPECT radiotracers for the dopamine D2 receptor. Nucl Med Biol. 1994 Feb; 21(2):179-88.
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    403. Abi-Dargham A, Laruelle M, Seibyl J, Rattner Z, Baldwin RM, Zoghbi SS, Zea-Ponce Y, Bremner JD, Hyde TM, Charney DS, et al. SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil: kinetic and equilibrium paradigms. J Nucl Med. 1994 Feb; 35(2):228-38.
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    404. Scanley BE, Baldwin RM, Laruelle M, al-Tikriti MS, Zea-Ponce Y, Zoghbi S, Giddings SS, Charney DS, Hoffer PB, Wang S, et al. Active and inactive enantiomers of 2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: comparison using homogenate binding and single photon emission computed tomographic imaging. Mol Pharmacol. 1994 Jan; 45(1):136-41.
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    405. Salomon RM, Miller HL, Delgado PL, Charney D. The use of tryptophan depletion to evaluate central serotonin function in depression and other neuropsychiatric disorders. Int Clin Psychopharmacol. 1993 Nov; 8 Suppl 2:41-6.
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    406. Malison RT, Miller EG, Greene R, McCarthy G, Charney DS, Innis RB. Computer-assisted coregistration of multislice SPECT and MR brain images by fixed external fiducials. J Comput Assist Tomogr. 1993 Nov-Dec; 17(6):952-60.
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    407. Weissman MM, Wickramaratne P, Adams PB, Lish JD, Horwath E, Charney D, Woods SW, Leeman E, Frosch E. The relationship between panic disorder and major depression. A new family study. Arch Gen Psychiatry. 1993 Oct; 50(10):767-80.
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    408. Southwick SM, Morgan A, Nagy LM, Bremner D, Nicolaou AL, Johnson DR, Rosenheck R, Charney DS. Trauma-related symptoms in veterans of Operation Desert Storm: a preliminary report. Am J Psychiatry. 1993 Oct; 150(10):1524-8.
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    409. Licinio J, Seibyl JP, Altemus M, Charney DS, Krystal JH. Elevated CSF levels of interleukin-2 in neuroleptic-free schizophrenic patients. Am J Psychiatry. 1993 Sep; 150(9):1408-10.
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    410. Krystal JH, Seibyl JP, Price LH, Woods SW, Heninger GR, Aghajanian GK, Charney DS. m-Chlorophenylpiperazine effects in neuroleptic-free schizophrenic patients. Evidence implicating serotonergic systems in the positive symptoms of schizophrenia. Arch Gen Psychiatry. 1993 Aug; 50(8):624-35.
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    411. Goddard AW, Woods SW, Sholomskas DE, Goodman WK, Charney DS, Heninger GR. Effects of the serotonin reuptake inhibitor fluvoxamine on yohimbine-induced anxiety in panic disorder. Psychiatry Res. 1993 Aug; 48(2):119-33.
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    412. Friedman MJ, Charney DS, Southwick SM. Pharmacotherapy for recently evacuated military casualties. Mil Med. 1993 Jul; 158(7):493-7.
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    413. Bremner JD, Steinberg M, Southwick SM, Johnson DR, Charney DS. Use of the Structured Clinical Interview for DSM-IV Dissociative Disorders for systematic assessment of dissociative symptoms in posttraumatic stress disorder. Am J Psychiatry. 1993 Jul; 150(7):1011-4.
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    414. Bremner JD, Scott TM, Delaney RC, Southwick SM, Mason JW, Johnson DR, Innis RB, McCarthy G, Charney DS. Deficits in short-term memory in posttraumatic stress disorder. Am J Psychiatry. 1993 Jul; 150(7):1015-9.
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    415. Charney DS, Deutch AY, Krystal JH, Southwick SM, Davis M. Psychobiologic mechanisms of posttraumatic stress disorder. Arch Gen Psychiatry. 1993 Apr; 50(4):295-305.
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    416. Southwick SM, Krystal JH, Morgan CA, Johnson D, Nagy LM, Nicolaou A, Heninger GR, Charney DS. Abnormal noradrenergic function in posttraumatic stress disorder. Arch Gen Psychiatry. 1993 Apr; 50(4):266-74.
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    417. Nagy LM, Morgan CA, Southwick SM, Charney DS. Open prospective trial of fluoxetine for posttraumatic stress disorder. J Clin Psychopharmacol. 1993 Apr; 13(2):107-13.
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    418. Bremner JD, Southwick SM, Johnson DR, Yehuda R, Charney DS. Childhood physical abuse and combat-related posttraumatic stress disorder in Vietnam veterans. Am J Psychiatry. 1993 Feb; 150(2):235-9.
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    419. Nagy LM, Krystal JH, Charney DS, Merikangas KR, Woods SW. Long-term outcome of panic disorder after short-term imipramine and behavioral group treatment: 2.9-year naturalistic follow-up study. J Clin Psychopharmacol. 1993 Feb; 13(1):16-24.
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    420. Laruelle M, Abi-Dargham A, Rattner Z, al-Tikriti MS, Zea-Ponce Y, Zoghbi SS, Charney DS, Price J, Frost JJ, Hoffer PB, et al. Single photon emission tomography measurement of benzodiazepine receptor number and affinity in primate brain: a constant infusion paradigm with [123I]iomazenil. Eur J Pharmacol. 1993 Jan 5; 230(1):119-23.
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    421. Morgan CA, Southwick SM, Grillon C, Davis M, Krystal JH, Charney DS. Yohimbine-facilitated acoustic startle reflex in humans. Psychopharmacology (Berl). 1993; 110(3):342-6.
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    422. Seibyl JP, Satel SL, Anthony D, Southwick SM, Krystal JH, Charney DS. Effects of cocaine on hospital course in schizophrenia. J Nerv Ment Dis. 1993 Jan; 181(1):31-7.
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    423. Delgado PL, Miller HL, Salomon RM, Licinio J, Heninger GR, Gelenberg AJ, Charney DS. Monoamines and the mechanism of antidepressant action: effects of catecholamine depletion on mood of patients treated with antidepressants. Psychopharmacol Bull. 1993; 29(3):389-96.
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    424. Yehuda R, Southwick SM, Krystal JH, Bremner D, Charney DS, Mason JW. Enhanced suppression of cortisol following dexamethasone administration in posttraumatic stress disorder. Am J Psychiatry. 1993 Jan; 150(1):83-6.
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    425. Grillon C, Ameli R, Charney DS, Krystal J, Braff D. Startle gating deficits occur across prepulse intensities in schizophrenic patients. Biol Psychiatry. 1992 Nov 15; 32(10):939-43.
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    426. Miller HL, Delgado PL, Salomon RM, Licinio J, Barr LC, Charney DS. Acute tryptophan depletion: a method of studying antidepressant action. J Clin Psychiatry. 1992 Oct; 53 Suppl:28-35.
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    427. Charney DS, Woods SW, Krystal JH, Nagy LM, Heninger GR. Noradrenergic neuronal dysregulation in panic disorder: the effects of intravenous yohimbine and clonidine in panic disorder patients. Acta Psychiatr Scand. 1992 Oct; 86(4):273-82.
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    428. Germine M, Goddard AW, Woods SW, Charney DS, Heninger GR. Anger and anxiety responses to m-chlorophenylpiperazine in generalized anxiety disorder. Biol Psychiatry. 1992 Sep 1; 32(5):457-61.
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    429. Woods SW, Seibyl JP, Goddard AW, Dey HM, Zoghbi SS, Germine M, Baldwin RM, Smith EO, Charney DS, Heninger GR, et al. Dynamic SPECT imaging after injection of the benzodiazepine receptor ligand [123I]iomazenil in healthy human subjects. Psychiatry Res. 1992 Aug; 45(2):67-77.
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    430. Price LH, Charney DS, Heninger GR. Serotonin syndrome. Am J Psychiatry. 1992 Aug; 149(8):1116-7.
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    431. Heninger GR, Delgado PL, Charney DS, Price LH, Aghajanian GK. Tryptophan-deficient diet and amino acid drink deplete plasma tryptophan and induce a relapse of depression in susceptible patients. J Chem Neuroanat. 1992 Jul-Aug; 5(4):347-8.
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    432. Seibyl JP, Brenner L, Krystal JH, Johnson R, Charney DS. Mazindol and cocaine addiction in schizophrenia. Biol Psychiatry. 1992 Jun 1; 31(11):1179-81.
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    433. Barr LC, Goodman WK, Price LH, McDougle CJ, Charney DS. The serotonin hypothesis of obsessive compulsive disorder: implications of pharmacologic challenge studies. J Clin Psychiatry. 1992 Apr; 53 Suppl:17-28.
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    434. Bremner JD, Southwick S, Brett E, Fontana A, Rosenheck R, Charney DS. Dissociation and posttraumatic stress disorder in Vietnam combat veterans. Am J Psychiatry. 1992 Mar; 149(3):328-32.
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    435. Woods SW, Nagy LM, Koleszar AS, Krystal JH, Heninger GR, Charney DS. Controlled trial of alprazolam supplementation during imipramine treatment of panic disorder. J Clin Psychopharmacol. 1992 Feb; 12(1):32-8.
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    436. Krystal JH, Leaf PJ, Bruce ML, Charney DS. Effects of age and alcoholism on the prevalence of panic disorder. Acta Psychiatr Scand. 1992 Jan; 85(1):77-82.
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    437. Krystal JH, McDougle CJ, Woods SW, Price LH, Heninger GR, Charney DS. Dose-response relationship for oral idazoxan effects in healthy human subjects: comparison with oral yohimbine. Psychopharmacology (Berl). 1992; 108(3):313-9.
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    438. McCance-Katz E, Price LH, Charney DS, Heninger GR. Serotonergic function during lithium augmentation of refractory depression. Psychopharmacology (Berl). 1992; 108(1-2):93-7.
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    439. Krystal JH, McDougle CJ, Kosten TR, Price LH, Aghajanian GK, Charney DS. Baclofen-assisted detoxification from opiates. A pilot study. J Subst Abuse Treat. 1992; 9(2):139-42.
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    440. Satel SL, Price LH, Palumbo JM, McDougle CJ, Krystal JH, Gawin F, Charney DS, Heninger GR, Kleber HD. Clinical phenomenology and neurobiology of cocaine abstinence: a prospective inpatient study. Am J Psychiatry. 1991 Dec; 148(12):1712-6.
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    441. Krystal JH, Woods SW, Hill CL, Charney DS. Characteristics of panic attack subtypes: assessment of spontaneous panic, situational panic, sleep panic, and limited symptom attacks. Compr Psychiatry. 1991 Nov-Dec; 32(6):474-80.
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    442. Price LH, Charney DS, Delgado PL, Heninger GR. Serotonin function and depression: neuroendocrine and mood responses to intravenous L-tryptophan in depressed patients and healthy comparison subjects. Am J Psychiatry. 1991 Nov; 148(11):1518-25.
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    443. McDougle CJ, Southwick SM, Charney DS, St James RL. An open trial of fluoxetine in the treatment of posttraumatic stress disorder. J Clin Psychopharmacol. 1991 Oct; 11(5):325-7.
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    444. Neumeyer JL, Wang SY, Milius RA, Baldwin RM, Zea-Ponce Y, Hoffer PB, Sybirska E, al-Tikriti M, Charney DS, Malison RT, et al. [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: high-affinity SPECT radiotracer of monoamine reuptake sites in brain. J Med Chem. 1991 Oct; 34(10):3144-6.
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    445. Seibyl JP, Krystal JH, Price LH, Woods SW, D'Amico C, Heninger GR, Charney DS. Effects of ritanserin on the behavioral, neuroendocrine, and cardiovascular responses to meta-chlorophenylpiperazine in healthy human subjects. Psychiatry Res. 1991 Sep; 38(3):227-36.
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    446. Innis R, Baldwin R, Sybirska E, Zea Y, Laruelle M, al-Tikriti M, Charney D, Zoghbi S, Smith E, Wisniewski G, et al. Single photon emission computed tomography imaging of monoamine reuptake sites in primate brain with [123I]CIT. Eur J Pharmacol. 1991 Aug 6; 200(2-3):369-70.
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    447. Satel SL, Seibyl JP, Charney DS. Prolonged cocaine psychosis implies underlying major psychopathology. J Clin Psychiatry. 1991 Aug; 52(8):349-50.
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    448. McDougle CJ, Price LH, Goodman WK, Charney DS, Heninger GR. A controlled trial of lithium augmentation in fluvoxamine-refractory obsessive-compulsive disorder: lack of efficacy. J Clin Psychopharmacol. 1991 Jun; 11(3):175-84.
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    449. Deutch AY, Moghaddam B, Innis RB, Krystal JH, Aghajanian GK, Bunney BS, Charney DS. Mechanisms of action of atypical antipsychotic drugs. Implications for novel therapeutic strategies for schizophrenia. Schizophr Res. 1991 Mar-Apr; 4(2):121-56.
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    450. Innis R, Zoghbi S, Johnson E, Woods S, al-Tikriti M, Baldwin R, Seibyl J, Malison R, Zubal G, Charney D, et al. SPECT imaging of the benzodiazepine receptor in non-human primate brain with [123I]Ro 16-0154. Eur J Pharmacol. 1991 Feb 7; 193(2):249-52.
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    451. Woods SW, Charney DS, Silver JM, Krystal JH, Heninger GR. Behavioral, biochemical, and cardiovascular responses to the benzodiazepine receptor antagonist flumazenil in panic disorder. Psychiatry Res. 1991 Feb; 36(2):115-27.
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    452. Delgado PL, Price LH, Miller HL, Salomon RM, Licinio J, Krystal JH, Heninger GR, Charney DS. Rapid serotonin depletion as a provocative challenge test for patients with major depression: relevance to antidepressant action and the neurobiology of depression. Psychopharmacol Bull. 1991; 27(3):321-30.
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    453. Charney DS, Woods SW, Nagy LM, Southwick SM, Krystal JH, Heninger GR. Noradrenergic function in panic disorder. J Clin Psychiatry. 1990 Dec; 51 Suppl A:5-11.
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    454. Woods SW, Charney DS, Delgado PL, Heninger GR. The effect of long-term imipramine treatment on carbon dioxide-induced anxiety in panic disorder patients. J Clin Psychiatry. 1990 Dec; 51(12):505-7.
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    455. Delgado PL, Goodman WK, Price LH, Heninger GR, Charney DS. Fluvoxamine/pimozide treatment of concurrent Tourette's and obsessive-compulsive disorder. Br J Psychiatry. 1990 Nov; 157:762-5.
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    456. Price LH, Charney DS, Delgado PL, Heninger GR. Fenfluramine augmentation in tricyclic-refractory depression. J Clin Psychopharmacol. 1990 Oct; 10(5):312-7.
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    457. Goodman WK, Price LH, Delgado PL, Palumbo J, Krystal JH, Nagy LM, Rasmussen SA, Heninger GR, Charney DS. Specificity of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder. Comparison of fluvoxamine and desipramine. Arch Gen Psychiatry. 1990 Jun; 47(6):577-85.
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    458. Delgado PL, Charney DS, Price LH, Aghajanian GK, Landis H, Heninger GR. Serotonin function and the mechanism of antidepressant action. Reversal of antidepressant-induced remission by rapid depletion of plasma tryptophan. Arch Gen Psychiatry. 1990 May; 47(5):411-8.
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    459. McDougle CJ, Goodman WK, Price LH, Delgado PL, Krystal JH, Charney DS, Heninger GR. Neuroleptic addition in fluvoxamine-refractory obsessive-compulsive disorder. Am J Psychiatry. 1990 May; 147(5):652-4.
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    460. Price LH, Charney DS, Delgado PL, Goodman WK, Krystal JH, Woods SW, Heninger GR. Clinical data on the role of serotonin in the mechanism(s) of action of antidepressant drugs. J Clin Psychiatry. 1990 Apr; 51 Suppl:44-50; discussion 51-2.
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    461. Nierenberg AA, Price LH, Charney DS, Heninger GR. After lithium augmentation: a retrospective follow-up of patients with antidepressant-refractory depression. J Affect Disord. 1990 Mar; 18(3):167-75.
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    462. Kosten TR, Krystal JH, Charney DS, Price LH, Morgan CH, Kleber HD. Opioid antagonist challenges in buprenorphine maintained patients. Drug Alcohol Depend. 1990 Feb; 25(1):73-8.
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    463. Seibyl JP, Krystal JH, Charney DS. Marijuana (cannabis) use is anecdotally said to precipitate anxiety symptoms in patients with panic disorder. Is there any research evidence to support this? Also, can marijuana use precipitate or expose paranoia in patients with an underlying bipolar disorder? J Clin Psychopharmacol. 1990 Feb; 10(1):78.
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    464. Price LH, Charney DS, Delgado PL, Heninger GR. Lithium and serotonin function: implications for the serotonin hypothesis of depression. Psychopharmacology (Berl). 1990; 100(1):3-12.
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    465. Charney DS, Krystal JH, Delgado PL, Heninger GR. Serotonin-specific drugs for anxiety and depressive disorders. Annu Rev Med. 1990; 41:437-46.
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    466. Price LH, Charney DS, Delgado PL, Goodman WK, Krystal JH, Woods SW, Heninger GR. Clinical studies of 5-HT function using i.v. L-tryptophan. Prog Neuropsychopharmacol Biol Psychiatry. 1990; 14(4):459-72.
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    467. Charney DS, Woods SW, Krystal JH, Heninger GR. Serotonin function and human anxiety disorders. Ann N Y Acad Sci. 1990; 600:558-72; discussion 572-3.
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    468. Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale. II. Validity. Arch Gen Psychiatry. 1989 Nov; 46(11):1012-6.
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    469. Charney DS, Woods SW. Benzodiazepine treatment of panic disorder: a comparison of alprazolam and lorazepam. J Clin Psychiatry. 1989 Nov; 50(11):418-23.
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    470. Goodman WK, Price LH, Rasmussen SA, Mazure C, Fleischmann RL, Hill CL, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale. I. Development, use, and reliability. Arch Gen Psychiatry. 1989 Nov; 46(11):1006-11.
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    471. Nagy LM, Krystal JH, Woods SW, Charney DS. Clinical and medication outcome after short-term alprazolam and behavioral group treatment in panic disorder. 2.5 year naturalistic follow-up study. Arch Gen Psychiatry. 1989 Nov; 46(11):993-9.
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    472. Kosten TR, Krystal JH, Charney DS, Price LH, Morgan CH, Kleber HD. Rapid detoxification from opioid dependence. Am J Psychiatry. 1989 Oct; 146(10):1349.
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    473. Price LH, Charney DS, Delgado PL, Anderson GM, Heninger GR. Effects of desipramine and fluvoxamine treatment on the prolactin response to tryptophan. Serotonergic function and the mechanism of antidepressant action. Arch Gen Psychiatry. 1989 Jul; 46(7):625-31.
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    474. Glazer WM, Bowers MB, Charney DS, Heninger GR. The effect of neuroleptic discontinuation on psychopathology, involuntary movements, and biochemical measures in patients with persistent tardive dyskinesia. Biol Psychiatry. 1989 Jul; 26(3):224-33.
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    475. Seibyl JP, Krystal JH, Price LH, Charney DS. Use of yohimbine to counteract nortriptyline-induced orthostatic hypotension. J Clin Psychopharmacol. 1989 Feb; 9(1):67-8.
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    476. Charney DS, Woods SW, Heninger GR. Noradrenergic function in generalized anxiety disorder: effects of yohimbine in healthy subjects and patients with generalized anxiety disorder. Psychiatry Res. 1989 Feb; 27(2):173-82.
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    477. Goodman WK, Price LH, Rasmussen SA, Delgado PL, Heninger GR, Charney DS. Efficacy of fluvoxamine in obsessive-compulsive disorder. A double-blind comparison with placebo. Arch Gen Psychiatry. 1989 Jan; 46(1):36-44.
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    478. Delgado PL, Charney DS, Price LH, Landis H, Heninger GR. Neuroendocrine and behavioral effects of dietary tryptophan restriction in healthy subjects. Life Sci. 1989; 45(24):2323-32.
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    479. Goodman WK, Price LH, Rasmussen SA, Heninger GR, Charney DS. Fluvoxamine as an antiobsessional agent. Psychopharmacol Bull. 1989; 25(1):31-5.
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    480. Charney DS, Innis RB, Duman RS, Woods SW, Heninger GR. Platelet alpha-2-receptor binding and adenylate cyclase activity in panic disorder. Psychopharmacology (Berl). 1989; 98(1):102-7.
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    481. Heninger GR, Charney DS, Price LH, Delgado P, Woods S, Goodman W. Effects of serotonergic agonists on neuroendocrine responses of rhesus monkeys and patients with depression and anxiety disorders. Psychopharmacol Ser. 1989; 7:94-104.
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    482. Woods SW, Krystal JH, Heninger GR, Charney DS. Effects of alprazolam and clonidine on carbon dioxide-induced increases in anxiety ratings in healthy human subjects. Life Sci. 1989; 45(3):233-42.
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    483. Price LH, Charney DS, Delgado PL, Heninger GR. Lithium treatment and serotoninergic function. Neuroendocrine and behavioral responses to intravenous tryptophan in affective disorder. Arch Gen Psychiatry. 1989 Jan; 46(1):13-9.
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    484. Woods SW, Koster K, Krystal JK, Smith EO, Zubal IG, Hoffer PB, Charney DS. Yohimbine alters regional cerebral blood flow in panic disorder. Lancet. 1988 Sep 17; 2(8612):678.
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    485. Salloway S, Price LH, Charney DS, Shapiro M. Multiple sclerosis presenting as major depression: a diagnosis suggested by MRI scan but not CT scan. J Clin Psychiatry. 1988 Sep; 49(9):364-6.
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    486. Heninger GR, Charney DS, Price LH. alpha 2-Adrenergic receptor sensitivity in depression. The plasma MHPG, behavioral, and cardiovascular responses to yohimbine. Arch Gen Psychiatry. 1988 Aug; 45(8):718-26.
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    487. Delgado PL, Price LH, Charney DS, Heninger GR. Efficacy of fluvoxamine in treatment-refractory depression. J Affect Disord. 1988 Jul-Aug; 15(1):55-60.
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    488. Heninger GR, Charney DS. Monoamine receptor systems and anxiety disorders. Psychiatr Clin North Am. 1988 Jun; 11(2):309-26.
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    489. Price LH, Charney DS, Heninger GR. Effects of trazodone treatment on serotonergic function in depressed patients. Psychiatry Res. 1988 May; 24(2):165-75.
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    490. Price LH, Delgado PL, Charney DS, Heninger GR. Sequence of drug administration in lithium augmentation: a case study. J Clin Psychiatry. 1988 Apr; 49(4):161-2.
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    491. Charney DS, Goodman WK, Price LH, Woods SW, Rasmussen SA, Heninger GR. Serotonin function in obsessive-compulsive disorder. A comparison of the effects of tryptophan and m-chlorophenylpiperazine in patients and healthy subjects. Arch Gen Psychiatry. 1988 Feb; 45(2):177-85.
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    492. Woods SW, Charney DS, Goodman WK, Heninger GR. Carbon dioxide-induced anxiety. Behavioral, physiologic, and biochemical effects of carbon dioxide in patients with panic disorders and healthy subjects. Arch Gen Psychiatry. 1988 Jan; 45(1):43-52.
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    493. Brown SL, Charney DS, Woods SW, Heninger GR, Tallman J. Lymphocyte beta-adrenergic receptor binding in panic disorder. Psychopharmacology (Berl). 1988; 94(1):24-8.
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    494. Heninger GR, Charney DS, Price LH. Noradrenergic and serotonergic receptor system function in panic disorder and depression. Acta Psychiatr Scand Suppl. 1988; 341:138-50.
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    495. Woods SW, Krystal JH, D'Amico CL, Heninger GR, Charney DS. A review of behavioral and pharmacologic studies relevant to the application of CO2 as a human subject model of anxiety. Psychopharmacol Bull. 1988; 24(1):149-53.
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    496. Glazer WM, Charney DS, Heninger GR. Noradrenergic function in schizophrenia. Arch Gen Psychiatry. 1987 Oct; 44(10):898-904.
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    497. Price LH, Goodman WK, Charney DS, Rasmussen SA, Heninger GR. Treatment of severe obsessive-compulsive disorder with fluvoxamine. Am J Psychiatry. 1987 Aug; 144(8):1059-61.
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    498. Charney DS, Woods SW, Goodman WK, Heninger GR. Neurobiological mechanisms of panic anxiety: biochemical and behavioral correlates of yohimbine-induced panic attacks. Am J Psychiatry. 1987 Aug; 144(8):1030-6.
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    499. Innis RB, Charney DS, Heninger GR. Differential 3H-imipramine platelet binding in patients with panic disorder and depression. Psychiatry Res. 1987 May; 21(1):33-41.
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    500. Woods SW, Charney DS, McPherson CA, Gradman AH, Heninger GR. Situational panic attacks. Behavioral, physiologic, and biochemical characterization. Arch Gen Psychiatry. 1987 Apr; 44(4):365-75.
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    501. Goodman WK, Charney DS. A case of alprazolam, but not lorazepam, inducing manic symptoms. J Clin Psychiatry. 1987 Mar; 48(3):117-8.
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    502. Charney DS, Woods SW, Goodman WK, Heninger GR. Serotonin function in anxiety. II. Effects of the serotonin agonist MCPP in panic disorder patients and healthy subjects. Psychopharmacology (Berl). 1987; 92(1):14-24.
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    503. Price LH, Charney DS, Heninger GR. Reserpine augmentation of desipramine in refractory depression: clinical and neurobiological effects. Psychopharmacology (Berl). 1987; 92(4):431-7.
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    504. Rasmussen SA, Goodman WK, Woods SW, Heninger GR, Charney DS. Effects of yohimbine in obsessive compulsive disorder. Psychopharmacology (Berl). 1987; 93(3):308-13.
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    505. Charney DS, Price LH, Heninger GR. Desipramine-yohimbine combination treatment of refractory depression. Implications for the beta-adrenergic receptor hypothesis of antidepressant action. Arch Gen Psychiatry. 1986 Dec; 43(12):1155-61.
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    506. Charney DS, Woods SW, Goodman WK, Rifkin B, Kinch M, Aiken B, Quadrino LM, Heninger GR. Drug treatment of panic disorder: the comparative efficacy of imipramine, alprazolam, and trazodone. J Clin Psychiatry. 1986 Dec; 47(12):580-6.
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    507. Price LH, Charney DS, Heninger GR. Variability of response to lithium augmentation in refractory depression. Am J Psychiatry. 1986 Nov; 143(11):1387-92.
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    508. Charney DS, Heninger GR. Alpha 2-adrenergic and opiate receptor blockade. Synergistic effects on anxiety in healthy subjects. Arch Gen Psychiatry. 1986 Nov; 43(11):1037-41.
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    509. Charney DS, Heninger GR. Abnormal regulation of noradrenergic function in panic disorders. Effects of clonidine in healthy subjects and patients with agoraphobia and panic disorder. Arch Gen Psychiatry. 1986 Nov; 43(11):1042-54.
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    510. Charney DS, Heninger GR. Serotonin function in panic disorders. The effect of intravenous tryptophan in healthy subjects and patients with panic disorder before and during alprazolam treatment. Arch Gen Psychiatry. 1986 Nov; 43(11):1059-65.
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    511. Breier A, Charney DS, Heninger GR. Agoraphobia with panic attacks. Development, diagnostic stability, and course of illness. Arch Gen Psychiatry. 1986 Nov; 43(11):1029-36.
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    512. Woods SW, Charney DS, Loke J, Goodman WK, Redmond DE, Heninger GR. Carbon dioxide sensitivity in panic anxiety. Ventilatory and anxiogenic response to carbon dioxide in healthy subjects and patients with panic anxiety before and after alprazolam treatment. Arch Gen Psychiatry. 1986 Sep; 43(9):900-9.
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    513. Price LH, Charney DS, Rubin AL, Heninger GR. Alpha 2-adrenergic receptor function in depression. The cortisol response to yohimbine. Arch Gen Psychiatry. 1986 Sep; 43(9):849-58.
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    514. Breier A, Charney DS, Heninger GR. Intravenous diazepam fails to change growth hormone and cortisol secretion in humans. Psychiatry Res. 1986 Aug; 18(4):293-9.
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    515. Charney DS, Heninger GR, Kleber HD. The combined use of clonidine and naltrexone as a rapid, safe, and effective treatment of abrupt withdrawal from methadone. Am J Psychiatry. 1986 Jul; 143(7):831-7.
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    516. Goodman WK, Charney DS, Price LH, Woods SW, Heninger GR. Ineffectiveness of clonidine in the treatment of the benzodiazepine withdrawal syndrome: report of three cases. Am J Psychiatry. 1986 Jul; 143(7):900-3.
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    517. Innis RB, Bunney BS, Charney DS, Price LH, Glazer WM, Sternberg DE, Rubin AL, Heninger GR. Does the cholecystokinin antagonist proglumide possess antipsychotic activity? Psychiatry Res. 1986 May; 18(1):1-7.
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    518. Matthews J, Akil H, Greden J, Charney D, Weinberg V, Rosenbaum A, Watson SJ. beta-Endorphin/beta-lipotropin immunoreactivity in endogenous depression. Effect of dexamethasone. Arch Gen Psychiatry. 1986 Apr; 43(4):374-81.
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    519. Price LH, Charney DS, Heninger GR. Effects of trazodone treatment on alpha-2 adrenoceptor function in depressed patients. Psychopharmacology (Berl). 1986; 89(1):38-44.
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    520. Charney DS, Breier A, Jatlow PI, Heninger GR. Behavioral, biochemical, and blood pressure responses to alprazolam in healthy subjects: interactions with yohimbine. Psychopharmacology (Berl). 1986; 88(2):133-40.
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    521. Charney DS, Heninger GR, Price LH, Breier A. Major depression and panic disorder: diagnostic and neurobiological relationships. Psychopharmacol Bull. 1986; 22(2):503-11.
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    522. Goodman WK, Charney DS. Therapeutic applications and mechanisms of action of monoamine oxidase inhibitor and heterocyclic antidepressant drugs. J Clin Psychiatry. 1985 Oct; 46(10 Pt 2):6-24.
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    523. Price LH, Charney DS, Heninger GR. Effects of tranylcypromine treatment on neuroendocrine, behavioral, and autonomic responses to tryptophan in depressed patients. Life Sci. 1985 Sep 2; 37(9):809-18.
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    524. Breier A, Charney DS, Heninger GR. The diagnostic validity of anxiety disorders and their relationship to depressive illness. Am J Psychiatry. 1985 Jul; 142(7):787-97.
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    525. Rubin AL, Price LH, Charney DS, Heninger GR. Noradrenergic function and the cortisol response to dexamethasone in depression. Psychiatry Res. 1985 May; 15(1):5-15.
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    526. Charney DS, Heninger GR. Noradrenergic function and the mechanism of action of antianxiety treatment. II. The effect of long-term imipramine treatment. Arch Gen Psychiatry. 1985 May; 42(5):473-81.
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    527. Charney DS, Heninger GR. Noradrenergic function and the mechanism of action of antianxiety treatment. I. The effect of long-term alprazolam treatment. Arch Gen Psychiatry. 1985 May; 42(5):458-67.
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    528. Price LH, Charney DS, Heninger GR. Efficacy of lithium-tranylcypromine treatment in refractory depression. Am J Psychiatry. 1985 May; 142(5):619-23.
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    529. Kleber HD, Riordan CE, Rounsaville B, Kosten T, Charney D, Gaspari J, Hogan I, O'Connor C. Clonidine in outpatient detoxification from methadone maintenance. Arch Gen Psychiatry. 1985 Apr; 42(4):391-4.
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    530. Rubin AL, Charney DS, Price LH, Heninger GR. Rapid improvement of delusional depression following drug-induced seizures: case report. J Clin Psychiatry. 1985 Apr; 46(4):146-7.
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    531. Charney DS, Heninger GR, Jatlow PI. Increased anxiogenic effects of caffeine in panic disorders. Arch Gen Psychiatry. 1985 Mar; 42(3):233-43.
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    532. Breier A, Charney DS, Heninger GR. Major depression in patients with agoraphobia and panic disorder. Arch Gen Psychiatry. 1984 Dec; 41(12):1129-35.
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    533. Breier A, Charney DS, Nelson JC. Seizures induced by abrupt discontinuation of alprazolam. Am J Psychiatry. 1984 Dec; 141(12):1606-7.
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    534. Price LH, Charney DS, Heninger GR. Manic symptoms following addition of lithium to antidepressant treatment. J Clin Psychopharmacol. 1984 Dec; 4(6):361-2.
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    535. Price LH, Charney DS, Heninger GR. Three cases of manic symptoms following yohimbine administration. Am J Psychiatry. 1984 Oct; 141(10):1267-8.
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    536. Charney DS, Redmond DE, Galloway MP, Kleber HD, Heninger GR, Murberg M, Roth RH. Naltrexone precipitated opiate withdrawal in methadone addicted human subjects: evidence for noradrenergic hyperactivity. Life Sci. 1984 Sep 17; 35(12):1263-72.
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    537. Charney DS, Heninger GR, Breier A. Noradrenergic function in panic anxiety. Effects of yohimbine in healthy subjects and patients with agoraphobia and panic disorder. Arch Gen Psychiatry. 1984 Aug; 41(8):751-63.
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    538. Charney DS, Galloway MP, Heninger GR. The effects of caffeine on plasma MHPG, subjective anxiety, autonomic symptoms and blood pressure in healthy humans. Life Sci. 1984 Jul 9; 35(2):135-44.
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    539. Charney DS, Heninger GR, Sternberg DE. Serotonin function and mechanism of action of antidepressant treatment. Effects of amitriptyline and desipramine. Arch Gen Psychiatry. 1984 Apr; 41(4):359-65.
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    540. Breier A, Ginsberg EM, Charney DS. Seminal emission induced by tricyclic antidepressant. Am J Psychiatry. 1984 Apr; 141(4):610-11.
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    541. Heninger GR, Charney DS, Sternberg DE. Serotonergic function in depression. Prolactin response to intravenous tryptophan in depressed patients and healthy subjects. Arch Gen Psychiatry. 1984 Apr; 41(4):398-402.
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    542. Charney DS, Heninger GR, Sternberg DE. The effect of mianserin on alpha-2 adrenergic receptor function in depressed patients. Br J Psychiatry. 1984 Apr; 144:407-16.
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    543. Price LH, Nelson JC, Charney DS, Quinlan DM. Family history in delusional depression. J Affect Disord. 1984 Feb; 6(1):109-14.
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    544. Price LH, Nelson JC, Charney DS, Quinlan DM. The clinical utility of family history for the diagnosis of melancholia. J Nerv Ment Dis. 1984 Jan; 172(1):5-11.
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    545. Charney DS, Redmond DE. Neurobiological mechanisms in human anxiety. Evidence supporting central noradrenergic hyperactivity. Neuropharmacology. 1983 Dec; 22(12B):1531-6.
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    546. Heninger GR, Charney DS, Sternberg DE. Lithium carbonate augmentation of antidepressant treatment. An effective prescription for treatment-refractory depression. Arch Gen Psychiatry. 1983 Dec; 40(12):1335-42.
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    547. Sternberg DE, Bowers MB, Heninger GR, Charney DS. Lithium prevents adaptation of brain dopamine systems to haloperidol in schizophrenic patients. Psychiatry Res. 1983 Oct; 10(2):79-86.
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    548. Charney DS, Heninger GR, Redmond DE. Yohimbine induced anxiety and increased noradrenergic function in humans: effects of diazepam and clonidine. Life Sci. 1983 Jul 4; 33(1):19-29.
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    549. Charney DS, Heninger GR, Sternberg DE. Alpha-2 adrenergic receptor sensitivity and the mechanism of action of antidepressant therapy. The effect of long-term amitriptyline treatment. Br J Psychiatry. 1983 Mar; 142:265-75.
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    550. Swann AC, Elsworth JD, Charney DS, Jablons DM, Roth RH, Redmond DE, Maas JW. Brain catecholamine metabolites and behavior in morphine withdrawal. Eur J Pharmacol. 1982 Dec 24; 86(2):167-75.
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    551. Charney DS, Riordan CE, Kleber HD, Murburg M, Braverman P, Sternberg DE, Heninger GR, Redmond DE. Clonidine and naltrexone. A safe, effective, and rapid treatment of abrupt withdrawal from methadone therapy. Arch Gen Psychiatry. 1982 Nov; 39(11):1327-32.
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    552. Charney DS, Heninger GR, Sternberg DE. Failure of chronic antidepressant treatment to alter growth hormone response to clonidine. Psychiatry Res. 1982 Oct; 7(2):135-8.
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    553. Charney DS, Heninger GR, Sternberg DE, Landis H. Abrupt discontinuation of tricyclic antidepressant drugs: evidence for noradrenergic hyperactivity. Br J Psychiatry. 1982 Oct; 141:377-86.
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    554. Charney DS, Heninger GR, Sternberg DE. Assessment of alpha 2 adrenergic autoreceptor function in humans: effects of oral yohimbine. Life Sci. 1982 Jun 7; 30(23):2033-41.
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    555. Charney DS, Heninger GR, Sternberg DE, Hafstad KM, Giddings S, Landis DH. Adrenergic receptor sensitivity in depression. Effects of clonidine in depressed patients and healthy subjects. Arch Gen Psychiatry. 1982 Mar; 39(3):290-4.
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    556. Sternberg DE, Charney DS, Heninger GR, Leckman JF, Hafstad KM, Landis DH. Impaired presynaptic regulation of norepinephrine in schizophrenia. Effects of clonidine in schizophrenic patients and normal controls. Arch Gen Psychiatry. 1982 Mar; 39(3):285-9.
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    557. Charney DS, Heninger GR, Reinhard JF, Sternberg DE, Hafstead KM. The effect of IV L-tryptophan on prolactin, growth hormone, and mood in healthy subjects. Psychopharmacology (Berl). 1982; 78(1):38-43.
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    558. Charney DS, Heninger GR, Reinhard JF, Sternberg DE, Hafstead KM. The effect of intravenous L-tryptophan on prolactin and growth hormone and mood in healthy subjects. Psychopharmacology (Berl). 1982; 77(3):217-22.
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    559. Charney DS, Nelson JC, Quinlan DM. Personality traits and disorder in depression. Am J Psychiatry. 1981 Dec; 138(12):1601-4.
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    560. Charney DS, Heninger GR, Sternberg DE, Redmond DE, Leckman JF, Maas JW, Roth RH. Presynaptic adrenergic receptor sensitivity in depression. The effect of long-term desipramine treatment. Arch Gen Psychiatry. 1981 Dec; 38(12):1334-40.
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    561. Charney DS, Sternberg DE, Kleber HD, Heninger GR, Redmond DE. The clinical use of clonidine in abrupt withdrawal from methadone. Effects on blood pressure and specific signs and symptoms. Arch Gen Psychiatry. 1981 Nov; 38(11):1273-7.
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    562. Charney DS, Menkes DB, Heninger GR. Receptor sensitivity and the mechanism of action of antidepressant treatment. Implications for the etiology and therapy of depression. Arch Gen Psychiatry. 1981 Oct; 38(10):1160-80.
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    563. Charney DS, Heninger GR, Sternberg DE, Roth RH. Plasma MHPG in depression: effects of acute and chronic desipramine treatment. Psychiatry Res. 1981 Oct; 5(2):217-29.
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    564. Nelson JC, Charney DS, Quinlan DM. Evaluation of the DSM-III criteria for melancholia. Arch Gen Psychiatry. 1981 May; 38(5):555-9.
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    565. Charney DS, Nelson JC. Delusional and nondelusional unipolar depression: further evidence for distinct subtypes. Am J Psychiatry. 1981 Mar; 138(3):328-33.
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    566. Nelson JC, Charney DS. The symptoms of major depressive illness. Am J Psychiatry. 1981 Jan; 138(1):1-13.
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    567. Kales JD, Kales A, Soldatos CR, Caldwell AB, Charney DS, Martin ED. Night terrors. Clinical characteristics and personality patterns. Arch Gen Psychiatry. 1980 Dec; 37(12):1413-7.
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    568. Kales A, Soldatos CR, Caldwell AB, Kales JD, Humphrey FJ, Charney DS, Schweitzer PK. Somnambulism. Clinical characteristics and personality patterns. Arch Gen Psychiatry. 1980 Dec; 37(12):1406-10.
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    569. Nelson JC, Charney DS, Quinlan DM. Characteristics of autonomous depression. J Nerv Ment Dis. 1980 Nov; 168(11):637-43.
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    570. Handford AH, Charney D, Ackerman L, Eyster ME, Bixler EO. Effect of psychiatric intervention on use of antihemophilic factor concentrate. Am J Psychiatry. 1980 Oct; 137(10):1254-6.
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    571. Kales A, Soldatos CR, Caldwell AB, Charney DS, Kales JD, Markel D, Cadieux R. Nightmares: clinical characteristics and personality patterns. Am J Psychiatry. 1980 Oct; 137(10):1197-201.
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    572. Charney DS, Kleber HD. Iatrogenic opiate addiction: successful detoxification with clonidine. Am J Psychiatry. 1980 Aug; 137(8):989-90.
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    573. Kales A, Soldatos CR, Bixler EO, Ladda RL, Charney DS, Weber G, Schweitzer PK. Hereditary factors in sleepwalking and night terrors. Br J Psychiatry. 1980 Aug; 137:111-8.
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    574. Nelson JC, Charney DS. Primary affective disorder criteria and the endogenous-reactive distinction. Arch Gen Psychiatry. 1980 Jul; 37(7):787-93.
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    575. Charney DS, Kales A, Soldatos CR, Nelson JC. Somnambulistic-like episodes secondary to combined lithium-neuroleptic treatment. Br J Psychiatry. 1979 Nov; 135:418-24.
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    576. Charney DS. Sleep architecture in psychotropic-induced somnambulism. Am J Psychiatry. 1979 Apr; 136(4A):461.
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    577. Nelson JC, Charney DS, Vingiano AW. False-positive diagnosis with primary-affective-disorder criteria. Lancet. 1978 Dec 9; 2(8102):1252-3.
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    578. Powers WE, Boocks RD, Charney D. Monitoring tracheal tube cuff pressures. Respir Care. 1977 May; 22(5):464, 466, 468-9.
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    579. Graham WP, Miller SH, Gottlieb L, Charney D. Psychological complications of thermal injuries. Pa Med. 1976 Apr; 79(4):58.
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