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Last Name
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Benjamin K. Chen

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentInfectious Diseases
Address
    Other Positions
    TitleASSOCIATE PROFESSOR
    InstitutionMount Sinai
    DepartmentMicrobiology

    TitleASSOCIATE PROFESSOR
    InstitutionMount Sinai
    DepartmentPharmacology and Systems Therapeutics


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Micsenyi AM, Zony C, Alvarez RA, Durham ND, Chen BK, Klotman ME. Postintegration HIV-1 Infection of Cervical Epithelial Cells Mediates Contact-Dependent Productive Infection of T Cells. J Infect Dis. 2013 Dec; 208(11):1756-67.
      View in: PubMed
    2. Chan YY, Kalpana S, Chang WC, Chang WC, Chen BK. Expression of aryl hydrocarbon receptor nuclear translocator enhances cisplatin resistance by upregulating MDR1 expression in cancer cells. Mol Pharmacol. 2013 Oct; 84(4):591-602.
      View in: PubMed
    3. Ko SC, Huang CR, Shieh JM, Yang JH, Chang WC, Chen BK. Epidermal growth factor protects squamous cell carcinoma against cisplatin-induced cytotoxicity through increased interleukin-1ß expression. PLoS One. 2013; 8(2):e55795.
      View in: PubMed
    4. Dale BM, Alvarez RA, Chen BK. Mechanisms of enhanced HIV spread through T-cell virological synapses. Immunol Rev. 2013 Jan; 251(1):113-24.
      View in: PubMed
    5. Chen BK. T cell virological synapses and HIV-1 pathogenesis. Immunol Res. 2012 Dec; 54(1-3):133-9.
      View in: PubMed
    6. Durham ND, Yewdall AW, Chen P, Lee R, Zony C, Robinson JE, Chen BK. Neutralization resistance of virological synapse-mediated HIV-1 Infection is regulated by the gp41 cytoplasmic tail. J Virol. 2012 Jul; 86(14):7484-95.
      View in: PubMed
    7. Costantino CM, Gupta A, Yewdall AW, Dale BM, Devi LA, Chen BK. Cannabinoid receptor 2-mediated attenuation of CXCR4-tropic HIV infection in primary CD4+ T cells. PLoS One. 2012; 7(3):e33961.
      View in: PubMed
    8. Dale BM, McNerney GP, Thompson DL, Hubner W, de Los Reyes K, Chuang FY, Huser T, Chen BK. Cell-to-cell transfer of HIV-1 via virological synapses leads to endosomal virion maturation that activates viral membrane fusion. Cell Host Microbe. 2011 Dec 15; 10(6):551-62.
      View in: PubMed
    9. Wang JY, Chen BK, Wang YS, Tsai YT, Chen WC, Chang WC, Hou MF, Wu YC, Chang WC. Involvement of store-operated calcium signaling in EGF-mediated COX-2 gene activation in cancer cells. Cell Signal. 2012 Jan; 24(1):162-9.
      View in: PubMed
    10. Del Portillo A, Tripodi J, Najfeld V, Wodarz D, Levy DN, Chen BK. Multiploid inheritance of HIV-1 during cell-to-cell infection. J Virol. 2011 Jul; 85(14):7169-76.
      View in: PubMed
    11. Chen P, Chen BK, Mosoian A, Hays T, Ross MJ, Klotman PE, Klotman ME. Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells. J Am Soc Nephrol. 2011 Mar; 22(3):496-507.
      View in: PubMed
    12. Dale B, McNerney GP, Thompson DL, Hübner W, Huser T, Chen BK. Visualizing cell-to-cell transfer of HIV using fluorescent clones of HIV and live confocal microscopy. J Vis Exp. 2010; (44).
      View in: PubMed
    13. Tuyama AC, Hong F, Saiman Y, Wang C, Ozkok D, Mosoian A, Chen P, Chen BK, Klotman ME, Bansal MB. Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis. Hepatology. 2010 Aug; 52(2):612-22.
      View in: PubMed
    14. Dale BM, McNerney GP, Hübner W, Huser TR, Chen BK. Tracking and quantitation of fluorescent HIV during cell-to-cell transmission. Methods. 2011 Jan; 53(1):20-6.
      View in: PubMed
    15. Huang WC, Chen ST, Chang WC, Chang KY, Chang WC, Chen BK. Involvement of aryl hydrocarbon receptor nuclear translocator in EGF-induced c-Jun/Sp1-mediated gene expression. Cell Mol Life Sci. 2010 Oct; 67(20):3523-33.
      View in: PubMed
    16. McNerney GP, Hübner W, Chen BK, Huser T. Manipulating CD4+ T cells by optical tweezers for the initiation of cell-cell transfer of HIV-1. J Biophotonics. 2010 Apr; 3(4):216-23.
      View in: PubMed
    17. Hübner W, McNerney GP, Chen P, Dale BM, Gordon RE, Chuang FY, Li XD, Asmuth DM, Huser T, Chen BK. Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science. 2009 Mar 27; 323(5922):1743-7.
      View in: PubMed
    18. Chang KY, Shen MR, Lee MY, Wang WL, Su WC, Chang WC, Chen BK. Epidermal growth factor-activated aryl hydrocarbon receptor nuclear translocator/HIF-1{beta} signal pathway up-regulates cyclooxygenase-2 gene expression associated with squamous cell carcinoma. J Biol Chem. 2009 Apr 10; 284(15):9908-16.
      View in: PubMed
    19. Chen CJ, Chang WC, Chen BK. Attenuation of c-Jun and Sp1 expression and p300 recruitment to gene promoter confers the trichostatin A-induced inhibition of 12(S)-lipoxygenase expression in EGF-treated A431 cells. Eur J Pharmacol. 2008 Sep 4; 591(1-3):36-42.
      View in: PubMed
    20. Tsou JH, Chang KY, Wang WC, Tseng JT, Su WC, Hung LY, Chang WC, Chen BK. Nucleolin regulates c-Jun/Sp1-dependent transcriptional activation of cPLA2alpha in phorbol ester-treated non-small cell lung cancer A549 cells. Nucleic Acids Res. 2008 Jan; 36(1):217-27.
      View in: PubMed
    21. Hübner W, Chen P, Del Portillo A, Liu Y, Gordon RE, Chen BK. Sequence of human immunodeficiency virus type 1 (HIV-1) Gag localization and oligomerization monitored with live confocal imaging of a replication-competent, fluorescently tagged HIV-1. J Virol. 2007 Nov; 81(22):12596-607.
      View in: PubMed
    22. Chen P, Hübner W, Spinelli MA, Chen BK. Predominant mode of human immunodeficiency virus transfer between T cells is mediated by sustained Env-dependent neutralization-resistant virological synapses. J Virol. 2007 Nov; 81(22):12582-95.
      View in: PubMed
    23. Furtado GC, Marinkovic T, Martin AP, Garin A, Hoch B, Hubner W, Chen BK, Genden E, Skobe M, Lira SA. Lymphotoxin beta receptor signaling is required for inflammatory lymphangiogenesis in the thyroid. Proc Natl Acad Sci U S A. 2007 Mar 20; 104(12):5026-31.
      View in: PubMed
    24. Chen BK, Huang CC, Chang WC, Chen YJ, Kikkawa U, Nakahama K, Morita I, Chang WC. PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells. Mol Biol Cell. 2007 Mar; 18(3):1118-27.
      View in: PubMed
    25. Hübner W, Chen BK. Inhibition of viral assembly in murine cells by HIV-1 matrix. Virology. 2006 Aug 15; 352(1):27-38.
      View in: PubMed
    26. Chen P, Hübner W, Riviere K, Liu YX, Chen BK. Chimeric HIV-1 containing SIV matrix exhibit enhanced assembly in murine cells and replicate in a cell-type-dependent manner in human T cells. Virology. 2006 May 25; 349(1):1-12.
      View in: PubMed
    27. Chen LC, Chen BK, Chang WC. Activating protein 1-mediated cyclooxygenase-2 expression is independent of N-terminal phosphorylation of c-Jun. Mol Pharmacol. 2005 Jun; 67(6):2057-69.
      View in: PubMed
    28. Chen LC, Chen BK, Chang JM, Chang WC. Essential role of c-Jun induction and coactivator p300 in epidermal growth factor-induced gene expression of cyclooxygenase-2 in human epidermoid carcinoma A431 cells. Biochim Biophys Acta. 2004 Jul 5; 1683(1-3):38-48.
      View in: PubMed
    29. Liu YW, Tseng HP, Chen LC, Chen BK, Chang WC. Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophages. J Immunol. 2003 Jul 15; 171(2):821-8.
      View in: PubMed
    30. Chen BK, Tsai TY, Huang HS, Chen LC, Chang WC, Tsai SB, Chang WC. Functional role of extracellular signal-regulated kinase activation and c-Jun induction in phorbol ester-induced promoter activation of human 12(S)-lipoxygenase gene. J Biomed Sci. 2002 Mar-Apr; 9(2):156-65.
      View in: PubMed
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067