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Janine D. Flory

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentPsychiatry
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     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Yehuda R, Daskalakis NP, Desarnaud F, Makotkine I, Lehrner AL, Koch E, Flory JD, Buxbaum JD, Meaney MJ, Bierer LM. Epigenetic Biomarkers as Predictors and Correlates of Symptom Improvement Following Psychotherapy in Combat Veterans with PTSD. Front Psychiatry. 2013; 4:118.
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    2. Yehuda R, Neylan TC, Flory JD, McFarlane AC. The use of biomarkers in the military: from theory to practice. Psychoneuroendocrinology. 2013 Sep; 38(9):1912-22.
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    3. Erickson KI, Banducci SE, Weinstein AM, Macdonald AW, Ferrell RE, Halder I, Flory JD, Manuck SB. The brain-derived neurotrophic factor Val66Met polymorphism moderates an effect of physical activity on working memory performance. Psychol Sci. 2013 Sep; 24(9):1770-9.
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    4. Balevich EC, Wein ND, Flory JD. Cigarette smoking and measures of impulsivity in a college sample. Subst Abus. 2013; 34(3):256-62.
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    5. Vella EJ, Kamarck TW, Flory JD, Manuck S. Hostile mood and social strain during daily life: a test of the transactional model. Ann Behav Med. 2012 Dec; 44(3):341-52.
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    6. Flory JD, Yehuda R, Passarelli V, Siever LJ. Joint Effect of Childhood Abuse and Family History of Major Depressive Disorder on Rates of PTSD in People with Personality Disorders. Depress Res Treat. 2012; 2012:350461.
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    7. Sweitzer MM, Halder I, Flory JD, Craig AE, Gianaros PJ, Ferrell RE, Manuck SB. Polymorphic variation in the dopamine D4 receptor predicts delay discounting as a function of childhood socioeconomic status: evidence for differential susceptibility. Soc Cogn Affect Neurosci. 2013 Jun; 8(5):499-508.
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    8. Lahey BB, McNealy K, Knodt A, Zald DH, Sporns O, Manuck SB, Flory JD, Applegate B, Rathouz PJ, Hariri AR. Using confirmatory factor analysis to measure contemporaneous activation of defined neuronal networks in functional magnetic resonance imaging. Neuroimage. 2012 May 1; 60(4):1982-91.
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    9. Morabia A, Zhang FF, Kappil MA, Flory J, Mirer FE, Santella RM, Wolff M, Markowitz SB. Biologic and epigenetic impact of commuting to work by car or using public transportation: a case-control study. Prev Med. 2012 Mar-Apr; 54(3-4):229-33.
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    10. Flory JD, Pytte CL, Hurd Y, Ferrell RE, Manuck SB. Alcohol dependence, disinhibited behavior and variation in the prodynorphin gene. Biol Psychol. 2011 Sep; 88(1):51-6.
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    11. Kamarck TW, Muldoon MF, Manuck SB, Haskett RF, Cheong J, Flory JD, Vella E. Citalopram improves metabolic risk factors among high hostile adults: results of a placebo-controlled intervention. Psychoneuroendocrinology. 2011 Aug; 36(7):1070-9.
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    12. Manuck SB, Craig AE, Flory JD, Halder I, Ferrell RE. Reported early family environment covaries with menarcheal age as a function of polymorphic variation in estrogen receptor-a. Dev Psychopathol. 2011 Feb; 23(1):69-83.
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    13. Flory JD, Bierer LM, Yehuda R. Maternal exposure to the holocaust and health complaints in offspring. Dis Markers. 2011; 30(2-3):133-9.
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    14. Yehuda R, Koenen KC, Galea S, Flory JD. The role of genes in defining a molecular biology of PTSD. Dis Markers. 2011; 30(2-3):67-76.
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    15. Yehuda R, Flory JD, Pratchett LC, Buxbaum J, Ising M, Holsboer F. Putative biological mechanisms for the association between early life adversity and the subsequent development of PTSD. Psychopharmacology (Berl). 2010 Oct; 212(3):405-17.
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    16. Koenigsberg HW, Fan J, Ochsner KN, Liu X, Guise K, Pizzarello S, Dorantes C, Tecuta L, Guerreri S, Goodman M, New A, Flory J, Siever LJ. Neural correlates of using distancing to regulate emotional responses to social situations. Neuropsychologia. 2010 May; 48(6):1813-22.
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    17. McClure MM, Harvey PD, Goodman M, Triebwasser J, New A, Koenigsberg HW, Sprung LJ, Flory JD, Siever LJ. Pergolide treatment of cognitive deficits associated with schizotypal personality disorder: continued evidence of the importance of the dopamine system in the schizophrenia spectrum. Neuropsychopharmacology. 2010 May; 35(6):1356-62.
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    18. Manuck SB, Marsland AL, Flory JD, Gorka A, Ferrell RE, Hariri AR. Salivary testosterone and a trinucleotide (CAG) length polymorphism in the androgen receptor gene predict amygdala reactivity in men. Psychoneuroendocrinology. 2010 Jan; 35(1):94-104.
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    19. Manuck SB, Phillips JE, Gianaros PJ, Flory JD, Muldoon MF. Subjective socioeconomic status and presence of the metabolic syndrome in midlife community volunteers. Psychosom Med. 2010 Jan; 72(1):35-45.
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    20. New AS, Hazlett EA, Newmark RE, Zhang J, Triebwasser J, Meyerson D, Lazarus S, Trisdorfer R, Goldstein KE, Goodman M, Koenigsberg HW, Flory JD, Siever LJ, Buchsbaum MS. Laboratory induced aggression: a positron emission tomography study of aggressive individuals with borderline personality disorder. Biol Psychiatry. 2009 Dec 15; 66(12):1107-14.
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    21. Koenigsberg HW, Siever LJ, Lee H, Pizzarello S, New AS, Goodman M, Cheng H, Flory J, Prohovnik I. Neural correlates of emotion processing in borderline personality disorder. Psychiatry Res. 2009 Jun 30; 172(3):192-9.
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    22. Flory JD, Manuck SB. Impulsiveness and cigarette smoking. Psychosom Med. 2009 May; 71(4):431-7.
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    23. McCloskey MS, New AS, Siever LJ, Goodman M, Koenigsberg HW, Flory JD, Coccaro EF. Evaluation of behavioral impulsivity and aggression tasks as endophenotypes for borderline personality disorder. J Psychiatr Res. 2009 Aug; 43(12):1036-48.
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    24. Kamarck TW, Haskett RF, Muldoon M, Flory JD, Anderson B, Bies R, Pollock B, Manuck SB. Citalopram intervention for hostility: results of a randomized clinical trial. J Consult Clin Psychol. 2009 Feb; 77(1):174-88.
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    25. Phillips JE, Marsland AL, Flory JD, Muldoon MF, Cohen S, Manuck SB. Parental education is related to C-reactive protein among female middle-aged community volunteers. Brain Behav Immun. 2009 Jul; 23(5):677-83.
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    26. Sweitzer MM, Donny EC, Dierker LC, Flory JD, Manuck SB. Delay discounting and smoking: association with the Fagerström Test for Nicotine Dependence but not cigarettes smoked per day. Nicotine Tob Res. 2008 Oct; 10(10):1571-5.
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    27. Miller CJ, Flory JD, Miller SR, Harty SC, Newcorn JH, Halperin JM. Childhood attention-deficit/hyperactivity disorder and the emergence of personality disorders in adolescence: a prospective follow-up study. J Clin Psychiatry. 2008 Sep; 69(9):1477-84.
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    28. Flory JD, Yehuda R, Grossman R, New AS, Mitropoulou V, Siever LJ. Childhood trauma and basal cortisol in people with personality disorders. Compr Psychiatry. 2009 Jan-Feb; 50(1):34-7.
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    29. Petersen KL, Marsland AL, Flory J, Votruba-Drzal E, Muldoon MF, Manuck SB. Community socioeconomic status is associated with circulating interleukin-6 and C-reactive protein. Psychosom Med. 2008 Jul; 70(6):646-52.
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    30. McClure MM, Barch DM, Flory JD, Harvey PD, Siever LJ. Context processing in schizotypal personality disorder: evidence of specificity of impairment to the schizophrenia spectrum. J Abnorm Psychol. 2008 May; 117(2):342-54.
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    31. Hall MH, Muldoon MF, Jennings JR, Buysse DJ, Flory JD, Manuck SB. Self-reported sleep duration is associated with the metabolic syndrome in midlife adults. Sleep. 2008 May; 31(5):635-43.
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    32. Bleil ME, Gianaros PJ, Jennings JR, Flory JD, Manuck SB. Trait negative affect: toward an integrated model of understanding psychological risk for impairment in cardiac autonomic function. Psychosom Med. 2008 Apr; 70(3):328-37.
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    33. Flory JD, Xu K, New AS, Finch T, Goldman D, Siever LJ. Irritable assault and variation in the COMT gene. Psychiatr Genet. 2007 Dec; 17(6):344-6.
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    34. Conklin SM, Manuck SB, Yao JK, Flory JD, Hibbeln JR, Muldoon MF. High omega-6 and low omega-3 fatty acids are associated with depressive symptoms and neuroticism. Psychosom Med. 2007 Dec; 69(9):932-4.
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    35. Gianaros PJ, Horenstein JA, Cohen S, Matthews KA, Brown SM, Flory JD, Critchley HD, Manuck SB, Hariri AR. Perigenual anterior cingulate morphology covaries with perceived social standing. Soc Cogn Affect Neurosci. 2007 Sep; 2(3):161-73.
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    36. Yehuda R, Flory JD. Differentiating biological correlates of risk, PTSD, and resilience following trauma exposure. J Trauma Stress. 2007 Aug; 20(4):435-47.
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    37. Muldoon MF, Mackey RH, Sutton-Tyrrell K, Flory JD, Pollock BG, Manuck SB. Lower central serotonergic responsivity is associated with preclinical carotid artery atherosclerosis. Stroke. 2007 Aug; 38(8):2228-33.
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    38. Flory JD, Newcorn JH, Miller C, Harty S, Halperin JM. Serotonergic function in children with attention-deficit hyperactivity disorder: relationship to later antisocial personality disorder. Br J Psychiatry. 2007 May; 190:410-4.
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    39. MacDonald AW, Carter CS, Flory JD, Ferrell RE, Manuck SB. COMT val158Met and executive control: a test of the benefit of specific deficits to translational research. J Abnorm Psychol. 2007 May; 116(2):306-12.
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    40. New AS, Hazlett EA, Buchsbaum MS, Goodman M, Mitelman SA, Newmark R, Trisdorfer R, Haznedar MM, Koenigsberg HW, Flory J, Siever LJ. Amygdala-prefrontal disconnection in borderline personality disorder. Neuropsychopharmacology. 2007 Jul; 32(7):1629-40.
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    41. Hariri AR, Brown SM, Williamson DE, Flory JD, de Wit H, Manuck SB. Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activity. J Neurosci. 2006 Dec 20; 26(51):13213-7.
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    42. Marsland AL, Petersen KL, Sathanoori R, Muldoon MF, Neumann SA, Ryan C, Flory JD, Manuck SB. Interleukin-6 covaries inversely with cognitive performance among middle-aged community volunteers. Psychosom Med. 2006 Nov-Dec; 68(6):895-903.
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    43. Neumann SA, Brown SM, Ferrell RE, Flory JD, Manuck SB, Hariri AR. Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic function. Biol Psychiatry. 2006 Nov 15; 60(10):1155-62.
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    44. Yehuda R, Flory JD, Southwick S, Charney DS. Developing an agenda for translational studies of resilience and vulnerability following trauma exposure. Ann N Y Acad Sci. 2006 Jul; 1071:379-96.
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    45. Minzenberg MJ, Xu K, Mitropoulou V, Harvey PD, Finch T, Flory JD, New AS, Goldman D, Siever LJ. Catechol-O-methyltransferase Val158Met genotype variation is associated with prefrontal-dependent task performance in schizotypal personality disorder patients and comparison groups. Psychiatr Genet. 2006 Jun; 16(3):117-24.
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    46. Brown SM, Manuck SB, Flory JD, Hariri AR. Neural basis of individual differences in impulsivity: contributions of corticolimbic circuits for behavioral arousal and control. Emotion. 2006 May; 6(2):239-45.
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    47. Flory JD, Harvey PD, Mitropoulou V, New AS, Silverman JM, Siever LJ, Manuck SB. Dispositional impulsivity in normal and abnormal samples. J Psychiatr Res. 2006 Aug; 40(5):438-47.
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    48. Muldoon MF, Mackey RH, Korytkowski MT, Flory JD, Pollock BG, Manuck SB. The metabolic syndrome is associated with reduced central serotonergic responsivity in healthy community volunteers. J Clin Endocrinol Metab. 2006 Feb; 91(2):718-21.
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    49. MacDonald AW, Goghari VM, Hicks BM, Flory JD, Carter CS, Manuck SB. A convergent-divergent approach to context processing, general intellectual functioning, and the genetic liability to schizophrenia. Neuropsychology. 2005 Nov; 19(6):814-21.
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    50. Manuck SB, Bleil ME, Petersen KL, Flory JD, Mann JJ, Ferrell RE, Muldoon MF. The socio-economic status of communities predicts variation in brain serotonergic responsivity. Psychol Med. 2005 Apr; 35(4):519-28.
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    51. Muldoon MF, Ryan CM, Sereika SM, Flory JD, Manuck SB. Randomized trial of the effects of simvastatin on cognitive functioning in hypercholesterolemic adults. Am J Med. 2004 Dec 1; 117(11):823-9.
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    52. Flory JD, Manuck SB, Matthews KA, Muldoon MF. Serotonergic function in the central nervous system is associated with daily ratings of positive mood. Psychiatry Res. 2004 Nov 30; 129(1):11-9.
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    53. Manuck SB, Flory JD, Ferrell RE, Muldoon MF. Socio-economic status covaries with central nervous system serotonergic responsivity as a function of allelic variation in the serotonin transporter gene-linked polymorphic region. Psychoneuroendocrinology. 2004 Jun; 29(5):651-68.
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    54. Flory JD, Manuck SB, Perel JM, Muldoon MF. A comparison of d, l-fenfluramine and citalopram challenges in healthy adults. Psychopharmacology (Berl). 2004 Jul; 174(3):376-80.
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    55. Muldoon MF, Mackey RH, Williams KV, Korytkowski MT, Flory JD, Manuck SB. Low central nervous system serotonergic responsivity is associated with the metabolic syndrome and physical inactivity. J Clin Endocrinol Metab. 2004 Jan; 89(1):266-71.
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    56. Mitropoulou V, Trestman RL, New AS, Flory JD, Silverman JM, Siever LJ. Neurobiologic function and temperament in subjects with personality disorders. CNS Spectr. 2003 Oct; 8(10):725-30.
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    57. Manuck SB, Flory JD, Muldoon MF, Ferrell RE. Central nervous system serotonergic responsivity and aggressive disposition in men. Physiol Behav. 2002 Dec; 77(4-5):705-9.
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    58. Flory JD, Matthews KA, Sistilli CG, Caggiula AR, Berga SL, Owens JF. Short-term suppression of ovarian function and immune measures in healthy women. Psychoneuroendocrinology. 2002 Aug; 27(6):749-68.
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    59. Flory JD, Manuck SB, Muldoon MF. Retest reliability of prolactin response to dl-fenfluramine challenge in adults. Neuropsychopharmacology. 2002 Feb; 26(2):269-72.
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    60. Matthews KA, Flory JD, Owens JF, Harris KF, Berga SL. Influence of estrogen replacement therapy on cardiovascular responses to stress of healthy postmenopausal women. Psychophysiology. 2001 May; 38(3):391-8.
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    61. Flory JD, Manuck SB, Ferrell RE, Ryan CM, Muldoon MF. Memory performance and the apolipoprotein E polymorphism in a community sample of middle-aged adults. Am J Med Genet. 2000 Dec 4; 96(6):707-11.
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    62. Bellack AS, Haas GL, Schooler NR, Flory JD. Effects of behavioural family management on family communication and patient outcomes in schizophrenia. Br J Psychiatry. 2000 Nov; 177:434-9.
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    63. Manuck SB, Flory JD, Ferrell RE, Mann JJ, Muldoon MF. A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity. Psychiatry Res. 2000 Jul 24; 95(1):9-23.
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    64. Matthews KA, Räikkönen K, Everson SA, Flory JD, Marco CA, Owens JF, Lloyd CE. Do the daily experiences of healthy men and women vary according to occupational prestige and work strain? Psychosom Med. 2000 May-Jun; 62(3):346-53.
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    65. Muldoon MF, Barger SD, Ryan CM, Flory JD, Lehoczky JP, Matthews KA, Manuck SB. Effects of lovastatin on cognitive function and psychological well-being. Am J Med. 2000 May; 108(7):538-46.
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    66. Matthews KA, Flory JD, Muldoon MF, Manuck SB. Does socioeconomic status relate to central serotonergic responsivity in healthy adults? Psychosom Med. 2000 Mar-Apr; 62(2):231-7.
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    67. Manuck SB, Flory JD, Ferrell RE, Dent KM, Mann JJ, Muldoon MF. Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene. Biol Psychiatry. 1999 Mar 1; 45(5):603-14.
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    68. Räikkönen K, Matthews KA, Flory JD, Owens JF. Effects of hostility on ambulatory blood pressure and mood during daily living in healthy adults. Health Psychol. 1999 Jan; 18(1):44-53.
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    69. Räikkönen K, Matthews KA, Flory JD, Owens JF, Gump BB. Effects of optimism, pessimism, and trait anxiety on ambulatory blood pressure and mood during everyday life. J Pers Soc Psychol. 1999 Jan; 76(1):104-13.
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    70. Flory JD, Manuck SB, Ferrell RE, Dent KM, Peters DG, Muldoon MF. Neuroticism is not associated with the serotonin transporter (5-HTTLPR) polymorphism. Mol Psychiatry. 1999 Jan; 4(1):93-6.
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    71. Muldoon MF, Sved AF, Flory JD, Perel JM, Matthews KA, Manuck SB. Inverse relationship between fenfluramine-induced prolactin release and blood pressure in humans. Hypertension. 1998 Dec; 32(6):972-5.
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    72. Manuck SB, Flory JD, McCaffery JM, Matthews KA, Mann JJ, Muldoon MF. Aggression, impulsivity, and central nervous system serotonergic responsivity in a nonpatient sample. Neuropsychopharmacology. 1998 Oct; 19(4):287-99.
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    73. Matthews KA, Berga SL, Owens JF, Flory JD. Effects of short-term suppression of ovarian hormones on cardiovascular and neuroendocrine reactivity to stress in women. Psychoneuroendocrinology. 1998 May; 23(4):307-22.
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    74. Flory JD, Mann JJ, Manuck SB, Muldoon MF. Recovery from major depression is not associated with normalization of serotonergic function. Biol Psychiatry. 1998 Mar 1; 43(5):320-6.
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    75. Muldoon MF, Barger SD, Flory JD, Manuck SB. What are quality of life measurements measuring? BMJ. 1998 Feb 14; 316(7130):542-5.
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    76. Muldoon MF, Flory JD, Marsland A, Manuck SB, Whiteside TL, Rabin B. Effects of lovastatin on the immune system. Am J Cardiol. 1997 Nov 15; 80(10):1391-4.
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    77. Muldoon MF, Marsland A, Flory JD, Rabin BS, Whiteside TL, Manuck SB. Immune system differences in men with hypo- or hypercholesterolemia. Clin Immunol Immunopathol. 1997 Aug; 84(2):145-9.
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    78. Matthews KA, Caggiula AR, McAllister CG, Berga SL, Owens JF, Flory JD, Miller AL. Sympathetic reactivity to acute stress and immune response in women. Psychosom Med. 1995 Nov-Dec; 57(6):564-71.
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    79. Flory JD, Holmes DS. Effects of an acute bout of aerobic exercise on cardiovascular and subjective responses during subsequent cognitive work. J Psychosom Res. 1991; 35(2-3):225-30.
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    80. Arnold SE, Hyman BT, Flory J, Damasio AR, Van Hoesen GW. The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease. Cereb Cortex. 1991 Jan-Feb; 1(1):103-16.
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    81. Tiwari RK, Venkatraman JT, Cinader B, Flory J, Wierzbicki A, Goh YK, Clandinin MT. Influence of genotype on the phospholipid fatty acid composition of splenic T and B lymphocytes in MRL/MpJ-lpr/lpr mice. Immunol Lett. 1988 Feb; 17(2):151-7.
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    82. Tunn S, Gurr E, Delbrück A, Buhr T, Flory J. The distribution of unsulphated and sulphated glycosaminoglycans in palmar fascia from patients with Dupuytren's disease and healthy subjects. J Clin Chem Clin Biochem. 1988 Jan; 26(1):7-14.
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067