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Institution

D. Stave Kohtz

TitleASSOCIATE PROFESSOR
InstitutionMount Sinai
DepartmentPathology
Address
    Other Positions
    TitleASSOCIATE PROFESSOR
    InstitutionMount Sinai
    DepartmentOncological Sciences


     Bibliographic 
     selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kinoshita Y, Kalir T, Dottino P, Kohtz DS. Nuclear distributions of NUP62 and NUP214 suggest architectural diversity and spatial patterning among nuclear pore complexes. PLoS One. 2012; 7(4):e36137.
      View in: PubMed
    2. Kinoshita Y, Kalir T, Rahaman J, Dottino P, Kohtz DS. Alterations in nuclear pore architecture allow cancer cell entry into or exit from drug-resistant dormancy. Am J Pathol. 2012 Jan; 180(1):375-89.
      View in: PubMed
    3. Wu M, Kafanas A, Gan L, Kohtz DS, Zhang L, Genden E, Burstein DE. Feasibility of immunocytochemical detection of tumor markers (XIAP, phosphohistone H1 and p63) in FNA cellblock samples from head and neck squamous cell carcinoma. Diagn Cytopathol. 2008 Nov; 36(11):797-800.
      View in: PubMed
    4. Alapat DV, Chaudhry T, Ardakany-Taghavi R, Kohtz DS. Fiber-types of sarcomeric proteins expressed in cultured myogenic cells are modulated by the dose of myogenin activity. Cell Signal. 2009 Jan; 21(1):128-35.
      View in: PubMed
    5. Wang QJ, Ding Y, Kohtz DS, Kohtz S, Mizushima N, Cristea IM, Rout MP, Chait BT, Zhong Y, Heintz N, Yue Z. Induction of autophagy in axonal dystrophy and degeneration. J Neurosci. 2006 Aug 2; 26(31):8057-68.
      View in: PubMed
    6. Burstein DE, Nagi C, Kohtz DS, Lee L, Wang B. Immunodetection of GLUT1, p63 and phospho-histone H1 in invasive head and neck squamous carcinoma: correlation of immunohistochemical staining patterns with keratinization. Histopathology. 2006 May; 48(6):717-22.
      View in: PubMed
    7. Burstein DE, Nagi C, Kohtz DS, Lumerman H, Wang BY. Immunohistochemical detection of GLUT1, p63 and phosphorylated histone H1 in head and neck squamous intraepithelial neoplasia: evidence for aberrations in hypoxia-related, cell cycle- and stem-cell-regulatory pathways. Histopathology. 2006 May; 48(6):708-16.
      View in: PubMed
    8. Liu H, Barr SM, Chu C, Kohtz DS, Kinoshita Y, Johnson EM. Functional interaction of Puralpha with the Cdk2 moiety of cyclin A/Cdk2. Biochem Biophys Res Commun. 2005 Mar 25; 328(4):851-7.
      View in: PubMed
    9. Good PF, Alapat D, Hsu A, Chu C, Perl D, Wen X, Burstein DE, Kohtz DS. A role for semaphorin 3A signaling in the degeneration of hippocampal neurons during Alzheimer's disease. J Neurochem. 2004 Nov; 91(3):716-36.
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    10. Chu C, Alapat D, Wen X, Timo K, Burstein D, Lisanti M, Shears S, Kohtz DS. Ectopic expression of murine diphosphoinositol polyphosphate phosphohydrolase 1 attenuates signaling through the ERK1/2 pathway. Cell Signal. 2004 Sep; 16(9):1045-59.
      View in: PubMed
    11. Unger P, Ewart M, Wang BY, Gan L, Kohtz DS, Burstein DE. Expression of p63 in papillary thyroid carcinoma and in Hashimoto's thyroiditis: a pathobiologic link? Hum Pathol. 2003 Aug; 34(8):764-9.
      View in: PubMed
    12. Kafanas A, Wang BY, Kalir T, Gan L, Bodian C, Fish H, Kohtz DS, Burstein DE. Immunohistochemical visualization of histone H1 phosphorylation in squamous intraepithelial lesions of the gynecologic tract. Hum Pathol. 2003 Feb; 34(2):166-73.
      View in: PubMed
    13. Wang BY, Gil J, Kaufman D, Gan L, Kohtz DS, Burstein DE. P63 in pulmonary epithelium, pulmonary squamous neoplasms, and other pulmonary tumors. Hum Pathol. 2002 Sep; 33(9):921-6.
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    14. Burstein DE, Oami S, Dembitzer F, Chu C, Cernaianu G, Leytin A, Misilim E, Jammula SR, Strauchen J, Kohtz DS. Monoclonal antibody specific for histone H1 phosphorylated by cyclin-dependent kinases: a novel immunohistochemical probe of proliferation and neoplasia. Mod Pathol. 2002 Jul; 15(7):705-11.
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    15. Chu C, Kohtz DS. Identification of the E2A gene products as regulatory targets of the G1 cyclin-dependent kinases. J Biol Chem. 2001 Mar 16; 276(11):8524-34.
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    16. Moschella MC, Menzies K, Tsao L, Lieb MA, Kohtz JD, Kohtz DS, Taubman MB. SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation. Gene Expr. 1999; 8(1):59-66.
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    17. Engelman JA, Chu C, Lin A, Jo H, Ikezu T, Okamoto T, Kohtz DS, Lisanti MP. Caveolin-mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo. A role for the caveolin-scaffolding domain. FEBS Lett. 1998 May 29; 428(3):205-11.
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    18. Scherer PE, Lewis RY, Volonte D, Engelman JA, Galbiati F, Couet J, Kohtz DS, van Donselaar E, Peters P, Lisanti MP. Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo. J Biol Chem. 1997 Nov 14; 272(46):29337-46.
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    19. Schecter AD, Giesen PL, Taby O, Rosenfield CL, Rossikhina M, Fyfe BS, Kohtz DS, Fallon JT, Nemerson Y, Taubman MB. Tissue factor expression in human arterial smooth muscle cells. TF is present in three cellular pools after growth factor stimulation. J Clin Invest. 1997 Nov 1; 100(9):2276-85.
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    20. Chu C, Cogswell J, Kohtz DS. MyoD functions as a transcriptional repressor in proliferating myoblasts. J Biol Chem. 1997 Feb 7; 272(6):3145-8.
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    21. Song KS, Scherer PE, Tang Z, Okamoto T, Li S, Chafel M, Chu C, Kohtz DS, Lisanti MP. Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins. J Biol Chem. 1996 Jun 21; 271(25):15160-5.
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    22. Tang Z, Scherer PE, Okamoto T, Song K, Chu C, Kohtz DS, Nishimoto I, Lodish HF, Lisanti MP. Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle. J Biol Chem. 1996 Jan 26; 271(4):2255-61.
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    23. Rao SS, Kohtz DS. Positive and negative regulation of D-type cyclin expression in skeletal myoblasts by basic fibroblast growth factor and transforming growth factor beta. A role for cyclin D1 in control of myoblast differentiation. J Biol Chem. 1995 Feb 24; 270(8):4093-100.
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    24. Rao SS, Chu C, Kohtz DS. Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators. Mol Cell Biol. 1994 Aug; 14(8):5259-67.
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    25. Shue G, Kohtz DS. Structural and functional aspects of basic helix-loop-helix protein folding by heat-shock protein 90. J Biol Chem. 1994 Jan 28; 269(4):2707-11.
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    26. Cole F, Fasy TM, Rao SS, de Peralta MA, Kohtz DS. Growth factors that repress myoblast differentiation sustain phosphorylation of a specific site on histone H1. J Biol Chem. 1993 Jan 25; 268(3):1580-5.
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    27. Shaknovich R, Shue G, Kohtz DS. Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84). Mol Cell Biol. 1992 Nov; 12(11):5059-68.
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    28. Cole F, Timo KS, Kohtz DS. Monoclonal antibodies identify a possible regulatory domain of MyoD1. J Cell Biochem. 1992 Oct; 50(2):130-42.
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    29. Feghali R, Karsch-Mizrachi I, Leinwand LA, Kohtz DS. Four sarcomeric myosin heavy chain genes are expressed by human fetal skeletal muscle cells differentiating in culture. Gene Expr. 1992; 2(1):49-58.
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    30. Kohtz DS, Cole F, Wong ML, Hsu MT. Infection and inhibition of differentiation of human fetal skeletal myoblasts by adenovirus. Virology. 1991 Oct; 184(2):569-79.
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    31. Kohtz DS, Puszkin S. Novel NGF-induced proteins in PC12 cells: immunological evidence for their presence in brain nerve endings using a single monoclonal antibody. J Neurosci Res. 1990 Nov; 27(3):307-13.
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    32. Kohtz DS, Hanson V, Puszkin S. Novel proteins mediate an interaction between clathrin-coated vesicles and polymerizing actin filaments. Eur J Biochem. 1990 Sep 11; 192(2):291-8.
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    33. Silva WI, Kohtz DS, Puszkin S. Immunoprecipitation of bovine brain membranes enriched in M1 and M2 muscarinic receptors with monoclonal antibody 10C7. Neurosci Lett. 1990 May 18; 113(1):89-94.
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    34. Puszkin S, Kohtz JD, Schook WJ, Kohtz DS. Clathrin-coated vesicle subtypes in mammalian brain tissue: detection of polypeptide heterogeneity by immunoprecipitation with monoclonal antibodies. J Neurochem. 1989 Jul; 53(1):51-63.
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    35. Kohtz DS, Dische NR, Inagami T, Goldman B. Growth and partial differentiation of presumptive human cardiac myoblasts in culture. J Cell Biol. 1989 Mar; 108(3):1067-78.
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    36. Kohtz DS, Puszkin S. Phosphorylation of tubulin by casein kinase II regulates its binding to a neuronal protein (NP 185) associated with brain coated vesicles. J Neurochem. 1989 Jan; 52(1):285-95.
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    37. Feldman M, Kohtz DS, Kleinberg DL. Isolation and characterization of monoclonal antibodies against ribonuclease inhibitor. Biochem Biophys Res Commun. 1988 Nov 30; 157(1):286-94.
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    38. Appel JD, Fasy TM, Kohtz DS, Kohtz JD, Johnson EM. Asbestos fibers mediate transformation of monkey cells by exogenous plasmid DNA. Proc Natl Acad Sci U S A. 1988 Oct; 85(20):7670-4.
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    39. Kohtz DS, Puszkin S. A neuronal protein (NP185) associated with clathrin-coated vesicles. Characterization of NP185 with monoclonal antibodies. J Biol Chem. 1988 May 25; 263(15):7418-25.
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    40. Kohtz DS, Altman A, Kohtz JD, Puszkin S. Immunological and structural homology between human T-cell leukemia virus type I envelope glycoprotein and a region of human interleukin-2 implicated in binding the beta receptor. J Virol. 1988 Feb; 62(2):659-62.
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    41. Schook WJ, Parker C, Silva WI, Kohtz DS, Puszkin S. Phosphorylation characteristics of brain clathrin-coated vesicle endogenous proteins. J Neurochem. 1987 Aug; 49(2):434-41.
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    42. Kohtz DS, Georgieva-Hanson V, Kohtz JD, Schook WJ, Puszkin S. Mapping two functional domains of clathrin light chains with monoclonal antibodies. J Cell Biol. 1987 Apr; 104(4):897-903.
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    43. Colucci G, Kohtz DS, Waksal SD. Preparation and characterization of human monoclonal antibodies directed against the hepatitis B virus surface antigen. Liver. 1986 Jun; 6(3):145-52.
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    44. Gibson MJ, Kohtz DS. The effects of the GnRH agonist, [(imBzl)-D-His6, Pro9-NEt]-GnRH, on the response to stress in rats. Contraception. 1985 Jan; 31(1):91-9.
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    45. Kohtz DS, Waksal SD. Growth factors and leukemogenesis. A role for biological mimicry in biological transformation. Surv Immunol Res. 1984; 3(1):34-8.
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    46. Verderame MF, Kohtz DS, Pollack RE. 94,000- and 100,000-molecular-weight simian virus 40 T-antigens are associated with the nuclear matrix in transformed and revertant mouse cells. J Virol. 1983 May; 46(2):575-83.
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    Mount Sinai Profiles is managed by Conduits - The Institutes for Translational Sciences at Icahn School of Medicine, supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences of the National Institutes of Health through Grant Number UL1TR000067